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Experimental and numerical study on hysteretic performance of SMA spring-friction bearings

Earthquake Engineering and Engineering Vibration 2016年第4期15卷 597-609页

作者： zhuang peng Xue Suduo Nie Pan Wang Wenting School of Civil and Transportation Engineering Beijing University of Civil Engineering and Architecture Beijing Higher Institution Engineering Research Center of Structural Engineering and New Materials Beijing University of Civil Engineering and Architecture College of Architecture and Civil Engineering Beijing University of Technology

This paper presents an experimental and numerical study to investigate the hysteretic performance of a new type of isolator consisting of shape memory alloy springs and friction bearing called an SMA spring-friction bearing （SFB）. The SFB is a sliding-type isolator with SMA devices used for the seismic protection of engineering structures. The principle of operation of the isolation bearing is introduced. In order to explore the possibility of applying SMA elements in passive seismic control devices, large diameter superelastic tension/compression NiTi SMA helical springs used in the SFB isolator were developed. Mechanical experiments of the SMA helical spring were carried out to understand its superelastic characteristics. After that, a series of quasi-static tests on a single SFB isolator prototype were conducted to measure its force-displacement relationships for different loading conditions and study the corresponding variation law of its mechanical performance. The experimental results demonstrate that the SFB exhibits full hysteretic curves, excellent energy dissipation capacity, and moderate recentering ability. Finally, a theoretical model capable of emulating the hysteretic behavior of the SMA-based isolator was then established and implemented in MATLAB software. The comparison of the numerical results with the experimental results shows the efficacy of the proposed model for simulating the response of the SFB.

关键词： sliding isolation bearing SMA helical spring hysteretic performance quasi-static test theoretical model

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骨关节炎的氧化应激相关基因和免疫浸润分析

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中国组织工程研究 2025年第2期29卷 302-311页

作者：吴傲于鹏滕加文孔鹏卞泗善山东中医药大学第一临床医学院山东省济南市250000 山东中医药大学附属医院山东省济南市250000

背景:目前对于骨关节炎的发病机制尚不清楚,缺乏有效控制疾病的手段,且研究多集中在免疫领域,对氧化应激领域研究较少。目的:探索氧化应激与免疫浸润在骨关节炎中的作用,并预测相关miRNA和治疗药物。方法:从GEO数据库中获取GSE55235数据... 详细信息

背景:目前对于骨关节炎的发病机制尚不清楚,缺乏有效控制疾病的手段,且研究多集中在免疫领域,对氧化应激领域研究较少。目的:探索氧化应激与免疫浸润在骨关节炎中的作用,并预测相关miRNA和治疗药物。方法:从GEO数据库中获取GSE55235数据集(10例骨关节炎样本和10例健康对照样本)和GSE55457数据集(10例骨关节炎样本和10例健康对照样本)进行合并,获取差异表达基因,并结合氧化应激基因得到差异表达氧化应激基因。对差异表达氧化应激基因进行KEGG、GO富集分析,并使用GSEA富集分析评价骨关节炎通路和生物过程。使用STRING在线平台和Cytoscape软件建立了蛋白质相互作用网络,运行Degree算法得到关键基因,从GEO数据库中获取GSE1919作为验证数据集,对关键基因进行差异分析及受试者工作特征曲线分析,得到核心基因。此外,用CIBERSORT对免疫浸润进行评估,并探索核心基因与免疫细胞的相关性,使用TargetScan对核心基因进行miRNA预测及使用DSigDB数据库对靶点药物进行预测。结果与结论:①确定了65个差异表达氧化应激基因和5个核心基因(IL1B、CXCL8、MYC、NFKBIA、JUN);②富集分析结果显示,差异表达氧化应激基因的主要聚焦点包括氧化应激、白细胞介素17、破骨细胞分化、流体剪切应力以及动脉粥样硬化等通路;③5个核心基因的受试者工作特征曲线下面积均>0.85,说明对诊断骨关节具有良好的特异性和敏感性,且与免疫细胞密切关联;④miRNA的预测结果是hsa-miR-3937,治疗小分子药物包括二甲双胍、离子霉素和塞来昔布等。结果表明:骨关节炎中存在氧化应激与免疫浸润,且免疫浸润参与激活氧化应激。核心基因及预测的miRNA可作为诊断骨关节炎的新型标志物,预测的小分子药物可治疗骨关节炎。

关键词：骨关节炎氧化应激免疫浸润差异基因生物标志物 miRNA 药物预测

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Photocatalytic hydrogenation of nitroarenes using Cu1.94S-Zn0.23Cd0.77S heteronanorods

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Nano Research 2018年第7期11卷 3730-3738页

作者： Zhanjun yu Zheng Chen yueguang Chen Qing peng Rui Lin yu Wang Rongan Shen Xing Cao Zhongbin zhuang Yadong Li Department of Chemistry Tsinghua University Beijing 100084 China Faculty of Science Beijing University of Chemical Technology Beijing 100029 China Beijing Advanced Innovation Center for Soft Matter Science and Technology Beijing University of Chemical Technology Beijing 100029 China

Catalytic hydrogenation is an important process in the chemical industry. Traditional catalysts require the effective cleavage of hydrogen molecules on the metal-catalyst surface, which is difficult to achieve with non-noble metal catalysts. In this work, we report a new hydrogenation method based on water/ proton reduction, which is completely different from the catalytic cleavage of hydrogen molecules. Active hydrogen species and photo-generated electrons can be directly applied to the hydrogenation process with Cu1.94S-Zn0.23Cd0.775 semiconductor heterojunction nanorods. Nitrobenzene, with a variety of substituent groups, can be efficiently reduced to the corresponding aniline without the addition of hydrogen gas. This is a novel and direct pathway for hydrogenation using non-noble metal catalysts.

关键词： photocatalytic hydrogenation nitroarene selectivity heteronanorods

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Immigrant Pantoea agglomerans embedded within indigenous microbial aggregates: A novel spatial distribution of epiphytic bacteria

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Journal of Environmental Sciences 2014年第2期26卷 398-403页

作者： Qing yu Anzhou Ma Mengmeng Cui Xuliang zhuang Guoqiang zhuang Research Center for Eco-Environmental Sciences Chinese Academy of Sciences

Immigrant bacteria located on leaf surfaces are important to the health of plants as well as to people who consume fresh fruits and vegetables. However, the spatial distribution and organization of these immigrant bacteria on leaf surfaces are still poorly understood. To examine the spatial organization of these strains, two bacterial strains on tobacco leaves：（1） an indigenous strain, Pseudomonas stutzeri Nov. Y2011 labeled with green fluorescent protein, and （2） an immigrant strain Pantoea agglomerans labeled with cyan fluorescent protein isolated from pear, were studied. Under moist conditions, P. agglomerans cells quickly disappeared from direct observation by laser- scanning confocal microscopy, although elution results indicated that large amounts of live cells were still present on the leaves. Following exposure to desiccation stress, particles of cyan fluorescent protein-labeled P. agglomerans were visible within cracked aggregates of P. stutzeri Nov. Y2011. Detailed observation of sectioned aggregates showed that colonies of immigrant P. agglomerans were embedded within aggregates of P. stutzeri Nov. Y2011. Furthermore, carbon-resource partitioning studies suggested that these two species could coexist without significant nutritional competition. This is the first observation of an immigrant bacterium embedding within aggregates of indigenous bacteria on leaves to evade harsh conditions in the phyllosphere.

关键词： phyllosphere spatial organization epiphytes survival manner

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Recent advances in the development of nanomaterials for DC-based immunotherapy

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Science Bulletin 2016年第7期61卷 514-523页

作者： Ligeng Xu Jian Xiang Rui peng zhuang Liu Institute of Functional Nano and Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Soochow University

As professional antigen presenting cells, dendritic cells(DCs) greatly determine the quality of the innate and adaptive immunities. Therefore, DC-based immunotherapy has been one of the hotspots in cancer immunotherapy in recent years. Although this unique therapeutic strategy has been approved by U.S. Food and Drug Administration for prostate cancer treatment, the efficacy of DC-based immunotherapy remains to be further improved. Moreover, it is still not completely clear about the immunological basis of DCs, which is another hurdle for the progress of DC-based immunotherapy. Due to their unique physicochemical properties, nanomaterials have shown potentials in addressing these above mentioned problems and have provided important guidelines for optimizing DC-based immunotherapy. However, it is still at the starting stage for this emerging field and there are many critical questions in the rational design of this therapeutic strategy to be answered. Therefore, it is greatly necessary to review and analyze recent progresses in this field. In this review, we mainly focus on the development of various types nanoparticles for DC-based immunotherapy. The existed challenges in this field are also discussed.

关键词： Dendritic cells Immunotherapy Cancer vaccine Tracking Nanomaterials

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Design and Performance Analysis of Axial Flux Permanent Magnet Machines with Double-Stator Dislocation Using a Combined Wye-Delta Connection

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CES Transactions on Electrical Machines and Systems 2022年第1期6卷 53-59页

作者： Bing peng Xiaoyu zhuang College of Electrical Engineering Shenyang University of TechnologyShenyang110023China

Conventional fractional slot concentrated winding three-phase axial flux permanent magnet machines have an abundance of armature reaction magnetic field harmonics which deteriorate the torque performance of the *** paper presents a double-stator dislocated axial flux permanent magnet machine with combined wye-delta winding.A wye-delta(Y-△)winding connection method is designed to eliminate the 6 th ripple torque generated by air gap magnetic field ***,the accurate subdomain method is adopted to acquire the no-load and armature magnetic fields of the machine,respectively,and the magnetic field harmonics and torque performance of the designed machine are ***,a 6 k W,4000 r/min,18-slot/16-pole axial flux permanent magnet machine is *** finite element simulation results show that the proposed machine can effectively eliminate the 6 th ripple torque and greatly reduce the torque ripple while the average torque is essentially identical to that of the conventional three-phase machines with wye-winding connection.

关键词： Axial flux permanent magnet machine combined star-delta winding double-stator dislocation accurate subdomain model

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A Self-consistent Treatment of Disoriented Chiral Condensates

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Chinese Physics Letters 1998年第10期15卷 708-710页

作者： zhuang peng-fei Rolf Fauser Department of Physics Tsinghua UniversityBeijing 100084 Theoretical Physics Group Gesellschaft fr Schwerionenforschung GSID-64291 DarmstadtGermany

A system with disoriented chiral condensates(DCCs)is considered in the presence of residual thermal pion *** self-consistently solving the coupled equations for the condensates,the thermal pion distributions,and the s... 详细信息

关键词： neutral Chiral thermal

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Equal-Time Transport Theory for Scalar Particles with Width

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Chinese Physics Letters 1999年第5期16卷 330-332页

作者： zhuang peng-fei Rolf Fauser Department of Physics Tsinghua UniversityBeijing 100084 Theoretical Physics Group Gesellschaft für Schwerionenforschang GSID-64291 DarmstadtGermany

For a Ф^(4)-theory the equal-time transport theory is derived with a collision term by including 4-point *** aћexpansion a set of coupled equations is presented for the first three energy moments of the Wigner functions and the 4-point *** presence of 4-point *** limit n→0 is *** the collision term leads already in this limit to particles with width.

关键词： limit collision theory

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Numerical and experimental study of bleed impact in multistage axial compressors

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Chinese Journal of Aeronautics 2023年第2期36卷 1-16页

作者： Baojie LIU Xinwei zhuang Guangfeng AN Xianjun yu Research Institute of Aero-Engine Beihang UniversityBeijing 100191China National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics Beijing 100191China School of Energy and Power Engineering Beihang UniversityBeijing 100191China

In this study,the influence of inter-stage bleeding on the compressor performance and inter-stage flow field of a multistage axial compressor is investigated by both experimental and numerical *** experiment is conducted on a four-stage low-speed axial compressor,and a specific computational model is built to simulate the experiment environment *** illuminate the fluid mechanisms of bleeding effect in detail,both the experiment and the simulation are carried out twice,i.e.,in the first time,the mass flow rate upstream the bleed location is constant under different bleed rate conditions;while in the second time,the mass flow rate downstream the bleed location is constant under different bleed rate *** results demonstrate that inter-stage bleeding has little influence on upstream compressor characteristics,and affects the upstream flow field only in the rear half of the *** bleed effect on the downstream flow field is embodied in the variation of an incoming flow profile,an increase as the compressor inlet flow coefficient ***,such an effect is only significant on compressor characteristics at small flow coefficient *** multistage compressors,the variation of compressor characteristics and flow field caused by inter-stage bleeding is the comprehensive result of the bleeding and the variation of the upstream working *** addition,the comparison between numerical and experimental results shows that the flow moves towards top half of span through the downstream rotor passage in the numerical simulation,whereas the trend of flow field variation with different bleed rates at the outlet of the downstream rotor and stator is the same with that at the inlet of the downstream rotor in the experiment,which means that the numerical method has overestimated the radial mixing intensity of the flow.

关键词： Compressor characteristics Inter-stage bleeding Low-speed compressor experiment Multistage axial compressor Spanwise mixing

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Differential Expression of Rice Genes Under Different Nitrogen Forms and Their Relationship with Sulfur Metabolism

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Journal of Integrative Plant Biology 2006年第10期48卷 1177-1184页

作者： Guo-Hui Zhu Chu-Xiong zhuang yu-Oi Wang Lin-Rong Jiang Xin-Xiang peng College of Life Sciences South China Agricultural University Guangzhou 510642 China

Microarray analysis was initially performed to screen for differentially expressed genes between nitrate-and ammonium-fed rice （Oryza sativa L.） leaves, in total, 198 genes were shown to have a unique expression response to each treatment and most of the genes for which function is known were involved in signal transduction, plant stress resistance, transcriptional regulation, and basic metabolism. Northern blotting analysis confirmed that expression of the MT and PCS genes was highly upregulated in ammonium-fed leaves compared with expression in nitrate-fed leaves and it was further revealed that ammonium-fed leaves accumulated more cysteine and glutathione. The upregulated expressions of the MTand PCS genes and the higher levels of cysteine and glutathione in ammonium-fed leaves indicate that ammonium may be able to accelerate sulfur assimilation metabolism in rice leaves. Unexpectedly, Northern blotting analysis showed that the expression of the two key enzymes in the sulfur assimilation pathway, namely adenosine 5＇-phosphosulfate reductase and O-acetylserine（thiol）lyase, was not upregulated by ammonium treatment. It was found that the total content of free amino acids was much higher in ammonium-fed leaves compared with nitrate-fed leaves, mainly resulting from an increase in several amino acids such as serine, asparagine, glutamine, and arginine. The increased amino acids, in particular serine （as a central substrate for the synthesis of the thioi metabolites）, may have promoted sulfur assimilation metabolism under conditions of ammonium nutrition.

关键词： gene expression nitrogen forms rice sulfur assimilation

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