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Proteome changes of porcine follicular fluid during follicle development

Journal of Animal Science and Biotechnology 2020年第2期11卷 367-379页

作者： Victor M.Paes Shengfa f.Liao Jose R.figueiredo Scott T.Willard peter L.Ryan Jean M.feugang Department of Animal and Dairy Sciences Mississippi State University4025 Wise CenterPO Box 9815StarkvilleMississippi State MS 39762USA Laboratory of Manipulation of Oocyte and Preantral follicles State University of CearáFortalezaCEBrazil

Background:Ovarian follicular fluid influences follicle and oocyte growth,but the fluctuation of its protein content during folliculogenesis has not been comprehensively *** we used a shotgun approach and bioinformatics analyses to investigate and compare the proteomes of porcine follicular fluid(pff)obtained from small(6–12 mm)***:follicular fluid samples containing highest estrogen levels were selected as non-atretic from small(SNA:26.1±15 ng/mL),medium(MNA:162±54 ng/mL),and large(LNA:290±37 ng/mL)follicles for proteomic *** detected 1627,1699,and 1756 proteins in SNA,MNA,and LNA samples,*** 60–63%of total proteins were specific to each sample,11–13%were shared in pairwise comparisons,and 247 proteins were shared among all *** categorization indicated comparable gene ontology(GO)terms distribution per cellular component,molecular function,and biological process categories across samples;however,the ranking of highly significantly enriched GO terms per category revealed differences between *** patterns of proteinto-protein interactions varied throughout follicle development,and proteins such as serine protease inhibitor,clade E(SERPINE);plasminogen activator,urokinase(PLAU);and plasminogen activator,urokinase receptor(PLAUR)appeared stage-specific to SNA,MNA,and LNA,***“complement and coagulation cascades”was the common major ***,properdin and fibulin-1 were abundant proteins that appeared absent in LNA ***:This study provides extensive and functional analyses of the pff proteome changes during folliculogenesis and offers the potential for novel biomarker discovery in pff for oocyte quality assessment.

关键词： follicular fluid folliculogenesis Pig Shotgun proteomic

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Obstruction Theory and Coincidences in Positive Codimension

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Acta Mathematica Sinica,English Series 2006年第5期22卷 1591-1602页

作者： Daciberg GONCALVES Jerzy JEZIERSKI peter WONG Departamento de Matemática-Instituto de Matemdtica e Estatística-Universidade de Sǎo Paulo Caixa Postal 66.281-CEP 05311-970 Sǎo Paulo-SP Brasil Department of Mathematics University of Agriculture Nowoursynowska 166 02766 Warszawa Poland Department of Mathematics Bates College Lewiston ME 04240 USA

Let f, g ： X→Y be two maps between closed manifolds with dim X ≥ dim Y = n ≥ 3. We study the primary obstruction on（f, g） to deforming f and g to be coincidence free on the n-th skeleton of X. We give examples f... 详细信息

关键词： Nielsen number Reidemeister number coincidence theory obstruction theory

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Glial-neuronal Sensory Organs:Evolutionary Journey from Caenorhabditis elegans to Mammals

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Neuroscience Bulletin 2020年第5期36卷 561-564页

作者： Yong Tang peter Illes Alexei Verkhratsky International Collaborative Centre on Big Science Plan for Purine Signalling Chengdu University of Traditional Chinese MedicineChengdu 610075China Acupuncture and Tuina School Chengdu University of TCMChengdu 610075China Key Laboratory of Sichuan Province for Acupuncture and Chronobiology Chengdu 610075China Rudolf-Boehm-Institut für Pharmakologie und Toxikologie Universitat LeipzigLeipzig 04107Germany faculty of Biology Medicine and HealthThe University of ManchesterManchester MI39PTUK

Recently,a paper published in Science reported discovery of sensory peripheral glial cells[1].This paper demonstrated a rather unexpected property of non-myelinating Schwann cells(also known as Remak cells)dwelling in the subepidermal border of the skin[2].These glial cells and their interactions with nociceptive nerve terminals were characterized using a variety of genetic labelling tools,transmission electron microscopy,immunocytochemistry.

关键词： myelin border property

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挪威云杉林枯枝落叶层元素浸提量的研究

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林业科学研究 2002年第5期15卷 505-514页

作者：王彦辉 peter Rademacher Horst flster 中国林业科学研究院森林生态环境与保护研究所北京100091 TheInstituteofSoilScienceandforestNutrition

对取自德国Solling的挪威云杉林的不同枯枝落叶层样品进行了一系列浸提实验 ,结果表明 ,枯落物分解程度、水∶物的比值和浸提液pH值都是元素浸提的主要控制因素。多数阳离子的浸提受到H+交换机制的很大影响 ,较低的pH值会导致较高的浸提... 详细信息

对取自德国Solling的挪威云杉林的不同枯枝落叶层样品进行了一系列浸提实验 ,结果表明 ,枯落物分解程度、水∶物的比值和浸提液pH值都是元素浸提的主要控制因素。多数阳离子的浸提受到H+交换机制的很大影响 ,较低的pH值会导致较高的浸提量 ;而较高的pH值和稀释作用导致的pH值升高会导致较低的浸提量。在水∶物的比值增加到某一数值之前 ,水∶物的比值增加会导致浸提液内元素浓度与枯落物元素含量的新平衡 ,并导致浸提量增大。另外一方面 ,水∶物的比值增加导致的pH值升高会成为新的限制因素 ,导致较低的浸提量 ,尤其对于 2、3价阳离子。这两种作用机制的复合效应使浸提量与水∶物的比值的关系曲线非常复杂。建立了森林枯枝落叶层元素含量 (T ,μmol(+ )·kg- 1)、浸提液pH值、水∶物的比值 (W ,kg·kg- 1)对元素浸提量 (Y ,μmol(+ )·kg- 1枯落物 )影响的数学模型。对Na+、K+,Ca2 +、Mg2 +、Mn2 +、Al3+和fet,模型为Y =A + (T -A)·exp(-B·pH) / [1+C·exp(-W) ];对H+,模型为Y =a +bW　c。对严重酸化的枯枝落叶层元素的浸提 ,不存在所期盼的最优水∶物的比值。水∶物的比值较低时 ,元素浓度比值变化较大 ;在水∶物的比值较高时 ,元素数量比值变化较大。但对严重酸化的枯枝落叶层元素进行浸提时 ,可把?

关键词：挪威云杉林枯枝落叶层元素浸提量土壤有机质

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Accounting for Some Aspects of Dark Matter and Dark Energy via Noncommutative Geometry

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Journal of Modern Physics 2017年第3期8卷 323-329页

作者： peter K. f. Kuhfittig Department of Mathematics Milwaukee School of Engineering Milwaukee WI USA

The purpose of this paper is to seek a connection between noncommutative geometry, an offshoot of string theory, and certain aspects of dark matter and dark energy. The former case is based on a simple mathematical argument showing that the main manifestation of dark matter in connection with flat galactic rotation curves is also a consequence of noncommutative geometry. The latter case requires an examination of the local effect of noncommutative geometry and the subsequent extension to the global phenomenon of an accelerating Universe.

关键词： Noncommutative Geometry Dark Matter Dark Energy

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The flow of non-starch polysaccharides along the gastrointestinal tract of broiler chickens fed either a wheat-or maize-based diet

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Animal Nutrition 2022年第2期9卷 138-142页

作者： Eunjoo Kim Natalie K.Morgan Amy fMoss Lily Li peter Ader Mingan Choct School of Environmental and Rural Science University of New EnglandArmidaleNSW 2351Australia BASf South East Asia 038987Singapore BASf SE 68623LampertheimGermany

The present study characterised the types and amounts of non-starch polysaccharides(NSP)remaining undigested along the gastrointestinal tract(GIT)of broiler chickens offered a typical wheat-or maizebased ***-day old Cobb 500 mixed-sex chicks were assigned to 24 pens,with 10 birds/pen and 12 pens/*** were offered the experimental diets in 3 phases(starter,day 0 to 10;grower,day 11 to 24 and finisher,day 25 to 35).Excreta and digesta samples from the crop,gizzard,duodenum,jejunum,ileum and caeca were collected at 12 and 35 days of age,and analysed for the NSP *** wheat-based diet contained higher levels of soluble NSP than the maize-based diet,whereas insoluble NSP levels were similar between the 2 *** analysis of NSP constituents revealed that arabinoxylans were the primary NSP in the wheat-based diet,mostly in insoluble *** were the predominant NSP in the maize-based diet,followed by ***,birds offered the wheatbased diet presented higher levels of soluble NSP remaining in all gut sections compared to birds offered the maize-based diet,at both 12 and 35 days of age(Pf insoluble NSP in the gizzard was noted in birds fed both diets,but was more pronounced in birds offered the maize-based diet compared to the wheat-based diet,at both 12 and 35 days of age(Pfferences in the amounts and types of NSP delivered to the different gut sections when feeding wheat-compared to maize-based diets,particularly in the gizzard and the lower GIT of birds.

关键词： Broiler chickens Soluble fibre Insoluble fibre Non-starch polysaccharides

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A Comparative Study of the Local Heat Transfer Distributions Around Various Surface Mounted Obstacles

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Journal of Thermal Science 2014年第2期23卷 169-176页

作者： Robert Wyssmann Dirk Ullmer Alexandros Terzis peter Ott Group of Thermal Turbomachinery(GTT) cole Polytechnique Fédérale de Lausanne (EPFL)SCI-STI-POCH-1015LausanneSwitzerland

In many engineering applications,heat transfer enhancement techniques are of vital importance in order to ensure reliable thermal designs of convective heat transfer *** study examines experimentally the heat transfer characteristics on the base plate around various surface mounted *** convection coefficients are evaluated in the vicinity of each individual protruding body with great spatial resolution using the transient liquid crystal *** different obstacles of constant height-to-hydraulic diameter ratio(~1.3) are *** include:a cylinder,a square,a triangle,a diamond and a vortex generator of delta wing shape *** experiments were carried out over a range of freestream Reynolds numbers,based on the hydraulic diameter of each obstacle,varying from 4,000 to 13,*** results indicate a negligible effect of the flow speed on the heat transfer topological structure and a considerable effect of the obstacle geometry on the level and distribution of heat transfer enhancement.

关键词： surface obstacles heat transfer enhancement transient liquid crystal technique

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A Note on the Cosmological Constant in <i>f</i>(<i>R</i>) Gravity

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Journal of Applied Mathematics and Physics 2017年第4期5卷 933-938页

作者： peter K. f. Kuhfittig Department of Mathematics Milwaukee School of Engineering Milwaukee Wisconsin USA

The starting point in this note is f(R) modified gravity in a cosmological setting. We assume a spatially flat universe to describe late-time cosmology and the perfect-fluid equation of state to model the hypothesized dark energy. Given that on a cosmological scale, f(R) modified gravity must remain close to Einstein gravity to be consistent with observation, it was concluded that either (1) Einstein’s cosmological constant was the only acceptable model for the accelerated expansion, or that (2) the equation of state for dark energy was far more complicated than the perfect-fluid model and might even exclude a constant w.

关键词： Cosmological Constant f(R) Gravity

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Noncommutative Geometry and MOND

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Journal of High Energy Physics, Gravitation and Cosmology 2022年第3期8卷 642-646页

作者： peter K. f. Kuhfittig Department of Mathematics Milwaukee School of Engineering Milwaukee USA

Modified Newtonian dynamics (MOND) is a hypothesized modification of Newton’s law of universal gravitation to account for the flat rotation curves in the outer regions of galaxies, thereby eliminating the need for dark matter. Although a highly successful model, it is not a self-contained physical theory since it is based entirely on observations. It is proposed in this paper that noncommutative geometry, an offshoot of string theory, can account for the flat rotation curves and thereby provide an explanation for MOND. This paper extends an earlier heuristic argument by the author.

关键词： Noncommutative Geometry MOND flat Galactic Rotation Curves Dark Matter

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Risk for colorectal cancer in ulcerative colitis:Changes,causes and management strategies

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World Journal of Gastroenterology 2008年第25期14卷 3937-3947页

作者： peter Laszlo Lakatos Laszlo Lakatos 1st Department of Medicine Semmelweis University 1st Department of Medicine Csolnoky F. County Hospital

The risk of colorectal cancer for any patient with ulcer-ative colitis is known to be elevated, and is estimated to be 2% after 10 years, 8% after 20 years and 18% after 30 years of disease. Risk factors for cancer in-clude extent and duration of ulcerative colitis, primary sclerosing cholangitis, a family history of sporadic colorectal cancer, severity of histologic bowel inflam-mation, and in some studies, young age at onset of colitis. In this review, the authors discuss recent epide-miological trends and causes for the observed chang-es. Population-based studies published within the past 5 years suggest that this risk has decreased over time, despite the low frequency of colectomies. The crude annual incidence rate of colorectal cancer in ulcerative colitis ranges from approximately 0.06% to 0.16% with a relative risk of 1.0-2.75. The exact mechanism for this change is unknown; it may partly be explained by the more widespread use of maintenance therapy and surveillance colonoscopy.

关键词： Ulcerative colitis Colorectal cancer Riskfactors Surveillance Chemprevention

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