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Towards a Leprosy-Free Country--China,2011−2018

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China CDC weekly 2020年第4期2卷 49-52页

作者： Meiwen Yu peiwen sun Le Wang Hongsheng Wang Heng Gu Xiangsheng Chen Institute of Dermatology Chinese Academy of Medical Sciences&Peking Union Medical College&National Center for Leprosy ControlChinese Center for Disease Control and PreventionNanjingJiangsuChina.

Summary What is already known about this topic?Leprosy is a chronic infectious disease that is endemic in several *** of leprosy has had targets set by World Health Organization’s(WHO)Global Strategy 2016–2020 and by China through a national leprosy-control plan(2011–2020).What is added by this report?Data from the Leprosy Management Information System in China was analyzed and showed a national prevalence of 0.178 per 100,000 and detection rate of 0.037 per 100,000 residents in *** addition,all the main targets for 2020 have been met by 2018 except for the proportion of counties or cities to reach a prevalence of less than 1/100,000 and the proportion of children cases with grade 2 disability(G2D).What are the implications for public health practice?There are still challenges remaining to close the gaps between current progress and the targets set forth by the WHO and ***,lessons learned in China in developing and implementing the national program may be invaluable for future plans to achieve and sustain elimination of leprosy at global and country level.

关键词： Lep elimination counties

An Innovative Deep Architecture for Flight Safety Risk Assessment Based on Time Series Data

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Computer Modeling in Engineering & Sciences 2024年第3期138卷 2549-2569页

作者： Hong sun Fangquan Yang peiwen Zhang Yang Jiao Yunxiang Zhao Civil Aviation Flight Technology and Flight Safety Research Base Civil Aviation Flight University of ChinaGuanghan618307China Airport Academy Civil Aviation Flight University of ChinaGuanghan618307China School of Economics and Management Civil Aviation Flight University of ChinaGuanghan618307China China Academy of Civil Aviation Science and Technology Beijing101300China Flight Training Standards Branch Civil Aviation Flight University of ChinaGuanghan618307China

With the development of the integration of aviation safety and artificial intelligence,research on the combination of risk assessment and artificial intelligence is particularly important in the field of risk management,but searching for an efficient and accurate risk assessment algorithm has become a challenge for the civil aviation ***,an improved risk assessment algorithm(PS-AE-LSTM)based on long short-term memory network(LSTM)with autoencoder(AE)is proposed for the various supervised deep learning algorithms in flight safety that cannot adequately address the problem of the quality on risk level ***,based on the normal distribution characteristics of flight data,a probability severity(PS)model is established to enhance the quality of risk assessment ***,autoencoder is introduced to reconstruct the flight parameter data to improve the data ***,utilizing the time-series nature of flight data,a long and short-termmemory network is used to classify the risk level and improve the accuracy of risk ***,a risk assessment experimentwas conducted to analyze a fleet landing phase dataset using the PS-AE-LSTMalgorithm to assess the risk level associated with aircraft hard landing *** results show that the proposed algorithm achieves an accuracy of 86.45%compared with seven baseline models and has excellent risk assessment capability.

关键词： Safety engineering risk assessment time series data autoencoder LSTM

Post-transcriptional regulation of grain weight and shape by the RBP-A-J-K complex in rice

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Journal of Integrative Plant Biology 2024年第1期66卷 66-85页

作者： Ding Ren Hui Liu Xuejun sun Fan Zhang Ling Jiang Ying Wang Ning Jiang peiwen Yan Jinhao Cui Jinshui Yang Zhikang Li Pingli Lu Xiaojin Luo State Key Laboratory of Genetic Engineering and MOE Engineering Research Center of Gene Technology School of Life SciencesFudan UniversityShanghai 200438China State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityKaifeng 475004China MOE Key Laboratory of Crop Physiology Ecology and Genetic Breeding College of AgronomyJiangxi Agricultural UniversityNanchang 330045China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural Sciences(CAAS)Beijing 100081China College of Agronomy Anhui Agricultural UniversityHefei 230036China

RNA-binding proteins(RBPs)are components of the post-transcriptional regulatory system,but their regulatory effects on complex traits remain *** an integrated strategy involving map-based cloning,functional characterizations,and transcriptomic and population genomic analyses,we revealed that RBP-K(LOC_Os08g23120),RBP-A(LOC_Os11g41890),and RBP-J(LOC_Os10g33230)encode proteins that form an RBP-A-J-K complex that negatively regulates rice yield-related *** of the RBP-A-J-K complex indicated RBP-K functions as a relatively non-specific RBP chaperone that enables RBP-A and RBP-J to function ***,RBP-J most likely affects GA pathways,resulting in considerable increases in grain and panicle lengths,but decreases in grain width and *** contrast,RBP-A negatively regulates the expression of genes most likely involved in auxin-regulated pathways controlling cell wall elongation and carbohydrate transport,with substantial effects on the rice grain filling process as well as grain length and ***,RBP-K is relatively ancient and highly conserved,whereas RBP-J and RBP-A are more ***,the RBP-A-J-K complex may represent a typical functional model for many RBPs and protein complexes that function at transcriptional and post-transcriptional levels in plants and animals for increased functional consistency,efficiency,and versatility,as well as increased evolutionary *** results clearly demonstrate the importance of RBP-mediated post-transcriptional regulation for the diversity of complex ***,rice grain yield and quality may be enhanced by introducing various complete or partial loss-of-function mutations to specific RBP genes using clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9 technology and by exploiting desirable natural tri-genic allelic combinations at the loci encoding the components of the RBP-A-J-K complex through marker-assisted select

关键词： GL11 grain weight and shape post-transcriptional regulation RNA-binding proteins

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pH和温度对8种甜味剂甜味释放特征的影响

食品与生物技术学报 2023年第5期42卷 1-11页

作者：韩仁娇卞金梅王彩云何剑 sun peiwen 杨吉武云战友钟芳夏熠珣内蒙古乳业技术研究院有限责任公司内蒙古呼和浩特010110 内蒙古伊利实业集团股份有限公司内蒙古呼和浩特010110 江南大学食品学院江苏无锡214122

为探究pH和温度对8种不同甜味剂(蔗糖、果葡糖浆、麦芽糖醇、山梨糖醇、低聚果糖、甜菊糖苷00、甜菊糖苷07和甜菊糖苷14)甜味动态释放特征的影响规律,先通过成对比较法、量值估计法和单因素方差分析,确定了在常温中性条件下,与5 g/dL蔗... 详细信息

为探究pH和温度对8种不同甜味剂(蔗糖、果葡糖浆、麦芽糖醇、山梨糖醇、低聚果糖、甜菊糖苷00、甜菊糖苷07和甜菊糖苷14)甜味动态释放特征的影响规律,先通过成对比较法、量值估计法和单因素方差分析,确定了在常温中性条件下,与5 g/dL蔗糖甜度相等的其他7种甜味剂质量浓度。进一步通过时间-强度法(time-intensity)描绘了8种甜味剂在常温中性(25℃、pH 7.0)、常温酸性(25℃、pH 4.5)和低温中性(4℃、pH 7.0)3种条件下的甜味动态释放特征。结果表明,对于大部分样品而言,酸性和低温条件均会降低最大甜味强度,其中,酸性条件对果葡糖浆和甜菊糖苷类样品的降低效果高于低温条件,而对于糖醇类、蔗糖和低聚果糖等样品,低温条件降低效果更显著。此外,各样品的整体甜味持续时间也受到酸性和低温条件的抑制而缩短,且低温条件影响更显著。因此,酸性或低温条件都会抑制不同甜味剂的甜味释放强度或释放时间,但影响程度不同;相比而言,3种条件下,在甜味动态释放特征及变化趋势上,与蔗糖的表现最为接近的是山梨糖醇,其次是果葡糖浆和低聚果糖。

关键词：时间-强度法甜味剂甜味动态释放特征 pH 温度

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MR非增强成像技术在克罗恩病诊断中的应用

国际医学放射学杂志 2019年第3期42卷 322-325页

作者：孙珮雯赵炳辉南京医科大学上海市第十人民医院临床医学院上海200072

临床上对克罗恩病(CD)的诊断主要依靠内镜和病理学检查,但其敏感性、特异性和病人顺应性均较低。扩散加权成像、扩散峰度成像、磁化传递成像及运动成像等MR非增强成像技术有利于发现CD病灶、区分CD活动性与非活动性病灶,鉴别CD炎性与纤... 详细信息

临床上对克罗恩病(CD)的诊断主要依靠内镜和病理学检查,但其敏感性、特异性和病人顺应性均较低。扩散加权成像、扩散峰度成像、磁化传递成像及运动成像等MR非增强成像技术有利于发现CD病灶、区分CD活动性与非活动性病灶,鉴别CD炎性与纤维性狭窄等,从而对内镜和病理学诊断起到协同、补充作用,亦能提高CD及其并发症的检出率。就MR非增强成像技术的进展及其在CD诊断中的应用价值进行综述。

关键词：克罗恩病扩散加权成像扩散峰度成像磁化传递成像运动成像

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基于“产、村、景”一体化的乡村规划实践

城市规划 2012年第10期36卷 58-62,92页

作者：贺勇孙佩文柴舟跃浙江大学建筑系

在不同层面上探讨了基于"产、村、景"一体化的"美丽乡村"规划实践与方法,旨在使乡村景观越过"美丽"的表象,重返乡村生产与乡村生活之中,从而使乡村经济、社会以及环境得以平衡、健康地发展。

关键词： “产村景”一体化美丽乡村建设规划策略平衡发展

浅析我国中央政府部门行政审批权的问题与改革

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科教导刊 2014年第16期 227-227页

作者：孙佩雯上海政法学院

十八大报告中提到"深化行政审批制度改革,继续简政放权,推动政府职能向创造良好发展环境、提供优质公共服务、维护社会公平正义转变",关于行政审批权的削减下方,将视线再次拉倒了行政审批权面前,我国的行政审批权随着社会的变迁也逐渐... 详细信息

十八大报告中提到"深化行政审批制度改革,继续简政放权,推动政府职能向创造良好发展环境、提供优质公共服务、维护社会公平正义转变",关于行政审批权的削减下方,将视线再次拉倒了行政审批权面前,我国的行政审批权随着社会的变迁也逐渐露出弊端,社会问题丛生。同时今年中国(上海)自由贸易区的建立,对于行政审批权的试验也更加令人关注,行政审批权在改革过程中所遇到的阻滞也需要再发展和实践中不断完善和解决。

关键词：行政审批自由裁量改革

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加强高校兼职档案员队伍建设的路径探究

文化创新比较研究 2021年第4期5卷 161-163页

作者：孙佩雯上海政法学院上海201701

在档案信息化背景下,高校兼职档案员处在档案工作的最前线,他们收集的档案质量会直接影响整个归档工作的质量与效率。如何在新形势下,做好档案的收集、保管与利用,做好档案信息化工作,兼职档案员起着至关重要的影响作用。因此要对高校... 详细信息

在档案信息化背景下,高校兼职档案员处在档案工作的最前线,他们收集的档案质量会直接影响整个归档工作的质量与效率。如何在新形势下,做好档案的收集、保管与利用,做好档案信息化工作,兼职档案员起着至关重要的影响作用。因此要对高校兼职档案员队伍的实际情况进行分析和研究,不断加强高校兼职档案员的培养,更好地为高校档案工作服务,促进归档工作科学化、规范化水平的提高。

关键词：高校兼职档案员档案管理队伍建设

新《档案法》背景下对高校档案信息化工作的思考

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兰台世界 2023年第8期 75-77页

作者：孙佩雯上海政法学院

网络信息时代的到来对传统档案工作产生了冲击,新修订的《中华人民共和国档案法》为档案工作的应对指明了方向,较之旧版《档案法》明显作出了不少调整,最为明显的就是增加了档案信息化章节。对于高校而言,档案信息化过程中也同样面临许... 详细信息

网络信息时代的到来对传统档案工作产生了冲击,新修订的《中华人民共和国档案法》为档案工作的应对指明了方向,较之旧版《档案法》明显作出了不少调整,最为明显的就是增加了档案信息化章节。对于高校而言,档案信息化过程中也同样面临许多现实问题。文章通过解读新《档案法》,分析高校档案信息化存在的问题,对进一步做好高校档案信息化工作提供可行性的意见。

关键词：档案法档案信息化高校档案数字化