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Prunus genetics and applications after de novo genome sequencing:achievements and prospects

Horticulture Research 2019年第1期6卷 1222-1246页

作者： Maria JoséAranzana Véronique Decroocq Elisabeth Dirlewanger Iban Eduardo Zhong Shan Gao Ksenija Gasic Amy Iezzoni Sook Jung Cameron Peace Humberto Prieto Ryutaro Tao Ignazio Verde Albert G.Abbott pere Arús IRTA Centre de Recerca en Agrigenòmica CSIC-IRTA-UAB-UBCampus UABEdifici CRAGCerdanyola del Vallès(Bellaterra)08193 BarcelonaSpain UMR 1332 BFP INRAUniversity of BordeauxA3C and Virology Teams33882 Villenave-d’Ornon CedexFrance Allergy Research Center Zhejiang University310058 HangzhouChina Clemson University ClemsonSC 29634USA Department of Horticulture Michigan State University1066 Bogue StreetEast LansingMI 48824-1325USA Department of Horticulture Washington State UniversityPullmanWA 99164-6414USA Biotechnology Laboratory La Platina Research StationInstituto de Investigaciones AgropecuariasSanta Rosa11610 La PintanaSantiagoChile Laboratory of Pomology Graduate School of AgricultureKyoto UniversityKyoto 606-8502Japan Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria(CREA)-Centro di ricerca Olivicoltura Frutticoltura e Agrumicoltura(CREA-OFA)RomeItaly University of Kentucky 106 T.P.Cooper HallLexingtonKY 40546-0073USA

Prior to the availability of whole-genome sequences,our understanding of the structural and functional aspects of Prunus tree genomes was limited mostly to molecular genetic mapping of important traits and development of EST *** public release of the peach genome and others that followed,significant advances in our knowledge of Prunus genomes and the genetic underpinnings of important traits *** this review,we highlight key achievements in Prunus genetics and breeding driven by the availability of these whole-genome *** the structural and evolutionary contexts,we summarize:(1)the current status of Prunus whole-genome sequences;(2)preliminary and ongoing work on the sequence structure and diversity of the genomes;(3)the analyses of Prunus genome evolution driven by natural and man-made selection;and(4)provide insight into haploblocking genomes as a means to define genome-scale patterns of evolution that can be leveraged for trait selection in pedigree-based Prunus tree breeding programs ***,we summarize recent and ongoing work that leverages whole-genome sequences to identify and characterize genes controlling 22 agronomically important Prunus *** include phenology,fruit quality,allergens,disease resistance,tree architecture,and ***,we explore the application of sequence-based marker-assisted breeding technologies and other sequence-guided biotechnological approaches for Prunus crop ***,we present the current status of publically available Prunus genomics and genetics data housed mainly in the Genome Database for Rosaceae(GDR)and its updated functionalities for future bioinformatics-based Prunus genetics and genomics inquiry.

关键词： Prunus breeding achievements

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废石堆上的公园——旧焦炭堆Drocourt的景观修复设计

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城市环境设计 2007年第5期 78-83页

作者：奎瑞·佩雷路景晴

"昨天,这个城市还是以工厂为背景。今天将把它从黑色完全变为绿色。这个公园是真正意义上的城市化改造的一个重要元素。"法国ILEX景观与城市规划设计公司董事长佩雷(pere)先生在一次媒体采访中给出了对整个项目的定位。在2005年的一次... 详细信息

"昨天,这个城市还是以工厂为背景。今天将把它从黑色完全变为绿色。这个公园是真正意义上的城市化改造的一个重要元素。"法国ILEX景观与城市规划设计公司董事长佩雷(pere)先生在一次媒体采访中给出了对整个项目的定位。在2005年的一次公开招标中,ILEX公司以其生态的设计理念和可持续性的规划方案从众多的优秀方案中脱颖而出,赢得了所有评委和当地居民的肯定,最终一举中标。

关键词：公园法国园林法兰西共和国城市规划设计 Drocourt 固体燃料焦炭

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时·光旅行

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现代装饰（家居） 2015年第10期 62-67页

作者： Aij Kaldanova Moshi-mosh Alexandre Boucher Jakub Krakovsky Kjartan Oskarsson Michael Anastassiades pere Selles Alessio Romano Gorjup Design Nikodem Szpunar 李薇范嘉苑 Presek Design Studio Richard Clarkson Studio

时间总在不经意间从指缝中滑落,从我们身边悄悄地溜走,让我们措手不及,正如哲人高尔基所说：世界上最快而又最慢,最长而又最短,最平凡而又最珍贵,最易被忽视而又最令人后悔的就是时间。虽然我们无法用言语来描述出时间的形状,但它却实... 详细信息

时间总在不经意间从指缝中滑落,从我们身边悄悄地溜走,让我们措手不及,正如哲人高尔基所说：世界上最快而又最慢,最长而又最短,最平凡而又最珍贵,最易被忽视而又最令人后悔的就是时间。虽然我们无法用言语来描述出时间的形状,但它却实实在在地走在这个世界上,也许时钟的滴答声最能代表它的脚步。而当时钟的指针走到特定的位置,夜幕也就悄然降临,灯光开始逐渐亮起,万家灯火,每一个窗口处的灯光都有着一种心情,或是等待,或是守候,或是陪伴,让人倍感温暖。

关键词：这个世界几何造型发光体设计原型激光切割塑料材质片层灯架生活空间圆柱形

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西班牙:装饰涂料市场

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中国涂料 2005年第10期20卷 48-48页

作者： José Farres pere Indústrias Titan Spain

在西班牙,有不少于500家不同规模的从事装饰涂料生产的涂料厂.它们当中大约90%只生产水性涂料,而且它们的影响是地域性的(大概在以它们工厂为圆心、50km为半径的范围内).从市场看,即使它们的营业额低,但当它们在各自的地区确立了竞争地... 详细信息

在西班牙,有不少于500家不同规模的从事装饰涂料生产的涂料厂.它们当中大约90%只生产水性涂料,而且它们的影响是地域性的(大概在以它们工厂为圆心、50km为半径的范围内).从市场看,即使它们的营业额低,但当它们在各自的地区确立了竞争地位之后,这全部的产出量是相当重要的,并且它们对大公司的市场政策有重要的影响.

关键词：涂料市场西班牙装饰涂料生产水性涂料涂料厂地域性营业额产出量

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Pedigree analysis of 220 almond genotypes reveals two world mainstream breeding lines based on only three different cultivars

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Horticulture Research 2021年第1期8卷 72-82页

作者： Felipe perez de los Cobos Pedro J.Martinez-Garcia Agusti Romero Xavier Miarnau Iban Eduardo Werner Howad Mourad Mnejja Federico Dicenta Rafel Socias i Company Maria J.Rubio-Cabetas Thomas M.Gradziel Michelle Wirthensohn Henri Duval Doron Holland pere Arus Francisco J.Vargas Ignasi Batlle Institut de Recerca i Tecnologia Agroalimentaries(IRTA) Mas BoveCtra.Reus-El Morell Km 3843120 ConstantiTarragonaSpain Institut de Recerca i Tecnologia Agroalimentaries(IRTA) Centre de Recerca en Agrigenomica(CRAG)CSIC-IRTA-UAB-UB.Cerdanyola del Valles(Bellaterra)08193 BarcelonaSpain Centro de Edafologia y Biologia Aplicada del Segura Consejo Superior de Investigaciones Cientificas(CEBAS-CSIC)P.O.Box 16430100 EspinardoMurciaSpain Institut de Recerca i Tecnologia Agroalimentaries(IRTA) FruitcentrePCiTALGardeny ParkFruitcentre Building25003 LleidaSpain Centro de Investigacion y Tecnologia Agroalimentaria de Aragon(CITA) Avda.Montanana 93050059ZaragozaInstituto Agroalimentario de Aragon IA2(CITA-Universidad de Zaragoza)ZaragozaSpain University of California 1 Shields AvenueDavisCA 95616USA University of Adelaide Waite ResearchSchool of AgricultureFood and WinePMB 1Glen OsmondAdelaideSA 5064Australia Institut National de la Recherche Agronomique(INRA) Domain St.Maurice CS 6009484143 Montfavet CedexFrance Agricultural Research Organization Newe-Ya’ar Research CenterP.O.Box 1021Ramat Yishad 30095Israel

Loss of genetic variability is an increasing challenge in tree breeding programs due to the repeated use of a reduced number of founder ***,in almond,little is known about the genetic variability in current breeding stocks,although several cases of inbreeding depression have been *** gain insights into the genetic structure in modern breeding programs worldwide,marker-verified pedigree data of 220 almond cultivars and breeding selections were *** coefficients,pairwise relatedness,and genetic contribution were calculated for these *** results reveal two mainstream breeding lines based on three cultivars:“Tuono”,“Cristomorto”,and“Nonpareil”.Descendants from“Tuono”or“Cristomorto”number 76(sharing 34 descendants),while“Nonpareil”has 71 *** mean inbreeding coefficient of the analyzed genotypes was 0.041,with 14 genotypes presenting a high inbreeding coefficient,over *** programs from France,the USA,and Spain showed inbreeding coefficients of 0.075,0.070,and 0.037,*** to their genetic contribution,modern cultivars from Israel,France,the USA,Spain,and Australia trace back to a maximum of six main founding *** the group of 65 genotypes carrying the S f allele for self-compatibility,the mean relatedness coefficient was 0.125,with“Tuono”as the main founding genotype(24.7%of total genetic contribution).The results broaden our understanding about the tendencies followed in almond breeding over the last 50 years and will have a large impact into breeding decision-making process *** current genetic variability is required in almond breeding programs to assure genetic gain and continuing breeding progress.

关键词： breeding cultivar founding

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李属过敏原蛋白家族的基因组特征及其与苹果属的同一性分析

李属过敏原蛋白家族的基因组特征及其与苹果属的同一性分析

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中国园艺学会十届二次理事会暨学术研讨会

作者：陈琳高中山宋丽娟张水明 Eudald Illa Werner Howad Eric van de Weg pere Arus 陈昆松浙江大学果树科学研究所

蔷薇科许多李属水果如桃,李子,樱桃和杏在国际上经常被报道为重要的食物过敏来源,以往研究表明,鲜食水果过敏性程度因种和品种而异,通过育种手段可以选择低或无过敏性的新品种。开展育种工作首先需要了解过敏基因成员、连锁图谱定位和...

蔷薇科许多李属水果如桃,李子,樱桃和杏在国际上经常被报道为重要的食物过敏来源,以往研究表明,鲜食水果过敏性程度因种和品种而异,通过育种手段可以选择低或无过敏性的新品种。开展育种工作首先需要了解过敏基因成员、连锁图谱定位和相关遗传标记。根据目前临床医学和

关键词：

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Structural and Electrical Characterization of PbS： Ni Nanocrystallites Synthesized by Chemical Bath Deposition

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材料科学与工程（中英文A版） 2013年第2期3卷 92-103页

作者： Melissa Chaivez Portillol Rene. Gutierrez pere Mois6s Araiza Garcia Marcial Zamora Tototzintle Andres Facultad de Ciencias Qulmicas Benem~rita Universidad Aut6noma de Puebla C. U. Puebla 72001 Pue. Mexico Lab. Sintesis de Complejos Facultad de Ciencias Qulmicas Benem~rita Universidad Aut6noma de Puebla Puebla 72001 Pu~.M~xico ITESM Campus Puebla Via Atlixcayoti 2301 Colonia Reserva Territorial Atlixcayolt C.P. 72453 Mexico

The growth of nanocrystalline PbS films by chemical bath deposition (CBD) onto glass at a deposition temperature of 20 ± 2 °C is reported. Different doping levels were obtained by changing the volume of the reagent solution V[Ni2+] into the PbS growing solution were added. X-ray diffraction (XRD), Transmssion Microscopy Electronic (TEM), Raman spectroscopy (RS), dark conductivity (DC) measurements was carried out to characterize the PbS films. XRD spectra displayed peaks at the angular positions: 2θ = (26.00, 30.07, 43.10, 51.00, 53.48), indicating growth on the zinc blende face. The grain size (GS) determined by x-rays diffraction of the undoped samples, was found to be ~36 nm, whereas with the doped sample is found to be in the range ~32-5 nm, as calculated by employing Scherer"s formula. By TEM, the doped-PbS materials were found crystalline films in the range 3.5-5 nm. RS exhibited band centred at ~135 cm-1 displaying only a PbS ZB structure, excluding the presence of any other material. The thermal energy for the films was determined from the slope of DC and the energy was estimated to be 0.15 to 0.5 eV. Finally, Gibbs free energy calculation for the V[Ni2+] doping-PbS process was also established.

关键词：纳米晶结构化学浴沉积 PBS 电气特性透射电子显微镜 X-射线衍射 X射线衍射光谱合成

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Can Ricart体育综合体

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建筑技艺 2010年第11期16卷 126-131页

作者： pere Buil Castells Jordi Fornells Castelló Manuel Arguijoy Asociados Carles Bima Puig Filipe Araújo Ricardo Borges Arnau Boronat Rubén Heras Sónia Bom Iigo Ribera Sónia Gaspar Adrià Goula 吴春花 vora arquitectura

Can Ricart体育俱乐部综合体位于一个历史上曾经一度萧条的区域,但该区域近年来发生了很大的变化.因此综合体的建设将对周边建筑的再生起到非常重要的作用,而且通过体育活动的运营也有助于区域与整个社会层的整合.

关键词：建筑立面游泳池水池阳极电镀 Can Ricart 建筑内部空间体育

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人类生命早期暴露组(HELIX)：项目理念与设计(待续)

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环境与职业医学 2015年第1期32卷 90-95页

作者： Martine Vrijheid Rémy Slama Oliver Robinson Leda Chatzi Muireann Coen Peter van den Hazel Cathrine Thomsen John Wright Toby J.Athersuch Narcis Avellana Xavier Basagana Celine Brochot Luca Bucchini Mariona Bustamante Angel Carracedo Maribel Casas Xavier Estivill Lesley Fairley Diana van Gent Juan R.Gonzalez Berit Granum Regina Grazuleviiene Kristine B.Gutzkow Jordi Julvez Hector C.Keun Manolis Kogevinas Rosemary R.C.McEachan Helle Margrete Meltzer Eduard Sabidó pere.Schwarze Valérie Siroux Jordi Sunyer Elizabeth J.Want Florence Zeman Mark J.Nieuwenhuijsen 何蓉操仪汪源金泰廙 Centre for Research in Environmental Epidemiology(CREAL) Universitat Pompeu Fabra(UPF) CIBER Epidemiología y Salud Pública(CIBERESP) Institut National de la Santé et de la Recherche Médicale(INSERM) Institut Albert Bonniot(U823) University of Crete(UOC) Imperial College London(ICL) Veiligheids-en Gezondheidsregio Gelderland Midden(VGGM) Norwegian Institute of Public Health(NIPH) Bradford Institute for Health Research Bradford Teaching Hospitals NHS Foundation Trust(BTHFT) Sensing & Control Systems S.L(.S&C) Institut National de l’Environnement Industriel et des Risques(INERIS) Unit of Models for Ecotoxicology and Toxicology Hylobates Consulting S.R.L(.HYLO) Centre for Genomic Regulation(CRG) IMIM Hospital del Mar Research Insititute Grupo de Medicina Xenomica Fundación Pública Galega de Medicina Xeómica(SERGAS)CIBERERCEGENUniversidade de Santiago de Compostela Center of Excellence in Genomic Medicine Research King Abdulaziz University Vytauto Didziojo Universitetas(VDU)

[背景]人类在生命早期的发育期间可能特别容易受到环境暴露的影响。有关这一主题的人体研究一般集中在单一暴露与健康效应之间的关系。而"暴露组"的概念涵盖了从受孕开始的的全部暴露,完善了基因组。[目的]人类生命早期暴露组(HELIX)项... 详细信息

[背景]人类在生命早期的发育期间可能特别容易受到环境暴露的影响。有关这一主题的人体研究一般集中在单一暴露与健康效应之间的关系。而"暴露组"的概念涵盖了从受孕开始的的全部暴露,完善了基因组。[目的]人类生命早期暴露组(HELIX)项目是一个新的合作研究项目,目的是为了采用新的暴露评估和生物标志分析方法来描述生命早期多种环境因素的暴露,并将这些与生物标志组学和儿童健康结局相关联,从而刻画"生命早期暴露组"。本文描述了该项目的总体设计。[方法]HELIX将利用欧洲现有的6个出生队列研究来估计产前、产后暴露的一系列化学和物理暴露。建立全部队列中总共32 000对母亲和儿童的暴露模型,并在一个包含1 200对母亲和儿童的子队列中测量生物标志。嵌套重复采样的定组研究(n=150)将收集生物标志的变化数据,利用智能手机来评估流动性和体力活动,并监测个体暴露。采用组学技术确定与暴露相关的分子学特征(代谢组、蛋白质组、转录组和表观基因组)。对于多次暴露,采用统计方法估计胎儿和儿童的成长、肥胖、神经发育和呼吸系统结局中的暴露-效应关系。项目还将进行一项健康效应评估测试,以评价组合暴露的风险和收益。[结论]HELIX是描述欧洲人群生命早期暴露组并解开它与组学标志物和儿童健康之间关联的首次尝试之一。作为对暴露组学这一概念的验证,该项目向生命过程中暴露组迈出了重要的第一步。

关键词：人类生命早期暴露设计出生队列研究儿童健康生物标志效应评估生命早期

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Observatory science with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 97-138页

作者： Jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-Luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi Frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares Francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig SRON Netherlands Institute for Space Research Department of Astronomy University of Geneva Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences School of Astronomy and Space Science Nanjing University INAF-IASF Bologna ASI Via del Politecnico snc INAF-Istituto di Astrofisica e Planetologie Spaziali Institut für Astronomie und Astrophysik Tübingen Universit?t Tübingen NASA Goddard Space Flight Center ICREA&Institute of Space Sciences(IEEC-CSIC) Campus UABCarrer de Can Magrans CSPAR SPA University of Alabama in Huntsville Department of Physics Texas Tech University INAF Osservatorio Astronomico di Capodimonte Leiden Observatory Leiden University Anton Pannekoek Institute University of Amsterdam ASTRON Netherlands Institute for Radio Astronomy Universitat Politecnica de Catalunya(UPC-IEEC) Universitádegli Studi di Urbino‘Carlo Bo’ Max-Planck-Institut für Radioastronomie Dr.Karl-Remeis-Sternwarte and Erlangen Centre for Astroparticle Physics(ECAP) Friedrich Alexander Universit?t Erlangen-Nurnberg Purple Mountain Observatory Chinese Academy of Sciences Instituto de Astrofysíca de Andalucia-CSIC Department of Physics and Astronomy University of Southampton IRAP Universitéde ToulouseCNRSUPSCNES Mathematical Sciences and STAG Research Centre University of Southampton New York University Abu Dhabi Center for Relativistic Astrophysics School of PhysicsGeorgia Institute of Technology Physics Department Middle East Technical University Department of Physics Technion-Israel Institute of Technology INAF Osservatorio Astronomico di Brera Tata Institute of Fundamental Research Dipartimento di Matematica e Fisica Universitàdegli Studi Roma Tre Instituto de Astrofísica de Canarias Instituto Nacional de Pesquisas Espaciais-INPE National Space Institute Technical University of Denmark(DTU Space) Department of Physics and Astronomy Michigan State University INAF Osservatorio Astrofisico di Arcetri Dipartimento di Fisica Universitádegli Studi di Cagliari Department of Physics and A

In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s.

关键词： space research in struments nuclear astrophysics flare stars accretion and accretion disks mass loss and stellar winds cataclysmic binaries X-ray binaries supernova remnants active galactic nuclei X-ray bursts gamma-ray bursts gravitational waves

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