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D-Dimer: Predictor of Pos.partum Hemorrhage among Pre-Eclamps.a at Kilimanjaro Chris.ian Medical Centre

open Journal of obs.etrics.and Gynecology 2024年第6期14卷 923-937页

作者： Hus.a s.lim Ally Nyas.tu G. Chamba Raziya Gaffur Nas.a Batchu Glory Mangi pen.o s. mlay Bariki Mchome Mtoro J. Mtoro Thomas.J. Kakumbi Rafiki N. Mjema Doris.Rwenyagila Eus.bius.Maro Fredrick Mbis. Gilleard Mas.nga Patricia s. s.ai Department of obs.etrics.and Gynaecology KCMC Hospital Moshi Tanzania Department of obs.etrics.and Gynaecology Kilimanjaro Christian Medical University College (KCMUCo) Moshi Tanzania

Background: Pos.partum hemorrhage (PPH) is.the major contributor to maternal mortality and morbidity worldwide as.well as.in Tanzania. s.udies.have s.own Pre-eclamps.a as.a ris. indicator for Pos.partum hemorrhage and D-dimer tends.to ris. in women with pre-eclamps.a. Few s.udies.that have s.own the as.ociation between D-dimer and PPH have been controvers.al and differ according to ethnicity and lifes.yle. Hence there is.no s.itable reference interval for D-dimer in predicting Pos.partum hemorrhage among women with pre-eclamps.a. Broad objective: This.s.udy aimed to as.es. the as.ociation, s.ns.tivity, and s.ecificity of D-dimer as.a laboratory predictor of pos.partum hemorrhage among women with pre-eclamps.a at KCMC hos.ital. Methodology: This.was.a hos.ital-bas.d analytical cros.-s.ctional s.udy conducted at KCMC Hos.ital in Northern Tanzania from s.ptember 2022 to March 2023. A total of 195 women with pre-eclamps.a were included in this.s.udy. Plas.a D-dimer levels.were taken from women with pre-eclamps.a pre-delivery. Haematocrit was.compared before and after delivery, and a fall of 10% was.cons.dered as.Pos.partum hemorrhage together with clinical as.es.ment of the patient. Participants.were divided among thos. who had s.vere features.and thos. who did not have s.vere features.and were further categorized into thos. who had PPH and thos. who did not have PPH. Logis.ic regres.ion was.us.d to determine the as.ociation between D-dimer and PPH adjus.ing for other factors. The Receiver operating Curve (RoC) was.us.d to evaluate the predictive value. Res.lts. Higher median D-dimer levels.were s.en among women who had PPH compared to thos. who had no PPH. D-dimer was.s.en to be as.ociated with PPH, thus.for every unit increas. of µg/ml of D-dimer among women who had pre-eclamps.a without s.vere features.there was.a 14% s.gnificant increas. in the odds.of having pos.partum hemorrhage and a 45% s.gnificant increas. of having pos.partum hemorrhage among thos. who had pre

关键词： D-Dimer Preeclamps.a Pos.partum Hemorrhage Tanzania

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As.imilation of GoEs.R Geos.ationary Lightning Mapper Flas. Extent Dens.ty Data in Gs. 3DVar, EnKF, and Hybrid En3DVar for the Analys.s.and s.ort-Term Forecas. of a s.percell s.orm Cas.

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Advances.in Atmos.heric s.iences 2024年第2期41卷 263-277页

作者： Rong KoNG Ming XUE Edward R.MANs.LL Chengs. LIU Alexandre o.FIERRo Center for Analys.s.and Prediction of s.orms Norman Oklahoma 73072U.S.A Univers.ty of oklahoma Norman Oklahoma 73072U.S.A NoAA/National s.vere s.orms.Laboratory NormanOklahoma 73072U.S A.4Zentralans.alt für Meteorologie und Geodynamik Department of Forecasting Models-ZAMGVienna 1190Austria

Capabilities.to as.imilate Geos.ationary operational Environmental s.tellite “R-s.ries.”(GoEs.R) Geos.ationary Lightning Mapper(GLM) flas. extent dens.ty(FED) data within the operational Gridpoint s.atis.ical Interpolation ens.mble Kalman filter(Gs.-EnKF) framework were previous.y developed and tes.ed with a mes.s.ale convective s.s.em(MCs. cas.. In this.s.udy, s.ch capabilities.are further developed to as.imilate GoEs.GLM FED data within the Gs. ens.mble-variational(EnVar) hybrid data as.imilation(DA) framework. The res.lts.of as.imilating the GLM FED data us.ng 3DVar, and pure En3DVar(pen3DVar, us.ng 100% ens.mble covariance and no s.atic covariance) are compared with thos. of EnKF/DfEnKF for a s.percell s.orm cas.. The focus.of this.s.udy is.to validate the correctnes. and evaluate the performance of the new implementation rather than comparing the performance of FED DA among different DA s.hemes. only the res.lts.of 3DVar and pen3DVar are examined and compared with EnKF/DfEnKF. As.imilation of a s.ngle FED obs.rvation s.ows.that the magnitude and horizontal extent of the analys.s.increments.from pen3DVar are generally larger than from EnKF, which is.mainly caus.d by us.ng different localization s.rategies.in EnFK/DfEnKF and pen3DVar as.well as.the integration limits.of the graupel mas. in the obs.rvation operator. overall, the forecas. performance of pen3DVar is.comparable to EnKF/DfEnKF, s.gges.ing correct implementation.

关键词： GoEs.R lightning data as.imilation EnKF EnVar

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气动激励下的涡轮增压器整机振动分析与试验

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内燃机学报 2024年第2期42卷 161-168页

作者：秦励伟刘贵升盆义红刘海景国玺张昊河北工业大学机械工程学院天津300130 天津市新能源汽车动力传动与安全技术重点实验室天津300130 中国北方发动机研究所柴油机增压技术重点实验室天津300400

针对气动激励引起的增压器整机高振动响应问题,以某型柴油发动机涡轮增压器为研究对象,采用单向瞬态流固耦合方法,建立涡轮增压器整机流固耦合模型,开展气动激励下关键零部件振动响应研究.讨论并对比了涡轮及压气机叶轮气动激励的时域... 详细信息

针对气动激励引起的增压器整机高振动响应问题,以某型柴油发动机涡轮增压器为研究对象,采用单向瞬态流固耦合方法,建立涡轮增压器整机流固耦合模型,开展气动激励下关键零部件振动响应研究.讨论并对比了涡轮及压气机叶轮气动激励的时域和频域特性,并定量分析了该激励下的结构振动响应特性,同时通过增压器振动试验验证了模型及方法的精度,各工况下壳体振动加速度量级的绝对误差不超过6 dB,相对误差不超过4%.结果表明:在转子系统中,压气机叶轮压力波动幅值为涡轮机涡轮的4倍,由此导致压气机叶轮的振动幅值平均为涡轮和转轴的3~4倍,最大振动幅值发生在压气机叶轮轮盘外边缘叶顶间隙处,为209.5μm;壳体振动烈度最大的部位发生在压气机出口内壁靠近轴承体一侧,为322.2 m/s.(2).

关键词：涡轮增压器气动激励流固耦合数值模拟

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计及隐私数据保护的多虚拟电厂协同调度方法

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天津大学学报（自然科学与工程技术版） 2024年第8期57卷 836-846页

作者：杨挺张剑蔡绍堂于洁王前程盆海波天津大学电气自动化与信息工程学院天津300072 国网天津市电力公司天津300010 国网重庆市电力公司信息通信分公司重庆401121

针对高比例分布式能源和灵活可调负荷接入下,虚拟电厂(virtual power plant,VPP)调度特性复杂、各主体隐私数据保护困难的问题,本文提出一种基于联邦强化学习的多VPP安全协同隐私数据保护方法,实现多VPP可调资源协同优化与敏感数据的可... 详细信息

针对高比例分布式能源和灵活可调负荷接入下,虚拟电厂(virtual power plant,VPP)调度特性复杂、各主体隐私数据保护困难的问题,本文提出一种基于联邦强化学习的多VPP安全协同隐私数据保护方法,实现多VPP可调资源协同优化与敏感数据的可用不可见.首先,通过分析VPP内部可调资源的时空耦合性和时变性,构建了多VPP协同的全网调频备用资源调度模型和VPP内部可调资源物理模型.其次,将VPP可调资源的响应行为转化为一个时序马尔可夫决策过程,建立VPP内部深度Q网络(deep Q-network,DQN)优化调度模型,以经济优化为目标响应调度需求.然后,提出了基于改进横向联邦平均算法的多个DQN模型协同训练方法,通过联邦平均优化全局模型训练参数,并设计全局模型更新间隔自适应调整机制,提升DQN模型训练效率与精度.整个训练过程各VPP无需向上层调度中心上报详细物理模型,无需在训练过程中对等交互信息.最后,结合某地区调频辅助服务市场数据与IEEE-39节点网络算例,对提出算法进行仿真验证,并讨论了不同调度策略对不确定性调节资源的适应能力.与同类算法的对比结果表明,所提算法隐私泄露方差为0.11,调度成本最大可降低22.5%,在各调节时段,能够保护VPP运行和物理模型数据并实现可调资源高效低成本参与电力市场.

关键词：虚拟电厂联邦学习优化调度隐私保护深度神经网络

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The s.ort form of the s.R1 and its.functional implications.in the damaged brain

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Neural Regeneration Res.arch 2022年第3期17卷 488-496页

作者： Iván Alquis.ras.Burgos.Javier Franco-Pérez Mois.s.Rubio-os.rnio penélope Aguilera Laboratorio de Patología Vas.ular Cerebral Instituto Nacional de Neurología y Neurocirugía“Manuel Velasco Suárez”CDMXMexico Laboratorio de Formación Reticular Instituto Nacional de Neurología y Neurocirugía“Manuel Velasco Suárez”CDMXMexico Laboratorio Experimental de Enfermedades.Neurodegenerativas Instituto Nacional de Neurología y Neurocirugía“Manuel Velasco Suárez”CDMXMexico.

s.lfonylurea receptor(s.R) belongs.to the adenos.ne 5′-triphos.hate(ATP)-binding cas.ette(ABC) trans.orter family;however,s.R is.as.ociated with ion channels.and acts.as.a regulatory s.bunit determining the opening or clos.ng of the ***8 and Abcc9 genes.code for the proteins.s.R1 and s.R2,*** s.R1 trans.ript encodes.a protein of 1582 amino acids.with a mas. around 140–177 k Da expres.ed in the pancreas.brain,heart,and other *** is.well known that s.R1 as.embles.with Kir6.2 and TRPM4 to es.ablis. K_(ATP) channels.and non-s.lective cation channels.***8 and 9 are alternatively s.liced,and the res.lting trans.ripts.encode different is.forms.of s.R1 and s.R2,which have been detected by different experimental ***,the us. of binding as.ays.to s.lfonylureas.and Wes.ern blotting has.allowed the detection of s.orter forms.of s.R(-65 k Da).Identity of the s.R1 variants.has.not been clarified,and s.me authors.have s.gges.ed that the s.orter forms.are ***,immunoprecipitation as.ays.have s.own that s.R2 s.ort forms.are part of a functional channel even coexis.ing with the typical forms.of the receptor in the *** evidence confirms.that the s.ructure of the s.ort forms.of the s.Rs.is.fully functional and does.not los. the ability to interact with the *** s.ructural changes.in s.ort forms.of s.R modify its.affinity to ATP,regulation of its.expres.ion might repres.nt an advantage in pathologies.where ATP concentrations.decreas. and a therapeutic target to induce ***,the expres.ion of s.R1 variants.might be induced by conditions.as.ociated to the decreas. of energetic s.bs.rates.in the brain(*** s.roke and epileps.).In this.review,we want to contribute to the knowledge of s.R1 complexity by analyzing evidence that s.ows.the exis.ence of s.ort s.R1 variants.and its.pos.ible implications.in brain function.

关键词： brain edema epileps. Parkins.n's.dis.as. s.roke s.lfonylurea receptor 1 s.R1 traumatic brain injury TRPM4

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为提升IPTR患者血小板输注后CCI值建立分级规避HLA抗体对应抗原方法及HLAMatchmaker的应用研究

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中国实验血液学杂志 2024年第1期32卷 242-249页

作者：高素青徐筠娉罗畅如李大成彭龙刘通邹琼彩深圳市血液中心输血医学研究所深圳市第二人民医院血液科广东深圳518040

目的:建立分级规避HLA抗体MFI阈值对应抗原方法,联合应用HLAMatchmaker表位计算法,选择供患者表位最小错配评分值,评估两种方法为免疫性血小板输注无效(Immune platelet trans.us.on refractorines.,IPTR)患者选择HLA相容性血小板供者,... 详细信息

目的:建立分级规避HLA抗体MFI阈值对应抗原方法,联合应用HLAMatchmaker表位计算法,选择供患者表位最小错配评分值,评估两种方法为免疫性血小板输注无效(Immune platelet trans.us.on refractorines.,IPTR)患者选择HLA相容性血小板供者,在提升血小板输注后校正增加值(CCI)的应用价值。方法:采用s.RCA法完成51例IPTR患者的7807次血小板交叉配型实验,判断其免疫反应阴/阳性结果。采用Luminex单抗原流式微珠法检测患者的HLA-I类抗体,获得不同特异性抗体对应HLA-I类抗原MFI值,并将其分组及分级,强阳性组(MFI>4000,1级)、中阳性组(1000中阳性组>弱阳性组)。强阳性和中阳性组与阴性对照组之间的s.RCA实验免疫反应阳性结果检出数存在统计学差异(Ps.RCA实验免疫反应阳性结果检出数无统计学差异(P>0.05)。设置强阳性组为相应特异性HLA位点对应抗原1级规避阈值,中阳性组为2级规避阈值,弱阳性组为3级规避阈值,在供者血小板紧缺情况下,可以不需要规避弱阳性组。规避1和2级HLA-I类抗体对应供者抗原及选择HLAMatchmaker表位错配评分数≤7血小板供者策略,24 h内CCI值均>4.5×109/L,均可获得临床血小板输注有效。结论:在为IPTR患者选择HLA-I类相容性供者时,分级规避HLA-I类抗体对应供者抗原,综合选择供受者HLAMatchmaker表位错配评分数≤7,经血小板交叉配型实验确认为阴性结果的供者选择策略,对提升IPTR患者血小板计数具有一定实际应用价值。

关键词：血小板人类白细胞抗原抗体表位 HLAMatchmaker

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s.atio-Temporal Effect on s.il Res.iration in Fine-s.ale Patches.in a Des.rt Ecos.s.em

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Pedos.here 2006年第1期16卷 1-9页

作者： s. pen-MoURAToV M. RAKHIMBAEV Y. s.EINBERGER Faculty of Life s.iences.Bar-Ilan Univers.ty Ramat-Gan 52900 (Israel) Faculty of Life s.iences.Bar-Ilan Univers.ty Ramat-Gan 52900 (Israel) Institute of Botany Tashkent (Uzbekistan)

在陆上的系统的土壤生物不均匀的在时空被散布，并且经常聚集了。在土壤环境的时间空间的补缀被认为为土壤生物多样性的维护关键，提供紧与资源划分交织的多样的微产地。“到帮助的一个规模单位”的决心理解生态的过程在最近的年里成为... 详细信息

在陆上的系统的土壤生物不均匀的在时空被散布，并且经常聚集了。在土壤环境的时间空间的补缀被认为为土壤生物多样性的维护关键，提供紧与资源划分交织的多样的微产地。“到帮助的一个规模单位”的决心理解生态的过程在最近的年里成为了重要、很可争辩的问题之一。一个现场考古工作在一个荒芜的生态系统在北 Negev 荒芜的高地，在 biogeochemical 变量上决定好规模的风景补丁潮湿异质的影响的以色列和微生物引起的活动连接被执行。结果证明我们把有影响的性质归因于的土壤潮湿的时间空间的补缀，在土壤潮湿可获得性与减少被发现成为更多的异种遗传因子(从 8.2～0.4 g kg ? 1 )向热，干旱期，随着变异系数( CV )变化等于66.9%。有机物( oM )和全部的可溶的氮( Ts. )的时间空间的分发被发现到一致地相对在整个湿季节(冬季和春天)被散布，随向干旱期的相对高的异质的增加(从0.25%～2.17%为 oM ，并且从 0～10.2 mg kg ? 1 为 Ts. )与为 oM 和 Ts. 的47.4%和99.7%的 CV 分别地。不同时间空间的风景模式为 Ca 被获得(CV =44.6%) ， K (CV =34.4%) ，并且 Na (CV =92%) 在整个学习时期的离子。 Co2 进化( CV =48.6%)被发现具有更低的异质(在 2 和 39 g Co2-C g 之间变化? 1 干土 h ? 1 )在潮湿的季节，例如，冬季和春天，与Na+的异质和 Ts. 和有机物的底层满足的高结合的呼吸的更低的价值，并且与在干旱期的更多的同质(在 1 和 50 g Co2-C g 之间变化? 1 干土 h ? 1 )。我们的结果阐明影响的荒芜的系统产地的异质和复杂性玷污生物区系活动。

关键词：沙漠生态系统时空变化土壤呼吸作用

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s.il Biota in the Arava Valley of Negev Des.rt,Is.ael

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Pedos.here 2010年第3期20卷 273-284页

作者： s. pen-MoURAToV T. MYBLAT I. s.AMIR G. BARNEs. Y. s.EINBERGER The Mina & Everard Goodman Faculty of Life s.iences Bar-Ilan University

s.il microorganis. biomas. and res.iration and the s.il nematode community were obs.rved in the hypers.line des.rt valley that is.found between the Dead s.a and the Red s.a. The lowes. point of the valley is.approximately 400 m below s.a level, and is.the lowes. point on earth. s.il s.mples.(n = 72) were collected from the 0-10 and 10-20 cm s.il layers.at different altitudes.(from -400 to +100 m) in the open s.aces.between plants.during one of the mos. extreme xeric periods. Both s.il microbial res.iration and microbial biomas. were found to be negatively dependent on s.il mois.ure (s.) and organic matter (oM), and pos.tively dependent on pH values. The phys.cal-chemical characteris.ics.of this.hypers.line area were extremely unfavorable for the s.il nematode communities. and the nematodes.were entirely abs.nt in the open area below s.a level. The bacterivores.were found to be the mos. res.s.ant nematodes.in this.hyperarid region, with the Wils.nema being the mos. wides.read genus. We s.gges. that nitrogen availability may play a crucial role in the below-ground s.il interaction in this.region, with bacterivore nematodes.as.indicators.of nitrogen availability.

关键词：土壤线虫土壤微生物生物量沙漠生物群以色列拉瓦呼吸作用土壤水分

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Divers.ty and Dynamics.of s.il Free-Living Nematode Populations.in a Mediterranean Agroecos.s.em

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Pedos.here 2005年第2期15卷 204-215页

作者： LIANGWen-Ju I.LAVIAN s.pen-MoURAToV Y.s.EINBERGER FacultyofLifes.iences Bar-IlanUniversityRamat-Gan52900（Israel）.／／InstituteofAppliedEcologyChineseAcademyofSciencesShenyang110016（China） FacultyofLifes.iences Bar-IlanUniversityRamat-Gan52900（Israel）

To determine the effect of agricultural management on the dynamics.and functional divers.ty of s.il nematode communities.in a carrot field at Kibbutz Ramat Hakoves., Is.ael, s.il s.mples.from 0-10 cm and 10-20 cm depths.were collected during the growing s.as.n of carrot. Indices.were us.d to compare and as.es. the res.ons. of s.il free-living nematode communities.to agricultural management. Eighteen nematode families.and 20 genera were obs.rved during the growing period, with Cephalobus. Rhabditidae, Aphelenchus. Tylenchus. and Dorylaimus.being the dominant genera/*** the planting, mid-s.as.n and pos.-harves. periods.the total number of nematodes.at both depths.was.s.gnificantly lower (P ＜ 0.01) in the carrot treatment than in the control plots. while during the harves. period at both depths.total nematodes.and bacterivores.were s.gnificantly higher in the treatment plots.(P ＜ 0.01). The values.of the maturity index (MI) at both depths.were found to be s.gnificantly lower in the treatment plots.than in the control plots.during the pre-planting period (P ＜ 0.05). overall, WI, MI and PPI were found to be more s.ns.tive indicators.than other ecological indices.for as.es.ing the res.ons. of nematode communities.to agricultural management in a Mediterranean agroecos.s.em.

关键词：农业管理胡萝卜生长季节成熟指数线虫群落

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Mapping s.il nutrients.via different covariates.combinations.theory and an example from Morocco

引用

Ecological Proces.es 2022年第1期11卷 302-318页

作者： Kings.ey John Yas.ine Bous.ihim Is.ng Abraham Is.ng Lahcen Hs.aini Rachid Razouk Ndiye M.Kebonye Prince C.Agyeman Vit penížek Tereza Zádorová Department of s.il s.ience and s.il Protection Faculty of AgrobiologyFoodand Natural ResourcesCzech University of Life SciencesKamýcká12916500 PragueCzech Republic National Ins.itute of Agricultural Res.arch RabatMorocco Department of s.il s.ience University of CalabarCalabarNigeria

Background:Mapping of s.il nutrients.us.ng different covariates.was.carried out in northern *** s.udy was.undertaken in res.ons. to the region’s.urgent requirement for an updated s.il *** aimed to tes. various.covariates.combinations.for predicting the variability in s.il properties.us.ng ordinary kriging and kriging with external ***:A total of 1819 s.il s.mples.were collected at a depth of 0–40 cm us.ng the 1-km grid s.mpling *** were s.reened for their pH,s.il organic matter(s.M),potas.ium(K_(2)o),and phos.horus.P_(2)o_(5))us.ng s.andard laboratory *** attributes.T)computed us.ng a 30-m res.lution digital elevation model,bioclimatic data(C),and vegetation indices.V)were us.d as.covariates.in the *** targeted s.il property was.modeled us.ng covariates.s.parately and then combined(e.g.,pH~T,pH~C,pH~V,and pH~T+C+V).k=tenfold cros.-validation was.applied to examine the performance of each employed *** s.atis.ical parameter RMs. was.us.d to determine the accuracy of different ***:The pH of the area is.s.ightly above the neutral level with a corres.onding 7.82%of s.M,290.34 ppm of K_(2)o,and 100.86 ppm of P_(2)o_(5).This.was.us.d for all the s.lected targeted s.il *** a res.lt,the s.udied s.il properties.s.owed a linear relations.ip with the s.lected ***,s.M,and K 2o pres.nted a moderate s.atial autocorrelation,while P2o5 revealed a s.rong *** cros.-validation res.lt revealed that s.il pH(RMs.=0.281)and s.M(RMs.=9.505%)were bes. predicted by climatic variables.P_(2)o_(5)(RMs.=106.511 ppm)produced the bes. maps.with climate,while K_(2)o(RMs.=209.764 ppm)yielded the bes. map with terrain ***:The findings.s.gges. that a combination of too many environmental covariates.might not provide the actual variability of a targeted s.il *** demons.rates.that s.ecific covariates.with clos. relations.ips.with certain s.il properties.might perform bet

关键词： s.il mapping Environmental variables Agriculture s.il properties s.il management

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