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Periprocedural complications and one-year outcomes after catheter ablation for treatment of atrial fibrillation in elderly patients:a nationwide Danish cohort study

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Journal of Geriatric Cardiology 2021年第11期18卷 897-907页

作者： Jesper Nielsen Kristian Hay Kragholm Sofie Brix Christensen Arne Johannessen Christian Torp-Pedersen Steen Buus Kristiansen peter Karl Jacobsen peter Steen hansen Mogens Stig Djurhus Christoffer Polcwiartek peter Søgaard Anna Margrethe Thøgersen Uffe Jakob Ortved Gang Ole Dan Jørgensen Filip Lyng Lindgren Sam Riahi Department of Cardiology Aalborg University HospitalDenmark Department of Cardiology Gentofte HospitalCopenhagen University HospitalDenmark Department of Clinical Research and Cardiology Nordsjaellands HospitalHillerødDenmark Department of Cardiology Skejby University HospitalDenmark Department of Cardiology RigshospitaletCopenhagen University HospitalDenmark Mølholm Clinic VejleDenmark Department of Cardiology Odense University hospitalDenmark Department of Cardiology Roskilde University HospitalDenmark Department of Thoracic Surgery Odense University HospitalDenmark AF-Study group Aalborg University Hospital Denmark Clinical Institute Aalborg UniversityDenmark

OBJECTIVES To investigate complications within 30-days following first-time ablation for atrial fibrillation(AF),including a composite of cardiac tamponade,hematoma requiring intervention,stroke or death,in patients≥75 years of age,compared to pa-tients aged 65−74 *** addition,one-year all-cause mortality and AF relapse were ***&RESULTS All patients receiving their first catheter ablation for AF between 2012 and 2016 were identified us-ing Danish nationwide *** aged 65−74 years served as the reference group for patients≥75 *** of AF within one year was defined as cardioversion following a three-month blanking period,re-ablation or confirmed relapse within *** composite complication outcome did not differ between the two age groups,with 39/1554(2.8%)in patients 65−74 years of age,versus 5/199(2.5%)in older patients(adjusted HR=0.94),95%CI:0.37−2.39,P=0.896).Patients≥75 years or older had no increased hazard of death within 30 days after the procedure,with an incidence of 3/1554(0.2%)in younger pa-tients and 2/199(1.0%)in patients≥75 years of age(adjusted HR=4.71,95%CI:0.78−28.40,P=0.091).There was no difference in relapse of AF after one year between age groups(≥75 years adjusted HR=1.00,95%CI:0.78-1.26,P=0.969).CONCLUSION In patients≥75 years of age selected for catheter ablation for AF,the incidence of periprocedural complica-tions,as well as one-year freedom from AF showed no statistical difference,when compared to patients 65−74 years of age.

关键词： patients fibrillation atrial

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高中生生殖道感染/性知识、态度和行为调查

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中国公共卫生 2006年第9期22卷 1028-1029页

作者：梁秀余莉曾光吴淑艳 peter hansen 深圳市福田区计划生育服务中心 518048 中国疾病预防控制中心 WHO生殖与健康研究部

目的了解深圳市高中生生殖道感染(RTIs)/性相关知识、态度、行为(KAP)及求医、求助情况,探讨解决方法。方法采取社会学访谈、流行病学问卷调查方法,选择深圳市普通、职业高中的学生作为访谈及问卷调查对象。结果艾滋病(AIDS)知识总知晓... 详细信息

目的了解深圳市高中生生殖道感染(RTIs)/性相关知识、态度、行为(KAP)及求医、求助情况,探讨解决方法。方法采取社会学访谈、流行病学问卷调查方法,选择深圳市普通、职业高中的学生作为访谈及问卷调查对象。结果艾滋病(AIDS)知识总知晓率为50%,RTIs症状的知晓率为0,安全套知识正确回答率64.55%,使用率低;对早恋、婚前性行为多持理解及支持态度;多数去私人诊所求医,大多向朋友、同学求助。结论当今中学生性观念和性行为均日趋开放,而性知识、性病、AIDS预防知识缺乏,求医、求助方式不安全;因此,在中学阶段开展AIDS教育应与性健康教育结合,正确引导其求医、求助方式,以此作为中学生预防AIDS一项重要措施。

关键词：高中生 RTIs 性行为流行病学调查

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Detection and Persistence of Clinical <i>Escherichia coli</i>in Drinking Water Evaluated by a Rapid Enzyme Assay and qPCR

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Advances in Microbiology 2012年第3期2卷 252-262页

作者： Annette S. Bukh Nina E. hansen peter Roslev Department of Biotechnology Chemistry and Environmental Engineering Aalborg University Aalborg Denmark

The aims of this study were to evaluate two methods, qPCR and a chemiluminescent assay (ColiLight II), for rapid detection of E. coli in water, and to examine the survival and persistence of clinical E. coli in drinking water and biofilm using qPCR and ColiLight II. qPCR and ColiLight II were compared with a cultivation-based method (MPN), and survival and persistence of four clinical E. coli strains in water and biofilms on stainless steel (SS) and polyethylene (PE) surfaces were studied in a flow-through reactor with non-disinfected drinking water using ColiLight II, qPCR, ATP bioluminescence, and MPN. ColiLight II and qPCR correlated well with MPN. In drinking water, some clinical E. coli strains showed prolonged survival in drinking water flow-through systems, and persisted 3 - 3.4 times longer than the theoretical washout due to incorporation into biofilms. Strain specific attributes can significantly affect detection and persistence of E. coli in drinking water matrices.

关键词： Biofilm Clinical E. coli Chemiluminescent Assay Lab-Scale Drinking Water Reactor System Drinking Water qPCR

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Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis

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World Journal of Gastroenterology 2007年第23期13卷 3232-3236页

作者： Fin Stolze Larsen Ben Vainer Martin Eefsen peter Nissen Bjerring Bent Adel hansen Department of Hepatology RigshospitaletUniversity Hospital of CopenhagenCopenhagen 2100Denmark Department of Pathology RigshospitaletUniversity Hospital of CopenhagenCopenhagen 2100Denmark

AIM: To determine the eff icacy of tacrolimus on clinical status, histopathological status and biochemical markers in patients with steroid refractory autoimmune hepatitis (AIH). METHODS: Retrospectively, clinical parameters, biochemistry and histology were obtained from patient records. RESULTS: Nine patients [8 females/1 male, median age 32 (range 16-64) years] were identified to have received tacrolimus for a median duration of 18 (12-37) mo. Before initiation of tacrolimus treatment the patients were maintained on a prednisolone dose of 20 mg daily (range 20-80 mg/d), which was tapered to 7.5 (5-12.5) mg/d (P = 0.004). Alanine aminotransferase and immunoglobulin-G concentrations decreased from 154 (100-475) to 47(22-61) U/L (P = 0.007), and from 16 (10-30.2) to 14.5 (8.4-20) g/L (P = 0.032), respectively. All patients showed improvement of the liver inflammatory activity, as determined by the Ishak score (P = 0.016), while the degree of f ibrosis tended to decrease (P = 0.049). CONCLUSION: The use of low dose tacrolimus can lead to biochemical and histologic improvement of inflammation with no progression of the stage of f ibrosis in patients with steroid refractory AIH. Low dose tacrolimus therapy also allows substantial reduction of prednisone dose.

关键词： Autoimmune hepatitis Tacrolimus Prednisone Azathioprine Mycophenolate mofetil Liver failure

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结合实际应用浅析M2M与物联陬

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现代制造 2015年第41期 48-50页

作者： peter Koldig hansen 丹麦Secomea公司

“Secomea重新创造了用于M2M、物联网或类似概念的远程通信方案。”这句描述摘录于Secomea在美国分销商发出的一封客户简报。这个引用准确地描述了现实需求与流行词之间的巨大差距。本文将相关术语放在远程通信场景的方式来尝试定义M2M... 详细信息

“Secomea重新创造了用于M2M、物联网或类似概念的远程通信方案。”这句描述摘录于Secomea在美国分销商发出的一封客户简报。这个引用准确地描述了现实需求与流行词之间的巨大差距。本文将相关术语放在远程通信场景的方式来尝试定义M2M（机器到机器）和物联网（Internet of Things），并为选择具有前瞻性的工业设备远程访问方案提供方向和指引（图1）。

关键词： M2M 应用远程通信通信方案访问方案工业设备物联网分销商

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评《欧洲统一买卖法》第八编时效规则

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私法研究 2016年第1期19卷 185-204页

作者： peter MΦgelvang-hansen 朱晓峰(译) 丹麦哥本哈根商学院中央财经大学法学院

目次一、一般条款二、时效期间及其开始三、时效期间的中止四、时效期间的重新起算五、时效的效力六、协议修改译者注:中国民法典编纂在即,学者们起草的建议稿各有千秋,其中中国法学会发布的《中华人民共和国民法典·民法总则专家建议稿...

目次一、一般条款二、时效期间及其开始三、时效期间的中止四、时效期间的重新起算五、时效的效力六、协议修改译者注:中国民法典编纂在即,学者们起草的建议稿各有千秋,其中中国法学会发布的《中华人民共和国民法典·民法总则专家建议稿(征求意见稿)》。

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Worsening Clinical Outcome with Increasing Number of So-Called Off-Label or Unapproved Indications for Use of Drug Eluting Stents

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World Journal of Cardiovascular Diseases 2016年第7期6卷 224-234页

作者： Anders M. Galløe Ulrik Abildgaard Henning Kelbæk Niels Bligaard Jørgen L. Jeppesen Leif Thuesen peter R. hansen Department of Cardiology Zealand University Hospital Roskilde Denmark Department of Cardiology Copenhagen University Hospital Gentofte Denmark Department of Cardiology Copenhagen University Hospital Bispebjerg Denmark Department of Medicine Copenhagen University Hospital Glostrup Denmark Department of Cardiology Aalborg University Hospital Aalborg Denmark

Objective: We explored the impact of increasing number of off-label patient and lesion character-istics on 5-year clinical outcome following implantation of first generation drug eluting stents. Furthermore we tried to assess if stent performance might be improved if the off-label character-istics present were taken into account to guide the stent brand selection. Design: A total of 2888 coronary lesions treated with first generation drug eluting stents were classified for eventual presence of 18 different off-label characteristics and correlated to the 5-year clinical outcome by multiple stepwise Cox regression analysis. Results: The composite of cardiac death, myocardial infarction and target vessel revascularization (major adverse cardiac event, MACE) was 16.7% in cases with zero off-label characteristics and showed a stepwise increased rate up to 32.7% in cases with 5 off-label characteristics. The MACE rate for the sirolimus eluting stent appears to be 10% lower than the paclitaxel stent group and it may be further reduced by 10% - 18% if the off-label characteristics present in each case were taken into account to guide the stent brand selection. Conclusion: With increasing number of concomitantly appearing off-label characteristics there is a stepwise increase in MACE rate. The MACE rate may be reduced if the off-label characteristics were used to guide the stent brand selection.

关键词： Drug Eluting Stents

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Are monitoring and evaluation systems adequate to report the programmatic coverage of HIV services among key populations in countries?

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Infectious Diseases of Poverty 2019年第4期8卷 75-81页

作者： Jinkou Zhao Sonia Arias Garcia Ed Ngoksin Jesus Maria Garcia Calleja Chinelo Ogbuanu Sandra Kuzmanovska Nicholas Oliphant David Lowrance Nathalie Zorzi peter M.hansen Keith Sabin The Global Fund to fight AIDS Tuberculosis and MalariaChemin du Pommier 40Grand-Saconnex 1218GenevaSwitzerland Center for Global Health School of Public HealthNanjing Medical UniversityNanjingChina Jiangsu Provincial Center for Disease Control and Prevention NanjingChina Strateg ic Information and Evaluation Department the Joint United Nations Programme on HIV/AIDSGenevaSwitzerland Department of HIV/AIDS World Health OrganizationGenevaSwitzerland

There was no global guidance or agreement regarding when a country has an adequate system to report on the service packages among human immunodeficiency virus(HIV)key *** article describes an approach to categorizing the system in a country for reporting the service package among HIV key *** approach consists of four dimensions,namely the epidemiological significance,comprehensiveness of the service packages,geographic coverage of services,and adequacy of the monitoring *** proposed categorization approach utilizes available information and can inform the improvement of the service delivery and monitoring systems among HIV key populations.

关键词： services among service

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“诺维信去渍酶”——一种将食品污渍去除及白度维护提升至新高度的酶

“诺维信去渍酶”——一种将食品污渍去除及白度维护提升至新高度...

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2004（第八届）国际表面活性剂和洗涤剂会议

作者：邓军 peter Skagerlind Anders Bo hansen Lund 诺维信中国投资有限公司诺维信中国投资有限公司诺维信中国投资有限公司

酶作为洗涤剂中的关键组分,可以分解织物上各种污渍例如淀粉,蛋白质和脂肪。诺维信去渍酶可以提高多种与消费者息息相关的食品污渍的去除,并且增强衣物的白度维护和总体清洁。本文将介绍这种酶的来源,应用,好处以及由此支持的消费者卖点... 详细信息

酶作为洗涤剂中的关键组分,可以分解织物上各种污渍例如淀粉,蛋白质和脂肪。诺维信去渍酶可以提高多种与消费者息息相关的食品污渍的去除,并且增强衣物的白度维护和总体清洁。本文将介绍这种酶的来源,应用,好处以及由此支持的消费者卖点,包括去除顽固污渍和增强衣物的白度维护。

关键词：诺维信去渍酶淀粉酶污渍去除白度维护

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Diagnosis of intraductal papillary mucinous neoplasm using endoscopic ultrasound guided microbiopsies:A case report

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World Journal of Gastrointestinal Endoscopy 2018年第7期10卷 125-129页

作者： Charlotte Vestrup Rift Bojan Kovacevic John Gásdal Karstensen Julie Plougmann Pia Klausen Anders Toxvaerd Evangelos Kalaitzakis Carsten Palnaes hansen Jane Preuss Hasselby peter Vilmann Department of Pathology Copenhagen University Hospital RigshospitaletCopenhagen 2100Denmark Gastro Unit Division of EndoscopyCopenhagen University Hospital Herlev and GentofteHerlev 2730Denmark Gastro Unit Division of SurgeryCopenhagen University HospitalHvidovre2650 HvidovreDenmark Department of Pathology Copenhagen University Hospital Herlev and GentofteHerlev 2730Denmark Department of Gastrointestinal surgery Copenhagen University Hospital RigshospitaletCopenhagen 2100Denmark

Pancreatic cysts are increasingly diagnosed due to expanding use of cross-sectional imaging,but current diagnostic modalities have limited diagnostic ***,a novel through-the-needle microbiopsy forceps has become available,offering the possibility of obtaining cyst-wall *** present a case of 41-year-old male with chronic pancreatitis and a 2-cm pancreatic cyst,initially considered a ***,endoscopic ultrasou-nd guided microbiopsies were successfully obtained,which surprisingly revealed an intraductal papillary mucinous neoplasm of mixed subtype with low grade *** conclusion,obtaining biopsies from the wall of the pancreatic cystic lesions with this novel instrument is feasible and,as demonstrated in this case,can possibly alter the clinical *** offered enough cellular material,allowing supplemental gene mutation analysis,which combined with other modalities could lead to a more individual approach when treating pancreatic ***,prospective studies are warranted before routine clinical implementation.

关键词： Microbiopsy Pancreatic cyst Endoscopic ultrasound-fine needle aspiration Intraductal papillary mucinous neoplasm Chronic pancreatitis

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