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Open Journal of Clinical Diagnostics 2014年第3期4卷 123-129页

作者： Barbro H. Skogman pia forsberg Sirkka Vene Britt Akerlind 不详

Lyme neuroborreliosis (LNB) in children is a challenging diagnosis based on clinical manifestations and laboratory findings. The aim of this study was to investigate whether herpes simplex virus (HSV) 1 or 2, varicella zoster virus (VZV), enterovirus or tick-borne encephalitis virus (TBEV) could be identified in cerebrospinal fluid (CSF) or serum from children being evaluated for LNB, in order to elucidate whether such infectious diseases may be missed by the clinician. Methods: Ninety-nine pediatric patients (n = 99) were retrospectively included from a previous study on LNB in southeast of Sweden. They had been diagnosed as “Possible LNB” or “Not determined” due to negative Borrelia antibody index in CSF. Routine polymerase chain reaction (PCR) methods were used for detection of herpes viral RNA or enteroviral DNA in CSF. An ELISA assay was used for detection of anti-TBEV antibodies (IgM and IgG) in serum. Results: One patient showed elevated anti-TBEV IgM and IgG antibodies in serum, indicating a current TBE infection. No positive PCR reactions for HSV 1 or 2, VZV or enterovirus were detected in CSF from any of the patients. In conclusion, our results suggest that undiagnosed herpes- or enteroviral infections are unlikely to explain CNS symptoms in children being evaluated for LNB, whereas missed TBE infections may occur. TBEV serology should be included when evaluating children for LNB in TBE endemic areas.

关键词： Enterovirus Herpes Simplex Virus Lyme Neuroborreliosis Varicella Zoster Virus Tick-Borne Encephalitis

Aetiology of Tick-Borne Infections in an Adult Swedish Population—Are Co-Infections with Multiple Agents Common?

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Open Journal of Clinical Diagnostics 2014年第1期4卷 31-40页

作者： Marika Nordberg pia forsberg Johan Berglund Anneli Bjoersdorff Jan Ernerudh Ulf Garpmo Mats Haglund Kenneth Nilsson Ingvar Eliasson Infectious Medicine Department of Clinical and Experimental MedicineFaculty of Health SciencesLinkoping UniversityLinkopingSweden Department of Infectious Diseases County Council of OstergotlandLinkopingSweden Blekinge Institute of Technology School of Health ScienceKarlskronaSweden Djursjukhusgruppen DanderydSweden Clinical Immunology Department of Clinical and Experimental MedicineFaculty of Health SciencesLinkoping UniversityDepartment of Clinical Immunology and Transfusion MedicineCounty Council of OstergotlandLinkopingSweden Department of Clinical Microbiology Kalmar County HospitalKalmarSweden Department of Infectious Diseases Kalmar County HospitalKalmarSweden Unit of Clinical Microbiology/Infectious Diseases Department of Medical SciencesUppsala UniversityUppsalaSweden Department of Laboratory Medicine Norra Alvsborg County HospitalTrollhattanSweden

In Scandinavia, tick-borne infections affecting humans include Lyme borreliosis (LB), tick-borne encephalitis (TBE) and human granulocytic anaplasmosis (HGA). Each of these infections can present with unspecific symptoms. In this prospective clinical study, we recruited patients based on two independent inclusion criteria;1) patients with unspecific symptoms, i.e. fever (≥38.0℃) or a history of feverishness and/or any combination of headache, myalgia or arthralgia and 2) patients with erythema migrans (EM), following an observed tick bite or tick exposure within one month prior to onset of symptoms. A total of 206 patients fulfilled the study. Among these, we could identify 186 cases of LB (174 with EM), 18 confirmed and two probable cases of HGA and two cases of TBE. Thirteen of the HGA cases presented without fever. Furthermore, 22 of the EM patients had a sub-clinical co-infection with Anaplasma phagocytophilum, based on serology. Both TBE cases had co-infections, one with Borrelia burgdorferi and one with Anaplasma phagocytophilum. We conclude that it is important to consider several causative agents and possible co-infections in the clinical management of infectious diseases where ticks may be suspected as vectors.

关键词： Epidemiology Tick-Borne Infections Tick-Borne Encephalitis Lyme Borreliosis Human Granulocytic Anaplasmosis

Bragg reflectors based on alternate RHTL-LHTL structures

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第1期7卷 81-84页

作者：邹勇卓胡鑫姚军 forsberg Erik State Key Laboratory of Modern Optical Instrumentation Zhejiang UniversityHangzhou 310027 China

New types of Bragg reflectors, multilayered periodic structures, based on alternating left-handed transmission line (LHTL) and right-handed transmission line (RHTL) are proposed. These new structures based on ideal microstrip TLs and L-C lumped elements, are designed and analyzed. We report on unusual narrow transmission bands in such kind of structures. In such multilayered structures both Bragg reflectance and the Fabry-Perot resonance exist and the phenomenon of unusual transmission is a result of competition between these two transmission effects, in which the Fabry-Perot resonance is dominant. According to our simulation results we find that this unusual transmission property exits no matter if the electrical length of the LHTL layer cancels the electrical length of the RHTL layer or not.

关键词：布拉格反射镜左旋材料右旋材料输电线路 RHTL LHTL

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基于精密单点定位技术的航空测量应用实践

武汉大学学报（信息科学版） 2006年第1期31卷 19-22,46页

作者：张小红刘经南 Rene forsberg 武汉大学测绘学院武汉市珞喻路129号430079 武汉大学校长办公室武汉市珞珈山430072 丹麦空间研究中心

讨论了基于精密单点定位技术来实现无地面基准站的航空测量。计算结果表明,用观测值的验后残差计算得到的实测动态及静态模拟动态进行精密单点定位的三维RMS均优于3 cm;用动态数据精密单点定位的结果同多基准站的双差解求较差计算出的R... 详细信息

讨论了基于精密单点定位技术来实现无地面基准站的航空测量。计算结果表明,用观测值的验后残差计算得到的实测动态及静态模拟动态进行精密单点定位的三维RMS均优于3 cm;用动态数据精密单点定位的结果同多基准站的双差解求较差计算出的RMS,南北分量和东西分量均优于5 cm,高程分量优于10cm;用基准站的静态数据模拟动态单点定位解算得到的坐标同已知坐标求较差计算出的RMS,南北分量和东西分量均优于3 cm,高程分量优于5 cm。

关键词：精密动态单点定位无地面控制点航空测量

Direct generation of linearly polarized photon emission with designated orientations from site-controlled InGaN quantum dots

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Light(Science & Applications) 2014年第1期3卷 323-329页

作者： Anders Lundskog Chih-Wei Hsu K Fredrik Karlsson Supaluck Amloy Daniel Nilsson Urban forsberg Per Olof Holtz Erik Janzen Department of Physics Chemistry and Biology(IFM) Linkoping UniversitySE-58183 LinkopingSweden Department of Physics Faculty of ScienceThaksin UniversityPhattalung 93110Thailand

Semiconductor quantum dots(QDs)have been demonstrated viable for efficient light emission applications,in particular for the emission of single photons on ***,the preparation of QDs emitting photons with predefined and deterministic polarization vectors has proven *** to linearly polarized photons is essential for various *** this report,a novel concept to directly generate linearly-polarized photons is *** concept is based on InGaN QDs grown on top of elongated GaN hexagonal pyramids,by which the predefined elongation determines the polarization vectors of the emitted photons from the *** growth scheme should allow fabrication of ultracompact arrays of photon emitters,with a controlled polarization direction for each individual emitter.

关键词： GaN InGaN photoluminescence polarized emission quantum dot

Läxhjälp as Shadow Education in Sweden:The Logic of Equality in“A School for All”

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ECNU Review of Education 2021年第3期4卷 494-519页

作者： Eva forsberg Stina Hallsen Marie Karlsson Helen Melander Bowden Tatiana Mikhaylova Johanna Svahn Uppsala University Uppsala University and University of Gavle

Purpose:Taking läxhjälp/homework support in Sweden as a case,this article aims to further explore shadow education,especially as a pedagogical object from curriculum theory ***/Approach/Methods:Approaches including policy analyses,ethnomethodological work based on video-recorded interaction,and narratives have produced empirically grounded *** use examples from several substudies and analyze the reentry and regulation of supplementary education and how tutors and tutees interact in tutoring settings and negotiate identities in läxhjälp as well as the relation to regular ***:Läxhjälp is conditioned by the logic of equality and changes in the governance of läxhjä*** proliferation of different kinds of tutoring practices provided by various organizations calls for a broad definition of shadow *** curriculum as boundary object,equality and academic success are *** settings and spatiotemporal arrangements affect modes of interaction,distribution of epistemic authority,and negotiations of ***/Value:With Sweden as a case,it is possible to explore shadow education in a new context,the Scandinavian welfare state,and its history of comprehensive ***,ethnomethodological interaction and narrative studies and curriculum perspectives are seldom employed within research on shadow education.A number of critical key boundary objects are identified.

关键词： Boundary object curriculum theory homework support identities interaction shadow education

Integrating MEMS and ICs

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Microsystems & Nanoengineering 2015年第1期1卷 165-180页

作者： Andreas C.Fischer Fredrik forsberg Martin Lapisa Simon J.Bleiker Göran Stemme Niclas Roxhed Frank Niklaus Department of Micro and Nanosystems School of Electrical EngineeringKTH Royal Institute of TechnologySE-10044 StockholmSweden

The majority of microelectromechanical system(MEMS)devices must be combined with integrated circuits(ICs)for operation in larger electronic *** MEMS transducers sense or control physical,optical or chemical quantities,ICs typically provide functionalities related to the signals of these transducers,such as analog-to-digital conversion,amplification,filtering and information processing as well as communication between the MEMS transducer and the outside ***,the vast majority of commercial MEMS products,such as accelerometers,gyroscopes and micro-mirror arrays,are integrated and packaged together with *** are a variety of possible methods of integrating and packaging MEMS and IC components,and the technology of choice strongly depends on the device,the field of application and the commercial *** this review paper,traditional as well as innovative and emerging approaches to MEMS and IC integration are *** include approaches based on the hybrid integration of multiple chips(multi-chip solutions)as well as system-on-chip solutions based on wafer-level monolithic integration and heterogeneous integration *** are important technological building blocks for the‘More-Than-Moore’paradigm described in the International Technology Roadmap for *** this paper,the various approaches are categorized in a coherent manner,their merits are discussed,and suitable application areas and implementations are critically *** implications of the different MEMS and IC integration approaches for packaging,testing and final system costs are reviewed.

关键词： cofabrication platforms integrated circuits(ICs) microelectromechanical system(MEMS) More-Than-Moore multichip modules(MCMs) system-in-package(SiP) system-on-chip(SoC) three-dimensional(3D)heterogeneous integration

耶尔森氏菌yopE位区的基因分析:一种新的调节yopE表达的保守位点——yerA

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地方病译丛 1992年第6期13卷 9-11页

作者： A.forsberg 戴翔

耶尔森氏菌属的人类致病菌均携有毒力必需的相关质粒。Cornelis 等氏已于最近证实了小肠结肠炎杆菌的 irF(lcrF)基因是一种直接作用于 yopH 基因上的转录活化子。已构建了数株假结核杆菌 YPⅢ(pIBl)yopE和 yopH 的特异突变体并发现其对... 详细信息

耶尔森氏菌属的人类致病菌均携有毒力必需的相关质粒。Cornelis 等氏已于最近证实了小肠结肠炎杆菌的 irF(lcrF)基因是一种直接作用于 yopH 基因上的转录活化子。已构建了数株假结核杆菌 YPⅢ(pIBl)yopE和 yopH 的特异突变体并发现其对小鼠模型无毒。进一步的研究表明 yopE 基因与对培养的 Hela 细胞的细胞毒作用有关,yopH基因与抗小鼠腹膜巨噬细胞的吞噬能力有关。Biot 和 Cornelis 二氏证实假结核菌

关键词：耶尔辛杆菌基因基因表达

Characterization of a novel human papillomavirus type representing a new species within the genus Gamma

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Characterization of a novel human papillomavirus type repres...

Manufacture and characterization of graphene membranes with suspended silicon proof masses for MEMS and NEMS applications

24th International Papillomavirus Conference and Clinical Workshop

作者： Johanna Kullander Martin forsberg Joakim Dillner Lund University Lund University Lund University

＜正＞A novel HPV type,FA137,was isolated from a squamous cell carcinoma（SCC）with multiple displacement amplification（MDA） using primers generic to any HPV The complete genome of FA137 was 7346 bp with a typical genomic organization The most closely related type was HPV4,but with only 64.4% similarity in the ***,FA137 belongs to a new species within the genus Gamma.

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Microsystems & Nanoengineering 2020年第1期6卷 1050-1066页

作者： Xuge Fan Anderson D.Smith Fredrik forsberg Stefan Wagner Stephan Schroder Sayedeh Shirin Afyouni Akbari Andreas C.Fischer Luis Guillermo Villanueva Mikael Ostling Max C.Lemme Frank Niklaus Division of Micro and Nanosystems School of Electrical Engineering and Computer ScienceKTH Royal Institute of TechnologySE-10044 StockholmSweden Division of Integrated Devices and Circuits School of Electrical Engineering and Computer ScienceKTH Royal Institute of TechnologySE-16440 KistaSweden Faculty of Electrical Engineering and Information Technology RWTH Aachen UniversityOtto-Blumenthal-Str.2552074 AachenGermany Advanced NEMS Group École Polytechnique Fédérale de Lausanne(EPFL)1015 LausanneSwitzerland Silex Microsystems AB 17526 JärfällaSweden AMO GmbH Advanced Microelectronic Center Aachen(AMICA)Otto-Blumnethal-Str.2552074 AachenGermany

Graphene’s unparalleled strength,chemical stability,ultimate surface-to-volume ratio and excellent electronic properties make it an ideal candidate as a material for membranes in micro-and nanoelectromechanical systems(MEMS and NEMS).However,the integration of graphene into MEMS or NEMS devices and suspended structures such as proof masses on graphene membranes raises several technological challenges,including collapse and rupture of the *** have developed a robust route for realizing membranes made of double-layer CVD graphene and suspending large silicon proof masses on membranes with high *** have demonstrated the manufacture of square graphene membranes with side lengths from 7µm to 110µm,and suspended proof masses consisting of solid silicon cubes that are from 5µm×5µm×16.4µm to 100µm×100µm×16.4µm in *** approach is compatible with wafer-scale MEMS and semiconductor manufacturing technologies,and the manufacturing yields of the graphene membranes with suspended proof masses were>90%,with>70%of the graphene membranes having>90%graphene area without visible *** measured resonance frequencies of the realized structures ranged from tens to hundreds of kHz,with quality factors ranging from 63 to *** graphene membranes with suspended proof masses were extremely robust,and were able to withstand indentation forces from an atomic force microscope(AFM)tip of up to~*** proposed approach for the reliable and large-scale manufacture of graphene membranes with suspended proof masses will enable the development and study of innovative NEMS devices with new functionalities and improved performances.

关键词： proof characterization hundreds