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The Ogaden Dyke Swarm: Red Sea Rifting Continued in the Somalia Plate?

Acta geologica Sinica(English Edition) 2016年第S1期90卷 56-58页

作者： Daniel MègE peter g.purcell Antoine BéZOS Fred JOURDAN Space Research Centre Polish Academy of Sciences Planetology and geodynamics Laboratory UMR CNRS 6112 University of Nantes P & R geological Consultants Western Australia Argon Isotope Facility Curtin University

Opening of the Red Sea started while the core of the lavas of the Ethiopian Large Igneous Province（LIP）was being erupted at;0 Ma（Hughes et al.,1991）and has continued to the *** the southern Red Sea,oceanic

关键词： Red Sea Rifting Continued in the Somalia Plate The Ogaden Dyke Swarm

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1H nuclear magnetic resonance spectroscopy-basedmetabonomic study in patients with cirrhosis and hepaticencephalopathy

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World Journal of Hepatology 2015年第12期7卷 1701-1707页

作者： Konstantinos John Dabos John Andrew Parkinson Ian Howard Sadler John Nicholas Plevris peter Clive Hayes Centre of Liver and Digestive Disorders Royal Infirmary of Edinburgh Department of Chemistry University of Strathclyde Department of Chemistry University of Edinburgh

AIM: To identify plasma metabolites used as biomarkers in order to distinguish cirrhotics from controls and ***: A clinical study involving stable cirrhotic patients with and without overt hepatic encephalopathy was designed. A control group of healthy volunteers was used. Plasma from those patients was analysed using 1H- nuclear magnetic resonance spectroscopy. We used the Carr purcell Meiboom gill sequence to process the sample spectra at ambient probe temperature. We used a gated secondary irradiation field for water signal suppression. Samples were calibrated and referenced using the sodium trimethyl silyl propionate peak at 0.00 ppm. For each sample 128 transients(FID's) were acquired into 32 K complex data points over a spectral width of 6 KHz. 30 degree pulses were applied with an acquisition time of 4.0 s in order to achieve better resolution, followed by a recovery delay of 12 s, to allow for complete relaxation and recovery of the magnetisation. A metabolic profile was created for stable cirrhotic patients without signs of overt hepatic encephalopathy and encephalopathic patients as well as healthy controls. Stepwise discriminant analysis was then used and discriminant factors were created to differentiate between the three ***: Eighteen stabled cirrhotic patients, eighteen patients with overt hepatic encephalopathy and seventeen healthy volunteers were recruited. Patients with cirrhosis had significantly impaired ketone body metabolism, urea synthesis and gluconeogenesis. This was demonstrated by higher concentrations of acetoacetate(0.23 ± 0.02 vs 0.05 ± 0.00, P glutamine(0.44 ± 0.08 vs 0.63 ± 0.03, P ginine(0.08 ± 0.01 vs 0.14 ± 0.02, P gher concentrations of glutamate(1.36 ± 0.25 vs 0.58 ± 0.04, P < 0.01), lactate(1.53 ± 0.11 vs 0.42 ± 0.05, P < 0.01),

关键词： Ketone bodies Branch chain amino acids glutamine glycolysis

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