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An edible fruit from the Jurassic of China

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China Geology 2020年第1期3卷 8-15页

作者： Li-jun Chen Ye-mao Hou peng-fei yin Xin Wang Shenzhen Key Laboratory for Orchid Conservation and Utilization National Orchid Conservation Center of China and Orchid Conservation&Research Center of ShenzhenShenzhen 518114China Key Laboratory of Vertebrate Evolution and Human Origin of Chinese Academy of Sciences Institute of Vertebrate Paleontology and Paleoanthropology and Center for Excellence in Life and PaleoenvironmentChinese Academy of SciencesBeijing 100044China State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and Palaeontology and Center for Excellence in Life and PaleoenvironmentChinese Academy of SciencesNanjing 210008China Department of Geology Northwest UniversityXi'an 710069China

Frugivory is an important ecological tie between animals and *** plays an important role in the evolution of food webs and energy flow networks in the ***,little is known about how old this relationship can be due to lack of relevant fossil ***,the authors report a fossil fruit,Jurafructus ***.,a putative angiosperm from the Middle-Late Jurassic(>164 Ma)of Daohugou Village,Inner Mongolia,China,which provides the currently earliest evidence of *** fossil is a more or less three-dimensionally preserved coalified drupe that has been damaged by animals in two different *** pericarp,in addition to the seed coat surrounding parenchyma seed contents,is suggestive of an angiospermous affinity,as such a 3+3 structure is distinct from a three-layered seed coat in *** seed possesses a distal micropyle,attached on the base of the pericarp,suggestive of a former orthotropous ovule in the *** damaged pericarp of Jurafructus suggests that firugivory can be dated back to the Middle-Late ***,the ecological relationship between angiosperms and animals extends deep into the fossil record.

关键词： Jurafructus Jurassic Angiosperm Evolution Animals Frugivory Fruit China

The Future Challenges of Population Health in China:A Projection of the Major Health Problems and Life Expectancy——China,2015-2050

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China CDC weekly 2022年第13期4卷 276-279页

作者： Jiangmei Liu Bo Jiang Yanhong Fu Zhuo Wang Min Liu peng yin Maigeng Zhou National Center for Chronic and Non-Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Department of Epidemiology and Health Statistics Xiangya School of Public HealthCentral South UniversityChangshaChina Department of Chronic and Non-communicable Disease Control and Prevention Sichuan Center of Disease Control and PreventionChengduChina

According to the Seventh National Population Census in 2020,the life expectancy of the Chinese population has been gradually rising in the past 10 years(1).With China’s industrialization,urbanization,and rapidly aging population,behavioral changes,and environmental factors have a growing impact on *** strategy based on“curing disease”cannot meet the public’s health needs.

关键词： Population Challenges Health

Early Warning Analysis of Distributed Internet Financial Risks Based on Big Data

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Early Warning Analysis of Distributed Internet Financial Ris...

Cancer Mortality--China, 2018

作者： peng yin Jinling Institute of Technology

Against the background of national policies supporting Internet innovation, the rapid development of Internet finance requires the establishment of an Internet financial risk warning system for risk prevention. This article starts from big data, according to the characteristics of Internet financial data, follows the data-centric system design principle, divides the system level according to the data processing method, and builds an Internet financial risk early warning system based on big data analysis. By using big data management tools and analysis methods, potential financial risks in Internet finance can be discovered in advance, thereby providing risk management basis for Internet companies, which is conducive to ensuring the healthy and sustainable development of Internet finance companies.

关键词： Big data internet finance financial supervision risk early warning

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China CDC weekly 2020年第5期2卷 63-68页

作者： Yunning Liu Wei Wang Jiangmei Liu peng yin Jinlei Qi Jinling You Lijun Wang Maigeng Zhou National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina.

Introduction Cancer is an important public health concern with heavy disease burden in *** 2017,cancer is the leading cause of death,with around 2.60 million deaths,which accounts for 26.07%of all *** study aims to present cancer mortality in China in 2018 to provide evidence for cancer control and *** Mortality data from China Cause of Death Reporting System(CDRS)and population data from National Bureau of Statistics are used for cancer mortality estimation.A descriptive analysis was conducted to demonstrate the results.

关键词： mortality Cancer cancer

Mortality and Causes of Death in Primary and Secondary School Students--China,2018

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China CDC weekly 2020年第13期2卷 199-204页

作者： Wei Wang Yunning Liu Jiangmei Liu peng yin Jinlei Qi Jinling You Lijun Wang Maigeng Zhou National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?There were approximately 1.23 million deaths reported among individuals aged 5-19 years worldwide in *** attention has been paid to current mortality among primary and secondary school students aged 6-18 years in *** is added by this report?In 2018,an estimated 28,519 deaths occurred among primary and secondary school students aged 6-18 years in China with an age-standardized mortality rate(ASMR)of 17.66 per 100,*** disparities existed among sexes,age groups,areas,and regions for different causes of ***,road traffic injuries,and leukemia were three leading causes of *** are the implications for public health practice?Government support,legislation enforcement,multisectoral cooperation,and stakeholder engagement should be initiated to reduce premature deaths among primary and secondary school students in China,especially those due to injuries.

关键词： injuries initiated deaths

EFFECTS OF TRANSPORT STRESS ON THE INTESTINES INVOLVING NEURONAL NITRIC OXIDE SYNTHASE

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Frontiers of Agricultural Science and Engineering 2023年第2期10卷 285-295页

作者： Jing LAN Tonghui MA peng yin Kedao TENG Yunfei MA College of Veterinary Medicine China Agricultural UniversityBeijing 100193China School of Engineering Medicine Beihang UniversityBeijing 100191China

Transport stress is commonly suffered by animals with gastrointestinal dysfunction a common ***,the mechanisms of transport stress-induced intestine impairment are largely *** aim of this study was to investigate the effects of transport stress on the expression of neuronal nitric oxide synthase(nNOS)and the distribution of nNOS-positive neurons of the intestines in rats and to explore the neuroendocrine mechanism of transport *** this study,Sprague Dawley rats(n=6)were subjected on a constant temperature shaker for 1(S1d)or 3 d(S3d).Rats exhibited increased serum glucose and diminished total number of leukocytes,in which lymphocytes level was also decreased in the S1d group(P<0.05).Also,normal intestinal morphology was disrupted in the S1d rats,and the thickness of muscle layers was decreased in duodenum,jejunum and colon of S3d *** addition,it was found that nNOS expression,as well as the number of nNOSpositive neurons in the myenteric plexus were downregulated in duodenum,jejunum and colon of S3d rats compared with that of unstressed rats(P<0.05).These data reveals that transport stress induced intestinal damage and uncovers potential action mechanisms that nNOS-positive neurons and nNOS expression might be involved in modulating this process.

关键词： intestine nNOS nNOS-positive neurons transport stress

乙型肝炎病毒编码HBsAg区基因突变对免疫检测的影响

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中华检验医学杂志 2005年第7期28卷 687-690页

作者： peng yin 美国雅培制药有限公司上海办事处上海200003

乙型肝炎病毒感染是一个全球性的健康问题,根据美国疾病控制中心的报告[1],全球有将近20亿的感染人群.其中3.5亿人为慢性持续感染。

关键词：乙型肝炎病毒病毒编码 HBsAg 基因突变免疫检测

Trends in the Mortality Rate of Major Kidney Diseases—China,2014–2021

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China CDC weekly 2024年第45期6卷 1171-1176页

作者： Xinhui Yu Jinlei Qi peng yin Limin Wang Yunning Liu Maigeng Zhou Lijun Wang National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Introduction:Kidney disease represents a significant public health issue in China,yet there is a lack of comprehensive knowledge regarding national and regional trends in its mortality and *** study evaluated the mortality,causes,and regional distribution of major kidney diseases in China from 2014 to ***:Data pertaining to kidney disease were obtained from the National Death Cause Surveillance *** were made for both the mortality rates and age-standardized mortality rates(ASMR)for kidney cancer,glomerular disease,tubulointerstitial nephritis,and kidney ***,the average annual percent change(AAPC)was calculated to illustrate trends by sex,urban/rural distinctions,and regional differences from 2014 to ***:There was a significant reduction in the ASMR for all kidney diseases combined from 2014 to *** of age-specific mortality rates reveals a gradual increase beginning at age 35,with a sharp rise after age ***,the ASMR for glomerular disease and kidney failure in females,as well as for tubulointerstitial nephritis in males,displayed a notable ***,the ASMR for glomerular disease in the eastern region and kidney failure in the western region significantly decreased by AAPC of−4.6%and−2.3%,***,the ASMR for kidney cancer in the central region rose significantly(AAPC=2.1%).Conclusion:From 2014 to 2021,the ASMR for major kidney diseases remained high among men,urban residents,and individuals in western *** prevention and control initiatives should prioritize these disparities to mitigate the impact of kidney diseases.

关键词： Kidney mortality prevention

Study on the mechanism of Wuzi-Yanzong-Wan-medicated serum interfering with the mitochondrial permeability transition pore in the GC-2 cell induced by atractyloside

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Chinese Journal of Natural Medicines 2022年第4期20卷 282-289页

作者： WU De-Ling WANG Tong-Sheng LIU Hong-Juan ZHANG Wei TONG Xiao-Hui peng Dai-yin KONG Ling-Yi 无 State Key Laboratory of Natural Medicines Jiangsu Key Laboratory of Bioactive Natural Product ResearchSchool of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 210009China School of Pharmacy Anhui University of Chinese MedicineAnhui Province Key Laboratory of Chinese Medical FormulaHefei 230012China School of Integrated Traditional Chinese and Western Medicine Anhui University of Chinese MedicineHefei 230012China

Wuzi-Yanzong-Wan(WZYZW)is a classic prescription for male *** previous investigation has demon-strated that it can inhibit sperm apoplosis via afecting mitochondria,but the underlying mechanisms are *** purpose of the present study was to explore the actions of WZYZW on mitochondrial permeability transition pore(mPTP)in mouse spermatocyte cell line(GC-2 cells)opened by atractyloside(ATR).At first,WZYZW-mediated serum was prepared from rats following oral adminis-tration of WZYZW for 7 ***-2 cells were divided into control group,model group,positive group,as well as 5%,10%,15%WZYZW-medicated serum *** A(CsA)was used as a positive control.50 μmol·L^(-1) ATR was added afer drugs *** viability was asessed using *** was detected using flow cytometry and TUNEL *** opening of mPTP and mitochondrial membrane potential(MMP)were dected by Calcein AM and JC-1 fuorescent probe *** mRNA and protein levels of voltage-dependent anion channel I(VDACI),cyelophilin D(CypD),adenine nucleide translocator(ANT),cytochrome C(Cyt C),caspase 3,9 were dected by RT-PCR(real time quantity PCR)and Western blotting *** results demonstrated that mPTP of GC-2 cells was opened alpter 24 hours of ATR treatment,resulting in decreased MMP and increased ***-protection with WZYZ-medicated serum and CsA inhibited the opening of mPTP of GC-2 cells induced by ATR associ ated with increased MMP and decreased ***,the results of RT-qPCR and WB suggested that WZYZW-medicated serum could significantly reduce the mRNA and protein levels of VDACI and CypD,Caspase-3,9 and CylC,as well as a increased ra-tio of ***,ANT was not significantly ***,these findings indicated that WZYZW inhibited mitochondri-al mediated apoptosis by atenuating the opening of mPTP in GC-2 ***-medicated serum inhibited the expressions of VDACI and CypD and increased the expression of Bcl-2

关键词： Wuzi-Yanzong-Wan Mitochondrial permeability transition pore Voltage-dependent anion channel 1 Cyclophilin D Mitochondrial membrane potential