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Tunable magneto-Seebeck effect in Co_(2)FeSi/MgO/Co_(2)FeSi heterostructure via optimized interfacial engineering

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Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 128-135页

作者： Jingyu Li Xianbiao Shi Yurong Jin Le Ma liuming Wei Chi Zhang Hang Li peng-fei liu International Joint Research Laboratory of New Energy Materials and Devices of Henan Province School of Physics and ElectronicsHenan UniversityKaifeng 475004China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Spallation Neutron Source Science Center Dongguan 523803China Defence Industry Secrecy Examination and Certification Center Beijing 100089China School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China Department of Network Security Henan Police CollegeZhengzhou 450046China College of Electrical Engineering Henan University of TechnologyZhengzhou 450001China

Enhancing the tunneling magneto-Seebeck(TMS) ratio and uncovering its underlying mechanism are greatly demanded in spin *** magnitude and sign of the TMS effect depend on the type of atom and the stacking order of atoms at the ***,we demonstrate that TMS ratios can be effectively manipulated by altering heterogonous or homogeneous interface through decoration on the CoFeSi(001) surface inserted on the MgO insulating *** maximum TMS ratio of pure Co_(2)/O termination is 4565% at 800 ***,the TMS ratio of the FeSi/O termination has two peak values,of which the maximum could reach up to-3290% at 650 *** comparing two different atom arrangements at the interface,we reveal that the sign and symbol of the TMS ratio can be controlled by the temperature and different atomic configurations at the Co_(2)FeSi/MgO ***,the spin-Seebeck coefficient up to ~150 μV/K is also possible when we select suitable terminations and *** findings will provide useful insights into how to control the sign and symbol of the TMS ratio and accordingly stimulate the development field of magneto-thermoelectric power and spin caloritronic devices based on the magneto-Seebeck effect in Heusler-based metallic multilayers.

关键词： magneto-Seebeck effect interface spintronics electronic structure spin-Seebeck effect

Establishment of a prognosis predictive model for liver cancer based on expression of genes involved in the ubiquitin-proteasome pathway

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World Journal of Clinical Oncology 2024年第3期15卷 434-446页

作者： Hua Li Yi-Po Ma Hai-Long Wang Cai-Juan Tian Yi-Xian Guo Hong-Bo Zhang Xiao-Min liu peng-fei liu Department of Endoscopy Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and Therapy of TianjinTianjin’s Clinical Research Center for CancerTianjin 300060China Department of Critical Care Medicine Dingzhou City People’s HospitalDingzhou 073000Hebei ProvinceChina Department of Oncology Tianjin Academy of Traditional Chinese Medicine Affiliated HospitalTianjin 300120China Tianjin Marvel Medical Laboratory Tianjin Marvelbio Technology Co.LtdTianjin 300180China Department of Intelligent Technology Tianjin Yunquan Intelligent Technology Co.LtdTianjin 300381China Department of Oncology Tianjin Huanhu HospitalTianjin 300350China

BACKGROUND The ubiquitin-proteasome pathway(UPP)has been proven to play important roles in *** To investigate the prognostic significance of genes involved in the UPP and develop a predictive model for liver cancer based on the expression of these *** In this study,UPP-related E1,E2,E3,deubiquitylating enzyme,and proteasome gene sets were obtained from the Kyoto Encyclopedia of Genes and Genomes(KEGG)database,aiming to screen the prognostic genes using univariate and multivariate regression analysis and develop a prognosis predictive model based RESULTS Five genes(including autophagy related 10,proteasome 20S subunit alpha 8,proteasome 20S subunit beta 2,ubiquitin specific peptidase 17 like family member 2,and ubiquitin specific peptidase 8)were proven significantly correlated with prognosis and used to develop a prognosis predictive model for liver *** training,validation,and Gene Expression Omnibus sets,the overall survival differed significantly between the high-risk and low-risk *** expression of the five genes was significantly associated with immunocyte infiltration,tumor stage,and postoperative recurrence.A total of 111 differentially expressed genes(DEGs)were identified between the high-risk and low-risk groups and they were enriched in 20 and 5 gene ontology and KEGG *** division cycle 20,Kelch repeat and BTB domain containing 11,and DDB1 and CUL4 associated factor 4 like 2 were the DEGs in the E3 gene set that correlated with *** We have constructed a prognosis predictive model in patients with liver cancer,which contains five genes that associate with immunocyte infiltration,tumor stage,and postoperative recurrence.

关键词： Liver cancer Ubiquitin-proteasome pathway Prognosis prediction Gene expression Immune infiltration

钼活化ZnIn_(2)S(4)光催化剂促进光催化析氢耦合苯甲醇氧化

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Science China Materials 2024年第8期67卷 2645-2652页

作者：俞杨帆尤晓萌张阳彭玉王雪璐刘鹏飞杨化桂 Key Laboratory for Ultrafine Materials of Ministry of Education Shanghai Engineering Research Center of Hierarchical NanomaterialsSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China Physics Department&Shanghai Key Laboratory of Magnetic Resonance School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200062China

光催化水裂解制氢为解决能源危机提供了一条可行的途径.然而,四电子的水氧化反应迟缓严重制约了水的分解效率.本文中,掺杂Mo的ZnIn_(2)S(4);(Mo-ZIS)光催化剂通过与动力学上有利的苯甲醇(BA)的氧化反应协同整合,显著促进了析氢反应,高... 详细信息

光催化水裂解制氢为解决能源危机提供了一条可行的途径.然而,四电子的水氧化反应迟缓严重制约了水的分解效率.本文中,掺杂Mo的ZnIn_(2)S(4);(Mo-ZIS)光催化剂通过与动力学上有利的苯甲醇(BA)的氧化反应协同整合,显著促进了析氢反应,高价和不饱和Mo不仅促进光生载流子的分离,还促进BA的活化,从而加速BA的氧化.此外,Mo掺杂调节了ZIS的能带结构,增强了光催化剂的氧化能力,而不会引起BA的过度氧化.结果表明,Mo-ZIS光催化剂在不需要贵金属助催化剂的情况下,具有较高的析氢速率(16,353μmol g^(-1)h^(-1))和苯甲醛产率(13,942μmol g^(-1)h^(-1)),显著优于ZIS光催化剂.引人注意的是,通过调节BA与溶剂之间的氢键网络强度来调节中间体在Mo-ZIS表面的解吸过程,Mo-ZIS的BAD产率为23,068μmol g^(-1)h^(-1),相比于乙腈溶液中的反应速率提高了65%.本研究提出了一种有价值的将光催化制氢与选择性有机产物转化相结合的策略,为开发新型光催化剂,实现高效太阳能转化提供了新的见解.

关键词：光催化剂氢键网络析氢反应光生载流子过度氧化反应迟缓能源危机解吸过程

XRCC1 Polymorphisms and Pancreatic Cancer:A Meta-Analysis

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Chinese Journal of Cancer Research 2011年第3期23卷 165-170页

作者： Wei-dong Shen Hong-lin Chen peng-fei liu Department of Gastroenterology the Affiliated Jiangyin Hospital of Nantong UniversityJiangyin 214400China Nantong University School of Nursing Nantong 226001China

Objective：To assess the association between X-ray repair cross-complementating group 1 （XRCC1） polymorphisms and pancreatic ***：We searched MEDLINE,Web of Science and HuGE Navigator at June 2010,and then quantitatively summarized associations of the XRCC1 polymorphisms with pancreatic cancer risk using ***：Four studies with 1343 cases and 2302 controls were *** analysis found：at codon 194,the Trp allele did not decrease pancreatic cancer risk （Arg/Arg versus Trp/Trp：OR=0.97;95% CI：0.48-1.96;P=0.97;Arg/Arg versus Arg/Trp：OR=0.89;95% CI：0.70-1.13;P=0.55;Arg/Trp versus Trp/Trp：OR=1.06;95% CI：0.52-2.16;P=0.90）;at codon 280,only a study showed a nonsignificant association between single nucleotide polymorphism with pancreatic cancer risk;at codon 399,the Gln allele also showed no signi？cant effect on pancreatic cancer compared to Arg allele （Arg/Arg versus Gln/Gln：OR=0.94;95% CI：0.74-1.18;Arg/Arg versus Arg/Gln：OR=0.97;95% CI：0.83-1.13;Arg/Gln versus Gln/Gln：OR=0.97;95% CI：0.77-1.22）.The shape of the funnel plot and the Egger＇s test did not detect any publication ***：There is no evidence that XRCC1 polymorphisms （Arg194Trp,Arg280His,and Arg399Gln） are associated with pancreatic cancer risk.

关键词： Pancreatic cancer X-ray repair cross-complementating group 1 Gene polymorphism Meta-analysis Molecular epidemiology

EGFR gene copy number as a predictive biomarker for resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer treatment:a meta-analysis

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Chinese Journal of Cancer Research 2014年第1期26卷 59-71页

作者： Wei-Dong Shen Hong-Lin Chen peng-fei liu Department of Gastroenterology the Affiliated Jiangyin Hospital of Nantong University Nantong University

Objective：The epidermal growth factor receptor （EGFR） inhibitors monoclonal antibodies （MoAbs） have already shown the therapeutic effectiveness in patients with metastatic colorectal cancer （mCRC）.But many patients resist to the *** aim of this meta-analysis was to assess EGFR gene copy number （GCN） as a candidate predictive biomarker for resistance to anti-EGFR MoAbs in mCRC ***：Systematic computerized searches of the PubMed,EMBase and Cochrane Library were *** primary endpoint was objective response rate （ORR）.The second endpoints included progression-free survival （PFS）,and overall survival （OS）.The pooled odd ratio （OR） and pooled sensitivity,specificity,and summary receiver operator characteristic （SROC） for ORR were *** pooled hazard ratios （HR） for PFS and OS were also ***：Fourteen studies with 1,021 patients were *** EGFR GCN was associated with increased ORR （OR=6.905; 95％ CI：4.489-10.620）.It was also found in wild-type KRAS mCRC patients,with the pooled OR of 8.133 （95 ％ CI：4.316-15.326）.GCN has medium value for predicting ORR,with the pooled sensitivity of 0.79 （95％ CI：0.73-0.84）,the pooled specificity of 0.59 （95％ CI：0.55-0.62）.In wildtype KRAS mCRC patients,the sensitivity and the specificity were 0.80 （95％ CI：0.70-0.87） and 0.60 （95％CI：0.53-0.66）,*** EGFR GCN was associated with increased PFS （HR=0.557; 95％ CI：0.382-0.732） and OS （HR=0.579; 95％ CI：0.422-0.737）.Conclusions：This meta-analysis suggests that EGFR GCN represents a predictive biomarker for tumor response in mCRC patients treated with MoAbs regardless of KRAS *** patients with increased EGFR GCN are more likely to have a better response,PFS,and OS when treated with cetuximab or panitumumab.

关键词： Metastatic colorectal cancer (mCRC) epidermal growth factor receptor (EGFR) gene copy number (GCN) meta-analysis

New Discoveries of Domination Between Traffic Matrices

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Acta Mathematicae Applicatae Sinica 2017年第3期33卷 561-566页

作者： peng-fei liu Wen-guo YANG Tian-de GUO School of Mathematics Sciences University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Big Data Mining and Knowledge Management Chinese Academy of SciencesBeijing 100049China

In this paper the definition of domination is generalized to the case that the elements of the traffic matrices may have negative values. It is proved that D3 dominates D3 ＋ λ（D2 - D1） for any λ ≥0 if D1 dominates D2. Let u（D） be the set of all the traffic matrices that are dominated by the traffic matrix D. It is shown that u （ D∞） and u （D ∈） are isomorphic. Besides, similar results are obtained on multi-commodity flow problems. Fhrthermore, the results are the generalized to integral flows.

关键词： robust network design multi-commodity flows domination

Optimal design of pressure vessel using an improved genetic algorithm

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第9期9卷 1264-1269页

作者： peng-fei liu Ping XU Shu-xin HAN Jin-yang ZHENG Institute of Chemical Machinery and Process Equipment Zhejiang University Hangzhou 310027 China Institute of Applied Mechanics Zhejiang University Hangzhou 310027 China Hangzhou Special Equipment Inspection Institute Hangzhou 310003 China

As the idea of simulated annealing (SA) is introduced into the fitness function, an improved genetic algorithm (GA) is proposed to perform the optimal design of a pressure vessel which aims to attain the minimum weight under burst pressure con- straint. The actual burst pressure is calculated using the arc-length and restart analysis in finite element analysis (FEA). A penalty function in the fitness function is proposed to deal with the constrained problem. The effects of the population size and the number of generations in the GA on the weight and burst pressure of the vessel are explored. The optimization results using the proposed GA are also compared with those using the simple GA and the conventional Monte Carlo method.

关键词： Pressure vessel Optimal design Genetic algorithm (GA) Simulated annealing (SA) Finite element analysis (FEA)

Wave action by arrays of vertical cylinders with arbitrary smooth cross-section

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Journal of Hydrodynamics 2020年第1期32卷 70-81页

作者： Jia-bin liu An-xin Guo Qing-he Fang Hui Li Hui Hu peng-fei liu Key Lab of Structures Dynamic Behavior and Conrol of the Ministry of Education Harbin Institute of Techno-logyHarbin 150090China Key Lab of Smart Prevention and Mitigation of Civil Engineering Disasters of the Ministry of Industry and Information Technology Harbin Institute of TechnologyHarbin 150090China Depariment of Aerospace Engineering lowa State UniversityAmeslowa 50011USA China Railway Bridge Science Research Institute LtdWuhan 430034China

This paper presents an analytical model to solve the linear wave diffraction problem by arrays of bottom-mounted cylinders with arbitrary smooth *** on the assumption of ideal fluid and potential theory,the unknown coefficients of total velocity potential can be solved by system of linear equations,which are obtained from the boundary *** accuracy of the present method is verified by comparing it with the numerical tool in terms of the wave force and wave *** cylinders with different configurations are tested,the cross-section of which is circular with cosine *** results show that the proposed method could obtain an accurate prediction of the wave action with multiple cylinder ***,the diffraction wave is investigated on arrays of bottom-mounted cylinders with different cross-section and *** near-trapping problem with effects of the multi-body interaction are also investigated.

关键词： Wave diffraction cylinder array arbitrary smooth cross-section analytical solution

Design and Analysis of a Novel 2T2R Parallel Mechanism with the Closed-loop Limbs

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International Journal of Automation and computing 2021年第4期18卷 654-666页

作者： Hai-Rong Fang peng-fei liu Hui Yang Bing-Shan Jiang School of Mechanical Electronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China

This paper presents a novel four degrees of freedom(DOF) parallel mechanism with the closed-loop limbs, which includes two translational(2 T) DOF and two rotational(2 R) DOF. By connecting the proposed parallel mechanism with the guide rail in series,the 5-DOF hybrid robot system is obtained, which can be applied for the composite material tape laying in aerospace industry. The analysis in this paper mainly focuses on the parallel module of the hybrid robot system. First, the freedom of the proposed parallel mechanism is calculated based on the screw theory. Then, according to the closed-loop vector equation, the inverse kinematics and Jacobian matrix of the parallel mechanism are carried out. Next, the workspace stiffness and dexterity analysis of the parallel mechanism are investigated based on the constraint equations, static stiffness matrix and Jacobian condition number. Finally, the correctness of the inverse kinematics and the high stiffness of the parallel mechanism are verified by the kinematics and stiffness simulation analysis, which lays a foundation for the automatic composite material tape laying.

关键词： 2T2R parallel mechanism close loop structure high stiffness kinematics analysis workspace