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Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-hui zhang Zhi-Lai Zhan Guang-Lu Chang Yan Gao Xia Li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

新柏氏电脑辅助阅片系统TIS在检测子宫颈/阴道鳞状上皮病变中的应用研究

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现代医学 2016年第9期44卷 1274-1277页

作者：彭辉赵敏张志发郑广娟广东省中医院病理科广东广州510120

目的：比较新柏氏电脑辅助系统（TIS）阅片与单纯人工阅片两种方法在宫颈癌细胞学筛查中的效率、灵敏度和准确性。方法：分别统计单纯人工阅片组和TIS辅助阅片组的每例用时、阳性检出率、活检诊断相符率。结果：总计收集42 430例液基薄... 详细信息

目的：比较新柏氏电脑辅助系统（TIS）阅片与单纯人工阅片两种方法在宫颈癌细胞学筛查中的效率、灵敏度和准确性。方法：分别统计单纯人工阅片组和TIS辅助阅片组的每例用时、阳性检出率、活检诊断相符率。结果：总计收集42 430例液基薄层细胞学检测病例,其中单纯人工阅片25 808例,TIS辅助阅片16 622例,数据显示TIS：（1）平均58.9 s·片-1（每小时约60张玻片）,较单纯人工阅片效率提高40%~250%;（2）ASCUS及以上的总阳性检出率、ASCUS、ASC-H和HSIL检出率分别为8.02%、5.43%、0.17%、0.63%,均高于单纯人工阅片,各组差异有统计学意义（P〈0.05）;（3）经活检证实,TIS与人工阅片相比各组诊断相符率差异无统计学意义。结论：TIS明显缩短了医生阅片的筛查时间;在检测宫颈鳞状上皮病变时TIS优于人工阅片,其敏感度提高不以损失特异度来实现。

关键词：电脑辅助阅片宫颈细胞学宫颈癌筛查

EXPERIMENTAL SIMULATION ON CONTROL ROLLING PROCESS OF 6201 ALUMINUM ALLOY

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中国有色金属学会会刊：英文版 1999年第2期9卷 114-117页

作者： Liu, Yuying hui, zhang peng, Dashu Wang, Caikun Central South Univ of Technology Changsha China

１ＩＮＴＲＯＤＵＣＴＩＯＮ６２０１Ａｌｕｍｉｎｕｍａｌｏｙｉｓｕｓｅｄｆｏｒｏｖｅｒｈｅａｄｃｏｎｄｕｃｔｉｖｅｗｉｒｅ，ｗｈｉｃｈｃａｎｂｅｆａｂｒｉｃａｔｅｄｂｙｔｈｅｆｏｌｏｗｉｎｇｍｅｔｈｏｄｓ［１－４］．（... 详细信息

１ＩＮＴＲＯＤＵＣＴＩＯＮ６２０１Ａｌｕｍｉｎｕｍａｌｏｙｉｓｕｓｅｄｆｏｒｏｖｅｒｈｅａｄｃｏｎｄｕｃｔｉｖｅｗｉｒｅ，ｗｈｉｃｈｃａｎｂｅｆａｂｒｉｃａｔｅｄｂｙｔｈｅｆｏｌｏｗｉｎｇｍｅｔｈｏｄｓ［１－４］．（１）Ｃｏｎｖｅｎｔｉｏｎａｌｐｒｏ...

关键词： aluminum alloycontrol rolling processthermal simulationMg2Si precipitation

hOPE:improved order preserving encryption with the power to homomorphic operations of ciphertexts

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Science China(Information Sciences) 2017年第6期60卷 116-132页

作者： Yanguo peng hui LI Jiangtao CUI Junwei zhang Jianfeng MA Changgen peng School of Computer Science and Technology Xidian University School of Cyber Engineering Xidian University College of Science Guizhou University

Database applications that manage and utilize massive data must address the issues of element comparisons, the core operations in index accessing, metric computations and metric comparisons, and the core operations in result ranking. In the cloud era, to avoid private information leakage, encrypted data are subcontracted, and resolutions for the problems that arise in three operations over ciphertexts are urgently required. Indeed, it is possible to handle element comparison through order preserving encryption/encoding(OPE) or metric computation through homomorphic encryption(HE) directly over ciphertexts. Unfortunately,the simultaneous achievement of both goals(i.e., metric computation and comparison) by directly combining OPE and HE remains intractable. In this work, an improved OPE, named h OPE, is proposed to support homomorphic operations over ciphertexts in addition to comparisons. Based on h OPE, Ah OPE and Ph OPE are designed to support homomorphic addition and product, respectively. Both schemes are proved to be indistinguishable under operated and ordered chosen-plaintext attack(IND-O2CPA) secure when the adopted HE algorithm provides indistinguishable under ordered chosen-plaintext attack(IND-OCPA secure). h OPE is a general construction that supports arbitrary HE algorithms and achieves consistent security. We deploy Ah OPE and Ph OPE in practice with a trusted/untrusted third party and compare the result with the state-of-the-art methods. The results show that our presented algorithms need few interactions and fill the gap between OPE and HE.

关键词： order preserving encoding homomorphic operation B+-tree lookup table provable secure

Ammonia removal from low-strength municipal wastewater by powdered resin combined with simultaneous recovery as struvite

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Frontiers of Environmental Science & Engineering 2021年第1期15卷 125-134页

作者： Kuo Fang Fei peng hui Gong Huanzhen zhang Kaijun Wang State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China School of Water Resources&Environment China University of GeosciencesBeijing 100083China

Low-strength municipal wastewater is considered to be a recoverable nutrient resource with economic and environmental ***,various technologies for nutrient removal and recovery have been *** this paper,powdered ion exchange resin was employed for ammonia removal and recovery from imitated low-strength municipal *** effects of various working conditions(powdered resin dosage,initial concentration,and pH value)were studied in batch experiments to investigate the feasibility of the approach and to achieve performance *** maximum adsorption capacity determined by the Langmuir model was 44.39 mg/g,which is comparable to traditional ion exchange ***,the effects of co-existing cations(Ca^(2+),Mg^(2+),K^(+))were *** on the above experiments,recovery of ammonia as struvite was successfully achieved by a proposed two-stage crystallization process coupled with a powdered resin ion exchange *** electron microscopy(SEM)and X-ray diffractometry(XRD)results revealed that struvite crystals were successfully gained in alkaline conditions(pH=10).This research demonstrates that a powdered resin and two-stage crystallization process provide an innovative and promising means for highly efficient and easy recovery from low-strength municipal wastewater.

关键词： Ammonia removal and recovery Powdered resin Crystallization process Struvite Co-existing cations

Electrolytic groundwater circulation well for trichloroethylene degradation in a simulated aquifer

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Science China(Technological Sciences) 2021年第2期64卷 251-260页

作者： YUAN SongHu LIU Yang zhang peng TONG Man LIU hui State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesWuhan 430074China

An in situ groundwater remediation process, termed EGCW, was developed in this study by integrating in-well groundwater electrolysis into groundwater circulation well. Groundwater circulation carries electrolytically generated O2 and H2 into the impacted aquifer for in situ biodegradation of contaminants. In a two-dimensional tank filled with field sandy sediments,simulated trichloroethylene(TCE)-contaminated groundwater was circulated between an injection well with electrodes inside and a pumping well. Results from a 50-day EGCW experiment show that in-well electrolysis oxygenated most region near the injection well, and 10 mg/L TCE was mainly biodegraded aerobically to about 2.7 mg/L(73% removal) by the indigenous microbes. Aerobic TCE degradation was enhanced by the pulsed addition of acetate. Together with the proofs of stable carbon isotope fractionation(enrichment factor:-0.57‰–-1.53‰) and microbial community variation after EGCW treatment, aerobic cometabolism was proposed to be the most likely mechanism for TCE degradation. It is interesting to find that the intrinsic organic carbon in aquifer matrix could fuel the aerobic TCE degradation, particularly at low TCE concentrations. EGCW treatment is advantageous in terms of supplying appropriate dosages of electron acceptor(O_(2)) and donor(H_(2)) for in situ bioremediation because groundwater electrolysis and circulation are expedient and controllable.

关键词： electrolytic remediation groundwater circulation wells chlorinated solvents biodegradation

Model for RuhrstahI-Heraeus （RH） decarburization process

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Journal of Iron and Steel Research International 2018年第4期25卷 409-416页

作者： Dong-ping Zhan Yang-peng zhang Zhou-hua Jiang hui-shu zhang School of Metallurgy Northeastern University Shenyang 110819 Liaoning China Shenyang Northeastern Institute of Metal Materials Co. Ltd. Shenyang 110108 Liaoning China School of Materials Science and Engineering Northeastern University Shenyang 110819 Liaoning China Metallurgical Engineering College Liaoning Institute of Science and Technology Benxi 117004 Liaoning China

A mathematical model was established to predict the carbon content of ultralow carbon steel in the Ruhrstahl-Heraeus （RH） process. The model was solved using the fourth-order Runge-Kutta method and assumed that the volume of steel partaking in the reaction depends on the decarburization mechanism. After analyzing the decarburization process using the proposed model, the following conclusions were drawn. First, the initial carbon and oxygen contents in the RH degasser should be stabilized in the range of （200-350） × 10^-6 and （500-700） × 10^-6, respectively. Second, in the initial stage, the pressure should be reduced as quickly as possible. Third, oxygen blowing should begin as early as possible when the forced decarburization is needed and the minimum oxygen flow rate should be 0.1923 m3/（t rain）. Finally, expanding the diameter of the snorkel tube from 480 to 600 mm clearly enhances the decarburization rate.

关键词： RH Model Carbon content Fourth-order Runge-Kutta Ultralow carbon steel Decarburization

100例平板试验阳性患者造影结果分析及其临床意义

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实用医技杂志 2006年第16期13卷 2824-2825页

作者：姚春霞王鹏张卉陈珺宝鸡市中心医院陕西宝鸡721008

目的为了进一步明确诊断冠心病及冠状动脉病变的部位及程度,对冠心病及可疑冠心病患者分别进行运动试验和冠状动脉造影(CAG),以评估二者之间的相关性。方法选择运动试验阳性患者100例与CAG情况进行分析比较以便提高临床诊断符合率。结... 详细信息

目的为了进一步明确诊断冠心病及冠状动脉病变的部位及程度,对冠心病及可疑冠心病患者分别进行运动试验和冠状动脉造影(CAG),以评估二者之间的相关性。方法选择运动试验阳性患者100例与CAG情况进行分析比较以便提高临床诊断符合率。结果有典型的心绞痛,平板试验(TET)阳性与CAG阳性符合率较高;不典型的心绞痛和冠心病危险因素,活动TET与CAG阳性符合率较低。运动试验阳性中,ST段呈水平型或下斜型压低,CAG阳性率高;冠状动脉分支病变,运动试验中出现ST段压低持续时间长,导联数多,两者均多于冠状动脉单支病变。合并高血压或糖尿病患者,运动试验中出现ST段下移的时间早,持续的时间长,与单纯性冠状动脉病变差异有显著的意义。结论TET阳性患者与冠状动脉病变的关系密切。对冠心病的诊断有较高的敏感性和特异性。

关键词： TET CAG 冠心病

Production of light nuclei and hypernuclei at High Intensity Accelerator Facility energy region

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Nuclear Science and Techniques 2017年第4期28卷 84-90页

作者： peng Liu Jin-hui Chen Yu-Gang Ma Song zhang Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201800 China University of Chinese Academy of Sciences Beijing 100049 China

Heavy-ion collisions are powerful tools for studying hypernuclear *** develop a dynamical coalescence model coupled with an ART model(version1.0) to study the production rates of light nuclear clusters and hypernuclei in heavy-ion reactions,for instance,the deuteron(d),triton(t),helium(~3He),and hypertriton(_A^3H)in minimum bias(0-80%centrality)~6Li+^(12)C reactions at beam energy of 3.5A *** penalty factor for light clusters is extracted from the yields,and the distributions of 0 angle of particles,which provide direct suggesetions about the location of particle detectors in the near future facility-High Intensity heavy-ion Accelerator Facility(HIAF) are *** calculation demonstrates that HIAF is suitable for studying hypernuclear physics.

关键词： Heavy-ion accelerator facility Hyperon Hypernuclei Coalescence Light nuclei