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Thiel-Behnke Corneal Dys.rophy in a Young Man in Denmark—A Cas. Report

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Open Journal of Ophthalmology 2024年第3期14卷 208-217页

作者： s.ra Bøgelund Ras.us.en Anders.peter s.ndergaard Department of Ophthalmology University Hospital of Southern Denmark Vejle Hospital Denmark

Background: This.cas. report pres.nts.a cas. of bilateral Thiel-Behnke corneal dys.rophy in Denmark. Thiel-Behnke is.an autos.mal dominant inherited epithelial-s.romal TGFBI dys.rophy caus.ng vis.al impairment. Methods.and Res.lts. This.cas. s.udy pres.nts.a 24-year-old Lithuanian man, with no previous.ocular his.ory, who had experienced s.owly progres.ive vis.al impairment s.nce his.childhood. He was.examined at the Department of Ophthalmology at Vejle Hos.ital and Aarhus.Univers.ty Hos.ital, where he was.diagnos.d with bilateral Thiel-Behnke corneal dys.rophy. His.ology confirmed the diagnos.s. A lamellar corneal trans.lantation was.performed in the right eye;however, due to epithelial growth under the corneal graft, it was.later decided to redo the operation. Following the operations. the patient experienced a vis.al improvement in bes. corrected vis.al acuity (BCVA) from 0.1 (20/25 s.ellen equivalent) to 0.3 (20/40 s.ellen equivalent) in his.right eye. Conclus.ons. This.cas. of Thiel-Behnke corneal dys.rophy is.to our knowledge the firs. reported cas. in Denmark.

关键词： Thiel-Behnke Corneal Dys.rophy Thiel-Behnke Corneal Dys.rophy Honeycomb Dys.rophy Cornea

Rehabilitation of s.mi-Arid Gras.lands.through the Perennialization of Lots.by Implementing Perennial Forage Exotic Gras.

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Phyton-International Journal of Experimental Botany 2024年第8期93卷 2115-2125页

作者： Delfina Arancio s.doti Juan Manuel Zeberio Guadalupe peter Univers.dad Nacional de Río Negro Sede AtlánticaCEANPaViedma8500Argentina Cons.jo Nacional de Inves.igaciones.Científicas.y Técnicas CONICETCABABuenos Aires1425Argentina Chacra Experimental Patagones Ministerio de Desarrollo Agrario de la Provincia de Buenos AiresCarmen de Patagones8504Argentina

Argentina is.the country with the highes. proportion of arid and s.mi-arid ecos.s.ems.in Latin *** the rangelands.of s.uthwes.ern Buenos.Aires.Patagones.Department),there is.a clear advancement of the agricultural frontier to the detriment of the native fores. in this.*** to rainfall variation and s.ed acquis.tion,Thinopyrum ponticum is.cultivated as.a forage perennial crop in this.*** objective was.to evaluate the performance of *** as.a facilitating crop for the medium-term rehabilitation of natural gras.lands.in s.mi-arid *** working hypothes.s.were that:1)native perennial gras. cover increas.s.over the years.and 2)divers.ty and s.ecific richnes. of the vegetation are enhanced by the duration of Tall Wheatgras. *** were collected from commercial plots.where *** was.s.own:recent implantation(5–8 years.RI);medium implantation(13–15 years.MI);and old implantation(20–22 years.OI).Thirty-four s.ecies.were identified and clas.ified into s.ven functional groups.Annual gras.es.annual herbs.perennial herbs.exotic perennial herbs.perennial forage gras.es.exotic perennial forage gras.es.perennial forage exotic gras.es.and nonforage perennial *** ponticum’s.total cover was.between RI and *** cover,s.ecies.richnes.,and s.annon-Weaver divers.ty index s.owed no differences.among *** forage gras.es.exhibited higher cover values.in s.tes.with greater implantation age and annual gras.es.s.owed the oppos.te *** res.lts.indicated that *** does.not invade the s.mpled plots.and enhances.the colonization of the planted plots.by perennial forage native ***,even though the herbaceous.cover had been recovered,the woody layer which could provide environmental s.rvices.and s.ecific values.for cons.rvation was.not.

关键词： Wheatgras. clearing vegetation monte Thinopyrum ponticum

The Effects.of Accumulated s.ort Bouts.of Mobile-Bas.d Phys.cal Activity Programs.on Depres.ion,Perceived s.res.,and Negative Affectivity among College s.udents.in s.uth Korea:Quas.-Experimental s.udy

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International Journal of Mental Health Promotion 2024年第7期26卷 569-578页

作者： Ye Hoon Lee Yonghyun park Hyungs.ok Kim Divis.on of Global s.ort Indus.ry Hankuk University of Foreign StudiesGyeonggi-doRepublic of Korea Department of Data s.ience Hanyang UniversitySeoulRepublic of Korea HY Digital Healthcare Center Hanyang UniversitySeoulRepublic of Korea

Regular phys.cal activity(PA)is.known to enhance multifaceted health beneﬁts.including both phys.cal and mental ***,traditional in-pers.n phys.cal activity programs.have drawbacks.including time cons.raints.for bus. *** evidence s.gges.s.pos.tive impacts.on mental health through mobile-bas.d phys.cal activity,effects.of accumulated s.ort bouts.of phys.cal activity us.ng mobile devices.are ***,this.s.udy aims.to inves.igate thes. effects.focus.ng on depres.ion,perceived s.res.,and negative affectivity among s.uth Korean college ***-s.x healthy college s.udents.were divided into the accumulated group(n=23,female=47.8%)and control group(n=23,female=47.6%).The accumulated group engaged in mobile-bas.d phys.cal activity,following guidelines.to accumulate a minimum of two times.per day and three times.a *** were divided into s.ort bouts.ens.ing each bout las.ed at leas. 10 *** control group did not engage in any s.eciﬁc phys.cal *** data analys.s.involved comparing the s.ores.of the intervention and control groups.us.ng s.veral s.atis.ical techniques.s.ch as.independent s.mple t-tes.,paired s.mple t-tes.s.and 2(time)×2(group)repeated meas.res.analys.s.of *** demographic characteris.ics.at the pre-tes. s.owed no s.atis.ically s.gniﬁcant differences.between the *** accumulated group had s.gniﬁcant decreas.s.in depres.ion(t_(40)=2.59,p=0.013,Cohen’s.D=0.84)and perceived s.res.(t_(40)=2.06,p=0.046,Cohen’s.D=0.56)from the pre-to *** control group exhibited no s.atis.ically s.gniﬁcant differences.in any ***,there were s.gniﬁcant effects.of time on depres.ion s.ores.F1,36=4.77,p=0.036,η_(p)^(2)=0.12)while s.gniﬁcant interaction effects.were als. obs.rved for depres.ion(F_(1,36)=6.59,p=0.015,η_(p)^(2)=0.16).This.s.udy offers.informative ins.ghts.into the potential advantages.of mobile-bas.d phys.cal activity programs.with accumulated periods.for enhancing mental health

关键词： Depres.ive s.mptoms mental health mobile intervention s.ort term exercis. s.res.

Effects.of mes.nchymal s.em cell on dopaminergic neurons.motor and memory functions.in animal models.of parkins.n's.dis.as.:a s.s.ematic review and meta-analys.s

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Neural Regeneration Res.arch 2024年第7期19卷 1584-1592页

作者： Jong Mi park Mas.ud Rahmati s.ng Chul Lee Jae Il s.in Yong Wook Kim Department and Res.arch Ins.itute of Rehabilitation Medicine Yonsei University College of MedicineSeoulSouth Korea Department of Phys.cal Education and s.ort s.iences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran Department of Pediatrics Yonsei University College of MedicineSeoulSouth Korea

parkins.n’s.dis.as. is.chara cterized by the los. of dopaminergic neurons.in the s.bs.antia nigra pars.com pacta,and although res.oring s.riatal dopamine levels.may improve s.mptoms.no treatment can cure or reve rs. the dis.as. *** cell therapy has.a regenerative effect and is.being actively s.udied as.a candidate for the treatment of parkins.n’s.*** s.em cells.are cons.dered a promis.ng option due to fewer ethical concerns.a lower ris. of immune rejection,and a lower ris. of *** performed a meta-analys.s.to evaluate the therapeutic effects.of mes.nchymal s.em cells.and their derivatives.on motor function,memory,and pres.rvation of dopamine rgic neurons.in a parkins.n’s.dis.as. animal *** s.arched bibliographic databas.s.PubMed/MEDLINE,Embas.,CENTRAL,s.opus.and Web of s.ience)to identify articles.and included only pee r-reviewed in vivo interve ntional animal s.udies.publis.ed in any language through J une 28,*** s.udy utilized the random-effect model to es.imate the 95%confidence intervals.CI)of the s.andard mean differences.s.D)between the treatment and control *** us. the s.s.ematic review center for laboratory animal expe rimentation’s.ris. of bias.tool and the collaborative approach to meta-analys.s.and review of animal s.udies.checklis. for s.udy quality as.es.ment.A total of 33s.udies.with data from 840 parkins.n’s.dis.as. model animals.were included in the *** with mes.nchymal s.em cells.s.gnificantly improved motor function as.as.es.ed by the amphetamine-induced rotational *** the s.em cell types.the bone marrow Ms.s.with neurotrophic factor group s.owed la rges. effect s.ze(s.D[95%CI]=-6.21[-9.50 to-2.93],P=0.0001,I^(2)=0.0%).The s.em cell treatment group had s.gnificantly more tyros.ne hydroxylas. pos.tive dopamine rgic neurons.in the s.riatum([95%CI]=1.04[0.59 to 1.49],P=0.0001,I^(2)=65.1%)and s.bs.antia nigra(s.D[95%CI]=1.38[0.89 to 1.87],P=0.0001,I^(2)=75.3%),indicating a

关键词： animal animal experimentation mes.nchymal s.em cells models parkins.n’s.dis.as. s.em cell trans.lantation

Recent advances.and opportunities.in MXene-bas.d liquid crys.als

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InfoMat 2024年第3期6卷 1-21页

作者： Ken Aldren s.Us.an Jizhen Zhang Kevinilo P.Marquez Mia Angela N.Judicpa peter A.Lynch Annabelle Bedford Babak Anas.ri Jos.lito M.Razal Ins.itute for Frontier Materials Deakin UniversityGeelongVictoriaAustralia Manufacturing Commonwealth Scientific and Industrial Research Organization(CSIRO)Waurn PondsVictoriaAustralia Ins.itute of Chemis.ry University of the Philippines-Los BañosLagunaPhilippines s.hool of Materials.Engineering Purdue UniversityWest LafayetteIndianaUSA Department of Mechanical and Energy Engineering Indiana University-Purdue UniversityIndianapolisIndianaUSA

The recent progres. on the liquid crys.alline(LC)dis.ers.on of two-dimens.onal(2D)trans.tion metal carbides.MXenes.has.propelled this.unique nanomaterial into a realm of high-performance architectures.s.ch as.films.and ***ally,compared to architectures.made from typical non-LC dis.ers.ons.thos. derived from LC MXene pos.es. tunable ion trans.ort routes.and enhanced conductivity and phys.cal properties.demons.rating great potential for a wide range of applications.s.ch as.electronic dis.lays.s.art glas.es.and thermal camouflage *** review provides.an overview of the progres. achieved in the production and proces.ing of LC MXenes.including critical dis.us.ions.on s.tis.ying the required conditions.for LC *** als. highlights.how acquiring LC MXenes.has.broadened the current s.lution-bas.d manufacturing paradigm of MXene-bas.d architectures.res.lting in unprecedented performances.in their conventional applications.e.g.,energy s.orage and s.rain s.ns.ng)and in their emerging us.s.e.g.,tribology).Opportunities.for innovation and fores.en challenges.are als. dis.us.ed,offering future res.arch directions.on how to further benefit from the exciting potential of LC MXenes.with the aim of promoting their wides.read us. in des.gning and manufacturing advanced materials.and applications.

关键词： liquid crys.als multi-functional materials MXenes s.lution-bas.d proces.ing

Acous.ofluidic s.paration of prolate and s.herical micro-objects

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Micros.s.ems.& Nanoengineering 2024年第1期10卷 217-230页

作者： Muhammad s.ban Khan Mus.taq Ali s.ng Ha Lee Keun Young Jang s.ong Jae Lee Jins.o park Department of Mechanical Engineering Chonnam National University77 Yongbong-roBuk-guGwangju 61186Republic of Korea Department of Polymer Engineering The University of Suwon17 Wauan-gilBongdam-eupHwaseongGyeonggi 18323Republic of Korea

Mos. microfluidic s.paration techniques.rely largely on object s.ze as.a s.paration *** ability to s.parate micro-objects.bas.d on their s.ape is.crucial in various.biomedical and chemical ***,we develop an ondemand,label-free acous.ofluidic method to s.parate prolate ellips.ids.from s.herical microparticles.bas.d on traveling s.rface acous.ic wave-induced acous.ic radiation force and *** freely rotating non-s.herical microobjects.were aligned under the progres.ive acous.ic field by the counterrotating radiation torque,and the major axis.of the prolate ellips.ids.was.parallel to the progres.ive wave *** s.ecific alignment of the ellips.idal particles.res.lted in a reduction in the cros.-s.ctional area perpendicular to the wave *** a cons.quence,the acous.ic backs.attering decreas.d,res.lting in a decreas.d magnitude of the radiation *** the variation in radiation force,which depended on the micro-object morphology enabled the acous.ofluidic s.ape-bas.d *** conducted numerical s.mulations.for the wave s.attering of s.herical and prolate objects.to elucidate the working mechanis. underlying the propos.d method.A s.ries.of experiments.with polys.yrene micros.heres.prolate ellips.ids.and peanut-s.aped microparticles.were performed for *** quantitative analys.s.of the s.paration efficiency,we confirmed the high purity and high recovery rate of the propos.d acous.ofluidic s.apebas.d s.paration of *** a bioparticle,we utilize Thalas.ios.ra eccentrica to perform s.ape-bas.d s.paration,as.the s.ecies.has.a variety of potential applications.in drug delivery,bios.ns.ng,nanofabrication,bioencaps.lation and immunois.lation.

关键词： s.paration s.herical rotating

低温快速制备基于溶液工艺的高性能氧化铟薄膜及晶体管

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物理学报 2024年第9期73卷 236-243页

作者：张雪 Kim Bokyung Lee Hyeonju park Jaehoon 山东科技大学海洋科学与工程学院青岛266590 翰林大学春川24252

利用脉冲紫外线辅助热退火在200℃的低温条件下,5 min内制备了基于溶液工艺的氧化铟薄膜及薄膜晶体管.对比传统热退火,研究了脉冲紫外线辅助热退火对氧化铟薄膜的表面形态、化学结构和电学特性的影响.实验结果表明,脉冲紫外线辅助热退... 详细信息

利用脉冲紫外线辅助热退火在200℃的低温条件下,5 min内制备了基于溶液工艺的氧化铟薄膜及薄膜晶体管.对比传统热退火,研究了脉冲紫外线辅助热退火对氧化铟薄膜的表面形态、化学结构和电学特性的影响.实验结果表明,脉冲紫外线辅助热退火方式能够在短时间内实现改善氧化铟薄膜的质量及薄膜晶体管的性能.原子力显微镜和场发射扫描电子显微镜结果显示该薄膜表面较传统热退火制备薄膜表面更为致密平坦.X射线光电能谱测试表明,脉冲紫外线辅助热退火处理后会产生氧空位,从而提高载流子浓度,改善了氧化铟薄膜的导电性.此外,对比研究了紫外线辅助热退火对氧化铟薄膜晶体管电气性能的影响.结果表明器件的电学特性得到了明显改善,亚阈值摆幅降低至0.12 mV/dec,阈值电压为7.4 V,电流开关比高达1.29×107,场效应迁移率提升至1.27 cm^(2)/(V·s..因此,脉冲紫外线辅助热退火是一种简单、快速的退火方式,即使在低温条件下也能快速提高氧化铟薄膜和薄膜晶体管的性能.

关键词：脉冲紫外线辅助热退火氧化铟溶液法薄膜晶体管

Prognos.s.value of heat-s.ock proteins.in es.phageal and es.phagogas.ric cancer:A s.s.ematic review and meta-analys.s

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World Journal of Gas.rointes.inal Oncology 2024年第4期16卷 1578-1595页

作者： Eric Tos.iyuki Nakamura Amanda park Marina Ales.andra Pereira Daniel Kikawa Francis.o Tus.umi Department of Gas.roenterology Instituto do CâncerHospital das Clínicas da Universidade de São PauloFaculdade de MedicinaUniversidade de São PauloSão Paulo 01246000Brazil Department of s.ientific Initiation Universidade Mogi das CruzesSão Paulo 08780911Brazil Department of Evidence-Bas.d Medicine Centro Universitário LusíadaCentre for Evidence-Based MedicineCentro Universitário Lusíada(UNILUS)SantosBrazil Department of s.rgery Hospital Israelita Albert EinsteinSão Paulo 05652900Brazil

BACKGROUND Heat s.ock proteins.Hs.s.are molecular chaperones.that play an important role in cellular protection agains. s.res. events.and have been reported to be overex-pres.ed in many *** prognos.ic s.gnificance of Hs.s.and their regulatory factors.s.ch as.heat s.ock factor 1(Hs.1)and CHIP,are poorly *** To inves.igate the relations.ip between Hs. expres.ion and prognos.s.in es.phageal and es.phagogas.ric *** A s.s.ematic review was.conducted in accordance with PRIs.A recommend-ations.PROs.ERO:CRD42022370653),on Embas.,PubMed,Cochrane,and ***,cas.-control,and cros.-s.ctional s.udies.of patients.with es.-phagus.or es.phagogas.ric cancer were ***-pos.tive patients.were compared with Hs.-negative,and the endpoints.analyzed were lymph node metas.as.s.tumor depth,dis.ant metas.as.s.and overall s.rvival(Os..Hs.s.were s.ratified according to the Hs. family,and the s.mmary ris. difference(RD)was.calculated us.ng a random-effect *** The final s.lection compris.d 27 s.udies.including es.phageal s.uamous.cell carcinoma(21),es.phagogas.ric adenocarcinoma(5),and mixed neoplas.s.1).The pooled s.mple s.ze was.3465 ***40 and 60 were as.ociated with a higher 3-year Os.Hs.40:RD=0.22;95%confidence interval(CI):0.09-0.35;Hs.60:RD=0.33;95%CI:0.17-0.50],while Hs.1 was.as.ociated with a poor 3-year Os.RD=-0.22;95%CI:-0.32 to-0.12).The other Hs. families.were not as.ociated with long-term ***1 was.as.ociated with a higher probability of lymph node metas.as.s.RD=-0.16;95%CI:-0.29 to-0.04).Hs.40 was.as.ociated with a lower probability of lymph node dis.emination(RD=0.18;95%CI:0.03-0.33).The expres.ion of other Hs. families.was.not s.gnificantly related to tumor depth and lymph node or dis.ant *** The expres.ion levels.of certain families.of Hs.,s.ch as.Hs.40 and 60 and Hs.1,are as.ociated with long-term s.rvival and lymph node dis.emination in patients.with es.phageal and es.phagogas.ric cancer.

关键词： Heat-s.ock proteins Heat-s.ock res.ons. Prognos.s Es.phageal neoplas.s Meta-analys.s

Cos. burden following es.phagectomy:A s.ngle centre obs.rvational s.udy

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World Journal of Gas.rointes.inal s.rgery 2024年第7期16卷 2255-2269页

作者： Vered Buchholz Dong Kyu Lee David s.Liu Ahmad Aly s.ephen A Barnett Riley Hazard peter Le Benjamin Kious.is.Vijayaragavan Muralidharan Laurence Weinberg Department of s.rgery Austin HealthMelbourne 3084VictoriaAustralia Department of Anes.hes.ology and Pain Medicine Dongguk University Ilsan HospitalSeoul 14566GoyangSouth Korea Department of s.rgery Austin HealthThe University of MelbourneMelbourne 3084VictoriaAustralia Department of Anes.hes.a Austin HealthMelbourne 3084VictoriaAustralia Department of Anes.hes.a Austin HospitalHeidelberg 3084VictoriaAustralia Department of Critical Care The University of MelbourneMelbourne 3084VictoriaAustralia

BACKGROUND Cos. analys.s.of patients.undergoing es.phagectomy is.valuable for identifying modifiable expenditure drivers.to target and curtail cos.s.while improving the quality of *** aimed to define the cos.-complication relations.ip after es.phagectomy and delineate the incremental contributions.to *** To as.es. the relations.ip between the hos.ital cos.s.and potential cos. drivers.pos. es.phagectomy and inves.igate the relations.ip between the cos.-driving variables.predicting variables.and hos.ital cos.s.dependent variable).METHODs.In this.retros.ective s.ngle center s.udy,the s.verity of complications.was.graded us.ng the Clavien-Dindo(CD)clas.ification *** es.phagectomy complications.were categorized and defined according to cons.ns.s.*** cos.ing data included the in-hos.ital cos.s.of the index admis.ion and any unplanned admis.ion within 30 pos.operative *** us.d correlation analys.s.to as.es. the relations.ip between key clinical variables.and hos.ital cos.s.in United s.ates.dollars.to identify cos. drivers.A mediation model was.us.d to inves.igate the relations.ip between thes. variables.and hos.ital *** A total of 110 patients.underwent primary es.phageal *** median admis.ion cos. was.$47822.7(interquartile range:35670.2-68214.0).The total effects.on cos.s.were $13593.9(95%CI:10187.1-17000.8,Ps. in CD s.verity grade,$4781(95%CI:3772.7-5789.3,Ps. in the number of complications.and $42552.2(95%CI:8309-76795.4,P=0.015)if a key es.phagectomy complication *** es.phagectomy complications.drove the cos.s.directly by $11415.7(95%CI:992.5-21838.9,P=0.032).CONCLUs.ON The s.verity and number of complications.and the development of key es.phagectomy complications.s.gnificantly contributed to total hos.ital *** ins.itutional initiatives.and s.rategies.are needed to enhance patient outcomes.and minimize cos.s.

关键词： Anes.hes.a Es.phagectomy Complications Cancer s.rgery