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Detection of Ultra Trace Amount Gossypol with Chemiluminescence Using Capillary Electrophoresis as Injection Techniques

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Chinese Chemical Letters 2005年第12期16卷 1649-1651页

作者： Er Bao LIU Min ZHANG Bing Chun XUE peng xiang zhao Yin LIU School of Chemistry and Life Sciences Tianjin Normal University Tianjin 300074

Detection of ultra trace amount gossypol is reported. It is based on luminolhexacyanoferrate（Ⅲ） chemiluminescence reaction with gossypol as a sensitizer. The detection limit （3 σ ）of gossypol reaches 5.21 × 10^... 详细信息

关键词： Capillary electrophoresis chemiluminescence gossypol

A Pitch-variation Moiré Fringes Method of Temporal Phase Unwrapping Profilometry

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Optoelectronics Letters 2007年第3期3卷 215-218页

作者： Tian Jin-dong peng xiang zhao Xiao-bo Key laboratory of Optoelectronic Devices and Systems of Education Ministry Institute of Optoelectronics ShenzhenUniversity Shenzhen 518060 China

A method of pitch-variation moiré fringes is proposed to realize the temporal phase unwrapping for three-dimensional profilometry. On the basis of the principle of moiré pattern,we achieve variable spatial frequencies of fringes in a moiré pattern by rotating two gratings. Furthermore a five-point fitting method is used to automatically compute the central position of side-lobe spectrum of the moiré fringes. Finally,a generalized temporal phase unwrapping algorithm is intro-duced to process the three-dimensional reconstruction. The theoretical analysis and experimental results show the validity of the proposed method.

关键词：表面光洁度测量法节距变分莫尔条纹法位相展开

Effect of Mg addition on temper embrittlement in 2.25Cr–1Mo steel doped with 0.056% P–Mg segregation behavior at grain boundary

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Journal of Iron and Steel Research International 2021年第10期28卷 1259-1267页

作者： Xiao-bing Li Xin Dong peng-xiang zhao Wei-wei Xing Lei-lei Ding Nan-nan Zhang Ying-che Ma Kui Liu Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of ScienceShenyang110016LiaoningChina CAS Key Laboratory of Nuclear Materials and Safety Assessment Shenyang110014LiaoningChina School of Materials Science and Engineering Shenyang University of TechnologyShenyang110870LiaoningChina School of Materials Science and Engineering University of Science and Technology of ChinaHefei230026AnhuiChina

To verify the microalloying function and segregation behavior of trace Mg at grain boundary in steel,the 2.25Cr–1Mo steel doped with 0.056%P containing different Mg contents was refined with a vacuum-induction *** effects of trace Mg addition on the temper embrittlement susceptibility of 2.25Cr–1Mo steel were studied by step-cooling test and the segregation behavior of Mg at grain boundary was explored by Auger electron *** is shown that P-induced temper embrittlement susceptibility can be reduced after subjecting to step-cooling treatment with trace Mg addition,mainly benefited from the segregation of Mg at grain *** segregation can decrease the segregation amounts of P and S,especially for P,and increase the grain boundary cohesion,reducing the adverse effect on temper embrittlement caused by P and S.

关键词： 2.25Cr-1Mo steel Temper embrittlement Mg P Segregation Auger electron spectroscopy

Association of the macrophage migration inhibitory factor promoter polymorphisms with benign lymphoepithelial lesion of lacrimal gland

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International Journal of Ophthalmology(English edition) 2017年第8期10卷 1229-1232页

作者： Qin-Jian Li peng-xiang zhao Xu-Juan Zhang Yang Yi Dan-Ying Cheng Jian-Min Ma Xue-Mei Ma College of Life Science and Bio-engineering Beijing Universityof Technology Beijing 100124 China Institute of Infectious Diseases Beijing Ditan HospitalCapital Medical University Beijing 100015 China Beijing Tongren Eye Center Beijing Tongren HospitalCapital Medical University Beijing Ophthalmology &VisionScience Key Lab Beijing 100730 China

AIM： To identify the association of the macrophage migration inhibitory factor （MIF） gene polymorphism with the susceptibility of benign lymphoepithelial lesions （BLEL） of the lacrimal gland. METHODS： A total of 40 BLEL of lacrimal gland cases were matched with 40 healthy subjects （HS）. Extraction the plasma and whole blood DNA of patients of lacrimal gland BLEL and HS. Elisa and polymerase chain reaction was used to determine in plasma contents of MIF and MIF gene SNP-173G〉C and STR -794 CATT（8） polymorphism, respectively. RESULTS： The MIF levels in plasma were significantly higher in patients with lacrimal gland *** versus HS （P〈0.001）. The -173 G〉C MIF polymorphism was significantly associated with lacrimal gland BLEL, with a significantly higher frequency of the C allele in lacrimal gland BLEL patients compared with HS （OR=2.38, 95% C1=1.07-5.31, P=0.032）, and the -173 C/x is more frequent in patients than in HS, P=0.037. Besides, we found that the carriage rate of the MIF -173C/x is associated with higher plasma levels of MIF in the BLEI. of lacrimal gland. CONCLUSION： MIF -173G/C variants play an insidious role in susceptibility of BLEL of lacrimal gland. Otherwise,there is no statistically significant correlation exists between MIF-794 CATT （） and BLEL of lacrimal gland.

关键词： benign lymphoepithelial lesion lacrimal gland macrophage migration inhibitory factor gene polymorphism

Association analysis of BclI with benign lymphoepithelial lesions of the lacrimal gland and glucocorticoids resistance

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International Journal of Ophthalmology(English edition) 2023年第11期16卷 1734-1745页

作者： Xu-Juan Zhang peng-xiang zhao Ming-Shen Ma Hao Wu Rui Liu Hui Wang Meng-Yu Liu Fei Xie Xue-Mei Ma Faculty of Environment and Life Beijing University of TechnologyBeijing 100124China Beijing International Science and Technology Cooperation Base of Antivirus Drug Beijing 100124China Beijing Tongren Hospital Capital Medical UniversityBeijing 100730China State Key Laboratory of Military Stomatology&National Clinical Research Center for Oral Diseases&Shaanxi International Joint Research Center for Oral Diseases Department of General Dentistry and EmergencySchool of StomatologyAir Force MedicalXi’an 710032Shaanxi ProvinceChina

AIM:To evaluate the relationship between gene polymorphism(BclI,ER22/23EK,N363S)and the occurrence,progression and sensitivity to glucocorticoid of lacrimal gland benign lymphoepithelial lesion(LGBLEL).METHODS:Clinical peripheral blood samples of 52 LGBLEL patients and 10 normal volunteers were collected for DNA extraction and polymerase chain reaction sequencing to analyze single nucleotide polymorphism(SNP)*** lacrimal tissues of LGBLEL were surgically removed and made into paraffin sections for subsequent hematoxylin-eosin(HE)and Masson staining *** duration of disease and hormone use of LGBLEL patients from diagnosis to surgery were also *** Meta-analysis follows PRISMA guidelines to conducted a systematic review of human studies investigating the relationship between the NR3C1 BclI polymorphism and glucocorticoids(GCs)***:There was no association between ER22/23EK or N363S and the occurrence of LGBLEL or GCs sensitivity(P>0.05);BclI GC genotype was closely related to GCs resistance(P=0.03)as is the minor allele C(P=0.0017).The HE staining and Masson staining showed that the GC genotype of BclI remarkably slowed down the disease progression and reduced fibrosis(P<0.05),especially for GCs-dependent patients(P<0.0001).Meta-analysis showed that BclI was not significantly associated with GCs ***:The LGBLEL patients who carry the NR3C1 BclI allele C may be more sensitive to GCs and associated with lower fibrosis and slower disease *** results may guide the clinical treatment strategy for the LGBLEL patients.

关键词： lacrimal gland benign lymphoepithelial lesion Bcll single nucleotide polymorphisms glucocorticoids resistance fibrosis

IgG4 and IgE co-positive group found in idiopathic orbital inflammatory disease

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International Journal of Ophthalmology(English edition) 2018年第1期11卷 36-42页

作者： peng-xiang zhao Yao Mawulikplimi Adzavon Jian-Min Ma Lei Shang Dan-Ying Chen Fei Xie Meng-Yu Liu Xin Zhang Bao-Bei Lyu Ming-Zi Zhang Lin-Qi Yang Xue-Mei Ma College of Life Science and Bio-engineering Beijing University of Technology Beijing Ophthalmology & Vision Science Key Lab Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Institute of Infectious Diseases Beijing Ditan Hospital Capital Medical University Department of Plastic Surgery Peking Union Medical College Hospital

AIM： To reveal the cytokines involved in idiopathic orbital inflammatory disease（IOID） and the relationship between Th17 cells, IgE and IOID ***： Whole blood samples were processed immediately after collection and serological IgG4, IgG, and IgE antibodies were tested using ELISA. IOID and orbital cavernous hemangioma（CH） tissue samples underwent Bio-Plex multiplex cytokine detection. Hematoxylin-Eosin（HE） staining of all paraffin samples suggested the histological features of IOIDs, and expressions of IgG4 and IL-17 A in affected tissues were detected by immunohistochemistry. RESULTS： Among 40 IOID plasma samples, 52.5%（21/40） were positive for IgG4 and 25%（10/40） were positive for IgE. Overlapped IgG4 or IgE positive samples accounted for 22.5%（9/40）. Therefore, IOID samples were separated into three groups. The IgE＋/IgG4＋ group had a relevantly lower level of pro-inflammatory cytokine expression. IL-4（Th2 cell related）, IL-10 and TGF-β1（Treg cell immunity related） were elevated in all three groups. Some of the Th17 cell related cytokines（i.e. IL-17 A/F, IL-25, IL-23, and IL-33） displayed higher expression levels in the IgE-/IgG4-group compared to the other two ***： We discovered an IgG4-IgE co-positive group as well as Th17 cell immune involvement in IgG4-IgE co-negative subgtroup in IOID for the first time. The pathogenesis of IOID could differ from different subgroups according to the IgG4 and IgE detection. Therefore, we recommend that, Treatment stratagy should be made according to the clinical assessment of IgG4-IgE and Th17 profile detection.

关键词： idiopathic orbital inflammatory disease IgE IgG4 Th17

Effect of hydrogen intervention on refractory wounds after radiotherapy:A case report

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World Journal of Clinical Cases 2022年第21期10卷 7545-7552页

作者： peng-xiang zhao Rui-Liu Luo Zheng Dang You-Bin Wang Xu-Juan Zhang Zi-Yi Liu Xiao-Hu Wen Meng-Yu Liu Ming-Zi Zhang Yao Mawulikplimi Adzavon Xue-Mei Ma Faculty of Environment and Life Science Beijing International Science and TechnologyCooperation Base of Antivirus DrugBeijing University of TechnologyBeijing 100124China Department of Plastic Surgery Peking Union Medical College HospitalBeijing 100032China

BACKGROUND Patients with keloids who receive radiotherapy(RT)after surgery can develop refractory wounds that cannot be healed by the patient's own repair *** chronic wounds are uneven and complex due to persistent abscess and *** external intervention,they can easily result in local tissue necrosis or,in severe cases,large area tissue resection,amputation,and even *** SUMMARY This article describes the use of hydrogen to treat a 42-year-old female patient with a chronic wound on her left *** patient had a skin graft that involved implanting a dilator under the skin of her left shoulder,and then transferring excess skin from her shoulder onto scar tissue on her *** skin grafting was followed by two rounds of RT,after which the shoulder wound had difficulty *** six months,the patient was treated with 2 h of hydrogen inhalation(HI)therapy per day,in addition to application of sterile gauze on the wound and periodic *** also performed one deep,large,sharp debridement to enlarge the wound *** wound healed completely within 6 mo of beginning the HI *** After HI therapy,the patient showed superior progress in reepithelialization and wound repair,with eventual wound closure in 6 mo,in comparison with the previous failures of hyperbaric oxygen and recombinant bovine basic fibroblast growth factor *** work showed that HI therapy could be a new strategy for wound healing that is cleaner,more convenient,and less expensive than other therapies,as well as easily accessible for further application in clinical wound care.

关键词： Hydrogen Inhalation therapy Wound healing Reepithelialization Refractory wounds Case report

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao xiang Feng Gao Yu-Gui peng peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

基于Sugeno模糊积分的目标识别效果评估

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系统仿真学报 2005年第5期17卷 1175-1178,1199页

作者：李彦鹏黎湘庄钊文国防科技大学电子科学与工程学院空间电子信息技术研究所长沙410073

针对目标识别效果评估,提出一种通用化的评估思路,选取了评估指标及测度方法,并给出识别过程的参照信息以及计算方法。随后,构筑了基于模糊积分的目标识别效果评估模型。最后,结合实测数据和拟合数据完成了仿真。

关键词：目标识别效果评估模糊积分算法