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清代皖江救生事业与地方社会建构

近代史学刊 2024年第1期 198-217,295页

作者：李鹏鑫余涛安徽大学历史学院民政部培训中心

救生船作为清代皖江一项传统公益事业,受险滩、水流等自然因素及经济水平、水上交通等社会因素影响,主要分布在沿江一带;顺治朝到乾隆朝,从以往孤立分散的特性演变为国家权力主导,地方社会参与的形态。嘉道以降,受国力衰退及战乱影响,... 详细信息

救生船作为清代皖江一项传统公益事业,受险滩、水流等自然因素及经济水平、水上交通等社会因素影响,主要分布在沿江一带;顺治朝到乾隆朝,从以往孤立分散的特性演变为国家权力主导,地方社会参与的形态。嘉道以降,受国力衰退及战乱影响,国家权力主导的皖江救生船事业逐渐衰落,救生船经费及人员薪资等渐由地方社会力量多方筹措。迨至晚清,以官绅商为代表的地方社会精英群体,在皖江救生船的经费收支和人员管理上相互依赖、互为补充,最终呈现出官督绅办的模式。在这一过程中,国家和地方社会力量此消彼长,在支配和调动地方社会资源上出现显著变化。皖江救生船融入地方社会并形成“权力的文化网络”,从地方精英、民间组织、民间信仰等方面对地方社会进行建构,折射出清代以来国家权力的盛衰与地方社会格局的演变。

关键词：清代皖江救生船地方社会

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舒更葡糖钠对胸腔镜肺切除术后恢复的影响

临床麻醉学杂志 2024年第6期40卷 581-586页

作者：仇蕾夏肇敏黄茜李彭欣王玉东宋田皓辜晓岚顾连兵徐州医科大学麻醉学院 221004 江苏省肿瘤医院麻醉科

目的探讨舒更葡糖钠对胸腔镜肺切除术后肺部并发症(PPCs)及术后恢复的影响。方法选择2021年11月至2023年7月接受择期胸腔镜肺段切除术或肺叶切除术的患者263例,男112例,女151例,年龄18~64岁,BMI 18.5~28.0 kg/m^(2),ASAⅠ—Ⅲ级。将患... 详细信息

目的探讨舒更葡糖钠对胸腔镜肺切除术后肺部并发症(PPCs)及术后恢复的影响。方法选择2021年11月至2023年7月接受择期胸腔镜肺段切除术或肺叶切除术的患者263例,男112例,女151例,年龄18~64岁,BMI 18.5~28.0 kg/m^(2),ASAⅠ—Ⅲ级。将患者随机分为三组:舒更葡糖钠组(S组,n=88)、新斯的明组(N组,n=87)和对照组(C组,n=88)。患者术后被送至PACU,当四个成串刺激(TOF)计数为2时,S组静脉注射舒更葡糖钠2 mg/kg,N组静脉注射新斯的明0.04 mg/kg+阿托品0.02 mg/kg,C组静脉注射等容量生理盐水。记录手术结束至出院前PPCs的发生情况,记录手术结束至拔管时间、给药至四个成串刺激比值(TOFr)恢复至0.9的时间、拔管时TOFr、PACU停留时间、拔管后低氧血症(SpO_(2)<90%)的情况并计算拔管时肌松残余(PRNB)发生率,记录首次下床活动时间、术后48 h内镇痛泵总按压次数、有效按压次数、补救镇痛例数、临床肺部感染评分(CPIS)、术后恶心呕吐(PONV)例数、胸管总引流量、胸管留置时间和术后住院时间。结果与C组比较,S组PPCs发生率、拔管时PRNB和拔管后低氧血症发生率明显降低,手术结束至拔管时间、给药至TOFr恢复至0.9的时间、PACU停留时间和术后首次下床活动时间明显缩短,拔管时TOFr明显升高,CPIS评分明显降低(P<0.05);N组手术结束至拔管时间、给药至TOFr恢复至0.9的时间、PACU停留时间明显缩短,拔管时TOFr明显升高,拔管时PRNB发生率明显降低(P<0.05)。与N组比较,S组拔管时PRNB发生率明显降低,手术结束至拔管时间、给药至TOFr恢复至0.9的时间、PACU停留时间和术后首次下床活动时间明显缩短,拔管时TOFr明显升高(P<0.05)。三组其余指标差异均无统计学意义。结论舒更葡糖钠在胸腔镜肺切除术后可快速拮抗残余肌松,降低PPCs和拔管时PRNB发生率,促进患者术后快速康复。

关键词：舒更葡糖钠胸腔镜肺切除术术后肺部并发症术后恢复

Physiological Responses of Different Kinds of Vegetable Seedlings to Polycyclic Aromatic Hydrocarbons Stress

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Agricultural Biotechnology 2019年第5期8卷 37-41,46页

作者： Xuan TANG Minghua LONG Shuangyu QIAO pengxin li Huimin ZHANG Yongsheng liANG Agricultural College Guangxi UniversityNanning 530004China Nanning Vegetable Research Institute Nanning 530000China

This study was conducted to explore the effects of polycyclic aromatic hydrocarbons (PAHs) on the growth and physiological characteristics of vegetable seedlings.Cucumber,Chinese cabbage and radish were cultured under the stress of 16 PAHs at different concentrations of 0.3,0.6 and 0.9 mg/L,respectively,with the seedlings cultured without PAHs as the control,to study the growth and physiological responses of various vegetable seedlings under PAHs stress.The results showed that the leaf width,fresh weight,CAT activity and POD activity of cucumber and the chlorophyll b content and CAT activity of radish reached the minimum values when treated with 0.3 mg/L PAHs.When the treatment concentration was 0.6 mg/L,the POD activity of cucumber,the vitamin C content of Chinese cabbage and the MDA content of radish were the smallest.The dry weight of cucumber,the fresh weight of Chinese cabbage and the fresh weight and POD activity of radish reached the minimums under the treatment of 0.9 mg/L PAHs.Different concentrations of PAHs could promote the synthesis and photosynthesis of chlorophyll in cucumber and Chinese cabbage leaves and the vitamin C content in radish.With the increase of PAHs treatment concentration,the MDA contents of cucumber and Chinese cabbage were on the increase,and reached the maximums under the treatment of 0.9 mg/L PAHs.One of the reasons why different kinds of vegetable seedlings have different physiological responses to PAHs may be related to the differences in the amount of PAHs absorbed by different leaf structures.

关键词： Polycyclic aromatic hydrocarbon Vegetable seedlings Growth Physiology and biochemistry

温度-轨道不平顺组合激励下车-轨-桥耦合动力响应分析

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铁道标准设计 2024年第1期68卷 72-79页

作者：李鹏鑫邢书科王兆刚郭玉鹏杨宇栓杨荣山西南交通大学高速铁路线路工程教育部重点实验室成都610031 中铁上海工程局集团有限公司上海201906 山东省路桥集团有限公司济南250101 山东铁路投资控股集团有限公司济南250101

为研究温度-轨道不平顺组合激励下千米级矮塔斜拉桥上无砟轨道的行车安全,根据运营环境确定温度荷载工况,并采用ANSYS进行静力分析,确定最不利温度荷载工况。基于车-轨-桥耦合动力分析理论,分析温度-轨道不平顺组合激励下千米级的矮塔... 详细信息

为研究温度-轨道不平顺组合激励下千米级矮塔斜拉桥上无砟轨道的行车安全,根据运营环境确定温度荷载工况,并采用ANSYS进行静力分析,确定最不利温度荷载工况。基于车-轨-桥耦合动力分析理论,分析温度-轨道不平顺组合激励下千米级的矮塔斜拉桥上无砟轨道行驶高速列车的动力响应,计算不同行车速度对车辆和桥梁动力响应的影响,并根据现有规范标准,评价千米级的矮塔斜拉桥上无砟轨道的行车安全,提出温度-轨道不平顺组合激励下桥上安全行车的舒适行驶速度范围。分析结果表明:以350km/h设计行车速度过桥时,动车、拖车垂向加速度最大值分别为0.8 m/s^(2)和0.66 m/s^(2),各动力响应数据均处于优良水平,满足相关规范要求;车体的加速度最值与行车速度呈正相关趋势;行车速度为400 km/h时,动车车体垂向加速度最大值为0.95 m/s^(2),是行车速度为250 km/h的1.48倍;当车速达到400 km/h时,Sperling舒适性指标由“优秀”转为“良好”,行车舒适度相对较差。为保证桥上行车安全,建议行车速度不超过400 km/h。

关键词：高速铁路斜拉桥无砟轨道组合不平顺动力响应

Dual sliding mode coordinated control of manipulator grasping system with visual assistance

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Control Theory and Technology 2024年第1期22卷 106-121页

作者： pengxin Zhang Haisheng Yu Xiangxiang Meng Zhe li Qing Yang Xunkai Gao College of Automation Qingdao UniversityQingdao266071ShandongChina Shandong Province Key Laboratory of Industrial Control Technology Qingdao266071ShandongChina

The operation efficiency of the manipulator is placed in the primary position in automatic production. This paper proposes a coordinated control strategy for joint servo and visual servo to enable timely transfer and accurate gripping in the working area. Aiming at the issues of chattering and slow convergence of traditional sliding mode controller, a fast variable power reaching rate on the basis of the non-singular fast terminal sliding mode controller is proposed, which can effectively reduce the convergence time and chattering. For the purpose of addressing the problem that the traditional visual servo control method is sensitive to the environment, a visual servo controller based on integral sliding mode is proposed, to ensure the favorable positioning accuracy of the manipulator. Based on the two proposed controllers mentioned above, a coordinated control strategy is used to implement the control of the manipulator. Finally, the upper computer software is developed using the C# programming language to monitor the workstation. The feasibility of the above-mentioned method is verified through multiple simulations and experiments.

关键词： Automatic production Joint servo Visual servo Coordinated control Non-singular fast terminal sliding mode Integral sliding mode

Electrical discharge and arc milling with automatic tracking of optimal flushing direction:A novel high-efficiency compound machining method

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Chinese Journal of Aeronautics 2024年第3期37卷 351-364页

作者： Xinlei WU Yonghong liU pengxin ZHANG liang QI Dege li Chi MA Renjie JI College of Mechanical and Electronic Engineering China University of Petroleum(East China)Qingdao 266580China School of Mechanical and Power Engineering Nanjing Tech UniversityNanjing 211816China

The arc milling method has the advantages of high machining efficiency and low cost and is independent of the strength and hardness of machined materials.However,frequent electrode back-offs and the risk of workpiece burning may occur if erosion products are not removed promptly.In this study,it was found that the flushing method of the working medium had a significant impact on the machining performance of arc milling.Based on this,a novel highefficiency compound machining method of electrical discharge and arc milling with automatic tracking of the optimal flushing direction was proposed.An automatic tracking optimizer for external working medium injection was designed to determine the optimal external flushing direction according to the feed direction.The influence of flushing methods,working mediums,and machining parameters on the machining efficiency,tool electrode wear rate,machining error,and surface integrity of titanium alloys were investigated.The results indicated that better machining performance and environmental friendliness were achieved using the compound flushing method of outer compressed air and inner deionized water.Additionally,the automatic tracking flushing method in the opposite direction of the feed direction showed superior results compared to other directions.The material removal rate with the opposite direction injection could be increased up to 1.62 times that of the same direction,and the relative electrode wear rate could be reduced by 14.76%.This novel method has broad application prospects for machining parts with difficult-to-cut materials in aerospace and military industries.

关键词： Arc milling Dielectric Difficult-to-cut materials Electric discharge machining Erosion Material removal rate

Dammarane-type triterpenoids from Gynostemma longipes and their protective activities on hypoxia-induced injury in PC12 cells

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Chinese Journal of Natural Medicines 2024年第5期22卷 466-480页

作者： liANG Haizhen CHEN Xiaojuan li Qi ZHANG Mengmeng LU pengxin ZHANG Jie SONG Juan ZHANG Tao GUO Baolin MA Baiping Department of Pharmaceutical Sciences Beijing Institute of Radiation MedicineBeijing 100850China Institute of Medicinal Plant Development Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100193China AnKang Chia Tai Pharmaceutical Co. Ltd.Shaanxi 725000China

Sixteen new dammarane-type triterpenoid saponins(1-16)featuring diverse structural variations in the side chain at C-17,along with twenty-one known analogues(17-37),have been isolated from the rhizomes of Gynostemma longipes C.Y.Wu,a plant renowned for its medicinal and edible properties.The structural elucidation of these compounds was accomplished through comprehensive analyses of 1D and 2D NMR and HRMS spectroscopic data,supplemented by comparison with previously reported data.Subsequent assays on the isolates for their protective effects against hypoxia-induced damage in pheochromocytoma cells(PC12 cells)revealed that nine saponins exhibited significant anti-hypoxic activities.Further investigation into the anti-hypoxia mechanisms of the representative saponins demonstrated that compounds 22 and 36 markedly reduced the levels of hypoxia-induced apoptosis.Additionally,these compounds were found to decrease the release of lactate dehydrogenase(LDH)and malondialdehyde(MDA),while increasing the activity of superoxide dismutase(SOD),thereby indicating that the saponins could mitigate hypoxia-induced injuries by ameliorating apoptosis and oxidative stress.These findings offer substantial evidence for the future utilization and development of G.longipes,identifying dammarane-type triterpenoid saponins as its active anti-hypoxic constituents.

关键词： Gynostemma longipes Dammarane-type saponins Anti-hypoxia effect Apoptosis

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环氧/POSS复合电介质介电与热学性能

电工技术学报 2022年第2期37卷 291-298页

作者：李鹏新崔浩喆邢照亮郭宁闵道敏电力设备电气绝缘国家重点实验室(西安交通大学) 西安710049 先进输电技术国家重点实验室(全球能源互联网研究院有限公司) 北京102209 强脉冲辐射环境模拟与效应国家重点实验室(西北核技术研究院) 西安710024

研究缩水甘油基-笼型聚倍半硅氧烷(G-POSS)对环氧树脂(EP)介电性能与热学性能的影响和作用机理。实验制备G-POSS质量分数在0%、0.5%、1%、2%、3%和5%的环氧/POSS复合电介质试样。测试和研究G-POSS质量分数对环氧/POSS复合电介质相对介... 详细信息

研究缩水甘油基-笼型聚倍半硅氧烷(G-POSS)对环氧树脂(EP)介电性能与热学性能的影响和作用机理。实验制备G-POSS质量分数在0%、0.5%、1%、2%、3%和5%的环氧/POSS复合电介质试样。测试和研究G-POSS质量分数对环氧/POSS复合电介质相对介电常数、交流击穿场强、玻璃化转变温度等的影响。当G-POSS质量分数较低时,环氧/POSS复合电介质性能随G-POSS质量分数增加而不断提高;在G-POSS质量分数达到2%时,复合电介质各项性能均得到较大程度的提升;当继续增加G-POSS质量分数时,环氧/POSS复合电介质的性能开始下降,甚至劣于纯环氧试样。分析认为,G-POSS与环氧基体间形成的大量交联网状结构对环氧/POSS复合电介质性能的影响巨大。

关键词：环氧树脂 POSS 复合材料介电性能

阿帕替尼联合肝动脉化疗栓塞术治疗肝癌的效果分析

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中国社区医师 2023年第32期39卷 70-72页

作者：李鹏鑫邹平市人民医院肿瘤科山东滨州256200

目的:分析阿帕替尼联合肝动脉化疗栓塞术(TACE)治疗肝癌的效果。方法:选取2022年1—12月邹平市人民医院收治的70例肝癌患者作为研究对象,采用随机数字表法分为两组,各35例。对照组接受TACE治疗,观察组在对照组基础上联合阿帕替尼治疗。... 详细信息

目的:分析阿帕替尼联合肝动脉化疗栓塞术(TACE)治疗肝癌的效果。方法:选取2022年1—12月邹平市人民医院收治的70例肝癌患者作为研究对象,采用随机数字表法分为两组,各35例。对照组接受TACE治疗,观察组在对照组基础上联合阿帕替尼治疗。比较两组治疗效果。结果:两组客观缓解率比较,差异无统计学意义(P>0.05);观察组疾病控制率高于对照组,差异有统计学意义(P=0.022)。治疗3个月后,两组血管内皮生长因子(VEGF)、甲胎蛋白(APF)水平低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗6个月后,两组VEGF、APF水平低于治疗前与治疗3个月后,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组胆红素、丙氨酸氨基转移酶水平高于治疗前,但观察组低于对照组,两组白蛋白水平低于治疗前,但观察组高于对照组,差异有统计学意义(P<0.05)。结论:阿帕替尼联合TACE治疗肝癌的效果显著,可提高疾病控制率,降低肿瘤标志物与复发转移指标水平,减小对患者肝功能的影响。

关键词：阿帕替尼肝动脉化疗栓塞术肝癌血管内皮生长因子甲胎蛋白