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Versatile photonic molecule switch in multimode microresonators

Light(Science & Applications) 2024年第3期13卷 498-509页

作者： z.han Tao Bitao Shen Wencan Li Luwen Xing Haoyu Wang Yichen Wu Yuansheng Tao Yan z.ou Yandong He Chao peng Haowen Shu Xingjun Wang State Key Laboratory of Advanced Optical Communications System and Networks School of ElectronicsPeking UniversityBeijing 100871China College of Engineering Peking UniversityBeijing 100871China School of Integrated Circuits Peking University100871 BejingChina Peking University Yangtz. Delta Institute of Optoelectronics Nantong 226010China Frontiers Science Center for Nano-optoelectronics Peking UniversityBeijing 100871China peng Cheng Laboratory Shenzhen 518055China

Harnessing optical supermode interaction to construct artificial photonic molecules has uncovered a series of fundamental optical phenomena analogous to atomic ***,the distinct energy levels and interactions in such two-level systems were provided by coupled *** reconfigurability is limited,as they often require delicate external field stimuli or mechanically altering the geometric *** highly specific approaches also limit potential ***,we propose a versatile on-chip photonic molecule in a multimode microring,utiliz.ng a flexible regulation methodology to dynamically control the existence and interaction strength of spatial *** transition between single/multi-mode states enables the“switched-off/on”functionality of the photonic molecule,supporting wider generaliz.d applications *** particular,“switched-on”state shows flexible and multidimensional mode splitting control in aspects of both coupling strength and phase difference,equivalent to the *** *** effect.“Switched-off”state allows for perfect low-loss single-mode transition(Qi~10 million)under an ultra-compact bend siz.(FSR~115 GHz.in a foundry-based silicon *** breaks the stereotyped image of the FSR-Q factor trade-off,enabling ultra-wideband and high-resolution millimeter-wave photonic *** demonstration provides a flexible and portable solution for the integrated photonic molecule system,extending its research scope from fundamental physics to real-world applications such as nonlinear optical signal processing and sixth-generation wireless communication.

关键词： switched multimode millimeter

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Dynamic immune recovery process after liver transplantation revealed by single-cell multi-omics analysis

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The Innovation 2024年第3期5卷 55-68页

作者： Rui Wang Xiao peng Yixin Yuan Baojie Shi Yuan Liu Hengxiao Ni Wenz.i Guo Qiwei Yang Pingguo Liu Jie Wang z.aojie Su Shengnan Yu Dehua Liu Jinyan z.ang Junjie Xia Xueni Liu Hao Li z.engfeng Yang z.ihai peng Organ Transplantation Clinical Medical Center of Xiamen University Department of General SurgeryXiang’an Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamen 361102China Organ Transplantation Institute of Xiamen University Xiamen Human Organ Transplantation Quality Control CenterXiamen Key Laboratory of Regeneration MedicineFujian Provincial Key Laboratory of Organ and Tissue RegenerationSchool of MedicineXiamen UniversityXiamen 361102China Department of General Surgery Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China State Key Laboratory of Cellular Stress Biology School of Life SciencesFaculty of Medicine and Life SciencesXiamen UniversityXiamen 361102China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000China Department of Hepatobiliary&Pancreatic Surgery The National Key Clinical SpecialtyZhongshan Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamen 361102China Precision Research Center for Refractory Diseases Institute for Clinical ResearchShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 201620China

Elucidating the temporal process of immune remodeling under immunosuppressive treatment after liver transplantation(LT)is critical for precise clinical management ***,we performed a single-cell multi-omics analysis of peripheral blood mononuclear cells(PBMCs)collected from LT patients(with and without acute cellular rejection[ACR])at 13 time *** was performed in two independent cohorts with additional LT patients and healthy *** study revealed a four-phase recovery process after LT and delineated changes in immune cell composition,expression programs,and interactions along this *** intensity of the immune response differs between the ACR and non-ACR ***,the newly identified inflamed NK cells,CD14+RNASE2+monocytes,and FOS-expressing monocytes emerged as predictive indicators of *** study illuminates the longitudinal evolution of the immune cell landscape under tacrolimus-based immunosuppressive treatment during LT recovery,providing a four-phase framework that aids the clinical management of LT patients.

关键词： process analysis precise

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Staphylococcus aureus and biofilms:transmission, threats, and promising strategies in animal husbandry

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1408-1423页

作者： Mengda Song Qi Tang Yakun Ding peng Tan Yucheng z.ang Tao Wang Chenlong z.ou Shenrui Xu Mengwei Lyu Yueyu Bai Xi Ma State Key Laboratory of Animal Nutrition and Feeding College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Key Laboratory of Innovative Utiliz.tion of Local Cattle and Sheep Germplasm Resources(Co‑Construction by Ministry and Province) Ministry of Agriculture and Rural AffairsSchool of Agricultural SciencesZhengzhou UniversityZhengzhou 450001China

Staphylococcus aureus(S. aureus) is a common pathogenic bacterium in animal husbandry that can cause diseases such as mastitis, skin infections, arthritis, and other ailments. The formation of biofilms threatens and exacerbates S. aureus infection by allowing the bacteria to adhere to pathological areas and livestock product surfaces, thus triggering animal health crises and safety issues with livestock products. To solve this problem, in this review, we provide a brief overview of the harm caused by S. aureus and its biofilms on livestock and animal byproducts(meat and dairy products). We also describe the ways in which S. aureus spreads in animals and the threats it poses to the livestock industry. The processes and molecular mechanisms involved in biofilm formation are then explained. Finally, we discuss strategies for the removal and eradication of S. aureus and biofilms in animal husbandry, including the use of antimicrobial peptides, plant extracts, nanoparticles, phages, and antibodies. These strategies to reduce the spread of S. aureus in animal husbandry help maintain livestock health and improve productivity to ensure the ecologically sustainable development of animal husbandry and the safety of livestock products.

关键词： Animal husbandry Biofilm Mastitis Mitigation strategies Staphylococcus aureus

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Polymer engineering for electrodes of aqueous z.nc ion batteries

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Journal of Energy Chemistry 2024年第4期91卷 345-369页

作者： z.i peng z.min Feng Xuelian z.ou Siwen Li Xuejing Yin z.kun z.ang Ningning z.ao z.angxing He Lei Dai Ling Wang Chao Lu School of Chemical Engineering North China University of Science and TechnologyTangshan 063210HebeiChina State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing 100029China

With the increasing demand for scalable and cost-effective electrochemical energy storage,aqueous z.nc ion batteries(Az.Bs)have a broad application prospect as an inexpensive,efficient,and naturally secure energy storage ***,the limitations suffered by Az.Bs,including volume expansion and active materials dissolution of the cathode,electrochemical corrosion,irreversible side reactions,z.nc dendrites of the anode,have seriously decelerated the civilianiz.tion process of ***,polymers have tremendous superiority for application in Az.Bs attributed to their exceptional chemical stability,tunable structure,high energy density and outstanding mechanical *** the expanding applications of Az.Bs and the superiority of polymers,this comprehensive paper meticulously reviews the benefits of utiliz.ng polymeric applied to cathodes and anodes,*** begin with,with adjustable structure as an entry point,the correlation between polymer structure and the function of energy storage as well as optimiz.tion is deeply investigated in respect to the ***,depending on the diversity of properties and structures,the development of polymers in Az.Bs is summariz.d,including conductive polymers,redox polymers as well as carbon composite polymers for cathode and polyvinylidene fluoride-,carbonyl-,amino-,nitrile-based polymers for anode,and a comprehensive evaluation of the shortcomings of these strategies is ***,an outlook highlights some of the challenges posed by the application of polymers and offers insights into the potential future direction of polymers in *** is designed to provide a thorough reference for researchers and developers working on polymer for Az.Bs.

关键词： Aqueous z.nc ion batteries Polymer Multi-function Anode protection Energy storage

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Atomically dispersed calcium as solid strong base catalyst with high activity and stability

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Green Energy & Environment 2024年第10期9卷 1619-1626页

作者： Xiang-Bin Shao z.i-Wei Xing Si-Yu Liu Ke-Xin Miao Shi-Chao Qi Song-Song peng Xiao-Qin Liu Lin-Bing Sun State Key Laboratory of Materials-Oriented Chemical Engineering Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM)College of Chemical EngineeringNanjing Tech University30 South Puzhu Road

Solid strong base catalysts are highly attractive for diverse reactions owing to their advantages of neglectable corrosion,facile separation,and environmental ***,their widespread applications are impeded by basic components aggregation and low *** this work,we fabricate single calcium atoms on graphene （denoted as Ca1/G） by use of a redox strategy for the first time,producing solid strong base catalyst with high activity and *** precursor Ca（NO3）2is first reduced to CaO at 400℃ by the support graphene,forming CaO/G with conventional basic sites,and the subsequent reduction at 850℃ results in the generation of Ca1/G with atomically dispersed *** characteriz.tions reveal that Ca single atoms are anchored on graphene in tetra-coordination （Ca–C2–N2） where N is in situ doped from Ca（NO3）*** atomically dispersed Ca,along with their anchoring on the support,endow Ca1/G with high activity and stability toward the transesterification reaction of ethylene carbonate with *** turnover frequency value reaches 128.0 h-1on Ca1/G,which is much higher than the traditional counterpart CaO/G and various reported solid strong bases (2.9–46.2 h-1).Moreover,the activity of Ca1/G is well maintained during 5 cycles,while 60% of activity is lost for the conventional analogue CaO/G due to the leaching of Ca.

关键词： Solid strong base Single Ca atoms Heterogeneous catalysts Transesterification Reaction

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Microvesicles derived from mesenchymal stem cells inhibit acute respiratory distress syndrome-related pulmonary fibrosis in mouse partly through hepatocyte growth factor

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World Journal of Stem Cells 2024年第8期16卷 811-823页

作者： Qi-Hong Chen Ying z.ang Xue Gu peng-Lei Yang Jun Yuan Li-Na Yu Jian-Mei Chen Department of Critical Care Medicine Jiangdu People’s Hospital of YangzhouJiangdu People’s Hospital Affiliated to Yangzhou UniversityYangzhou 225200Jiangsu ProvinceChina Department of Critical Care Medicine Jiangdu People’s Hospital of YangzhouYangzhou 225200Jiangsu ProvinceChina Institute of Translational Medicine Medical CollegeYangzhou UniversityYangzhou 225000Jiangsu ProvinceChina

BACKGROUND Pulmonary fibrosis is one of the main reasons for the high mortality rate among acute respiratory distress syndrome(ARDS)*** stromal cell-derived microvesicles(MSC-MVs)have been shown to exert antifibrotic effects in lung *** To investigate the effects and mechanisms of MSC-MVs on pulmonary fibrosis in ARDS mouse *** MSC-MVs with low hepatocyte growth factor(HGF)expression(siHGF-MSC-MVs)were obtained via lentivirus transfection and used to establish the ARDS pulmonary fibrosis mouse *** intubation,respiratory mechanics-related indicators were measured via an experimental small animal lung function *** of MSC-MVs in lung tissues was investigated by near-infrared live ***,western blotting,ELISA and other methods were used to detect expression of pulmonary fibrosis-related proteins and to compare effects on pulmonary fibrosis and fibrosis-related *** The MSC-MVs gradually migrated and homed to damaged lung tissues in the ARDS model *** with MSC-MVs significantly reduced lung injury and pulmonary fibrosis ***,low expression of HGF(siHGF-MSC-MVs)significantly inhibited the effects of MSC-MVs(P<0.05).Compared with the ARDS pulmonary fibrosis group,the MSC-MVs group exhibited suppressed expression of type I collagen antigen,type III collagen antigen,and the proteins transforming growth factor-βandα-smooth muscle actin,whereas the siHGF-MVs group exhibited significantly increased expression of these *** addition,pulmonary compliance and the pressure of oxygen/oxygen inhalation ratio were significantly lower in the MSC-MVs group,and the effects of the MSC-MVs were significantly inhibited by low HGF expression(all P<0.05).CONCLUSION MSC-MVs improved lung ventilation functions and inhibited pulmonary fibrosis in ARDS mice partly via HGF mRNA transfer.

关键词： Microvesicles derived from mesenchymal stem cells Acute respiratory distress syndrome Pulmonary fibrosis Hepatocyte growth factor Mesenchymal stromal cells

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The Role of Renewable Protocatechol Acid in Epoxy Coating Modification: Significantly Improved Antibacterial and Adhesive Properties

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Chinese Journal of Polymer Science 2024年第1期42卷 63-72,I0008页

作者： Ming-Xuan Chen Jin-Yue Dai Li-Yue z.ang Shuai-peng Wang Jing-Kai Liu Yong-Gang Wu Xin-Wu Ba Xiao-Qing Liu School of Chemistry and Materials Science Hebei UniversityBaoding 071000China Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China Key Laboratory of Marine Materials and Related Technologies Chinese Academy of SciencesNingbo 315201China

It is of great significance to design epoxy coatings with superior antibacterial properties and high adhesive properties, as well as excellent processing, superior durability, and high transparency. However, it is still a challenge because of the common complex design and synthesis. Herein, the bio-based monomer protocatechuic acid(PCA) was used as raw material, the catechol structure with high bonding and antibacterial properties was introduced into the flexible alkane segment of ethylene glycol diglycidyl ether(EGDE) through an efficient, and green method, and it was cured with isophorone diamine(IPDA) to prepare corresponding thermosets. The cured resins exhibited excellent allaround qualities, particularly in bonding and antibacterial. When 30% PCA was added to pure epoxy resin, the adhesion between substrate and coating increased from 4.40 MPa to 13.60 MPa and the antibacterial rate of coating against E. coli and S. aureus could approach 100%. All of this is due to the fact that the catechol structure present in PCA has the ability to interact with various substrates and alter the permeability of bacterial cell membranes. The architecture of this method offers a fresh approach to dealing with the issues of challenging raw material selection and complex synthesis techniques.

关键词： Epoxy coatings Thermosets Catechol structure Antibacterial High adhesion

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Genomic variation,environmental adaptation,and feraliz.tion in ramie,an ancient fiber crop

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Plant Communications 2024年第8期5卷 189-207页

作者： z.ng-Yuan Wu Mark A.Chapman Jie Liu Richard I.Milne Ying z.ao Ya-Huang Luo Guang-Fu z.u Marc W.Cadotte Ming-Bao Luan peng-z.en Fan Alex K.Monro z.i-peng Li Richard T.Corlett De-z.u Li Germplasm Bank of Wild Species&Yunnan Key Laboratory of Crop Wild Relatives Omics Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China School of Biological Sciences University of SouthamptonSouthampton SO171BJUK CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China Institute of Molecular Plant Sciences School of Biological SciencesUniversity of EdinburghEdinburgh EH93JHUK Department of Biological Sciences University of Toronto-ScarboroughTorontoOntarioCanada Institute of Bast Fiber Crops Chinese Academy of Agricultural SciencesChangshaHunan 410205China Royal Botanic Gardens Kew RichmondSurrey TW93AEUK Center for Integrative Conservation and Yunnan Key Laboratory for the Conservation of Tropical Rainforests and Asian Elephants Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglunYunnan 666303China

Feraliz.tion is an important evolutionary process,but the mechanisms behind it remain poorly ***,we use the ancient fiber crop ramie(Boehmeria nivea(L.)Gaudich.)as a model to investigate genomic changes associated with both domestication and *** first produced a chromosome-scale de novo genome assembly of feral ramie and investigated structural variations between feral and domesticated ramie ***,we gathered 915 accessions from 23 countries,comprising cultivars,major landraces,feral populations,and the wild *** on whole-genome resequencing of these accessions,we constructed the most comprehensive ramie genomic variation map to ***,demographic,and admixture signal detection analyses indicated that feral ramie is of exoferal or exo-endo origin,i.e.,descended from hybridiz.tion between domesticated ramie and the wild progenitor or ancient *** ramie has higher genetic diversity than wild or domesticated ramie,and genomic regions affected by natural selection during feraliz.tion differ from those under selection during *** analyses showed that feral and domesticated ramie have similar ecological niches that differ substantially from the niche of the wild progenitor,and three environmental variables are associated with habitat-specific adaptation in feral *** findings advance our understanding of feraliz.tion,providing a scientific basis for the excavation of new crop germplasm resources and offering novel insights into the evolution of feraliz.tion in nature.

关键词： ramie fiber offering

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Lone-Star retractor perineal exposure method for laparoscopic abdominal perineal resection of rectal cancer

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2528-2537页

作者： Jun Ma Dai-Bin Tang Yu-Quan Tang Da-Tian Wang peng Jiang Ya-Ming z.ang Department of General Surgery Anqing Municipal HospitalAnqing 246000Anhui ProvinceChina Department of Anesthesiology Anqing Municipal HospitalAnqing 246000Anhui ProvinceChina

BACKGROUND The abdominal perineal resection(APR),historically referred to as Mile’s proce-dure,stands as a time-honored surgical intervention for rectal cancer *** in surgical techniques and the advent of neoadjuvant therapies have significantly improved the rate of sphincter preservation among patients afflicted with rectal cancer,including those with ultralow rectal *** these improvements,APR maintains its irreplaceable role in the clinical landscape,particularly for cases involving low rectal cancer with encroachment on the external anal sphincter or levator ani *** perineal exposure stands as a pivotal phase in APR,given that the precision of this maneuver is directly correlated with both the safety of the surgery and the patient’s subse-quent long-term *** To evaluate the value of Lone-Star retractor(LSR)perineal exposure method in the treatment for laparoscopic APR of rectal *** We reviewed the records of 38 patients with rectal cancer at Anqing Municipal Hospital from January 2020 to December 2023,including 20 patients who underwent the APR procedure with a LSR perineal exposure method(LSR group)and 18 patients who underwent the APR procedure with a conventional perineal exposure method(control group).In the LSR group,following incision of the skin and subcutaneous tissue,the LSR was placed and dynamically adjusted according to the surgical plane to fully expose the perineal operative *** A total of 38 patients underwent laparoscopic APR,none of whom were found to have distant metastasis upon intraoperative *** blood loss,the postoperative hospital stays and the wound pain scores in the LSR group were significantly lower than those in the control group.A single surgeon completed the perineal operation significantly more often in the LSR group than in the control group(P<0.05).The incidence of infection via the perineal incision in the LSR group was significantly lower

关键词： Rectal cancer Lone-Star retractor Abdominal perineal resection Perineal exposure method Technique

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Single crystal growth and characteriz.tion of 166-type magnetic kagome metals

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Chinese Physics B 2024年第9期33卷 145-150页

作者： Huangyu Wu Jinjin Liu Yongkai Li peng z.u Liu Yang Fuhong Chen Deng Hu z.iwei Wang Centre for Quantum Physics Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurement(MOE)School of PhysicsBeijing Institute of TechnologyBeijing 100081China Beijing Key Laboratory of Nanophotonics and Ultrafine Optoelectronic Systems Beijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Zhuhai 519000China Material Science Center Yangtze Delta Region Academy of Beijing Institute of TechnologyJiaxing 314011China

Kagome magnets were predicted to be a good platform to investigate correlated topology band structure,Chern quantum phase,and geometrical frustration due to their unique lattice *** we reported single crystal growth of 166-type kagome magnetic materials,including HfMn_(6)Sn_(6),z.Mn_(6)Sn_(6),GdMn_(6)Sn_(6)and GdV_(6)Sn_(6),by using the flux method with Sn as the *** them,HfMn_(6)Sn_(6)and z.Mn_(6)Sn_(6)single crystals were grown for the first time.X-ray diffraction measurements reveal that all four samples crystalliz. in HfFe6Ge6-type hexagonal structure with space group P6/*** samples show metallic behavior from temperature dependence of resistivity measurements,and the dominant carrier is hole,except for GdV6Sn6 which is electron *** samples have magnetic order with different transition temperatures,HfMn_(6)Sn_(6),z.Mn_(6)Sn_(6)and GdV_(6)Sn_(6)are antiferromagnetic with TN of 541 K,466 K and 4 K respectively,while GdMn_(6)Sn_(6)is ferrimagnetic with the critical temperature of about 470 *** study will enrich the research platform of magnetic kagome materials and help explore the novel quantum phenomena in these interesting *** dataset of specific crystal structure parameters for HfMn_(6)Sn_(6)are available in Science Data Bank,with the link.

关键词： kagome metal single crystal growth crystal structure physical property

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