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Hardware Architecture of Polyphase Filter Banks Performing Embedded Resampling for Software-Defined Radio Front-Ends

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ZTE Communications 2012年第1期10卷 54-62,70页

作者： Mehmood Awan Yannick Le Moullec peter koch Fred Harris Technology Platforms Section Dept. of Electronic Systems Aalborg University Dept. of Electrical & Computer Engineering San Diego State University

In this paper, we describe resourceefficient hardware architectures for softwaredefined radio （SDR） frontends. These architectures are made efficient by using a polyphase channelizer that performs arbitrary sample rate changes, frequency selection, and bandwidth control. We discuss area, time, and power optimization for field programmable gate array （FPGA） based architectures in an Mpath polyphase filter bank with modified Npath polyphase filter. Such systems allow resampling by arbitrary ratios while simultaneously performing baseband aliasing from center frequencies at Nyquist zones that are not multiples of the output sample rate. A nonmaximally decimated polyphase filter bank, where the number of data loads is not equal to the number of M subfilters, processes M subfilters in a time period that is either less than or greater than the Mdataload ＇ s time period. We present a loadprocess architecture （LPA） and a runtime architecture （RA）（based on serial polyphase structure） which have different scheduling. In LPA, Nsubfilters are loaded, and then M subfilters are processed at a clock rate that is a multiple of the input data rate. This is necessary to meet the output time constraint of the down-sampled data. In RA, Msubfilters processes are efficiently scheduled within Ndataload time while simultaneously loading N subfilters. This requires reduced clock rates compared with LPA, and potentially less power is consumed. A polyphase filter bank that uses different resampling factors for maximally decimated, underdecimated, overdecimated, and combined upand downsampled scenarios is used as a case study, and an analysis of area, time, and power for their FPGA architectures is given. For resourceoptimized SDR frontends, RA is superior for reducing operating clock rates and dynamic power consumption. RA is also superior for reducing area resources, except when indices are prestored in LUTs.

关键词： SDR FPGA Digital Frontends Polyphase Filter Bank Embedded Resampling

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Polyphase Filter Banks for Embedded Sample Rate Changes in Digital Radio Front-Ends

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ZTE Communications 2011年第4期9卷 3-9页

作者： Mehmood Awan Yannick Le Moullec peter koch Fred Harris Technology Platforms Section Dept. of Electronic Systems Aalborg University Denmark Dept. of Electrical & Computer Engineering San Diego State UniversityCA USA

This paper presents efficient processing engines for software-defined radio （SDR） front-ends. These engines, based on a polyphase channelizer, perform arbitrary sample-rate changes, frequency selection, and bandwidth control. This paper presents an M-path polyphase filter bank based on a modified N-path polyphase filter. Such a system allows resampling by arbitrary ratios while performing baseband aliasing from center frequencies at Nyquist zones that are not multiples of the output sample rate. This resampling technique is based on sliding cyclic data load interacting with cyclic-shifted coefficients. A non-maximally-decimated polyphase filterbank （where the number of data loads is not equal to the number of M subfilters） processes M subfilters in a time period that is less than or greater than the M data loads. A polyphase filter bank with five different resampling modes is used as a case study for embedded resamp/ing in SDR front-ends. These modes are （i） maximally decimated, （ii） Under-decimated, （iii） over-decimated, and combined up- and down-sampling with （iv） single stride length, and （v） multiple stride lengths. These modes can be used to obtain any required rational sampling rate change in an SDR front-end based on a polyphase channelizer. They can also be used for translation to and from arbitrary center frequencies that are unrelated to the output sample rates.

关键词： SDR digital front-ends polyphase filter bank embedded resampling

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用于产生多层结构的帘式涂布

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经济导报（纸业技术） 2008年第1期 73-77页

作者： peter koch TSE Troller公司的

多层帘式涂布机只需经过一次涂布操作就能够赋予喷墨打印纸表面三层结构（底层、吸收层和顶层）。

关键词：多层结构三层结构打印纸涂布机

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令人烦恼的视窗

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程序员 2013年第2期 84-86页

作者： peter-Paul koch Luke Wroblewski Stephanie Rieger Lyza Danger Gardner

设备制造商为了让自己的设备拥有更清晰的屏幕，往往选择提高屏幕的像素，但有些时候像素的增加并不能让用户获得良好的阅读体验。本文以苹果公司的移动设备为例，为我们揭示了为什么高像素的屏幕会给用户的阅读带来“烦恼”。

关键词：烦恼设备制造商视窗移动设备苹果公司屏幕像素阅读

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DIFFERENTIATION OF THE TRUE AND INTERVENTION INDUCED PSEUDO-MILKING EFFECT BY INTRAVASCULAR ULTRASOUND

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Chinese Medical Journal 1995年第3期 70-71页

作者： peter Kearney Lothar koch Gunter Gorge Ramund Erbel Department of Cardiolgy University Essen GermanyDepartment of Cardiolgy University Essen GermanyDepartment of Cardiolgy University Essen GermanyDepartment of Cardiolgy University Essen Germany

We have shown the value of intravascular ultrasound (IVUS) in the evaluation of myocardial bridging (MB). The purpose of the study was to elucidate the mechanism of inter-

关键词： IVUS DIFFERENTIATION OF THE TRUE AND INTERVENTION INDUCED PSEUDO-MILKING EFFECT BY INTRAVASCULAR ULTRASOUND

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Biologic agents for anterior cruciate ligament healing: a systematic review

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World Journal of Orthopedics 2016年第9期7卷 592-603页

作者： Berardo Di Matteo Markus Loibl Luca Andriolo Giuseppe Filardo Johannes Zellner Matthias koch peter Angele ⅠOrthopaedic and Traumatologic Clinic - Biomechanics and Technology Innovation Laboratory Rizzoli Orthopaedic Institute Department of Trauma Surgery University Regensburg Medical Centre Sporthopaedicum Regensburg

AIM To systematically review the currently available literature concerning the application of biologic agents such as platelet-rich plasma(PRP) and stem cells to promote anterior cruciate ligament(ACL) *** A systematic review of the literature was performed on the use of biologic agents(i.e., PRP or stem cells) to favor ACL healing during reconstruction or repair. The following inclusion criteria for relevant articles were used: Clinical reports of any level of evidence, written in English language, on the use of PRP or stem cells during ACL reconstruction/repair. Exclusion criteria were articles written in other languages, reviews, or studies analyzing other applications of PRP/stem cells in knee surgery not related to promoting ACL *** The database search identified 394 records that were screened. A total of 23 studies were included in the final analysis: In one paper stem cells were applied for ACL healing, in one paper there was a concomitant application of PRP and stem cells, whereas in the remaining21 papers PRP was used. Based on the ACL injury pattern, two papers investigated biologic agents in ACL partial tears whereas 21 papers in ACL *** at the quality of the available literature, 17 out of 21 studies dealing with ACL reconstruction were randomized controlled trials. Both studies on ACL repair were case *** There is a paucity of clinical trials investigating the role of stem cells in promoting ACL healing both in case of partial and complete tears. The role of PRP is still controversial and the only advantage emerging from the literature is related to a better graft maturation over time, without documenting beneficial effects in terms of clinical outcome, bone-graft integration and prevention of bony tunnel enlargement.

关键词： Platelet-rich plasma Growth factors Stem cells Anterior cruciate ligament reconstruction Anterior cruciate ligament repair Anterior cruciate ligament healing Sports medicine Regenerative medicine

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Intraprocedural gastric juice analysis as compared to rapid urease test for real-time detection of Helicobacter pylori

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World Journal of Gastroenterology 2023年第10期29卷 1638-1647页

作者： Riccardo Vasapolli Florent Ailloud Sebastian Suerbaum Jens Neumann Nadine koch Lukas Macke Jörg Schirra Julia Mayerle peter Malfertheiner Christian Schulz Medical DepartmentⅡ University Hospital LMU MunichMunich 81377Germany Deutsches Zentrum für Infektionsforschung Partner Site MunichMunich 81377Germany Max von Pettenkofer Institute Faculty of MedicineLudwig-Maximilians University of MunichMunich 80336Germany National Reference Center for Helicobacter pylori Munich 81377Germany Institute of Pathology Faculty of MedicineLudwig-Maximilians-University of MunichMunich 81377Germany

BACKGROUND Endofaster is an innovative technology that can be combined with upper gastrointestinal endoscopy(UGE)to perform gastric juice analysis and real-time detection of Helicobacter pylori(***).AIM To assess the diagnostic performance of this technology and its impact on the management of *** in the real-life clinical *** Patients undergoing routine UGE were prospectively *** were taken to assess gastric histology according to the updated Sydney system and for rapid urease test(RUT).Gastric juice sampling and analysis was performed using the Endofaster,and the diagnosis of *** was based on real-time ammonium *** detection of *** served as the diagnostic gold standard for comparing Endofaster-based *** diagnosis with RUT-based *** *** A total of 198 patients were prospectively enrolled in an *** diagnostic study by Endofasterbased gastric juice analysis(EGJA)during the *** for RUT and histological assessment were performed on 161 patients(82 men and 79 women,mean age 54.8±19.2 years).*** infection was detected by histology in 47(29.2%)***,the sensitivity,specificity,accuracy,positive predictive value,and negative predictive value(NPV)for *** diagnosis by EGJA were 91.5%,93.0%,92.6%,84.3%,and 96.4%,*** patients on treatment with proton pump inhibitors,diagnostic sensitivity was reduced by 27.3%,while specificity and NPV were *** and RUT were comparable in diagnostic performance and highly concordant in *** detection(κ-value=0.85).CONCLUSION Endofaster allows for rapid and highly accurate detection of *** during *** may guide taking additional biopsies for antibiotic susceptibility testing during the same procedure and then selecting an individually tailored eradication regimen.

关键词： Helicobacter pylori diagnostic Chronic gastritis Gastric juice Endofaster Rapid urease test Antimicrobial susceptibility testing

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Organic Nanocolumn Arrays and Organic Solar Cells

Organic Nanocolumn Arrays and Organic Solar Cells

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全国第八届有机固体电子过程暨华人有机光电功能材料学术讨论会

作者： Ingo Salzmann peter Schfer Jürgen P.Rabe Norbert koch Institut für Physik Humboldt-Unirersitat zu BerlinNewtonstrasse 15BerlinGerman 12489

Solar cells based on organic semiconductors contain bulk heterojunctions,where the two phases of donor and acceptor materials should alternate on the length scale of the exciton diffusion ***,the two phases are interdigitated and crystalline,to ensure high charge carrier mobility and reduced recombination. Crystalline nanocolumn arrays of two widely studied organic semiconductors,i.e.,Fullerene(C60) and penta-

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Liver-directed treatment is associated with improved survival and increased response to immune checkpoint blockade in metastatic uveal melanoma:results from a retrospective multicenter trial

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Frontiers of Medicine 2023年第5期17卷 878-888页

作者： Elias A.T.koch Anne Petzold Anja Wessely Edgar Dippel Markus Eckstein Anja Gesierich Ralf Gutzmer Jessica C.Hassel Harald Knorr Nicole Kreuzberg Ulrike Leiter Carmen Loquai Friedegund Meier Markus Meissner peter Mohr Claudia Pföhler Farnaz Rahimi Dirk Schadendorf Max Schlaak Kai-Martin Thoms Selma Ugurel Jochen Utikal Michael Weichenthal Beatrice Schuler-Thurner Carola Berking Markus V.Heppt Department of Dermatology Uniklinikum ErlangenFriedrich-Alexander-University Erlangen-Nürnberg(FAU)91054ErlangenGermany Comprehensive Cancer Center Erlangen—European Metropolitan Area of Nürnberg(CCC ER-EMN) 91054ErlangenGermany Deutsches Zentrum Immuntherapie(DZI) Uniklinikum ErlangenFriedrich-Alexander-University Erlangen-Nürnberg(FAU)91054ErlangenGermany Bavarian Cancer Research Center(BZKF) Uniklinikum ErlangenÖstliche Stadtmauerstraße 3091054ErlangenGermany Department of Dermatology Ludwigshafen Medical Center67059LudwigshafenGermany Institute of Pathology Uniklinikum ErlangenFriedrich-Alexander-University Erlangen-Nürnberg91054ErlangenGermany Department of Dermatology University Hospital Würzburg97080WürzburgGermany Skin Cancer Center Minden Department of DermatologyMühlenkreiskliniken AöRRuhr UniversityBochum Campus Minden32423MindenGermany Skin Cancer Center Department of Dermatology and National Center for Tumor Diseases(NCT)University Hospital Heidelberg69120HeidelbergGermany Department of Ophthalmology Uniklinikum ErlangenFriedrich-Alexander-University Erlangen-Nürnberg(FAU)91054ErlangenGermany Department of Dermatology and Venereology Skin Cancer Center at the Center of Integrated Oncology(CIO)Köln BonnUniversity Hospital of Cologne50937CologneGermany Department of Dermatology Center for DermatooncologyUniversity Hospital Tübingen72056TübingenGermany Department of Dermatology University Medical Center Mainz55131MainzGermany Skin Cancer Center at the University Cancer Center Dresden and National Center for Tumor Diseases&Department of Dermatology University Hospital Carl Gustav Carus01307DresdenGermany Department of Dermatology Venereology and AllergologyGoethe University60590Frankfurt am MainGermany Department of Dermatology Elbeklinikum21614BuxtehudeGermany Department of Dermatology Saarland University Medical School66421Homburg/SaarGermany Department of Dermatology and Allergy Munich University Hospital(LMU)81377MunichGermany Departmen

Metastases of uveal melanoma(UM)spread predominantly to the *** to low response rates to systemic therapies,liver-directed therapies(LDT)are commonly used for tumor *** impact of LDT on the response to systemic treatment is unknown.A total of 182 patients with metastatic UM treated with immune checkpoint blockade(ICB)were included in this *** were recruited from prospective skin cancer centers and the German national skin cancer registry(ADOReg)of the German Dermatologic Cooperative Oncology Group(DeCOG).Two cohorts were compared:patients with LDT(cohort A,n=78)versus those without LDT(cohort B,n=104).Data were analyzed for response to treatment,progression-free survival(PFS),and overall survival(OS).The median OS was significantly longer in cohort A than in cohort B(20.1 vs.13.8 months;P=0.0016)and a trend towards improved PFS was observed for cohort A(3.0 vs.2.5 months;P=0.054).The objective response rate to any ICB(16.7%vs.3.8%,P=0.0073)and combined ICB(14.1%vs.4.5%,P=0.017)was more favorable in cohort *** data suggest that the combination of LDT with ICB may be associated with a survival benefit and higher treatment response to ICB in patients with metastatic UM.

关键词： uveal melanoma liver-directed therapy immune checkpoint blockade SIRT anti-PD-1 anti-CTLA-4

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CYP2D6PCR基因型与DXT表型和基因芯片检测的比较(英文)

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中国临床药理学与治疗学 2002年第2期7卷 100-105页

作者：严奉祥廖端芳 CHOU Wen-Hwei WEDLUND peter-J ROBBINS-WEILER Dorris-K RYDER Thomas-B PERBOST ClotildeQuintiles Inc FAIRCHILD Maureen koch Walter-H 南华大学药物药理研究所衡阳421001 College of Pharmacy University of Kentucky Quintiles Inc Affymetrix Santa Clara CA Roche Molecular Inc Alameda CA

目的 :为了评价CYP2D6的基因型和表型的联系以及基因芯片在CYP2D6多基因分析中的应用。方法 :2 4 2健康志愿者 ,口服dextromethorphan后收集尿液测定其代谢率 ,收集 2 0ml血提取DNA ,并通过基因特异性PCR和 / (或 )基因芯片分析CYP2D6 ... 详细信息

目的 :为了评价CYP2D6的基因型和表型的联系以及基因芯片在CYP2D6多基因分析中的应用。方法 :2 4 2健康志愿者 ,口服dextromethorphan后收集尿液测定其代谢率 ,收集 2 0ml血提取DNA ,并通过基因特异性PCR和 / (或 )基因芯片分析CYP2D6 2——— 11, 17和多拷贝CYP2D6基因 ,其中 5个基因 ( 3、 4、 6、 7和 9)用PCR和CYD4 5 0基因芯片同时分析。结果 :CYP2D6基因型比表型更富有信息和更能反映CYP2D6酶的表达。CYP2D6 3、 4、 6、 7和 9的基因检测在CYP4 5 0基因芯片和基因特异性PCR中显示高度的一致性。结论 :基因芯片在检测基因多位点的多基因中是一个有发展前途和可靠的方法。

关键词： CYP2D6 表型基因型 PCR 寡核苷酸微陈列杂交

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