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Bemisia tabaci： The current situation in the UK and the prospect of developing strategies for eradication using entomopathogens

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Insect Science 2011年第1期18卷 1-10页

作者： Andrew G. S. Cuthbertson Lisa F. Blackburn Dominic p. Eyre Raymond j.C. Cannon judith Miller phil Northing The Food and Environment Research Agency Sand Hutton York UK

The sweetpotato whitefly, Bemisia tabaci （Gennadius）（Hemiptera： Aleyrodidae） remains a serious threat to crops worldwide. The damaging B-biotype is of specific economic concern because it is an effective vector of over 111 viruses from several fam- ilies, particularly geminiviruses. Bemisia tabaci is regularly intercepted on plants coming into the UK where it is subjected to a policy of eradication. The UK maintains protective Zone status against this pest. A main pathway of entry of B. tabaci into the protected Zone involves propagating material, especially poinsettia （Euphorbia pulcherrima）. With increased insecticide resistance continuously being recorded, B. tabaci is becoming more difficult to control/eradicate. Recent research involving both entomopathogenic nematodes and fungi is showing much potential for the development of control programs for this pest. Both the nematode Steinernemafeltiae and the fungus Lecanicillium muscarium have been shown to be most effective against second instar B. tabaci. Fine-tuning of the environmental conditions required has also increased their efficacy. The entomopathogens have also shown a high level of compatibility with chemical insecticides, all increasing their potential to be incorporated into control strategies against B. tabaci.

关键词： biocontrol entomopathogenic nematodes entomopathogenic fungi insecticide resistance whitefly

二维应变和应变率成像技术监测心脏移植术后急性排异反应

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中国医学影像技术 2009年第7期25卷 1179-1182页

作者：何怡华李治安谷孝艳 nixon j V(Ian) 首都医科大学附属北京安贞医院超声诊断科北京100029 弗吉尼亚联邦大学心脏内科里士满23298

目的探讨超声心动图二维应变和应变率成像技术在监测心脏移植术后急性排异反应方面的价值。方法对25例心脏移植患者在活检12h内行超声心动图检查。急性排异反应0级为A组(n=10),急性排异反应Ⅰa～Ⅰb级为B组(n=8),急性排异反应≥Ⅱ级为C... 详细信息

目的探讨超声心动图二维应变和应变率成像技术在监测心脏移植术后急性排异反应方面的价值。方法对25例心脏移植患者在活检12h内行超声心动图检查。急性排异反应0级为A组(n=10),急性排异反应Ⅰa～Ⅰb级为B组(n=8),急性排异反应≥Ⅱ级为C组(n=7)。正常对照组为D组(n=30)。应用二维应变和应变率成像测量收缩期各室壁纵向、径向及环向应变及应变率。对各数据进行组间比较,并进行统计学分析。结果二维应变应变率分析:A、B、C组与D组比较:室间隔基底段收缩期纵向应变、二尖瓣水平前间隔环向应变率、二尖瓣水平所有节段的径向应变均明显减低(p<0.05)。结论二维应变和应变率成像技术的径向应变能早期、敏感地反映出≥Ⅱ级心脏移植急性排异反应患者的心脏收缩功能变化,可以作为心脏移植术后急性排异反应的筛查指标。

关键词：超声心动描记术应变应变率心脏移植急性排异反应

In vivo and ex vivo confocal endomicroscopy of pancreatic cystic lesions: A prospective study

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World journal of Gastroenterology 2017年第18期23卷 3338-3348页

作者： Somashekar G Krishna Rohan M Modi Amrit K Kamboj Benjamin j Swanson phil A Hart Mary E Dillhoff Andrei Manilchuk Carl R Schmidt Darwin L Conwell Division of Gastroenterology Hepatology and NutritionThe Ohio State University Wexner Medical Center Department of Internal Medicine The Ohio State University Wexner Medical Center College of Medicine The Ohio State University Wexner Medical Center Department of pathology The Ohio State University Wexner Medical Center Division of Surgical Oncology The Ohio State University Wexner Medical Center Deparment of General Surgery The Ohio State University Wexner Medical Center

To investigate the reproducibility of the in vivo endoscopic ultrasound (EUS) - guided needle based confocal endomicroscopy (nCLE) image patterns in an ex vivo setting and compare these to surgical histopathology for characterizing pancreatic cystic lesions (pCLs).METHODSIn a prospective study evaluating EUS-nCLE for evaluation of pCLs, 10 subjects underwent an in vivo nCLE (AQ-Flex nCLE miniprobe; Cellvizio, MaunaKea, paris, France) during EUS and ex vivo probe based CLE (pCLE) of the pCL (Gastroflex ultrahigh definition probe, Cellvizio) after surgical resection. Biopsies were obtained from ex vivo CLE-imaged areas for comparative histopathology. All subjects received intravenous fluorescein prior to EUS and pancreatic surgery for in vivo and ex vivo CLE imaging *** total of 10 subjects (mean age 53 ± 12 years; 5 female) with a mean pCL size of 34.8 ± 14.3 mm were enrolled. Surgical histopathology confirmed 2 intraductal papillary mucinous neoplasms (IpMNs), 3 mucinous cystic neoplasms (MCNs), 2 cystic neuroendocrine tumors (cystic-NETs), 1 serous cystadenoma (SCA), and 2 squamous lined pCLs. Characteristic in vivo nCLE image patterns included papillary projections for IpMNs, horizon-type epithelial bands for MCNs, nests and trabeculae of cells for cystic-NETs, and a “fern pattern” of vascularity for SCA. Identical image patterns were observed during ex vivo pCLE imaging of the surgically resected pCLs. Both in vivo and ex vivo CLE imaging findings correlated with surgical *** vivo nCLE patterns are reproducible in ex vivo pCLE for all major neoplastic pCLs. These findings add further support the application of EUS-nCLE as an imaging biomarker in the diagnosis of pCLs.

关键词： Confocal laser endomicroscopy Serous cystadenoma pancreatic neuroendocrine tumor Intraductal papillary mucinous neoplasm pancreatic cystic neoplasm

经食管超声心动图检测主动脉粥样硬化斑块与冠状动脉病变严重程度的相关性研究

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中华超声影像学杂志 2009年第10期18卷 832-835页

作者：何怡华李治安谷孝艳 j.V.(Ian)nixon 首都医科大学附属北京安贞医院超声诊断科北京100029 pauley Heart Center Virginia Commonwealth UniversityUSA

目的通过经食管超声心动图检测主动脉的不同部位不同斑块性质与冠状动脉血管病变严重程度进行对比研究，寻找冠状动脉病变严重程度的预测因素。方法对118例同时进行了经食管超声心动图及冠状动脉造影检查的患者进行对比研究。冠状动脉... 详细信息

目的通过经食管超声心动图检测主动脉的不同部位不同斑块性质与冠状动脉血管病变严重程度进行对比研究，寻找冠状动脉病变严重程度的预测因素。方法对118例同时进行了经食管超声心动图及冠状动脉造影检查的患者进行对比研究。冠状动脉造影显示血管内径狭窄≥70％定义为冠状动脉病变。粥样硬化斑块厚度大于4mm，有漂浮物形成或斑块溃疡定义为复杂斑块；其他大于2mm并小于4mm的斑块定义为简单斑块。根据冠状动脉病变支数将研究对象分为4组：A组（0支病变）99例，B组（1支病变）31例，C组（2支病变）8例，D组（3支病变）30例，比较各组间粥样硬化斑块的发生部位及程度特征。结果与A组0支病变的99例相比，有血管狭窄的89例患者（包括B，C，D组）的主动脉内粥样斑块的发生率、严重度均明显增高（p〈0．05）。多元回归分析显示高血压（优势比3．0，95％可信区间1．3～7．0，p=0．013）、糖尿病（优势比2．4，95％可信区间1．1～4．9，p=0．022）及主动脉斑块（优势比3．8，95％可信区间1．8～8．2，p=0．001）与冠状动脉病变发生明显相关。简单及复杂斑块均与冠状动脉病变严重度明显相关（p〈0．001）。多元回归分析显示主动脉降部复杂斑块是冠状动脉病变的最强预测因子（优势比5．4，95％可信区间1．8～16．4，p=0．003）。结论主动脉内简单及复杂粥样斑块均与冠状动脉病变严重度明显相关。降主动脉复杂斑块是冠状动脉病变的最强预测因子。

关键词：超声心动描记术经食管主动脉动脉粥样硬化冠状动脉疾病

Genetic Analysis of ele Mutants and Comparative Mapping of ele1 Locus in the Control of Organ Internal Asymmetry in Garden pea

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journal of Integrative plant Biology 2010年第6期52卷 528-535页

作者： Xin Li Li-Li Zhuang Mike Ambrose M. phil. Catherine Rameau Xiao-He Hu jun Yana Da Luo School of Life Science and Biotechnology Shanghai JiaoTong University Shanghai 200030 China Department of Crop Genetics John Innes Centre Colney Norwich NR4 7UH United Kingdom Station de Genetique et d'Amelioration des plantes Institut J.P. Bourgin UR 254 INRA Versailles France National Key Laboratory of plant Molecular Genetics Institute of Plant Physiology and Ecology Shanghai Institutes for Biologica Sciences the Chinese Academy of Sciences Shanghai 200032 China

previous study has shown that during zygomorphic development in garden pea （pisum sativum L.）, the organ internal （IN） asymmetry of lateral and ventral petals was regulated by a genetic locus, SYMMETRIC pETAL 1 （SYp1）, while the dorsoventral （DV） asymmetry was determined by two CYC-like TCp genes or the psCYC genes, KEELED WINGS （K） and LOBED STANDARD 1 （LST1）. In this study, two novel loci, ELEpHANT EAR-LIKE LEAF 1 （ELE1） and ELE2 were characterized. These mutants exhibit a similar defect of IN asymmetry as syp1 in lateral and ventral petals, but also display pleiotropic effects of enlarged organ size. Genetic analysis showed that ELE1 and ELE2 were involved in same genetic pathway and the enlarged size of petals but not compound leaves in e/e2 was suppressed by introducing k and Ist1, indicating that the enlargement of dorsal petal in e/e2 requires the activities of K and LST1. An experimental framework of comparative genomic mapping approach was set up to map and clone LjELE1 locus in Lotus japonicus. Cloning the ELE1 gene will shed light on the underlying molecular mechanism during zygomorphic development and further provide the molecular basis for genetic improvement on legume crops.

关键词： Viverridae Genetics Organizations Corolla Loci

Quadratic convective flow of radiated nano-jeffrey liquid subject to multiple convective conditions and Cattaneo-Christov double diffusion

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Applied Mathematics and Mechanics(English Edition) 2018年第9期39卷 1311-1326页

作者： p.B.SAMpATH KUMAR B.MAHANTHESH B.j.GIREESHA S.A.SHEHZAD Department of Studies and Research in Mathematics Kuvempu University Department of Mathematics Christ University Department of Mathematics COMSATS Institute of Information Technology

A nonlinear flow of jeffrey liquid with Cattaneo-Christov heat flux is investigated in the presence of nanoparticles. The features of thermophoretic and Brownian movement are retained. The effects of nonlinear radiation, magnetohydrodynamic(MHD), and convective conditions are accounted. The conversion of governing equations into ordinary differential equations is prepared via stretching transformations. The consequent equations are solved using the Runge-Kutta-Fehlberg(RKF) method. Impacts of physical constraints on the liquid velocity, the temperature, and the nanoparticle volume fraction are analyzed through graphical illustrations. It is established that the velocity of the liquid and its associated boundary layer width increase with the mixed convection parameter and the Deborah number.

关键词： nonlinear convection jeffrey liquid nanoliquid convective condition thermophoretic Brownian motion

南极洲万达盐湖中的痕量金属——一个封闭湖盆中痕量金属垂直迁移模式

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中国科学（B辑） 1991年第10期 1100-1110页

作者：于昇松 W.j.Grenn p.A.nixon 中国科学院盐湖研究所西宁810008 美国俄亥俄州迈阿密大学

万达湖(Vanda Lake)位于南极洲赖特谷(Wright Valley),它是一典型的双季回水的CaCl_2型盐湖。本文基于该盐湖水溶液的某些化学和物理性质,阐述了湖水中的痕量金属Fe,Mn,pb,Cr,Cu,Co,Ni和Cd浓度随水深变化的垂直地球化学分布,讨论了湖水... 详细信息

万达湖(Vanda Lake)位于南极洲赖特谷(Wright Valley),它是一典型的双季回水的CaCl_2型盐湖。本文基于该盐湖水溶液的某些化学和物理性质,阐述了湖水中的痕量金属Fe,Mn,pb,Cr,Cu,Co,Ni和Cd浓度随水深变化的垂直地球化学分布,讨论了湖水中的这些痕量金属的垂直迁移作用,并试图建立一封闭的氯化物型盐湖水中痕量金属垂直迁移模式。

关键词：南极洲痕量金属离子活度积

Assessment of Molecular Signalling Mechanisms for Eosinophilia in Rottweilers

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Open journal of Veterinary Medicine 2012年第4期2卷 170-177页

作者： Nathalee prakash Michael j. Day phil Stumbles Iain R. peters Mellora Sharman Amanda paul Caroline Mansfield School of Veterinary and Biomedical Sciences Murdoch University Perth Australia School of Veterinary Sciences University of Bristol Bristol UK

Rottweilers are predisposed to eosinophilic diseases, including hypereosinophilic syndrome. The immunopathogenesis of idiopathic eosinophilia is poorly characterised in dogs and man. Studies in people have suggested cytokines, particularly interleukin (IL)-5, play a role in instigating and perpetuating eosinophilia. This study sought to establish whether differences in gene expression, and concentration of selected, cytokines and chemokines were associated with eosinophilia in Rottweilers. Quantitative real-time reverse transcriptase polymerase chain reaction (qRT-pCR) assays were used to quantify messenger ribonucleic acid (mRNA) encoding cytokines IL-4, -5, -10, -12p19, -12p35, -12p40, -18, interferon gamma (IFN-γ) and chemokines eotaxin-2 and -3 from peripheral blood mononuclear cell (pMBC) samples obtained from healthy dogs (breeds other than Rottweiler) with normal eosinophil blood counts (n = 5) and Rottweilers with normal (n = 6), mildly increased (n = 7) and high (n = 3) eosinophil blood counts. Quantification of plasma IFN-γ and IL-5 was performed using commercially available canine-specific enzyme-linked immunosorbent assays ELISAs. Cytokine mRNA was measurable in all samples, although eotaxin-2 and -3 were not detected. No significant differences in gene expression of any cytokine were found between groups (based on eosinophil count or breed). No significant difference in plasma IL-5 or IFN-γ concentration was present between groups. In conclusion, there were no significant differences in cytokine mRNA profiles or plasma IL-5 and IFN-γ levels between Rottweilers with increased eosinophil counts and Rottweiler and non-Rottweiler dogs with normal eosinophil counts.

关键词： Cytokines Dogs IL-5 IFN-γ Hypereosinophilic Syndrome

Increased type III interferons and NK cell functions in SARS-CoV-2-infected children

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Signal Transduction and Targeted Therapy 2023年第3期8卷 888-890页

作者： Seong Dong jeong Hoyoung Lee ju Young Chang Seong Yong Lee ji Eun Choi Eunmi Yang Hye Won jeong jae-phil Choi Mi Seon Han Eui-Cheol Shin The Center for Viral Immunology Korea Virus Research InstituteInstitute for Basic Science(IBS)Daejeon 34126Republic of Korea Department of pediatrics Seoul Metropolitan Government-Seoul National University Boramae Medical Center and Seoul National University of College of MedicineSeoul 07061Republic of Korea Division of infectious diseases Seoul Medical CenterSeoul 02053Republic of Korea Department of Internal Medicine Chungbuk National University College of MedicineCheongju 28644Republic of Korea Graduate School of Medical Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea

Dear Editor,Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection is more likely to progress to severe disease in the elderly,and the rates of hospitalization for coronavirus disease 2019(COVID-19)increase with age.1,2 Herein,we comprehensively compared adaptive and innate immune responses between children and adults infected with SARS-CoV-2.

关键词： infected acute respiratory