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Oral fluoroquinolones and the risk of Achilles tendon rupture

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Journal of Sport and Health Science 2024年第6期13卷 749-750页

作者： peter Vibe Rasmussen Jarl Emanuel Strange Anders holt Department of Cardiology Herlev-Gentofte University HospitalCopenhagen 2730Denmark Department of Cardiology Bispebjerg-Frederiksberg University HospitalCopenhagen 2400Denmark Department of Cardiology Rigshospitalet University HospitalCopenhagen 2100Denmark

Dear editor,Fluoroquinolones(FQs)are a class of antibiotics used to treat bacterial infections,such as lower respiratory,gastrointestinal,and urinary tract *** to its broad-spectrum action and wide availability,it is ... 详细信息

关键词： prescribed spectrum action

New insights into calcium,dairy and colon cancer

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World Journal of Gastroenterology 2008年第28期14卷 4429-4433页

作者： peter R holt Senior Research Associate Rockefeller UniversityProfessor of Medicine (Emeritus)Columbia UniversityNew YorkNY10065United States

This paper is to review recent information about the relationship of calcium and dairy foods to colon cancer. The review focuses on primary prevention, discusses the potential components in dairy foods that might be anti-neoplastic, reviews the epidemiologic information and describes intervention studies demonstrating efficacy of calcium and vitamin D in reducing colorectal polyp recurrence. Since vitamin D is important in cancer prevention, pertinent data is discussed and potential mechanisms of actions presented. Calcium and vitamin D are important agents for the primary prevention of colorectal neoplasia.

关键词： Colorectal cancer Dairy foods Calcium Vitamin D Colorectal polyp recurrence Colon cancer prevention

Controlling and Evaluating the Structure and Morphology of Polymers on Multiple Scales

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Journal of Materials Science and Chemical Engineering 2015年第12期3卷 48-60页

作者： Geoffrey R. Mitchell Ana Tojeira Thomas Gkourmpis James J. holt peter Harris Marilena Pezzuto Centre for Rapid and Sustainable Product Development Institute Polytechnic of Leiria Marinha Grande Portugal Innovation & Technology Borealis AB Stenungsund Sweden Department of Physics University of Reading Whiteknghts Reading UK Centre for Advanced Microscopy University of Reading Whiteknights Reading UK CNR-Istituto di Chimica e Tecnologia dei Polimeri Pozzuoli Italy

Crystalline polymers spontaneously form hierarchical structures although the precise manner in which these scales of structure are interconnected especially terms of the formation and evolution of the complete structure remains unclear. We have set out to control these scales of structure by introducing additional components which self-assemble in to nano-scale units which then direct the crystallisation of the polymer matrix. In other words, we first assemble a low concentration top-level structure which is designed to template or direct the sub-sequent crystallisation of the matrix polymer. This top level structure takes on the role of controlling the structure. We have set out to both establish the design principles of such structures and to develop experimental procedures which allow us to follow the formation of such complex hierarchical polymer structures. In particular we focus of the relationships between these different levels of structure and time sequence of events required for the structure to evolve in the targeted manner. In this programme, we have exploited time-resolving small-angle X-ray scattering and electron microscopy together with neutron scattering to probe and quantify the different scales of structure and their evolution. We highlight new neutron scattering instrumentation which we believe have great potential in the growing field of hierarchical structures in polymers. The addition of small quantities of nanoparticles to conventional and sustainable thermoplastics leads to property enhancements with considerable potential in a number of areas Most engineered nano-particles are highly stable and these exist as nano-particles prior to compounding with the polymer resin, they remain as nano- particles during the active use as well as in the subsequent waste and recycling streams. In this work we also explore the potential for constructing nano-particles within the polymer matrix during processing from organic compounds selected to provide nano

关键词： Component Semi-Crystalline Polymers Morphology Texture Nucleation Growth Shear Flow

如何改进外科手术结局应监测手术资料并在当地和全国采取措施

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英国医学杂志中文版 2008年第4期11卷 203-204页

作者： peter J E holt Jan D Poloniecki Matt M Thompson 秦宏(译) 血管外科临床讲师伦敦市圣乔治血管研究所SW17 0QT 伦敦市伦敦大学圣乔治社区健康科学学院 SW17 ORE 伦敦市圣乔治血管研究所不详

有越来越多的外科手术结局正在被国家审计部门审核，并通过未经校正的“各医院积分表”的形式公布。有两项相关研究报道了两种不同的外科手术结局与表现的测量方法——一种方法用于腹股沟疝修补术，而另一种用于经皮冠状动脉介入手术。... 详细信息

有越来越多的外科手术结局正在被国家审计部门审核，并通过未经校正的“各医院积分表”的形式公布。有两项相关研究报道了两种不同的外科手术结局与表现的测量方法——一种方法用于腹股沟疝修补术，而另一种用于经皮冠状动脉介入手术。应鼓励公众对外科手术结局进行审核，但是这些资料和统计学分析应该是可信、

关键词：手术结局外科手术资料经皮冠状动脉介入手术腹股沟疝修补术监测统计学分析审计部门

接种沙门氏菌苗可使新生雏鸡和强制换羽母鸡得到免疫保护

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国外畜牧学（猪与禽） 2007年第2期27卷 46-48页

作者：胡宇 Filip Van Immerseel Paul Barrow peter holt Ulrich Methner Richard Ducatelle 比利时根特大学英国动物健康研究所美国农业部/ARS东南家禽研究实验室

过去人们常认为,由于刚出壳雏鸡的免疫系统尚未发育成熟,同时肠道内缺乏有益的微生物,因而处于高度的敏感期,此时接种沙门氏菌苗产生的保护作用很有限。然而,最新的研究表明,在这些敏感期接种疫苗,可诱发产生保护作用。

关键词：接种疫苗免疫保护强制换羽新生雏鸡菌苗母鸡保护作用发育成熟

Introduction to time series and forecasting 2nd ed.

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丛书名： Springer texts in statistics

2002年

作者： peter J. Brockwell Richard A. Davis

ISBN: (数字)9780387216577

ISBN: (纸本)038721657X;9780387216577;9788181284044;8181284046;0387953515;9780387953519

Some of the key mathematical results are stated without proof in order to make the underlying theory accessible to a wider audience. The book assumes a knowledge only of basic calculus, matrix algebra, and elementary statistics. The emphasis is on methods and the analysis of data sets. The logic and tools of model-building for stationary and nonstationary time series are developed in detail and numerous exercises, many of which make use of the included computer package, provide the reader with ample opportunity to develop skills in this area.;The core of the book covers stationary processes, ARMA and ARIMA processes, multivariate time series and state-space models, with an optional chapter on spectral analysis. Additional topics include harmonic regression, the Burg and Hannan-Rissanen algorithms, unit roots, regression with ARMA errors, structural models, the EM algorithm, generalized state-space models with applications to time series of count data, exponential smoothing, the holt-Winters and ARAR forecasting algorithms, transfer function models and intervention analysis. Brief introductions are also given to cointegration and to nonlinear, continuous-time and long-memory models.;The time series package included in the back of the book is a slightly modified version of the package ITSM, published separately as ITSM for Windows, by Springer-Verlag, 1994. It does not handle such large data sets as ITSM for Windows, but like the latter, runs on IBM-PC compatible computers under either DOS or Windows (version 3.1 or later). The programs are all menu-driven so that the reader can immediately apply the techniques in the book to time series data, with a minimal investment of time in the computational and algorithmic aspects of the analysis.

关键词： Timeseries analysis.

来源：畅想之星图书光盘版（南... 评论

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手术结果数据：谨慎诠释手术结果数据

英国医学杂志中文版 2008年第6期11卷 381-381页

作者： peter J E holt Matt M Thompson Jan D Poloniecki 韩肖燕(译) 向阳(校) clinical lecturer in vascular surgery professor of vascular surgery St George's Vascular Institute London SW17 0QTSt George's University of London London SW17 ORE 不详

外科手术结果数据包括手术量、再次人院率和医疗程序风险的全面评估，可在英国国民健康保险网（***／Pages／***）上获得^[1]。我们认为，报道的数据不够精确，常常过低估计。此外，许多的数据资料仅为发表，而不是为了清楚明白地向公... 详细信息

外科手术结果数据包括手术量、再次人院率和医疗程序风险的全面评估，可在英国国民健康保险网（***／Pages／***）上获得^[1]。我们认为，报道的数据不够精确，常常过低估计。此外，许多的数据资料仅为发表，而不是为了清楚明白地向公众展示^[2]。

关键词：手术结果诠释医疗程序健康保险数据资料手术量