检索结果-南通市图书馆

Oncological outcome of unresectable lung metastases without extrapulmonary metastases in colorectal cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第26期16卷 3318-3324页

作者： Li, Wen-Hua peng, jun-jie Xiang, Jia-Qing Chen, Wei Cai, San-jun Zhang, Wen Fudan Univ Shanghai Canc Ctr Dept Med Oncol Shanghai 200032 Peoples R China Fudan Univ Shanghai Canc Ctr Dept Colorectal Surg Shanghai 200032 Peoples R China Fudan Univ Shanghai Canc Ctr Dept Thorac Surg Shanghai 200032 Peoples R China Univ Michigan Dept Biostat Ann Arbor MI 48710 USA

AIM: To explore the oncological outcomes of unresectable lung metastases without extrapulmonary metastases in colorectal cancer. METHODS: Patients with unresectable isolated lung metastases from colorectal cancer were prospectively collected in a single institution during a 5-year period. All patients received either the fluorouracil/leucovorin plus oxaliplatin, fluorouracil/leucovorin plus irinotecan or capecitabine plus oxaliplatin regimen as first-line treatment. The resectability after preoperative chemotherapy was evaluated. Patients' outcome and predictive factors for overall survival were also investigated by univariate and multivariate ***: A total of 70 patients were included in the study. After standardized fi rst-line chemotherapy, only 4 patients (5.7%) were converted to resectable disease. The median overall survival time in all patients was 19 mo (95% CI: 12.6-25.4), with a 2-year overall survival rate of 38.8%. No survival difference was found among different fi rst-line chemotherapeutic regimens. Prognostic analysis demonstrated that only the fi rst response assessment for fi rst-line treatment was the independent factor for predicting overall survival. The median survival time in partial response, stable disease and progressive disease patients were 27 mo, 16 mo and 8 mo (P = 0.00001). CONCLUSION: Pulmonary metastasectomy can only be performed in a small part of unresectable lung metastases patients after chemotherapy. Patients' first response assessment is an important prognostic factor.

关键词： Colorectal cancer Lung Metastases Chemotherapy

Construction of chimeric viruses based on pepper mild mottle virus using a modiffed Cre/loxP system

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2022年第8期21卷 2456-2463页

作者： YIN Yue-yan HUA Meng-ying ZHAO Kuang-jie WAN Qiong-lian BU Shan LU Yu-wen ZHENG Hong-ying RAO Shao-fei YAN Fei peng jie-jun CHEN Hai-ru CHEN Jian-ping College of Plant Protection Yunnan Agricultural UniversityKunming 650201P.R.China Institute of Alpine Economic Plants Yunnan Academy of Agricultural SciencesLijiang 674100P.R.China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agroproducts Institute of Plant VirologyNingbo UniversityNingbo 315211P.R.China Longping Branch of Graduate College Hunan UniversityChangsha 410125P.R.China

Cre/loxP,a site-specific recombination system,has been widely used for various purposes,including chromosomal translocations,generation of marker-free transgenic plants,tissue-specific activation of a reporter gene and efficient heterologous gene expression in ***,stable or transient expression of Cre recombinase in plants can cause chlorosis or ***,we describe a modified Cre/loxP recombination system using a DNA fragment flanked with loxP sites in the same orientation in which necrosis induced by Cre recombinase in Nicotiana benthamiana leaves was *** modified system was successfully used to create functional GFP-tagged pepper mild mottle virus(PMMoV)and a chimeric virus with coat protein(CP)substitution assembled from separate pro-vector *** results provide a new strategy and flexible technique to construct chimeric virus and infectious clones for plant viruses with large genomes.

关键词： pepper mild mottle virus Cre/loxP necrosis infectious cDNA clone chimeric virus

在线全文

学校读者我要写书评

暂无评论

基于方面级情感分析的深度语义挖掘模型

电子学报 2024年第7期52卷 2307-2319页

作者：张换香彭俊杰上海大学计算机工程与科学学院上海200444 上海先进通信与数据科学研究院上海200444 内蒙古科技大学创新创业教育学院内蒙古包头014010

方面级情感分析是一种细粒度的情感分类任务,具有广泛的应用前景,正因为如此,得到了广泛关注与研究,尤其是近年来,基于依赖树的图神经网络和基于注意力的网络模型的研究取得了较大进展.但是,由于在线评论表达的复杂性和依赖关系不易解... 详细信息

方面级情感分析是一种细粒度的情感分类任务,具有广泛的应用前景,正因为如此,得到了广泛关注与研究,尤其是近年来,基于依赖树的图神经网络和基于注意力的网络模型的研究取得了较大进展.但是,由于在线评论表达的复杂性和依赖关系不易解析使得这些方法在情感分析的性能上得不到有效提升.为了克服这些挑战,本文提出了一种同时考虑句法语义和上下文语义的深度语义挖掘模型(Deep Semantic Mining Model,DSMM).具体地,为了深度挖掘句法背后隐含的深度语义,模型采用并行的图卷积和多头注意力机制挖掘丰富的语义;为了充分利用句法语义和上下文语义的内在关联关系,采用了关联注意力机制获取句法语义和上下文语义的相关性,并且采用自适应方面路由机制有效获取方面的情感语义,并在此基础上,通过引入基于依赖树的语义位置嵌入,进一步增强方面-意见词的关联.在三个公共数据集上的实验结果表明,该模型在复杂句情感分析中既能从不同语义空间挖掘句子的语义特征,也能有效利用句法特征强化句子的语义表征,在分类准确率和泛化能力上的表现优于相关工作.

关键词：方面级情感分析图卷积神经网络多头注意力机制关联注意力句法上下文语义

Modeling of goethite iron precipitation process based on time-delay fuzzy gray cognitive network

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2019年第1期26卷 63-74页

作者： CHEN Ning ZHOU Jia-qi peng jun-jie GUI Wei-hua DAI Jia-yang School of Information Science and Engineering Central South University

The goethite iron precipitation process consists of several continuous reactors and involves a series of complex chemical reactions,such as oxidation reaction,hydrolysis reaction and neutralization *** is hard to accurately establish a mathematical model of the process featured by strong nonlinearity,uncertainty and time-delay.A modeling method based on time-delay fuzzy gray cognitive network(T-FGCN)for the goethite iron precipitation process was proposed in this *** the basis of the process mechanism,experts’practical experience and historical data,the T-FGCN model of the goethite iron precipitation system was established and the weights were studied by using the nonlinear hebbian learning(NHL)algorithm with terminal *** analyzing the system in uncertain environment of varying degrees,in the environment of high uncertainty,the T-FGCN can accurately simulate industrial systems with large time-delay and uncertainty and the simulated system can converge to steady state with zero gray scale or a small one.

关键词： time-delay fuzzy gray cognitive network(T-FGCN) iron precipitation process nonlinear Hebbian learning

云存储中一种基于布局的虚拟磁盘节能调度方法

在线全文

学校读者我要写书评

暂无评论

电子学报 2012年第11期40卷 2247-2254页

作者：李建敦彭俊杰张武上海大学计算机工程与科学学院上海200072 上海电机学院电子信息学院上海201306 上海大学高性能计算中心上海200072

在云存储中,如何有效地调度用户请求到目标磁盘以实现绿色节能存储是一个热点问题.鉴于云存储对节能调度算法提出的新要求,如请求响应时间敏感与对动态优化的限制等,本文提出了一种基于布局的虚拟磁盘节能调度方法.该方法将磁盘阵列动... 详细信息

在云存储中,如何有效地调度用户请求到目标磁盘以实现绿色节能存储是一个热点问题.鉴于云存储对节能调度算法提出的新要求,如请求响应时间敏感与对动态优化的限制等,本文提出了一种基于布局的虚拟磁盘节能调度方法.该方法将磁盘阵列动态划分为工作区与就绪区,以工作区为主向用户分发资源,并以未连接虚拟机的虚拟磁盘为单位,根据实时负载情况对虚拟磁盘布局进行动态优化.实验结果表明,这种方法不仅能够降低磁盘阵列的能耗,而且能够有效地缓解响应时间延长的问题,还能够使虚拟磁盘布局达到更高的负载均衡水平.

关键词：云计算云存储虚拟磁盘节能调度负载均衡

在线全文

学校读者我要写书评

暂无评论

基于全景信息的环网柜智能控制系统

华东电力 2014年第11期42卷 2476-2479页

作者：彭俊杰广东电网公司佛山顺德供电局广东佛山528300

针对当前电力系统中压配电网信息分散和信息孤岛问题,以开关在线监测与故障诊断技术为基础,结合继电保护和测控技术,提出基于全景信息的智能配网开关系统。在研究环网柜智能控制系统方案和结构基础上,重点介绍了配电终端等关键技术。环... 详细信息

针对当前电力系统中压配电网信息分散和信息孤岛问题,以开关在线监测与故障诊断技术为基础,结合继电保护和测控技术,提出基于全景信息的智能配网开关系统。在研究环网柜智能控制系统方案和结构基础上,重点介绍了配电终端等关键技术。环网柜智能控制系统在某供电局的现场应用验证了其先进性。

关键词：配电网全景信息智能控制系统自诊断

Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 317-326页

作者： Binglu Deng jie Shen Jinxing Lu Chuqiang Huang Zhuoyuan Chen Feng peng Yunpeng Liu School of Materials Science and Hydrogen Energy Foshan University School of Chemistry and Chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （ClOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-CoP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-CoP2to Ru-CoOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-CoP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Glycerol electrooxidation Hydrogen evolution Ru doping Cobalt phosphide Bifunctional electrocatalysts

基于模糊认知网络的改进非线性Hebbian算法

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

控制理论与应用 2016年第10期33卷 1273-1280页

作者：陈宁王磊彭俊洁刘波桂卫华中南大学信息科学与工程学院湖南长沙410083

针对难以用机理模型准确描述的非线性系统,研究基于模糊认知网络(fuzzy cognitive networks,FCN)的非线性系统建模和参数辨识问题.首先,建立非线性系统的具有数值推理和模糊信息表达的模糊认知网络模型,利用包含节点、权值和反馈的有向... 详细信息

针对难以用机理模型准确描述的非线性系统,研究基于模糊认知网络(fuzzy cognitive networks,FCN)的非线性系统建模和参数辨识问题.首先,建立非线性系统的具有数值推理和模糊信息表达的模糊认知网络模型,利用包含节点、权值和反馈的有向图表示系统.其次,由于模型的精确性取决于权值参数,提出了一种带终端约束的非线性Hebbian学习算法(nonlinear Hebbian learning,NHL).该算法在权值的学习过程中引入了FCN模型中节点的系统实际值,在原更新机制的基础上,增加了包含反馈值与预测值差值的修正项,然后归一化得到最终权值迭代公式.该算法具有收敛速度快、学习结果精准等优点,解决了传统非线性Hebbian算法对初始值依赖性强的缺点.最后将所提出的方法运用到水箱控制系统,仿真结果说明了基于FCN的非线性Hebbian学习算法的有效性.

关键词：模糊认知网络非线性Hebbian学习算法终端约束

在线全文

学校读者我要写书评

暂无评论

基于改进BoS的Web文本分类研究

南京邮电大学学报（自然科学版） 2013年第1期33卷 79-83页

作者：彭俊杰陈丹敏河南大学计算机与信息工程学院河南开封475004

提出了改进的文本相似度计算方法,在计算文本的相似度时,赋予不同文本块中的句子不同的权值,同时直接去掉短句子和合并高相似度的句子以精简句子包中句子数量以提高运算速度。改进后的文本相似度计算方法为:先根据句子相似度的计算方法... 详细信息

提出了改进的文本相似度计算方法,在计算文本的相似度时,赋予不同文本块中的句子不同的权值,同时直接去掉短句子和合并高相似度的句子以精简句子包中句子数量以提高运算速度。改进后的文本相似度计算方法为:先根据句子相似度的计算方法计算句子的相似度,再计算文本块的相似度,最后按照文本块的权值计算整个文本的相似度。经试验证明,改进后的算法在文本召回率、准确率和F1值上都有明显的提高。

关键词： Web文本分类句子包向量空间模型文本挖掘