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Handgrip strength and health outcomes: Umbrella review of systematic reviews with meta-analyses of observational studies

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Journal of Sport and Health Science 2021年第3期10卷 290-295页

作者： Pinar Soysal Christopher Hurst Jacopo Demurtas Joseph Firth Reuben Howden Lin Yang Mark A.Tully Ai Koyanagi petre cristia. ilie Guillermo F.Lopez-Sanchez Lukas Schwingshackl Nicola Veronese Lee Smith Department of Geriatric Medicine Bezmialem Vakif UniversityIstanbul 34093Turkey Institute of Neuroscience Newcastle UniversityNewcastle upon Tyne NE17RUUK Primary Care Department Azienda Usl Toscana Sud EstGrosseto 52100Italy Division of Psychology and Mental Health University of ManchesterManchester M139PLUK College of Health&Human Services University of North Carolina at CharlotteLong BeachCA 90815USA Department of Cancer Epidemiology and Prevention Research Alberta Health ServicesHoly Cross CentreAlbertaT5J 3E4Canada School of Health Sciences Institute of Mental Health SciencesUlster UniversityNewtownabbey BT151EDUK Research and Development Unit Sant Joan de Deu Health ParkCIBER of Mental Health(CIBERSAM)Barcelona 08003Spain ICREA Pg.Lluis Companys 23Barcelona 08010Spain The Queen Elizabeth Hospital King’s Lynn NHS Foundation Trust King’s Lynn PE304ETUK Faculty of Sport Sciences University of MurciaMurcia 30100Spain Institute for Evidence in Medicine Medical CenterUniversity of FreiburgFaculty of MedicineUniversity of FreiburgFreiburg 79085Germany Neuroscience Institute Aging BranchNational Research CouncilPadua 35122Italy The Cambridge Centre for Sport and Exercise Sciences Anglia Ruskin UniversityCambridge CB11PTUK

Purpose:The aim of the present study was to assess both the credibility and strength of evidence arising from systematic reviews with meta-analyses of observational studies on handgrip strength and health ***:An umbrella review of systematic reviews with meta-analyses of observational studies was *** assessed meta-analyses of observational studies based on random-effect summary effect sizes and their p values,95%prediction intervals,heterogeneity,small-study effects,and excess *** graded the evidence from convincing(Class I)to weak(Class IV).Results:From 504 articles returned in a search of the literature,8 systematic reviews were included in our review,with a total of 11 ***,nine of the 11 of the outcomes reported nominally significant summary results(p<0.05),with 4 associations surviving the application of the more stringent p value(p<106).No outcome presented convincing *** associations showed Class II evidence(i.e.,highly suggestive):(1)higher handgrip values at baseline were associated with a minor reduction in mortality risk in the general population(n=34 studies;sample size=1,855,817;relative risk=0.72,95%confidence interval(95%CI):0.670.78),(2)cardiovascular death risk in mixed populations(n=15 studies;relative risk=0.84,95%CI:0.780.91),and(3)incidence of disability(n=7 studies;relative risk=0.76,95%CI:0.660.87).Conclusion:The present results show that handgrip strength is a useful indicator for general health status and specifically for early all-cause and cardiovascular mortality,as well as *** further inform intervention strategies,future research is now required to fully understand mechanisms linking handgrip strength scores to these health outcomes.

关键词： Handgrip strength Health outcomes Meta-analysis Umbrella review

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