检索结果-南通市图书馆

Organic Nanocrystals Based on a Solid-emission-tunable AIEgen for Cell Imaging

Chemical Research in Chinese Universities 2021年第1期37卷 129-136页

作者： YANG Liming GUO Lixin YU Hao WANG Guan SUN Jiangman zhang pengfei GU Xinggui TANG Ben Zhong Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Materials Science and EngineeringState Key Laboratory of Chemical Resource EngineeringBeijing University of Chemical TechnologyBeijing100029P.R.China Guangdong Key Laboratory of Nanomedicine Shenzhen Engineering Laboratory of Nanomedicine and NanoformulationsCAS Key Laboratory of Health InformaticsInstitute of Biomedicine and BiotechnologyShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen518055P.R.China Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and ReconstructionInstitute for Advanced StudyThe Hong Kong University of Science and TechnologyHong KongP.R.China

The development of fluorescent nanocrystals based on organic small molecules is of great importance in bioimaging due to the merits of easy modification,high brightness and excellent photostability,however suffering from the emission-detrimental aggregation-caused quenching(ACQ)***,we successfully designed and synthesized an AIE-active di(N,N-dimethylaniline)-dibenzofulvene(named as NFTPE),which exhibits the crystallization-induced emission enhancement(CIEE)***,two types of yellow-and orange-emissive crystals for NFTPE were obtained,exhibiting aggregation microenvironment-dependent emission tuning in the solid ***-crystal analysis and density functional theory(DFT)calculations reveal that different aggregation microenvironments result in the distinct molecular conformation for various ***,the crystallization of NFTPE in an aqueous solution under the assistance of amphiphilic PEG polymer matrices could be monitored in situ by the fluorescence changes,facilitating the preparation of NFTPE nanocrystals(NFTPE-NCs)by adjusting the aggregation *** obtained NFTPE-NCs exhibit the superior performance in cell imaging in respect to high brightness,photostability,and biocompatibility,thus demonstrating the potential in bioimaging applications.

关键词： Aggregation-induced emission(AIE) Crystallization-induced emission enhancement(CIEE) Aggregation microenvironment Nanocrystal Cell imaging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ASTM:Developing the web service for anthrax related spatiotemporal characteristics and meteorology study

引用

Quantitative Biology 2022年第1期10卷 67-78页

作者： Shiwei Fan Ming Xiao Boyu Sun Weizhong Zhou Qingrong Chen Weimin Lv pengfei zhang Le zhang College of Computer Science Sichuan UniversityChengdu 610065China Gannan Center for Disease Control and Prevention Hezuo 747000China Gannan Blood Station Hezuo 747000China Department of Medical Oncology Cancer CenterWest China HospitalSichuan UniversityChengdu 610065China Med-X Center for Informatics Sichuan UniversityChengdu 610065China

Background:Anthrax is a zoonotic infectious disease caused by Bacillus *** the spatiotemporal characteristics of anthrax and the impact of meteorological factors on the incidence of anthrax is helpful for the prevention and control of ***:At first,we applied the Granger causality test to explore the spatiotemporal characteristics of anthrax transmission between the counties and cities of Gannan Tibetan Autonomous Prefecture,Gansu Province of ***,we constructed three generalized linear models to analyze the impact of meteorological factors on the monthly number of anthrax cases in Gannan Tibetan Autonomous ***,we developed an easy-to-use online web server that integrates the above ***:This study developed an online service website(ASTM,http://***/anthrax/***)for the analysis and visualization of anthrax,which not only can investigate the correlation of anthrax among different regions in Gannan Tibetan Autonomous Prefecture,but also can analyze the correlation between meteorological factors and!the number of anthrax ***:Our study not only explored spatiotemporal characteristics of anthrax transmission,but also analyzed the impact of seven meteorological factors on the monthly number of anthrax ***,the online service website which integrates the above functions is useful for the prevention and control of anthrax.

关键词： time series analysis correlation analysis visualization web service data mining

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The bacterial small RNAs: The new biomarkers of oral microbiotaassociated cancers and diseases

引用

BIOCELL 2023年第10期47卷 2187-2193页

作者： MENGYING MAO TING DONG YANJING LIANG KEYONG YUAN QIAOQIAO JIN pengfei zhang ZHENGWEI HUANG Department of Endodontics Shanghai Ninth People’s HospitalCollege of StomatologyShanghai Jiao Tong University School of MedicineShanghaiChina National Clinical Research Center for Oral Diseases ShanghaiChina Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology ShanghaiChina Department of Nursing Shanghai Ninth People’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

The oral microbiota is a vital part of the human microbiota that functions in various physiological processes and ishighly relevant to cancers and other diseases. With the alterations of host immune competence, the homeostatic balanceexisting between the oral microbiota and host may be disturbed and result in the development of diseases. Numerousobservations have suggested that small RNAs are key regulators of bacterial pathogenesis and bacteria-host ***, bacterial small RNAs are considered to be promising biomarkers for the development of novel, and efficacioustherapies for oral dysbiosis. Mechanistic insights into how oral pathogens communicate with other bacteria or host cellsin oral cancers via small RNAs are hot topics of research. Current studies also have begun to elucidate the key role oforal microbiota in the development of systemic diseases. This article discusses existing findings and nascent mechanismsgoverning the small RNA-based interactions between oral microbiota and associated diseases. The knowledge of suchinteractions is key in planning approaches to reverse dysbiosis to achieve health.

关键词： Oral microbiota Biomarkers sRNAs OSCC Oral diseases

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A motion compensation method for wide-swath synthetic aperture sonar

引用

Chinese Journal of Acoustics 2016年第3期35卷 277-291页

作者： zhang pengfei JIANG Zelin LIU Wei LIU jiyuan zhang Chunhua Institute of Acoustics Chinese Academy of Sciences University of Chinese Academy of Sciences

When the swath of Synthetic Aperture Sonar（SAS） is considerably wide, the spacevariant effect of motion errors becomes remarkable. This space-variant effect makes Displace Phase Center Algorithm（DPCA） invalid. To solve the problem, a motion compensation method for wide-swath SAS is proposed. This method uses mixed modulated Lagrange explicit time delay estimation（MMLETDE） to estimate the time delay between two successive pings of the raw echo data, and then motion errors are fitted by linear regression. After that, the raw echo data can be precisely compensated point by point with the estimations of motion *** results show that the proposed method can obtain better motion estimation results than DPCA. The resolution measured on the reconstructed image processed by the proposed method is very close to the theoretical resolution. The lake trail results of high frequency and low frequency SAS data show that the quality of the images of the terrain area and small targets is significantly improved.

关键词： DPCA A motion compensation method for wide-swath synthetic aperture sonar SAS ETDE

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rapid alkenylation of quinoxalin-2(1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis

引用

Chinese Chemical Letters 2021年第11期32卷 3627-3631页

作者： Lin Huang Jun Xu Lei He Chenfeng Liang Yani Ouyang Yongping Yu Wanmei Li pengfei zhang College of Material Chemistry and Chemical EngineeringHangzhou Normal UniversityHangzhou 311121China College of Pharmaceutical Science Zhejiang UniversityHangzhou 310058China

Herein,a rapid alkenylation of quinoxalin-2(1H)-ones enabled by a combination of Mannich-type reaction and solar photocatalysis is demonstrated.A wide range of functional groups are compatible,affording the corresponding products in moderate-to-good *** experiments illustrate that the in situ generated^(1)O_(2)plays a central role in this *** green and efficient strategy provides a practical solution for the synthesis of potentially bioactive compounds that containing a 3,4-dihydroquinoxalin-2(1H)-one structure.

关键词： Alkenylation Quinoxalin-2(^(1)H)-ones Methyl ketones Mannich-type reaction Solar photocatalysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Metastable amorphous chromium-vanadium oxide nanoparticles with superior performance as a new lithium battery cathode

引用

Nano Research 2014年第11期7卷 1604-1612页

作者： Jinzhi Sheng Qidong Li Qiulong Wei pengfei zhang Qinqin Wang Fan Lv Qinyou An Wei Chen Liqiang Mai State Key Laboratory of Advanced Technology for Materials Synthesis and Processing WUT-Harvard Joint Nano Key LaboratoryWuhan University of Technology Wuhan 430070 China

The main drawbacks of vanadium oxide as a cathode material are its low conductivity, low practical capacity and poor cycling stability. Adding Cr can improve its conductivity and a metastable amorphous state may provide higher capacity and stability. In this work, metastable amorphous Cr-V-O nano- particles have been successfully prepared through a facile co-precipitation reaction followed by annealing treatment. As a cathode material for lithium batteries, the metastable amorphous Cr-V-O nanoparticles exhibit high capacity （260 mAh/g at 100 mA/g between 1.5-4 V）, low capacity loss （more than 80% was retained after 200 cycles at 100 mA/g） and high rate capability （up to 3 A/g）.

关键词： Cr2V4O13 nanoparticles metastable amorphous structure lithium battery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Physical-property cutoffs of tight reservoirs by field and laboratory experiments: a case study from Chang 6, 8–9 in Ordos Basin

引用

Frontiers of Earth Science 2021年第2期15卷 471-489页

作者： Bingbing SHI Xiangchun CHANG Zhongquan LIU Ye LIU Tianchen GE pengfei zhang Yongrui WANG Yue WANG Lixin MAO College of Earth Science and Engineering Shandong University of Science and TechnologyQingdao 266590China Laboratory for Marine Mineral Resources Pilot National Laboratory for Marine Science and TechnologyQingdao 266071China Petroleum Exploration and Development Research Institute Shengli Oilfield Company of SINOPECDongying 257015China Jiangsu Design Institute of Geology for Mineral Resources Xuzhou 221006China

Tight sandstone reservoirs are generally characterized by complex reservoir quality,non-Darcy flow,and strong *** utilized for evaluating physical property cutoffs of conventional reservoirs maybe ***,a comprehensive investigation on physical property cutoffs of tight sandstone reservoirs is crucial for the reserve evaluation and successful *** this study,a set of evaluation approaches take advantage of field operations(i.e.,core drilling,oil testing,and wireline well logging data),and simulation experiments(i.e.,high-pressure mercury injection-capillary pressure(MICP)experiment,oil-water relative permeability experiment,nuclear magnetic resonance(NMR)experiment,and biaxial pressure simulation experiment)were comparatively optimized to determine the physical property cutoffs of effective reservoirs in the Upper Triassic Chang 6,Chang 8 and Chang 9 oil layers of the Zhenjing *** results show that the porosity cutoffs of the Chang 6,Chang 8,and Chang 9 oil layers are 7.9%,6.4%,and 8.6%,and the corresponding permeability are 0.08 mD,0.05 mD,and 0.09 mD,*** with wireline well logging,mud logging,and oil testing,the cut-off of the thickness of single-layer effective reservoirs are approximately 3.0 m,3.0 m,and 2.0 m,*** on the cutoffs of critical properties,a superimposed map showing the planar distribution of the prospective targets can be mapped,which may delineate the effective boundary of prospective targets for petroleum exploration of tight sandstone reservoirs.

关键词： tight sandstone reservoirs cutoffs of petrophysical property field operations simulation experiments Yanchang Formation Ordos Basin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Visible-light-induced C–H sulfenylation of quinoxalin-2(1H)-ones with disulfides by sustainable cerium catalysis

引用

Green Synthesis and Catalysis 2023年第3期4卷 226-230页

作者： Lixi zhang Jingwen He pengfei zhang Dancheng Zhu Kai Zheng Chao Shen Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province College of Biology and Environmental EngineeringZhejiang Shuren UniversityHangzhou 310015China College of Environment Zhejiang University of TechnologyHangzhouZhejiang 310032China College of Material Chemistry and Chemical EngineeringKey Laboratory of Organosilicon Chemistry and Material TechnologyMinistry of EducationHangzhou Normal UniversityHangzhou 311121China

Using visible light as energy to form free radicals has important synthetic value.A novel and efficient visible-lightmediated strategy has been developed for the generation of thiobenzene radicals through cerium-catalyzed activation of the *** this photochemical reaction,various 3-sulfenylated quinoxalin-2(1H)-ones can be conveniently obtained in good yields with good functional group *** transformation provides an alternative that allows rapid access to various C3 sulfenylated quinoxalin-2(1H)-ones in a sustainable and practical manner.

关键词： Quinoxalin-2(1H)-ones Disulfides Sulfenylation Visible light Cerium catalysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transcriptome-wide Dynamics of m^(6)A mRNA Methylation During Porcine Spermatogenesis

引用

Genomics, Proteomics & Bioinformatics 2023年第4期21卷 729-741页

作者： Zidong Liu Xiaoxu Chen pengfei zhang Fuyuan Li Lingkai zhang Xueliang Li Tao Huang Yi Zheng Taiyong Yu Tao zhang Wenxian Zeng Hongzhao Lu Yinghua Lv Key Laboratory for Animal Genetics Breeding and Reproduction of Shaanxi ProvinceCollege of Animal Science and TechnologyNorthwest A&F UniversityYangling 712100China School of Biological Science and Engineering Shaanxi University of TechnologyHanzhong 723001China College of Chemistry and Pharmacy Northwest A&F UniversityYangling 712100China

Spermatogenesis is a continual process that occurs in the testes,in which diploid spermatogonial stem cells(SSCs)differentiate and generate haploid *** highly efficient and intricate process is orchestrated at multiple levels.N^(6)-methyladenosine(m^(6)A),an epigenetic modification prevalent in mRNAs,is implicated in the transcriptional regulation during ***,the dynamics of m^(6)A modification in non-rodent mammalian species remains ***,we systematically investigated the profile and role of m^(6)A during spermatogenesis in *** analyzing the transcriptomic distribution of m^(6)A in spermatogonia,spermatocytes,and round spermatids,we identified a globally conserved m^(6)A pattern between porcine and murine genes with spermatogenic *** found that m^(6)A was enriched in a group of genes that specifically encode the metabolic enzymes and *** addition,transcriptomes in porcine male germ cells could be subjected to the m^(6)A *** data show that m^(6)A plays the regulatory roles during spermatogenesis in pigs,which is similar to that in *** of this point are three genes(SETDB1,FOXO1,and FOXO3)that are crucial to the determination of the fate of *** the best of our knowledge,this study for the first time uncovers the expression profile and role of m^(6)A during spermatogenesis in large animals and provides insights into the intricate transcriptional regulation underlying the lifelong male fertility in non-rodent mammalian species.

关键词： N^(6)-methyladenosine Spermatogonial stem cell Spermatogenesis SETDB1 Pig

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Desorption Behavior of Coalbed Gas and its Anisotropy Within High Rank Coal Reservoir in the Zhengzhuang Block of the Southern Qinshui Basin,China

引用

Acta Geologica Sinica(English Edition) 2015年第A01期89卷 55-58页

作者： LI Junqian LU Shuangfang zhang pengfei zhang Ping CHEN Jianjun Unconventional Oil & Gas and Renewable Energy Research Institute China University of PetroleumQingdao

1 Introduction With the exploration and development of coalbed methane （CBM）, there has been a growing interest in the coalbed gas desorption behavior and its geological controls. To date, two primary species including the desorption rate and desorption velocity of the coalbed gas have been studied widely （e.g. Pollard and Aydin, 1998; Chen et al., 2008; Liu et al., 2012）.

关键词： COALBED methane RESERVOIRS COAL GASES -- Absorption & adsorption ANISOTROPY

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：