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A rare diagnosis:testicular dysgenesis with carcinoma in situ detected in a patient with ultrasonic microlithiasis

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Asian Journal of Andrology 2005年第4期7卷 445-447,页

作者： Christina E.Hoei-Hansen peter Sommer Ewa Rajpert-de Meyts Niels E.Skakkebaek department of Growth and Reproduction department of Urology University Hospital of Rigshospitalet2100 Copenhagen Denmark

A rare case is presented where a dysgenetic testis with microinvasive carcinoma in situ （CIS, also known as intratubular germ cell neoplasm of unclassified type [IGCNU] and testicular intraepithelial neoplasia [TIN]） with microinvasion to rete testis and the interstitial tissue was found in a 32-year-old man presenting with mild scrotal pain and ultrasonic testicular microlithiasis. Knowledge of the association of ultrasound and CIS is important to diagnose patients at the stage prior to development of an overt germ cell tumor. The patient had three of four disorders considered symptoms of the testicular dysgenesis syndrome （TDS）： a dysgenetic left testicle with CIS, a mild left-sided cryptorchidism （high positioned scrotal hypotrophic testis） and a slightly reduced semen quality. Therefore, it should be kept in mind that a patient with one TDS symptom may harbour the other, even CIS or testicular cancer. Accordingly, patients with one TDS symptom ought to be examined for the presence of the others, and if more that one is present, extra concern is warranted.

关键词： testicular cancer carcinoma in situ testis microlithiasis testicular dysgenesis syndrome

The optimization of phenolic compounds extraction from cactus pear(Opuntia ficus-indica) skin in a reflux system using response surface methodology

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Asian Pacific Journal of Tropical Biomedicine 2013年第6期3卷 436-442页

作者： Aguirre Joya Jorge de La Garza Toledo Heliodoro Zugasti cruz Alejandro Belmares Cerda Ruth Aguilar Cristóbal No Food Research department School of ChemistryUniversidad Autonóma de Coahuila Basic Science department Universidad Autonóma Agraria Antonio Narro

Objective:To extract,quantify,and evaluate the phenolic content in Opuntia ficus-indica skin for their antioxidant capacity with three different methods(ABTS,DPPH,and lipid oxidation)and to optimize the extraction conditions[time,temperature and ethanol concentration)in a reflux ***:The extraction process was done using a reflux system.A San CristobalⅡexperimental design with three variables and three levels was *** variables evaluated were time of extraction(h),concentration of ethanol(%,v/v)and temperature(°C).The extraction process was optimized using a response surface ***:It was observed that at higher temperature more phenolic compounds were extracted,but the antioxidant capacity was *** optimum conditions for phenolic compounds extraction and antioxidant capacity mixing the three methods were as Follows:45%of ethanol,80℃and 2 hours of *** obtained in our results are little higher that other previously ***:It can he concluded the by-products of Opuntia ficus-indica represent a good source of natural antioxidants with possible applications in food,cosmetics or drugs industries.

关键词： Opuntia ficus-indica Reflux Phenolics Antioxidants Prickly pear Response surface methodology

CHARACTERIZATION AND QUANTITATION OF VASOPRESSIN METABOLITES IN RAT BRAIN BY SPECIFIC RADIOIMMUNOASSAY AND HIGH-PRESSURE LIQUID CHROMATOGRAPHY

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Science China Chemistry 1986年第8期29卷 832-843页

作者：王新昌,J.peter H.BURBACH,JEROEN TENHAAF,DAVID de WIED department of Biology Nanjing University Rudolf Magnus Institute for Pharmacology Medical Faculty University of Utrecht The netherlands. Rudolf Magnus Institute for Pharmacology Medical Faculty University of Utrecht The netherlands. Rudolf Magnus Institute for Pharmacology Medical Faculty University of Utrecht The netherlands.

The content of endogenons vasopressin (AVP1-9) and its metabolites in rat's various brain areas and pituitary gland was investigated by the combination techniques of high pressure liquid chromatography （HPLC） and radioimmunoassay （RIA）. In addition to the AVP1-9, several compounds with C-terminal AVP immunoreactivity were detected in hypothalamus, hippceampus, amygdala, medulla oblongata and septum. The C-terminal AVP1-9metabolites were virtually absent in the pituitary gland. In view of the highly potent and selective effects oa memory processes of AVP metabolites, some endogenous AVP metabolites in the brain may play an important role in the central nervous system （CNS） function.

关键词： Cyt AV CHARACTERIZATION AND QUANTITATION OF VASOPRESSIN METABOLITES IN RAT BRAIN BY SPECIFIC RADIOIMMUNOASSAY AND HIGH-PRESSURE LIQUID CHROMATOGRAPHY RAT

Assessment of pressure drop in conical spouted beds of biomass by artificial neural networks and comparison with empirical correlations

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Particuology 2022年第11期70卷 1-9页

作者： Juan F.Saldarriag Yuby cruz Idoi Estiati Mikel Tellabide Martin Olazar department of Civil and Environmental Engineering Universidad de los AndesCarrera 1Este#19A-40BogotaColombia department of Chemical Engineering University of the Basque CountryBarrio Sarriena s/nLeioaSpain

Pressure drop is an essential parameter in the operation of conical spouted beds(CSB)and depends on its geometric factors and materials *** materials,like biomass,are complex to treat and,unlike other gas–solid contact methods,CSB turn out to be a suitable technology for their *** neural networks were used in this study for the prediction of operating and peak pressure drops,and their performance has been compared with that of empirical correlations reported in the ***,a multi-layer perceptron network with backward propagation was used due to its ability to model non-linear multivariate *** fitting of the experimental data of both operating and peak pressure drop was significantly better than those reported in the literature,specifically in the case of the peak pressure drop,with R^(2) being ***,artificial neural networks have been proven suitable for the prediction of pressure drop in CSB.

关键词： Pressure drop Artificial neural networks Biomass Spouted bed

Performance of a Phase Change Material Battery in a Transparent Building

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Fluid Dynamics & Materials Processing 2023年第3期19卷 783-805页

作者： peter van den Engel Michael Malin Nikhilesh Kodur Venkatesh Luigi Antonio de Araujo Passos delft University of Technology Delft2600 GAThe Netherlands CHAM Bakery HouseLondonSW195AUUK

This research evaluates the performance of a Phase Change Material(PCM)battery integrated into the climate system of a new transparent meeting *** main research questions are:a.“Can the performance of the battery be calculated?”and b.“Can the battery reduce the heating and cooling energy demand in a significant way?”The first question is answered in this *** order to be able to answer the second question,especially the way the heat loading in winter should be improved,then more research is *** addition to the thermal battery,which consists of Phase Change Material plates,the climate system has a cross-flow heat exchanger and a heat *** battery should play a central role in closing the thermal balance of the lightweight building,which can be loaded with hot return or cold outdoor *** temperature of the battery plates is monitored by multi-sensors and simulated by the use of PHOENICS(Computational Fluid Dynamics)and *** paper reports reasonable agreement between the numerical predictions and the measurements,with a maximum variance of 10%.The current coefficient of performance for heating and cooling is already high,more than *** is scope for increasing this much further by making use of the very low-pressure difference of the battery(below 25 Pascal),low pressure fans and the ventilation system as a whole.

关键词： Phase change material(PCM) heating ventilation and air-conditioning(HVAC) thermal battery heat exchangers passive energy

determination of drug,excipients and coating distribution in pharmaceutical tablets using NIR-CI

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Journal of Pharmaceutical Analysis 2012年第2期2卷 90-97页

作者： Anna Palou Jordi cruz Marcelo Blanco Jaume Tomàs Joaquín de los Ríos Manel Alcalà Unitat de Química Analítica Departament de QuímicaFacultat de CiènciesUniversitat Autònoma de Barcelona08193 BellaterraBarcelonaSpain Escola Universitària Salessiana de Sarrià Passeig Sant Joan Bosco7408017 BarcelonaSpain Esteve Farma c/Sant Martí s/n08197 MartorellesBarcelonaSpain

The growing interest of the pharmaceutical industry in Near Infrared-Chemical Imaging (NIR-CI) is a result of its high usefulness for quality control analyses of drugs throughout their production process (particularly of its non-destructive nature and expeditious data acquisition).In this work,the concentration and distribution of the major and minor components of pharmaceutical tablets are determined and the spatial distribution from the internal and external sides has been *** addition,the same NIR-CI allowed the coating thickness and its surface distribution to be *** were processed to extract the target data and calibration models constructed using the Partial Least Squares (PLS) *** concentrations of Active Pharmaceutical Ingredient (API) and excipients obtained for uncoated cores were essentially identical to the nominal values of the pharmaceutical *** the predictive ability of the calibration models applied to the coated tablets decreased as the coating thickness increased.

关键词： Near infrared Chemical Imaging (NIR-CI) Hyperspectral imaging Component distribution Tablet coating distribution Partial Least Squares (PLS) regression

Recreational team sports: The motivational medicine

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Journal of Sport and Health Science 2018年第2期7卷 129-131页

作者： Carlo Castagna Maysa de Sousa peter Krustrup Donald T.Kirkendall School of Sport and Exercise Sciences Faculty of Medicine and SurgeryUniversity of Rome Tor Vergata Fitness Training and Biomechanics Laboratory Technical DepartmentItalian Football Association Laboratory of Medical Investigation LIM-18Endocrinology DivisionSchool of MedicineUniversity of S?o Paulo department of Sports Science and Clinical Biomechanics Sport and Health Sciences Cluster (SHSC)University of Southern Denmark Sport and Health Sciences Faculty of Life and Environmental SciencesUniversity of Exeter James R.Urbaniak MDSport Sciences InstituteDuke University Medical Center

Remember way back when?When we were kids?We played games like soccer,basketball,rugby,and volleyball because they were *** we stayed with it long enough(and became good enough)we might have played competitively,where ... 详细信息

关键词：激发性运动娱乐橄榄球

Does cryptic dichromatism exist in the Saffron Finch(Sicalis flaveola)?Colorimetric variables and the avian visual model

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Avian Research 2023年第3期14卷 405-415页

作者： Lorena cruz-Bernate Camilo Espinosa-Bravo Hector Fabio Rivera-Gutierrez Ornithology and Animal Behavior Laboratory-OYCA GEAHNA GroupBiology Department of the Natural and Exact Sciences FacultyUniversidad del ValleCaliColombia Ecology and Evolution Vertebrates Group Biology InstituteNatural and Exact Sciences FacultyUniversidad de AntioquiaMedellínColombia

Sexual dichromatism,a particular type of sexual dimorphism,occurs in several species and has been associated with sexual *** some cases,the differences are so small that they are imperceptible to humans,but possibly detected by *** objective measurement of color with spectrophotometers and detailed analyses according to the perception ability of the avian eye have revealed that some species that were once considered to be monochromatic,are in fact dichromatic and able to perceive these *** the tropics,the Saffron Finch(Sicalis flaveola) does not present marked sexual dimorphism in coloration,which makes studies in behavioral ecology,natural history and population dynamics *** assess whether there is dichromatism in the species,the reflectance(between 300 and 700 nm) of ten body regions was measured in 196 wild adults in *** was determined using the CHD1 gene on the sex *** spectra were analyzed using:colorimetric variables and the avian visual *** found that reflectance shows a bimodal curve in all body regions,except the *** presented higher reflectance at long wavelengths,while for females this occurred in ultraviolet *** the visual model,we found that there are significant intrasexual differences;however only in crown coloration is there a possible perceived difference between *** conclude that in the Saffron Finch there are color differences between the sexes in all regions considering the physical phenomenon(reflectance),but in general,when evaluating color perception(avian visual model),there are no differences between the sexes in most of the body *** intrasexual differences are significant,indicating the possibility of these being signals that influence social interactions in the species.

关键词： Carotenoids Color discrimination Colombia Intrasexual signals Social selection Tanagers Tropical region

Conocarpus erectus L., a plant with a high content of structural sugars, ions and phenolic compounds, shows antioxidant and antimicrobial properties promoted by different organic fractions

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Asian Pacific Journal of Tropical Biomedicine 2018年第9期8卷 463-470页

作者： Dayane Kelly Dias do Nascimento Santos Weslley Henrique de Oliveira Melo Anastassia Mariáh Nunes de Oliveira Lima Iranildo Joseda cruz Filho Glaucia Manoella de Souza Lima Tulio Diego da Silva Maiara Celine de Moura Marcia Silva do Nascimento Ana Maria Souto Maior Thiago Henrique Napoleao Cristiane Moutinho Lagos de Melo department of Biochemistry Biosciences Centre Federal University of Pernambuco department of Antibiotics Biosciences Centre Federal University of Pernambuco Center of Strategic Technologies of the Northeast

Objective: To evaluate the structural and chemical composition of plant and the antioxidant and antimicrobial activities promoted by hexanic, ethanolic and ethyl acetate fractions obtained from leaves of Conocarpus ***: Organic fractions were characterized through UPLC-MS and *** potential was performed through DPPH and molybdenum phosphate *** and antifungal assays were performed in accordance with Clinical and Laboratory Standards Institute ***: The obtained biomass of Conocarpus erectus leaves showed the high presence of glucose(0.45 g/L), cellulose(28.69%), Na(55.126 μg/L) and K(31.163 μg/L).We identified seven compounds in the hexanic and ethyl acetate fractions, and eight compounds in ethanolic ***, phenolic compounds are prevalent in all organic fractions with values of(10.04 ± 0.24),(221.26 ± 1.84),(340.53 ± 0.84) mg/g GAE to hexanic, ethyl acetate and ethanolic fraction, *** results showed a high potential in ethyl acetate fraction(71.82 ± 6.87)% and(10.89 ± 0.05)% in DPPH and molybdenum phosphate techniques, *** ethanolic fraction showed moderate bacteriostatic and bactericidal activity against Staphylococcus aureus and presented a high fungistatic potential for all Candida species ***: Organic fractions obtained from leaves of Conocarpus erectus present antimicrobial and antioxidant properties, and these findings contribute to scientific information for the effectiveness on use of this plant in the development of a phytotherapic compound.

关键词： Combretaceae Phenolic compounds Antimicrobial activity Antioxidant