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Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics

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Virologica Sinica 2017年第6期32卷 548-552页

作者： peng bi Bo Shu peng Gong Key Laboratory of Special Pathogens and biosafety Wuhan Institute of VirologyChinese Academy of SciencesWuhan 430071China University of Chinese Academy of Sciences Beijing lOO049China

Dear Editor, Coxsackievirus A16 （CV A16） and enterovirus 71 （EV71） are currently the two primary causative agents of hand- foot-and-mouth disease （HFMD）（Solomon et al., 2010; Mao et al., 2014）, threatening health of children world- wide. They both belong to the Enterovirus genus of the Picornaviridae family, and have single-stranded positive- sense RNA genomes of about 7.5 kilobases （kb） in length. As with other positive-strand RNA viruses, the genome rep- lication process ofCV A16 is carried out by a membrane- associated replication complex with the virally encoded RNA-dependent RNA polymerase （RdRP） as the essential catalytic enzyme.

关键词： Crystal structure A16 RNA-dependent RNA polymerase

Research on low carbon emission optimization operation technology of natural gas pipeline under multi-energy structure

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Petroleum Science 2022年第6期19卷 3046-3058页

作者： En-bin Liu Yong peng Shan-bi peng bin Yu Qi-Kun Chen Petroleum Engineering School Southwest Petroleum UniversityChengdu610500China School of Civil Engineering and Geomatics Southwest Petroleum UniversityChengdu610500China China Petroleum Pipeline Engineering Corporation Hebei065000China School of Engineering Cardiff UniversityCardiffCF243AAUK

In order to reduce the carbon emissions of natural gas pipelines,based on the background of different energy structures,this paper proposes a general low carbon and low consumption operation model of natural gas pipelines,which is used to fine calculate the carbon emissions and energy consumption of natural gas *** this paper,an improved particle swarm optimization(NHPSO-JTVAC)algorithm is used to solve the model and the optimal scheduling scheme is *** a parallel pipeline located in western China as an example,the case is *** results show that after optimization,under the existing energy types,the pipeline system can reduce 31.14%of carbon emissions,and after introducing part of new energy,the pipeline system can reduce 34.02%of carbon emissions,but the energy consumption has increased.

关键词： Natural gas Pipeline optimization NHPSO-JTVAC algorithm Carbon emission New energy

Climate change and population health research in China: Knowledge gaps and further directions

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Advances in Climate Change Research 2020年第3期11卷 273-278页

作者： peng bi SHI Xiao-Ming LIU Qi-Yong School of Public Health The University of AdelaideAdelaideSA 5000Australia National Institute of Environmental Health Chinese Center for Disease Control and PreventionBeijing 102206China National Institute of Infectious Diseases Chinese Center for Disease Control and PreventionBeijing 102206China

Climate change and its impact on population health have been well explored in China in recent years,especially health risk assessments such as studying its impact on the transmission and development of climate-sensitive infectious diseases and non-communicable ***,knowledge gaps including using morbidity as health indicators(***,ED visits,and ambulance call-outs),identifying disease attributable contributions to climate variability and burden of diseases due to climate change,calculating related healthcare costs,and developing climate change adaptation and mitigation strategies need to be *** research directions could focus on both mitigation and health adaptation studies,such as exploring active transportation and green hospitals,studying health co-benefits,identifying vulnerable populations,prioritizing resource allocation,building healthcare capacity and capability,evaluating intervention effect,developing tailored risk communication strategies and community health education packages for vulnerable communities in the context of climate change.

关键词： Climate change Population health China Future direction

Joint-state differential detection algorithm and its application in UWB wireless communication systems

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Science in China(Series F) 2007年第6期50卷 897-904页

作者： ZHANG peng bi GuangGuo CAO XiuYing National Mobile Communication Research Laboratory Southeast University Nanjing 210096 China

In this paper, a novel concept of the joint state of input and output of encoder is proposed. Based on it, a recursive algorithm that implements the multi-symbol differential detection in criterion of maximum likelihood is proposed. Simulation results show that its performance can approach to the theoretical boundary of multi-symbol differential detection without increasing the complexity per symbol, and it is effective in practical systems. It is also an optimal algorithm to solve the problems of estimating the state sequence of finite-state Markov process observed in memoryless noise.

关键词： differential detection maximum likelihood joint state iteration

Chemical inequivalence behavior of the protons attached to the same carbon in ethylene-propylene copolymer(EPC)

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Chinese Chemical Letters 2008年第4期19卷 469-474页

作者： peng Yu bi Hui Ru Dong Nan Nan Wang College of Science Beijing University of Chemical TechnologyBeijing 100029PR China

Six ethylene-propylene copolymer samples with different structural parameters were analyzed by ^1H NMR,^13C NMR and ^1H-^13C COSY in this *** the aid of the ^1H-^13C COSY spectra of ethylene-propylene copolymer,the chemical inequivalence behavior of the protons attached to the same carbon in the ethylene-propylene copolymer could be observed. Four basic types of chemical bonds were divided,and two kinds of main conformations were proposed to explain this phenomenon. Based on the calculation of conformation distribution,it can be proved that the explanation of this phenomenon was reasonable.

关键词： Chemical inequivalence Ethylene-propylcne copolymer NMR

Effect of water droplet in solvent sublation

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Chinese Chemical Letters 2008年第5期19卷 623-626页

作者： peng Yu bi Hui Ru Dong Nan Nan Wang College of Science Beijing University of Chemical Technology Beijing 100029 China

Aqueous phase layer around bubble and water droplet are two additional processes in solvent sublation. In the dynamic process of mass transfer, they are always neglected, but they are very important in the investigation of thermodynamic equilibrium. In this paper, the effect of water droplet in solvent sublation was discussed in detail, and the previous mathematical model of solvent subaltion was improved. Matlab 6.5 was used to simulate the process of water droplets, and the comparison between the previous hypothesis and the improvement in this paper showed the superiority, especially in the investigation of thermodynamic equilibrium. Moreover, the separation and concentration of the complex compound dithizone-Co（Ⅱ） from aqueous phase to n-octanol by solvent sublation also proved the improved mathematical model was reasonable.

关键词： Solvent sublation Water droplet Mathematical model

Critical bubble radius in solvent sublation

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Chinese Chemical Letters 2007年第10期18卷 1293-1296页

作者： peng Yu bi Hui Ru Dong Nan Nan Wang College of Science Beijing University of Chemical Technology Beijing 100029 People＇s Republic of China

The complex compound of dithizone-Co（Ⅱ） was separated and concentrated from the aqueous phase to n-octanol by solvent sublation. From the analysis of the coalescence behavior of bubbles on water-organic interface, the conception of critical bubble radius was proposed, and the value of the critical bubble radius in the water-octanol system was obtained： 1.196 × 10^-3 m. The simulation of the mathematical model using CBR and experimental data is completed with perfect results, and the simulation of the mathematical model using CBR is very different with the classic one. The analytical results proved that the critical bubble radius should be adequately considered in mathematical model of solvent sublation.

关键词： Solvent sublation Coalescence behavior Bubble Critical bubble radius

Polymer electrolyte with composite cathode for solid-state Li–CO_2 battery

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Rare Metals 2018年第6期37卷 520-526页

作者： Muhammad Mushtaq Xian-Wei Guo Jie-peng bi Zhao-Xiang Wang Hai-Jun Yu College of Materials Sciences and Engineering Beijing University of Technology Key Laboratory for Renewable Energy Chinese Academy of Sciences Beijing Key Laboratory for New Energy Materials and Devices Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences School of Physical Sciences University of Chinese Academy of Sciences

The rechargeable Li-CO2 battery has attracted much attention for energy storage because of the high energy density and efficient utilization of greenhouse gas. However, it＇s still suffered by low safety issue of liquid electrolyte. Herein, a composite cathode consisting of CNTs and polymer electrolytes was fabricated by the insitu polymerization process for the polymer electrolyte-based solid-state Li-CO2 batteries. With the good dispersion of CNTs and polymer electrolyte, the composite cathode is covered by film-like discharge products ***, the Li-CO2 battery shows high reversible capacity （- 11,000 mAh·g^-1）, excellent cycle stability （1000 mAb·g^-1 for 100 cycles） under low charge potential （〈 4.5 V）, and outstanding rate performances at room temperature, which are much better than those of liquid electrolyte-based battery. Therefore, the polymer electrolyte-based Li-CO2 battery prepared by this strategy can be a promising candidate to meet the demands of high safety and high-performance energy storage devices.

关键词： Carbon dioxide Li-CO2 batteries Polymerelectrolyte Li2CO3 Battery performances

Health risks from non-optimal temperatures in different populations and regions in China:Tailored intervention strategies are needed

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Advances in Climate Change Research 2023年第3期14卷 416-419页

作者： Yong-Hong LI peng bi Shilu TONG Xiao-Yuan YAO China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijing 100021China School of Public Health University of AdelaideAdelaide 5005Australia School of Public Health and Social Work Queensland University of Technology BrisbaneBrisbane 4006Australia

Identifying temperature-sensitive diseases,vulnerable populations and attributable disease burden is crucial for the development and implementation of tailored climate change adaptation strategies in the context of climate change,especially through both mortality and morbidity analysis by using the data from same regions and *** re-analyzed and outlined the whole picture of the impacts of extreme temperatures on both mortality and morbidity among various populations and regions,based on the researches from a well-planned national project of Scientific Survey of Regional Meteorological Sensitive Diseases(SRMSD)with consistent methodology in *** twenty-four representative regions of the SRMSD project cover all eleven geographical meteorological divisions in the country,including urban and rural *** addition to circulatory and respiratory diseases,we found that neurological diseases,injuries,digestive diseases,endocrine diseases,genitourinary diseases,skin and subcutaneous tissue diseases were sensitive to extreme heat,while digestive diseases were sensitive to extreme *** extreme temperature-sensitive diseases and the attributable disease burden varied by *** and the elderly people(65 years old and above)were more vulnerable to extreme heat when using mortality as a health outcome,whereas males and the young and middle-aged adults were more vulnerable to morbidity risk from *** findings provide important scientific evidence for regional distribution of temperature-sensitive diseases and identification of vulnerable populations in *** provides evidence and implications of developing regional heat/cold-exposure intervention policies,especially for hospital emergency departments and ambulance services during hot seasons.

关键词： Climate change Temperature Sensitive disease Vulnerable population Tailored intervention