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j.urnal of Materials Science & Technology 2021年第9期68卷 70-75页

作者： j.a Li Baobin Xie Qihong Fang Bin Liu Yong Liu peter k.Liawc State key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha410082.China State key Laboratory of Powder Metallurgy.Central South University Changsha410083China Department of Materials Science and Engineering The University of TennesseeKnoxvilleTN37996USA

In medium/high entropy alloys, their mechanical properties are strongly dependent on the chemicalelemental composition. Thus, searching for optimum elemental composition remains a critical issue to maximize the mechanical performance. However, this issue solved by traditional optimization process via "trial and error" or experiences of domain experts is extremely difficult. Here we propose an approach based on high-throughput simulation combined machine learning to obtain medium entropy alloys with high strength and low cost. This method not only obtains a large amount of data quickly and accurately,but also helps us to determine the relationship between the composition and mechanical *** results reveal a vital importance of high-throughput simulation combined machine learning to find best mechanical properties in a wide range of elemental compositions for development of alloys with expected performance.

关键词： Medium entropy alloy Optimum elemental composition High-throughput simulation Machine learning

Whatever happened to China’s neglected tropical diseases?

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Infectious Diseases of Poverty 2019年第5期8卷 1-3页

作者： peter j.Hotez Texas Children's Hospital Center for Vaccine Development Departments of Pediatrics and Molecular Virology&MicrobiologyNational School of Tropical MedicineBaylor College of MedicineHoustonTXUSA Hagler Institute for Advanced Studies at Texas A&M University College StationTXUSA Department of Biology Baylor UniversityWacoTXUSA j.mes A Baker III Institute of Public Policy Rice UniversityHoustonTXUSA Scowcroft Institute of International Affairs Texas A&M UniversityCollege StationTXUSA

Before the founding of the People's Republic of China 70 years ago,both extreme poverty and parasitic infections and other neglected tropical diseases were highly *** to social development,particularly economic reforms since the 1980s,poverty has since been dramatically reduced,and China became increasingly urbanized and *** parallel,China's economic transformation translated into similar and remarkable reductions in neglected tropical *** and colleagues report in their review published in Infectious Diseases of Poverty,the elimination or near elimination as a public health problem of lymphatic filariasis,trachoma,soil-transmitted helminth infections,schistosomiasis and other neglected tropical *** note,neglected tropical disease control and poverty reduction each appear to reinforce the ***'s formula for success in parasitic and neglected tropical disease control might translate to other parts of the world,such as in sub-Saharan Africa through China's new Belt and Road Initiative.

关键词： Control Elimination Neglected tropical diseases Parasitic infections People's Republic of China Poverty reduction

Claudin-11 and occludin are maj.r contributors to Sertoli cell tight j.nction function, in vitro

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Asian j.urnal of Andrology 2016年第4期18卷 620-626页

作者： Mark j.McCabe Caroline FH Foo Marcel E Dinger peter M Smooker peter G Stanton Male Fertility Regulation Laboratory Hudson Institute of Medical Research Monash Medical Centre Clayton Victoria 3168 Australia School of Applied Sciences Royal Melbourne Institute of Technology University Bundoora Victoria 3088 Australia kinghorn Centre for Clinical Genomics Garvan Institute of Medical Research Darlinghurst New South Wales 2010 Australia St Vincent's Clinical School UNSW Sydney New South Wales 2052 Australia.

The Sertoli cell tight j.nction （T j. is the key component of the blood-testis barrier, where it sequesters developing germ cells undergoing spermatogenesis within the seminiferous tubules. Hormonally regulated claudin-11 is a critical transmembrane protein involved in barrier function and its murine knockout results in infertility. We aimed to assess quantitatively the significance of the contribution of claudin-11 to Tj.function, in vitro, using siRNA-mediated gene silencing. We also conducted an analysis of the contribution of occludin, another intrinsic transmembrane protein of the Tj. Silencing of claudin-11 and/or occludin was conducted using siRNA in an immature rat Sertoli cell culture model. Transepithelial electrical resistance was used to assess quantitatively Tj.function throughout the culture. Two days after siRNA treatment, cells were fixed for immunocytochemical localization of j.nction proteins or lyzed for RT-PCR assessment of mRNA expression. Silencing of claudin-11, occludin, or both resulted in significant decreases in Tj.function of 55% （P 〈 0.01）, 51% （P 〈 0.01）, and 62% （P 〈 0.01）, respectively. Data were concomitant with significant decreases in mRNA expression and marked reductions in the localization of targeted proteins to the Sertoli cell Tj. We provide quantitative evidence that claudin-11 contributes significantly （P 〈 0.01） to Sertoli cell Tj.function in vitro. Interestingly, occludin, which is hormonally regulated but not implicated in infertility until late adulthood, is also a significant （P 〈 0.01） contributor to barrier function. Our data are consistent with in vivo studies that clearly demonstrate a role for these proteins in maintaining normal Tj.barrier structure and function.

关键词： blood-testis barrier claudin-11 occludin Sertoli cell tight j.nction siRNA

Guest Editorial:Special Section on Active Distribution Networks:Markets,Operations,Planning,and Regulation

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j.urnal of Modern Power Systems and Clean Energy 2023年第1期11卷 1-2页

作者： peter Palensky Qixin Chen Marcos j.Rider Delft University of Technology DelftNetherlands Tsinghua University BeijingChina University of Campinas Sao PauloBrazil

THE power system is in change,and the most fundamental changes are happening in the distribution *** passive consumers get active and smart,energy storage and distributed generation appears,and the“grid edge”is upgraded with Intenet of Things(IoT).Gone are the days where distribution infrastructure consisted of passive assets,dimensioned for the worst case of load.

关键词： passive IoT distribution

Using Inductance as a Tuning Parameter for RF Meta-atoms

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Nano-Micro Letters 2012年第2期4卷 103-109页

作者： Derrick Langley Ronald A.Coutu peter j.Collins Air Force Institute of Technology Wright-Patterson Air Force Base

The resonant frequency of metamaterials structured with split ring resonator(SRR) meta-atoms is determined primarily through the capacitance and inductance of the individual meta-atoms. Two designs that vary inductance incrementally were modeled, simulated, fabricated, and tested to investigate the role inductance plays in metamaterial designs. The designs consisted of strategically adding sections to the SRR to increase the inductance, but in a manner that minimized capacitance variations. Each design showed a shift in resonant frequency that was proportional to the length of the added section. As the length of each section was increased, the resonant frequency shifted from 2.78 GHz to 2.18 GHz.

关键词： Inductance Meta-atom Metamaterial Split Ring Resonator Radio Frequency Resonance

Variability in total cost of vehicle ownership across vehicle and user profiles

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Communications in Transportation Research 2022年第1期2卷 206-221页

作者： Yulu Guo j.Andrew kelly j.peter Clinch UCD Environmental Policy University College DublinRichviewClonskeaghIreland EnvEcon Decision Support 11 Priory Office ParkBlackrockDublinIreland UCD Earth Institute and UCD Geary Institute for Public Policy BelfieldDublin4Ireland

Widespread adoption of electric vehicles(EVs)is a common and critical component of international strategies to mitigate environmental pollution,climate change and oil *** ability of consumers to assess the total cost of ownership(TCO)of EVs relative to internal combustion engine vehicles(ICEVs)remains an important factor for EV *** TCO of vehicles is not universal across different car segments and user *** analyse and compare the TCO of ICEVs and EVs from 17 car segments across short-and long-term ownership periods,and further advance existing TCO approaches by integrating detailed activity-based driving profiles,taxation,grant structures and *** show that EV options in the most popular Irish car segments have existing battery EV options with a TCO averaging respectively 26% and 42% less than their equivalent petrol and diesel ICEV options over a 4-year ownership term when the current grant is *** integrated method for granular TCO evaluation offers important insights for this market and affords scope to investigate how changes in travel patterns,car-segment pricing,taxation,grant policy,fuel costs,and carbon pricing and other transport policies can all affect TCO values over time across a broad range of market offerings.

关键词： Total cost of ownership Electric vehicles(EVs) Driving profile Car segments Depreciation cost Transport Climate policy

Mini-review on edible mushrooms as source of dietary fiber:Preparation and health benefits

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Food Science and Human Wellness 2013年第3期2卷 162-166页

作者： peter C.k.Cheung Food and Nutritional Sciences School of Life SciencesThe Chinese University of Hong KongHong KongChina

Dietary fiber and high-fiber food products have attracted great attention because of their significant health benefits to *** are valuable resources for food,medicine and *** mushroom is considered as a novel source of dietary *** dietary fiber content and composition in edible mushroom vary greatly with its morphological stages including fruit body,mycelium and *** focus of this mini-review is on the preparation of dietary fiber from edible mushroom with emphasis on the sclerotium which has the highest level of non-starch *** possible health benefits of mushroom dietary fiber in relationship with boosting the immune system,anticancer functions as well as the control of blood lipids and glucose levels are also discussed.©2013 Beij.ng Academy of Food *** and hosting by Elsevier *** rights reserved.

关键词： Dietary fiber Edible mushrooms Health benefits Preparation

High-quality-factor tantalum oxide nanomechanical resonators by laser oxidation of TaSe2

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Nano Research 2015年第9期8卷 2842-2849页

作者： Santiago j. CartamiI-Bueno peter G. Steeneken Frans D. Tichelaar Efren Navarro-Moratalla Warner j. Venstra Ronald van Leeuwen Eugenio Coronado Herre S.j. van der Zant Gary A. Steele Andres Castellanos-Gomez kavli Institute of Nanoscience Delft University of Technology Lorentzweg 1 2628 CJ Delft The Netherlands kavli Institute of Nanoscience Delft University of Technology National Centre for HREM Lorentzweg 1 2628 CJ Delft The Netherlands Instituto Ciencia Molecular (ICMol) Univ. Valencia C/Catedrdtico Jos@ Beltrdn 2 E-46980 Paterna Spain

Controlling the strain in two-dimensional （2D） materials is an interesting avenue to tailor the mechanical properties of nanoelectromechanical systems. Here, we demonstrate a technique to fabricate ultrathin tantalum oxide nanomechanical resonators with large stress by the laser oxidation of nano-drumhead resonators composed of tantalum diselenide （TaSe2）, a layered 2D material belonging to the metal dichalcogenides. Before the study of their mechanical properties with a laser interferometer, we verified the oxidation and crystallinity of the freely suspended tantalum oxide using high-resolution electron microscopy. We demonstrate that the stress of tantalum oxide resonators increases by 140 MPa （with respect to pristine TaSe2 resonators）, which causes an enhancement in the quality factor （14 times larger） and resonance frequency （9 times larger） of these resonators.

关键词： TaSe2,tantalum oxide,mechanical resonators,laser oxidation,optical interferometer,high quality factor

Effect of oxygen and nitrogen functionalization on the physical and electronic structure of graphene

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Nano Research 2015年第8期8卷 2620-2635页

作者： Alexander j. Marsden peter Brommer j.mes j. Mudd M. Adam Dyson Robert Cook Maria Asensio j.se Avila Ana Levy j.remy Sloan David Quigley Gavin R. Bell Neil R. Wilson Department of Physics University of Warwick Coventry UK Centre for Scientific Computing University of Warwick Coventry UK Synchrotron SOLEIL L'Orme des Merisiers Saint Aubin-BP 48 91192 Gifsur Yvette Cedex France

Covalent functionalization of graphene offers opportunities for tailoring its properties and is an unavoidable consequence of some graphene synthesis techniques. However, the changes induced by the functionalization are not well understood. By using atomic sources to control the extent of the oxygen and nitrogen functionalization, we studied the evolution in the structure and properties at the atomic scale. Atomic oxygen reversibly introduces epoxide groups whilst, under similar conditions, atomic nitrogen irreversibly creates diverse functionalities including substitutional, pyridinic, and pyrrolic nitrogen. Atomic oxygen leaves the Fermi energy at the Dirac point （i.e., undoped）, whilst atomic nitrogen results in a net n-doping; however, the experimental results are consistent with the dominant electronic effect for both being a transition from delocalized to localized states, and hence the loss of the signature electronic structure of graphene.

关键词： graphene functionalization chemical vapor deposition density functional theory

Light-emitting self-assembled metallacages

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National Science Review 2021年第6期8卷 94-111页

作者： j.n Zhao Zhixuan Zhou Guangfeng Li peter j.Stang Xuzhou Yan School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong University Department of Chemistry University of Utah

Coordination-driven self-assembly of metallacages has garnered significant interest because of their 3 D layout and cavity-cored nature. The well-defined, highly tunable metallacage structures render them particularly attractive for investigating the properties of luminophores, as well as for inducing novel photophysical characters that enable widespread applications. In this review, we summarize the recent advances in synthetic methodologies for light-emitting metallacages, and highlight some representative applications of these metallacages. In particular, we focus on the favorable photophysical properties—including high luminescence efficiency in various physical states, good modularity in photophysical properties and stimulus responsiveness—that have resulted from incorporating ligands displaying aggregation-induced emission(AIE) into metallacages. These features show that the synergy between carrying out coordination-driven self-assembly and using luminophores with novel photophysical characteristics like AIE could stimulate the development of supramolecular luminophores for applications in fields as diverse as sensing, biomedicine and catalysis.

关键词： supramolecular coordination complexes coordination-driven self-assembly aggregation-induced emission metallacages organometallic materials