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World Journal of Clinical Cases 2016年第3期4卷 76-80页

作者： Nina Fluschnik Gunnar Lund peter moritz becher Stefan Blankenberg Kai Muellerleile Department of General and Interventional Cardiology University Heart Center Department of Diagnostic and Interventional Radiology University Medical Center Hamburg Eppendorf

This case report illustrates challenging aspects of diagnosis and treatment of isolated sarcoid heart disease(SHD) and the role of cardiovascular magnetic resonance(CMR) imaging. Here, we present a previously healthy 45-year-old man, who was admitted with pericardial effusion and symptoms of acute heart failure. CMR followed by targeted left ventricular endomyocardial biopsy(EMB) revealed the diagnosis of isolated SHD. The combined use of CMR and EMB was crucial in diagnosing SHD. Furthermore, this case report demonstrates the value of CMR for monitoring response to therapy and lesion healing.

关键词： Heart failure Cardiac sarcoidosis Cardiovascular magnetic resonance imaging Endomyocardial biopsy Internal cardiac defibrillator

Challenging aspects of treatment strategies in heart failure with preserved ejection fraction: “Why did recent clinical trials fail?”

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World Journal of Cardiology 2015年第9期7卷 544-554页

作者： peter moritz becher Nina Fluschnik Stefan Blankenberg Dirk Westermann Department of General and Interventional Cardiology University Heart Center Eppendorf

Heart failure(HF) is the leading cause of hospitalization among older adults and the prevalence is growing with the aging populations in the Western countries. Epidemiologic reports suggest that approximately 50% of patients who have signs or symptoms of HF have preserved left ventricular ejection fraction. This HF type predominantly affects women and the elderly with other co-morbidities, such as diabetes, hypertension, and overt volume status. Most of the current treatment strategies are based on morbidity benefits such as quality of life and reduction of clinical HF symptoms. Treatment of patients with HF with preserved ejection fraction displayed disappointing results from several large randomized controlled trials. The heterogeneity of HF with preserved ejection fraction, understood as complex syndrome, seems to be one of the primary reasons. Here, we present an overview of the current management strategies with available evidence and new therapeutic approach from drugs currently in clinical trials, which target diastolic dysfunction, chronotropic incompetence, and risk factor management. We provide an outline and interpretation of recent clinical trials that failed to improve outcome and survival in patients with HF with preserved ejection fraction.

关键词： Diastolic dysfunction Preserved ejection fraction

Covalent linkage of sulfated hyaluronan to the collagen scaffold Mucograft® enhances scaffold stability and reduces proinflammatory macrophage activation in vivo

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Bioactive Materials 2022年第2期7卷 420-434页

作者： Sarah Al-Maawi Sandra Rother Norbert Halfter Karen M.Fiebig Juliane moritz Stephanie Moeller Matthias Schnabelrauch Charles James Kirkpatrick Robert Sader Hans-peter Wiesmann Dieter Scharnweber Vera Hintze Shahram Ghanaati Clinic for Maxillofacial and Plastic Surgery Goethe UniversityFrankfurt Am MainGermany Institute of Materials Science Max Bergmann Center of BiomaterialsTU DresdenBudapester Str.2701069DresdenGermany Biomaterials Department INNOVENT e.V.Prüssingstr.27B07745JenaGermany Department of Cellular and Molecular Medicine Glycobiology Research and Training CenterUniversity of CaliforniaSan DiegoLa JollaCAUSA

Sulfated glycosaminoglycans(sGAG)show interaction with biological mediator *** collagen-based biomaterials are widely used in clinics,their combination with high-sulfated hyaluronan(sHA3)is *** study aims to functionalize a collagen-based scaffold(Mucograft®)with sHA3 via electrostatic(sHA3/PBS)or covalent binding to collagen fibrils(sHA3+EDC/NHS).Crosslinking without sHA3 was used as a control(EDC/NHS Ctrl).The properties of the sHA3-functionalized materials were *** vitro growth factor and cytokine release after culturing with liquid platelet-rich fibrin was performed by means of *** cellular reaction to the biomaterials was analyzed in a subcutaneous rat *** study revealed that covalent linking of sHA3 to collagen allowed only a marginal release of sHA3 over 28 days in contrast to electrostatically bound ***3+EDC/NHS scaffolds showed reduced vascular endothelial growth factor(VEGF),transforming growth factor beta 1(TGF-β1)and enhanced interleukin-8(IL-8)and epithelial growth factor(EGF)release in vitro compared to the other *** sHA3/PBS and EDC/NHS Ctrl scaffolds showed a high proinflammatory reaction(M1:CD-68+/CCR7+)and induced multinucleated giant cell(MNGC)formation in *** sHA3+EDC/NHS scaffolds reduced the proinflammatory macrophage M1 response and did not induce MNGC formation during the 30 ***3+EDC/NHS scaffolds had a stable structure in vivo and showed sufficient integration into the implantation region after 30 days,whereas EDC/NHS Ctrl scaffolds underwent marked disintegration and lost their initial *** summary,functionalized collagen(sHA3+EDC/NHS)modulates the inflammatory response and is a promising biomaterial as a stable scaffold for full-thickness skin regeneration in the future.

关键词： Sulfated hyaluronan Collagen Wound healing Cellular reaction Multinucleated giant cells

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PLATH软件无线电系统介绍

中国无线电 2007年第4期 63-64页

作者： peter moritz 薛宁地

1992年5月，Joe Mitola在美国通信系统会议上首次提出了软件无线电（soft radio）的概念，这是一个以现代通信理论为基础、以数字信号处理和宽频带技术为核心、以微电子技术为支撑的新型的无线电通信体系结构。也有人将其称为软件可定... 详细信息

1992年5月，Joe Mitola在美国通信系统会议上首次提出了软件无线电（soft radio）的概念，这是一个以现代通信理论为基础、以数字信号处理和宽频带技术为核心、以微电子技术为支撑的新型的无线电通信体系结构。也有人将其称为软件可定义的无线电（soft-defined radio）。这个新技术概念很快就引起了世界各国的注意。软件无线电技术的开发在最近十来年取得了引人注目的进展，引发了包括军事通信、个人移动通信、微电子以及计算机等电子学分支领域人士的普遍兴趣和极大热情。人们都认为，在未来的移动通信中，软件无线电将改变传统观念，在智能化、

关键词：软件无线电系统个人移动通信软件无线电技术宽频带技术微电子技术数字信号处理通信体系结构通信系统

Ruptured angiosarcoma of the liver treated by emergency catheter-directed embolization

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World Journal of Gastroenterology 2006年第5期12卷 804-808页

作者： Christine Leowardi Yura Hormann UIf Hinz moritz N Wente peter Hallscheidt Christa Flechtenmacher Markus W Büchler Helmut Friess Matthias HM Schwarzbach Department of Surgery University of HeidelbergIm Neuenheimer Feld 11069120 HeidelbergGermany Unit for Documentation and Statistics Department of SurgeryUniversity of HeidelbergIm Neuenheimer Feld 11069120 HeidelbergGermany Department of Radiology University of HeidelbergIm Neuenheimer Feld 11069120 HeidelbergGermany Institute of Pathology University of HeidelbergIm Neuenheimer Feld 22069120 HeidelbergGermany

Angiosarcoma is a rare primary malignant neoplasm of the liver with a poor prognosis. Here, we report a case of a patient with a ruptured hepatic angiosarcoma which was treated by emergency catheter-directed embolizat... 详细信息

关键词： Ruptured angiosarcoma Liver Embolization

Akt-RSK-S6-kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases

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Akt-RSK-S6-kinase Signaling Networks Activated by Oncogenic ...

“细胞活动生命活力”——中国细胞生物学学会全体会员代表大会暨第十二次学术大会

作者： Albrecht moritz Judit Villen Joan MacNeill Jon Kornhauser Kam Sprott Anthony Possemato peter Hornbeck Lewis C.Cantley Steven P.Gygi John Rush Michael J.Comb Cell Signaling Technology Inc.Danvers MA 01923 Department of Cell Biology Harvard Medical School BostonMA 02115 Departmcnt of Systems Biology Harvard Medical SchoolBeth Israel Deaconess Medical CenterBostonMA 2115

Receptor tyrosine kinases(RTKs) activate pathways mediated by Ser/Thr kinases such as the PI3K-Akt pathway,the Ras-MAPK-RSK pathway,and the mTOR-p70 s6 pathway that control important aspects of cell growth,proliferation,and *** Akt,RSK,and p70 s6 family of protein kinases transmit signals by phosphorylating substrates on a RxRxxS/T ***,we developed a large-scale proteomic approach to identify over 200 substrates of this kinase family in cancer cell lines driven by the c-Met,

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德国WakuWaku食品商店

现代装饰 2013年第7期 96-99页

作者： peter Ippolito Gunter Fleitz moritz Khler Michael Bertram Markus Schmidt Timo Flott WakuWaku Benjamin Nadjib 谢作标 Ippolito Fleitz Group

WaKuWaku定位为速食食品店和有机食品店的综合体后重新开张,这家食品店以＂有机＂和＂可持续发展＂作为核心经营理念,并且将此理念贯穿至室内空间的设计中。整个店铺兼用餐区几乎包裹着一层实木镶板,狭长的空间拥有宽敞、开放式的外墙,... 详细信息

WaKuWaku定位为速食食品店和有机食品店的综合体后重新开张,这家食品店以＂有机＂和＂可持续发展＂作为核心经营理念,并且将此理念贯穿至室内空间的设计中。整个店铺兼用餐区几乎包裹着一层实木镶板,狭长的空间拥有宽敞、开放式的外墙,不仅使过往行人能够清楚地看到食品店内部的场景,也为WakuWaku内部打造了理想的产品展示平台。

关键词：食品店商店德国室内空间可持续发展经营理念产品展示综合体

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探游意大利丝绸之都

疯狂英语（阅读版） 2009年第4期 38-42页

作者： peter Ross Range 左边

“蚕是一种势利的虫子，”莫里兹·曼特罗说，“它们可以吃任何东西，但是只有吃了桑叶才能吐丝f”曼特罗是意大利一家丝绸制品公司Mantero Seta SpA的第三代继承人，该公司是科摩市最大的丝绸制造商之一。科摩市坐落在意大利北部湖区... 详细信息

“蚕是一种势利的虫子，”莫里兹·曼特罗说，“它们可以吃任何东西，但是只有吃了桑叶才能吐丝f”曼特罗是意大利一家丝绸制品公司Mantero Seta SpA的第三代继承人，该公司是科摩市最大的丝绸制造商之一。科摩市坐落在意大利北部湖区，距离瑞士边境仅3英里。它为纽约、巴黎和附近的米兰的各大时装店提供丝绸制品。今天，在科摩及其附近的丘陵地带已有800家从事丝绸和其他纺织品贸易的公司，其业务涉及生产、印花、染色、设计和销售。如果你有某条丝巾领带，某件上衣外套是来自哪个著名时装店的，那它用的丝绸很有可能就来自科摩。

关键词：丝绸制品意大利纺织品贸易时装店公司继承人第三代 SpA

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大连国际会议中心

城市环境设计 2020年第4期 220-233页

作者：沃尔夫·狄·普瑞克斯 Nico Boyer Jan Brosch Jessie Chen Yue Chen Debora Creel Simon Diesendruck Pola Dietrich Wendy Fok Keigo Fukugaki Francois Gandon Alice Gong Reinhard Hacker Thomas Hindelang Veronika Janovska moritz Keitel Matt Kirkham Ariane Marx Gaspar Gonzalez Melero Matthias Niemeyer Reinhard Platzl Ian Robertson peter Rose Liisi Salumaa Anja Sorger Giacomo Tinari Vanessa Castro Vélez Markus Wings Hui-Cheng Manfred Yuen Cristiano Bianchi Duccio Malagamba ShuHe COOP HIMMELB(L)AU Markus Pillhofer

项目大事记/CHRONOLOGY竞赛/Competition:03/2008规划设计/Start of Planning:07/2008动工/Start of Construction:11/2008竣工/Completion:09/2012项目参数/PROJECT DATA用地面积/Site Area:40 000m2会议中心总建筑面积/Gross Floor Area Conference Center:91 250m2,总建筑面积/Total:146 180m2占地面积/Footprint:33 000m2表皮面积/Fa?ade Area:30 600m2屋顶面积/Roof area:28 000m2建筑高度-长度-宽度/Building Height-Length-Width:60m-220m-200m层数/Number of Floors:8

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“黑白分明”的美国家庭财富状况

商业周刊（中文版） 2019年第8期 71-71页

作者： peter Coy 汪泽(译) 不详

对于美国黑人和白人收入及财富差距,最卓越的研究来自德国。波恩大学(University of Bonn)经济学家莫里兹.库恩(Moiritz Kuhn)、莫里兹.舒拉克(moritz Schularick)和乌里克.施泰因(Ulrike Steins)收集了美联储消费者财务状况调查(Survey... 详细信息

对于美国黑人和白人收入及财富差距,最卓越的研究来自德国。波恩大学(University of Bonn)经济学家莫里兹.库恩(Moiritz Kuhn)、莫里兹.舒拉克(moritz Schularick)和乌里克.施泰因(Ulrike Steins)收集了美联储消费者财务状况调查(Survey of Consumer Finances)从1949年至2016年的历史数据,从家庭而非个人角度岀发分析了所有收入来源。

关键词：家庭财富美国收入来源 1949年财富差距经济学家财务状况历史数据