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Journal of Arid Land 2023年第4期15卷 407-423页

作者： Sarra HECHMI Samira MELKI Mohamed-Naceur KHELIL rim GHRIB Moncef GUEDDARI Naceur JEDIDI Water Research and Technology Center University of CarthageSoliman 8020Tunisia National Institute for Research in Rural Engineering Water and ForestryAriana 2080Tunisia Faculty of Sciences of Tunis University of Tunis El ManarTunis 2092Tunisia

In Tunisia,water scarcity is only adding pressure on water demand in *** the context of sustainable development goals,Tunisia has been reusing treated wastewater(TWW)as a renewable and inexpensive source for soil fertigation and groundwater(GW)***,major risks can be expected when the irrigation water is of poor *** study aims for evaluating the potential risk of TWW and GW irrigation on soil ***,we evaluated the suitability of water quality through the analysis of major and minor cations and anions,metallic trace elements(MTEs),and the sodium hazard by using the sodium adsorption ratio(SAR)and the soluble sodium percentage(SSP).The risk of soil sodicity was further assessed by SAR and the exchangeable sodium percentage(ESP).The degree of soil pollution caused by MTEs accumulation was evaluated using geoaccumulation index(Igeo)and pollution load index(PLI).Soil maps were generated using inverse spline interpolation in ArcGIS *** results show that both water samples(i.e.,TWW and GW)are suitable for soil irrigation in terms of salinity(electrical conductivity5.00),followed by Ni^(2+)and Pb^(2+).Nevertheless,Cd^(2+)presents the lowest risk of soil pollution(Igeo50.0%).This study shows that the use of imagery tools,such as ArcGIS,can

关键词： treated wastewater metallic trace elements(MTEs) pollution indices sodium adsorption ratio(SAR) geoaccumulation index(Igeo) Tunisia

Overview of Activities:ARES-III and LEARN Analog Missions in the LunAres Hab

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Space(Science & Technology) 2022年第1期2022卷 64-82页

作者： Simon Bouriat Matej Poliaček Jacob Smith SpaceAble France Aerospace Industry Professional and Independent Reseacher Slovakia UK Students for the Exploration and Development of Space(UKSEDS) UK

Progress is being made on human Lunar and Martian missions by space agencies and private organisations around the world,with the aims of establishing reliable long-duration *** this,research is being carried out under controlled and isolated conditions within simulated space habitats,to gain insights into the effects of such conditions on the research subjects and their impacts on crews’wellbeing and *** paper provides an overview of the experiments conducted during two separate 15-day missions—one Martian and one Lunar—conducted in the LunAres Research Base in Piła,Poland,in *** activities were common between the two crews;others were only carried out by *** the same methodology,both collected cognitive function,environmental,physiological,and inventory data,resulting in a larger dataset allowing comparisons between the two missions in terms of varying human *** conducted by the Lunar crew included the following:effects of consuming lyophilised food on oral health and saliva production,influence of isolation on hearing capability,feelings on security in the isolated habitat,and research into earthworm growth in different soil *** Mars mission analysed physical performances of the crew and compared them to performances realised during similar activities in Mars Research Desert Station missions and the impact of confinement on their efficiency performing a remote operation of a *** each piece of research,an overview of the background,methodology,results,and conclusions is given,referencing the resulting *** addition,nonresearch activities are included for completeness and context.

关键词： Desert habitat consuming

Curing Kinetics of Tannin and Lignin Biobased Adhesives Determined by DSC and ABES

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Journal of Renewable Materials 2022年第8期10卷 2117-2131页

作者： Jaša Saražin Ida Poljanšek Antonio Pizzi MilanŠernek University of Ljubljana Biotechnical FacultyLjubljana1000Slovenia Universitéde Lorraine LERMAB-ENSTIB Epinal88000France

The curing process of two biobased adhesives:pine tanninhexamine(TH)and organosolv lignin non-isocyanate polyurethane(NIPU),suitable for interior nonstructural use,were compared with commercial urea-formaldehyde(UF)*** in chemical structure before and after the curing process were observed with Fouriertransform infrared spectroscopy(FTIR).The process of adhesive curing was monitored with differential scanning calorimetry(DSC)and the automated bonding evaluation system(ABES).Both DSC and ABES measurements confirmed UF as the fastest and NIPU as the slowest curing adhesive *** into account the ABES results,the optimal pressing parameters for the TH adhesive would be 4 min at 175℃,for the NIPU adhesive 7 min at 200℃and for the UF 1.5 min at 100℃.Strong linear correlation was observed between mechanical and chemical curing for the UF and NIPU adhesives,whereas lower correlation was observed for the TH *** all observed adhesives,the DSC measurements were underestimating the curing process determined by ABES in the first part and overestimating it at the *** underestimation was the most evident with the TH adhesive and the less with the UF *** comparing the uncured and cured FTIR spectra of all three types of adhesives,a drastic decrease in the characteristic band of-OH groups at 3330–3400 cm^(−1)and an increase in the signal intensity at 2920 cm^(−1)of aliphatic-CH2-groups were *** the UF adhesive,the C=O stretching frequency has shifted from 1632 cm^(−1)for uncured to three different bands at 1766,1701,and 1655 cm^(−1)for cured *** sharp band for phenolic alcohols at 1236 cm^(−1)of C–O stretch and hydroxyl O–H functional group at 1009 cm^(−1)and at 684 cm^(−1)of uncured TH adhesive diminished during curing,which indicates that a crosslinking reaction occurs via-OH *** peak of the C=O group of urethane bridges at 1697 cm^(−1)for uncured NIPU shifted to lower wavenumber at 1633 cm^(−1)for cured NIPU.

关键词： Biobased adhesives curing kinetics tannin lignin ABES DSC FTIR

Prospective study of MMP7 serum levels in the diagnosis of cholangiocarcinoma

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World Journal of Gastroenterology 2010年第37期16卷 4697-4703页

作者： Kawin Leelawat Siriluck Narong Jerasak Wannaprasert Thawee Ratanashu-ek Department of Surgery Rajavithi Hospital College of Medicine Department of Surgery Rangsit University

AIM: To determine whether the serum level of matrix metalloproteinase-7 (MMP7) has the potential to diagnosis cholangiocarcinoma from benign biliary tract diseases. METHODS: This study was performed according to the PRoBE (a prospective-specimen-collection, retrospectiveblinded-evaluation) design. A total of 187 patients with obstructive jaundice were consecutively enrolled. After the diagnostic status of these patients was ascertained, their levels of serum MMP7 were assayed and compared with serum carbohydrate antigen 19-9 (CA19-9). This was conducted in a blinded case (cholangiocarcinoma)control (benign biliary tract disease) setup. RESULTS: MMP7 and CA19-9 serum levels were significantly elevated in cholangiocarcinoma patients (P < 0.001). The area under the curve (AUC) from a receiver operating characteristic (ROC) curve analysis for thediagnosis of cholangiocarcinoma, using MMP7 was more accurate than CA19-9 (AUC = 0.84, 95% CI: 0.778-0.903 for MMP7 and AUC = 0.79, 95% CI: 0.708-0.868 for CA19-9). The sensitivity and specificity of serum MMP7 (cut-off value of 5.5 ng/mL) was 75% and 78%, respectively, while the sensitivity and specificity of serum CA19-9 (cut-off value of 100 U/mL) was 68% and 87%, respectively. CONCLUSION: Serum values of MMP7 and CA19-9 appear to be useful biomarkers for differentiating cholangiocarcinoma from benign biliary tract obstructive diseases.

关键词： Carbohydrate antigen 19-9 Cholangiocarcinoma Matrix metalloproteinase-7 Sensitivity Specificity Tumor marker

Endophytic fungi alter sucking bug responses to cotton reproductive structures

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Insect Science 2017年第6期24卷 1003-1014页

作者： Gregory A. Sword Ashley Tessnow Maria Julissa ek-Ramos Department of Entomology Texas A&M University College Station Texas USA Ecology and Evolutionary Biology Interdisciplinary Program Texas A&M University College Station Texas USA Laboratorio de Inmunologia y Virologia Facultad de Ciencias BiolSgicas Universidad Autonoma de Nuevo Leon San Nicolas de los Garza Nuevo Leon Mexico

All plants including cotton host a wide range of microorganisms as endophytes. There is a growing appreciation of the prevalence, ecological significance and management potential of facultative fungal endophytes in protecting plants from pests, pathogens and environmental stressors. Hemipteran sucking bugs have emerged as major pests across the U.S. cotton belt, reducing yields directly by feeding on developing reproductive structures and indirectly by vectoring plant pathogens. We used no-choice and simultaneous choice assays to examine the host selection behavior of western tarnished plant bugs （Lygus hesperus） and southern green stink bugs （Nezara viridula） in response to developing flower buds and fruits from cotton plants colonized by 1 of 2 candidate beneficial fungal endophytes, Phialemonium inflatum or Beauveria bassiana. Both insect species exhibited strong negative responses to flower buds （L. hesperus） and fruits （N. viridula） from plants that had been colonized by candidate endophytic fungi relative to control plants under both no-choice and choice conditions. Behavioral responses of both species indicated that the insects were deterred prior to contact with plant tissues from endophyte-colonized plants, suggesting a putative role for volatile compounds in mediating the negative response. Our results highlight the role of fungal endophytes as plant mutualists that can have positive effects on plant resistance to pests.

关键词： behavior endophyte fungi Hemiptera mutualism sucking bug

Molecular biology of pancreatic cancer

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World Journal of Gastroenterology 2011年第24期17卷 2897-2908页

作者： Miroslav Zavoral petra Minarikova Filip Zavada Cyril Salek Marek Minarik Charles University 1st Medical FacultyInternal Clinic Institute of hematology and blood transfusion Center for Applied Genomics of Solid Tumors(CEGES) Genomac International

In spite of continuous research efforts directed at early detection and treatment of pancreatic cancer, the outlook for patients affected by the disease remains dismal. With most cases still being diagnosed at advanced stages, no improvement in survival prognosis is achieved with current diagnostic imaging approaches. In the absence of a dominant precancerous condition, several risk factors have been identified including family history, chronic pancreatitis, smoking, diabetes mellitus, as well as certain genetic disorders such as hereditary pancreatitis, cystic fibrosis, familial atypical multiple mole melanoma, and Peutz-Jeghers and Lynch syn- dromes. Most pancreatic carcinomas, however, remain sporadic. Current progress in experimental molecular techniques has enabled detailed understanding of the molecular processes of pancreatic cancer development. According to the latest information, malignant pancre- atic transformation involves multiple oncogenes and tumor-suppressor genes that are involved in a variety of signaling pathways. The most characteristic aberrations （somatic point mutations and allelic losses） affect onco- genes and tumor-suppressor genes within RAS, AK-I- and Wnt signaling, and have a key role in transcription and proliferation, as well as systems that regulate the cell cycle （SMAD/DPC, CDKN2A/p16） and apoptosis （TP53）. Understanding of the underlying molecular mechanisms should promote development of new methodology for early diagnosis and facilitate improvement in current approaches for pancreatic cancer treatment.

关键词： Pancreatic cancer Risk factors Molecularbiology Pancreatitis Diabetes

Regulatory Micro RNA Networks:Complex Patterns of Target Pathways for Disease-related and Housekeeping MicroRNAs

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Genomics, Proteomics & Bioinformatics 2015年第3期13卷 159-168页

作者： Sachli Zafari Christina Backes petra Leidinger Eckart Meese Andreas Keller Chair for Clinical Bioinformatics Saarland UniversityUniversity Hospital Department of Human Genetics Saarland UniversityUniversity Hospital

Blood-based mieroRNA （miRNA） signatures as biomarkers have been reported for various pathologies, including cancer, neurological disorders, cardiovascular diseases, and also infections. The regulatory mechanism behind respective miRNA patterns is only partially understood. Moreover, ＂preserved＂ miRNAs, i.e., miRNAs that are not dysregulated in any disease, and their biological impact have been explored to a very limited extent. We set out to systematically determine their role in regulatory networks by defining groups of highly-dysregulated miRNAs that contribute to a disease signature as opposed to preserved housekeeping miRNAs. We further determined preferential targets and pathways of both dysregulated and preserved miRNAs by computing multi-layer networks, which were compared between housekeeping and dysregulated miRNAs. Of 848 miRNAs examined across 1049 blood samples, 8 potential housekeepers showed very limited expression variations, while 20 miRNAs showed highly-dysregulated expression throughout the investigated blood samples. Our approach provides important insights into miRNAs and their role in regulatory networks. The methodology can be applied to systematically investigate the differences in target genes and pathways of arbitrary miRNA sets.

关键词： miRNA miRNA targeting Systems biology Regulatory networks miRNA housekeepers

Effect of Roasting Temperature on Production of Functional Wild-Rice Tea and Factors Influencing Purchase Intention Towards Wild-Rice Tea

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Rice science 2022年第3期29卷 197-200页

作者： Hyun Yi JUNG Kyoung rim HAN Geon LEE Joong Kyun KIM Department of Biotechnology and Bioengineering Pukyong National UniversityNam-GuBusan 485137Republic of Korea Department of Research&Development Hyundae F&CBusan 604-842Republic of Korea Department of Environmental Engineering Dong-A UniversityBusan 49315Republic of Korea

The properties of raw wild rice were investigated to produce a functional tea,and the value of this tea was *** highest antioxidant activity[80.5%2,2-diphenyl-1-picrylhydrazyl(DPPH)radical scavenging activity]was achi... 详细信息

关键词： Influencing Tea Functional

Numerical Simulation of Separated Flows in Channels

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Journal of Thermal Science 2012年第2期21卷 145-153页

作者： Petr Louda Jaromír Príhoda Petr Sváek Karel Kozel Czech Technical University in Prague Fac. of Mechanical Engineering Karlovo nám. 13 CZ-121 35 Praha 2 Institute of Thermomechanics AS CR v.v.i. Dolejkova 5 CZ-182 00 Praha 8

The work deals with numerical modelling of turbulent flows in channels with an expansion of the cross-section where flow separation and reattachment occur. The performance of several eddy viscosity models and an explicit algebraic Reynolds stress model (EARSM) is studied. The used test cases are flows in channels with various backward facing steps where the step is perpendicular or inclined and the top wall is parallel or deflected. Furthermore, a channel with the circular ramp is considered. The numerical solution is achieved by the finite volume method or by the finite element method. The results of both numerical approaches are compared.

关键词： backward facing step flow EARSM model SST model

Microstructure, Mechanical Properties and Wear Behaviourof Deep-Cryogenic-Treated HSS

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材料热处理学报 2004年第5期25卷 540-545页

作者： V. Leskovek M. Kalin J. Vi■intin Institute of Metals and Technology Ljubljana SloveniaUniversity of Ljubljana Center for Tribology and Technical Diagnostics Ljubljana SloveniaUniversity of Ljubljana Center for Tribology and Technical Diagnostics Ljubljana Slovenia

In this paper we compare the wear behaviour of a vacuum-heat-treated ESR AISI M2 high-speed steel and the same steel that was vacuum heat treated in conjunction with a deep-cryogenic treatment at -196 °C. Four different tempering temperatures for the specimens austenized at the same austenitizing temperature were carefully selected to obtain various in-advance-determined combinations of the microstructures, the fracture toughness, KIc and the Rockwell-C hardness. Each of the eight specimens was therefore characterised by these microstructures and resulting material properties. The wear study was performed using a reciprocating sliding device under well-controlled contact conditions. Relatively high loads were used to provide enough wear for a comparison of the selected samples. A much harder and dissimilar model counter-material, i.e. silicon nitride ceramic, was used in order to avoid excessive wear of the counter samples and adhesion, which could occur in contacts with similar materials (metals/steels) under such high loads and in non-lubricated conditions. The wear behaviours were then compared and discussed in terms of these microstructures and the related properties. The differences in the wear resistance obtained in our investigation were as high as an order of magnitude. However, the beneficial effects are not a direct result of the type of the treatment, but relate to a proper combination of the resulting fracture toughness and the hardness. The more uniform and moderate values, which, however, tend to be obtained with a deep-cryogenic treatment, are beneficial to the high wear resistance of the selected high-speed steel.

关键词：高速钢显微结构深低温处理机械性质磨损性能