检索结果-南通市图书馆

Results of selective decontamination with oral neomycin and metronidazole for major colorectal surgery in Australia:A cohort study

引用

Laparoscopic, Endoscopic and Robotic Surgery 2024年第2期7卷 72-78页

作者： James Wei Tatt Toh Devansh Shah Henry Wang Charlotte Kwik Joseph Do Woong Choi Chelsie Leonie Beinke Paul Morris Eleni Baird-Gunning Geoffrey peter collins Fiona Gavegan Karen Shedden Toufic El-Khoury Nimalan Pathma-Nathan Kerry Hitos Department of Colorectal Surgery Westmead HospitalWestmeadNew South WalesAustralia The University of Sydney Westmead HospitalWestmeadNew South WalesAustralia Western Sydney University New South WalesAustralia University of Notre Dame New South WalesAustralia Westmead Research Centre for Evaluation of Surgical Outcomes Westmead HospitalSydneyAustralia

Objective The role of selective decontamination with oral antibiotics(OABs)and mechanical bowel preparation(MBP)prior to elective colorectal surgery is still widely *** objective of this study was to compare the outcomes of selective decontamination with neomycin,metronidazole and MBP compared to those of decontamination with MBP alone or with no *** Selective decontamination with neomycin and metronidazole combined with bowel preparation was introduced prior to elective colorectal surgery as part of an enhanced recovery after surgery program at Westmead Hospital,a major Australian tertiary referral hospital,between June 2017 and January *** between short-term outcomes of OAB+MBP and MBP/no preparation were made using prospectively collected data on length of stay(LOS),readmission,mortality within 30 days,anastomotic leakage(AL),surgical site infection(SSI),urinary tract infection,deep venous thrombosis and/or pulmonary embolism,pneumonia,and ***-up was limited to hospital stays and subsequent presentations within the health district within thirty days of *** Mann-Whitney U test was used to analyse continuous data,and the chi-square test was used for categorical *** and multivariate regression modelling was performed to identify risk factors associated with an increased likelihood of SSI and *** Patients with oral neomycin and metronidazole combined with bowel preparation had reduced superficial SSI(2.7%vs.7.6%,p=0.043)and overall complications(32.7%vs.44.6%,p=0.020),particularly Clavien-Dindo 1 complications(7.3%vs.16.5%,p=0.009).However,the differences in AL(2.7%vs.4.5%,p=0.369)and organ/space SSI(1.3%vs.3.7%,p=0.327)were not statistically *** median LOS(6 d vs.6 d,p=0.370)was not different between the *** Selective decontamination with neomycin and metronidazole reduces the risk of SSIs and overall *** was a trend to toward a lower AL,but this differ

关键词： Neomycin Metronidazole Colorectal surgery Anastomotic leakage Surgical site infection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Using Inductance as a Tuning Parameter for RF Meta-atoms

引用

Nano-Micro Letters 2012年第2期4卷 103-109页

作者： Derrick Langley Ronald A.Coutu peter J.collins Air Force Institute of Technology Wright-Patterson Air Force Base

The resonant frequency of metamaterials structured with split ring resonator(SRR) meta-atoms is determined primarily through the capacitance and inductance of the individual meta-atoms. Two designs that vary inductance incrementally were modeled, simulated, fabricated, and tested to investigate the role inductance plays in metamaterial designs. The designs consisted of strategically adding sections to the SRR to increase the inductance, but in a manner that minimized capacitance variations. Each design showed a shift in resonant frequency that was proportional to the length of the added section. As the length of each section was increased, the resonant frequency shifted from 2.78 GHz to 2.18 GHz.

关键词： Inductance Meta-atom Metamaterial Split Ring Resonator Radio Frequency Resonance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Proceedings of the 1st World Congress on Integrated Computational Materials Engineering (ICME) 1

引用

2011年

作者： John Allison peter collins George Spanos

ISBN: (数字)9781118147726

ISBN: (纸本)9780470943199

In its most advanced form, Integrated Computational Materials Engineering (ICME) holistically integrates manufacturing simulation, advanced materials models and component performance analysis. This volume contains thirty-five papers presented at the 1st World Congress on Integrated Computational Materials Engineering. Modeling processing-microstructure relationships, modeling microstructure-property relationships, and the role of ICME in graduate and undergraduate education are discussed. Ideal as a primary text for engineering students, this book motivates a wider understanding of the advantages and limitations offered by the various computational (and coordinated experimental) tools of this field.

关键词： Materials science Data processing Congresses.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Infection does not increase long-term mortality in patients with acute severe alcoholic hepatitis treated with corticosteroids

引用

World Journal of Gastroenterology 2017年第11期23卷 2052-2059页

作者： Ashwin D Dhanda Ashish Sinha Vicky Hunt Sarah Saleem Matthew E Cramp peter L collins Institute of Translational and Stratified Medicine Plymouth University Peninsula Schools of Medicine and Dentistry South West Liver Unit Plymouth Hospitals NHS Trust Department of Liver Medicine University Hospitals Bristol NHS Foundation Trust

AIM To determine whether infection in patients with acute severe alcoholic hepatitis(AAH) treated with corticosteroids is associated with increased *** Consecutive patients with AAH were treated with steroids and recruited to the study. Clinically relevant infections(body temperature > 38 ℃ or 0.25 ×109/L, consolidation on chest radiograph or clinically relevant positive microbiological culture of bodily fluid) were recorded prospectively. Clinical and laboratory parameters were recorded and survival at 90 d and 6 mo was determined. Univariate analysis of factors associated with 90-d mortality was performed and significant variables included in a multivariate *** Seventy-two patients were included in the final analysis(mean age 47.9 years, 26% female, mean discriminant function 53.0). Overall mortality in the group occurred in 15(21%), 23(32%) and 31(43%) at day 28, day 90 and 1 year respectively. 36(50%) had a clinically relevant infection during their hospitalisation(23 after initiation of steroids). The median time to development of incident infection after commencement of steroids was 10 d. The commonest site of infection was ascites(31%) and bacteraemia(31%) followed by urinary tract(19%) and respiratory tract(8%). Forty-one separate organisms were isolated in 33 patients; the most frequent genus was Escherichia(22%) and Enterococcus(20%). Infection was not associated with 90-d or 1 year mortality but was associated with higher creatinine, model for end-stage liver disease and Lille score. Baseline urea was the only independent predictor of 90-d *** Clinically relevant infections are common in patients with AAH but are not associated with increased 90-d or 1 year mortality.

关键词： Alcoholic hepatitis Escherichia Infection Lille score Corticosteroids

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Immune dysfunction in acute alcoholic hepatitis

引用

World Journal of Gastroenterology 2015年第42期21卷 11904-11913页

作者： Ashwin D Dhanda peter L collins School of Clinical Sciences University of Bristol NIHR Academic Clinical Lecturer in Hepatology Institute of Translational and Stratified Medicine Plymouth University Peninsula Schools of Medicine and Dentistry South West Liver Unit Plymouth Hospitals NHS Trust Department of Liver Medicine University Hospitals Bristol NHS Foundation Trust

Acute alcoholic hepatitis(AAH) is a serious complication of alcohol misuse and has high short term mortality. It is a clinical syndrome characterised by jaundice and coagulopathy in a patient with a history of recent heavy alcohol use and is associated with profound immune dysfunction with a primed but ineffective immune response against pathogens. Here, we review the current knowledge of the pathogenesis and immune defects of AAH and identify areas requiring further study. Alcohol activates the immune system primarily through the disruption of gut tight junction integrity allowing the escape of pathogenassociated molecular particles(PAMPs) into the portal venous system. PAMPs stimulate cells expressing toll-like receptors(mainly myeloid derived cells) and initiate a network of intercellular signalling by secretion of many soluble mediators including cytokines and chemokines. The latter coordinates the infiltration of neutrophils, monocytes and T cells and results in hepatic stellate cell activation, cellular damage and hepatocyte death by necrosis or apoptosis. On the converse of this immune activation is the growing evidence of impaired microbial defence. Neutrophils have reduced phagocytic capacity and oxidative burst and there is recent evidence that T cell exhaustion plays a role in this.

关键词： Alcoholic hepatitis Alcoholic liver disease Toll-l

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular targets in the treatment of alcoholic hepatitis

引用

World Journal of Gastroenterology 2012年第39期18卷 5504-5513页

作者： Ashwin D Dhanda Richard WL Lee peter L collins C Anne McCune Department of Liver Medicine University Hospitals Bristol NHS Foundation TrustBS2 8HW BristolUnited Kingdom Department of Cellular and Molecular Medicine School of Clinical SciencesUniversity of BristolBS9 1TD BristolUnited Kingdom

Alcohol related costs to health and society are high. One of the most serious complications of alcohol misuse to the individual is the development of alcoholic hepatitis (AH), a clinical syndrome of jaundice and progressive inflammatory liver injury in patients with a history of recent heavy alcohol use. It has a poor outcome and few existing successful therapies. The use of glucocorticoids in patients with severe AH is still controversial and there remains a group of patients with glucocorticoid-resistant disease. However, as our understanding of the pathogenesis of the condition improves there are opportunities to develop new targeted therapies with specific actions to control liver inflammation without having a detrimental effect on the immune system as a whole. In this article we review the molecular mechanisms of AH concentrating on the activation of the innate and adaptive immune response. We consider existing treatments including glucocorticoids, anti-tumor necrosis factor therapy and pentoxifylline and their limitations. Using our knowledge of the disease pathogenesis we discuss possible novel therapeutic approaches. New targets include pro-inflammatory cytokines such as interleukin (IL)-17, chemokines and their receptors (for example IL-8, CXCL9 and CXCR3) and augmentation of anti-inflam- matory molecules such as IL-10 and IL-22. And there is also future potential to consider combination therapy to selectively modulate the immune response and gain control of disease.

关键词： Alcoholic hepatitis Tumour necrosis factor-m Pentoxifylline Interleukins Chemokine receptors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

collins German-English, English-German dictionary: unabridged / 4th ed. 4th ed.

引用

1999年

作者： by peter Terrell ... [et al.] = Pons collins Grossw鑟rterbuch f鑥r Experten und Universit鑑t : De...

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Is liver biopsy necessary in the management of alcoholic hepatitis?

引用

World Journal of Gastroenterology 2013年第44期19卷 7825-7829页

作者： Ashwin D Dhanda peter L collins C Anne McCune Department of Liver Medicine University Hospitals Bristol NHS Foundation Trust Bristol BS2 8HW United Kingdom School of Clinical Sciences University of Bristol Bristol BS2 8HW United Kingdom

Acute alcoholic hepatitis(AAH)is characterised by deep jaundice in patients with a history of heavy alcohol use,which can progress to liver failure.A clinical diagnosis of AAH can be challenging to make in patients without a clear alcohol history or in the presence of risk factors for other causes of acute liver *** causes of acute on chronic liver failure such as sepsis or variceal haemorrhage should be *** biopsy remains the only reliable method to make an accurate ***,there is controversy surrounding the use of liver biopsy in patients with AAH because of the risks of performing a percutaneous biopsy and limitations in access to transjugular *** review the existing literature and find there are few studies directly comparing clinical and histological diagnosis of *** the small number of studies that have been conducted the correlation between a clinical and histological diagnosis of AAH is *** to this lack of agreement together with difficulties in accessing transjugular liver biopsy outside tertiary referral centres and research institutions,we cannot advocate universal biopsy for AAH but there remains a definite role for liver biopsy where there is clinical diagnostic doubt or dual *** adds value in a clinical trial context to ensure a homogeneous trial population and to further our understanding of the disease *** prospective studies are required to determine whether non-invasive markers can be used to accurately diagnose AAH.

关键词： Alcoholic hepatitis Liver biopsy Diagnosis Prognosis Transjugular liver biopsy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Cluster Analysis of Lifestyle and Health Habits of Youth from Two Geographically and Culturally Diverse Countries

引用

Open Journal of Preventive Medicine 2014年第4期4卷 193-203页

作者： Yahya Al-Nakeeb Lorna J. Dodd Mark Lyons peter collins Anwar Al-Nuaim College of Education Qatar University Doha Qatar Department of Physical Education King Faisal University Dammam Saudi Arabia Department of Psychology and Counselling Newman University Birmingham UK Faculty of Education and Health Sciences Univer-sity of Limerick Limerick Ireland School of Human Sciences Newman University Birmingham UK

Objectives: Obesity is a leading risk factor for global mortality, promoted by poor dietary habits and sedentary behaviour. This study explores the clustering and differences in dietary habits, body mass index (BMI) and physical activity (PA) amongst youth from United Kingdom (UK) and Saudi Arabia (SA). Methods: 2290 males and females aged 15-17 years completed a self-report questionnaire and an objective measure of BMI. Results: Youth from SA had a higher prevalence of overweight/obesity and lower levels of PA than youth from the UK. Males were more physically active than females across both countries. Three clusters were identified: a “high risk” cluster with least healthy dietary habits, low PA and high BMI;a “moderate cluster” with moderate healthy dietary habits, PA and BMI;a “low risk” cluster with healthiest dietary habits, greatest PA and the lowest BMI compared to the other clusters. There were more SA youth in the high and moderate risk clusters compared to UK youth. Conclusions: Exploring cross-cultural and demographic characteristics of youth enables the identification of similarities and differences that might lead to the development of universal intervention strategies.

关键词： Clustering Risk Factors Youth Diet Physical Activity Body Mass Index

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

地球演化历史中氧逸度变化对壳幔循环启动、风化和超大陆循环的指示

引用

Science Bulletin 2024年第1期69卷 97-102页

作者：王瑞邬绍宸 Roberto F.Weinberg William J.collins peter A.Cawood State Key Laboratory of Geological Processes and Mineral Resources Institute of Earth SciencesChina University of GeosciencesBeijing 100083China Frontiers Science Center for Deep-time Digital Earth China University of Geosciences(Beijing)Beijing 100083China School of Earth Atmosphere and EnvironmentMonash UniversityClayton VIC 3800Australia The Institute for Geoscience Research Curtin UniversityPerth WA 6102Australia

We apply a zircon redox index to a global compilation of detrital zircons to track the variation of oxidation state,expressed asΔFMQ,through Earth's *** from I-type rocks,which comprise mantle and crustal igneous protoliths,including tonalite–trondhjemite–granodiorites(TTGs),generally have a high oxidation state(ΔFMQ>0).In contrast,zircons from igneous rocks derived from supracrustal source rocks(S-type)are commonly reduced(ΔFMQ0 over the last 3 *** that the redox state of magmas is independent of crustal thickness and silica variation,and elevated values are likely more closely related to tectonic setting,we suggest that the consistent averageΔFMQ>0 from ca.3.5 Ga onwards relates to recycling of oceanic lithosphere back into the mantle in what eventually became established as subduction *** more reduced magmas associated with sedimentary sources,became established at 2.6 Ga,presumably in response to continental rocks rising above sealevel,and follow peaks of productivity associated with the supercontinent cycle.

关键词： Oxidation state Supercontinent Weathering Subduction Zircon Granite

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：