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Urban Plant Diversity in Relation to Land Use Types in Built-up Areas of Beijing

Chinese Geographical Science 2018年第1期28卷 100-110页

作者： GUO peipei su Yuebo WAN Wuxing LIU Weiwei ZHANG Hongxing suN Xu OUYANG Zhiyun WANG Xiaoke State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences College of Life Science Hebei Normal University Beijing Urban Ecosystem Research Station Research Center for Eco-Environmental Sciences Chinese Academy of Sciences

Urban plants provide various ecosystem services and biodiversity for human well-being. It is necessary to examine the plant species and functional traits composition and the influencing factors. In this study, a field survey was conducted using the tessellation-randomized plot method to assess the plant species and functional traits variability in greenspaces across eight land use types(LUTs) in the built-up areas of Beijing, China. Results showed that the woody plants in the built-up areas of Beijing comprised 85 non-native species(57%), 21 pollen-allergenic species(14%), and 99 resistant species(67%). Residential areas, community parks and institutional areas had higher woody plant species richness than other LUTs. Native and extralimital native species were more widespread than exotic species. Proportions of species with resistances were low except for cold-and drought-resistance; consequently, a high intensity of management and maintenance is essential for survival of plants in this urban area. Caution should be exerted in selecting plant species with resistance to harsh conditions in different LUTs. Housing prices, distances from the urban center, years since the establishment of LUTs and greening rate were strongly correlated with the plant functional traits and species diversity. Urban forest managers should consider plant functional traits and LUT-specific strategies to maximize both forest and human health.

关键词： functional trait native species extralimital native exotic resistant species Beijing

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Defect engineering of molybdenum disulfide through ion irradiation to boost hydrogen evolution reaction performance

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Nano Research 2019年第7期12卷 1613-1618页

作者： Cheng sun peipei Wang Hao Wang Chuan Xu Juntong Zhu Yanxia Liang Ying su Yining Jiang Wenqi Wu Engang Fu Guifu Zou Soochow Institute for Energy and Materials Innovations & Key Laboratory of Advanced Carbon Materials and Wearable Energy Technologies oj Jiangsu Province Soochow UniversitySuzhou 215006China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

The inert basal plane of molybdenum disulfide (MoS2) restrains its further hydrogen evolution reaction (HER) *** work attempts ion irradiation to activate inert basal plane of MoS2 nanosheet to improve its electrocatalytic *** results demonstrate the sulphur vacancies generated by ion irradiation on the basal plane of MoS2 mainly boost the efficiency of HER *** moderate fluence of carbon ion irradiation gains the optimum HER performance with an onset potential of 77 mV and Tafel slope of 66 mV/dec.

关键词： MoS2 nanosheet ion irradiation electrocatalyst hydrogen evolution reaction sulphur vacancy

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痛风性关节炎患者骨代谢标志物异常的相关因素分析

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浙江医学 2024年第24期46卷 2589-2594页

作者：王鑫苏培培李秦李华燕陈禛恒牛源源孙千惠杜明瑞河南中医药大学第一附属医院风湿病科郑州450000 河南中医药大学第一临床医学院

目的探讨痛风性关节炎(GA)患者血清骨代谢标志物与尿酸(UA)、脂代谢和肾功能相关指标的相关性,为GA患者骨破坏的早期预防提供临床参考。方法前瞻性选取2023年1至12月就诊于河南中医药大学第一附属医院的60例经双源CT检查的GA患者,其中... 详细信息

目的探讨痛风性关节炎(GA)患者血清骨代谢标志物与尿酸(UA)、脂代谢和肾功能相关指标的相关性,为GA患者骨破坏的早期预防提供临床参考。方法前瞻性选取2023年1至12月就诊于河南中医药大学第一附属医院的60例经双源CT检查的GA患者,其中有痛风石30例(痛风石组),无痛风石30例(无痛风石组),并以同期15名健康体检者作为对照组。抽取3组研究参与者空腹静脉血,检测生化指标;采用ELISA法检测NF-κB受体活化因子配体(RANKL)、骨保护素(OPG)、人Ⅰ型胶原交联竣基端肽(CTX)等骨代谢标志物水平,并对以上指标进行相关性分析。结果痛风石组患者UA、LDL、TG、TC、血肌酐(Scr)水平均高于对照组,HDL低于对照组(均P<0.05);无痛风石组患者UA、TG、TC水平均高于对照组(均P<0.05);痛风石组患者TG、TC、Scr水平均高于无痛风石组(均P<0.05),HDL水平低于无痛风石组(P<0.05);痛风石组患者RANKL、OPG、CTX水平均高于对照组(均P<0.05),OPG/RANKL低于对照组(P<0.05);无痛风石组患者RANKL水平高于对照组(P<0.05);痛风石组患者RANKL、OPG水平均高于无痛风石组(均P<0.05)。相关性分析显示,RNAKL水平与UA、LDL、TG、TC、Scr呈正相关,与HDL呈负相关(均P<0.05);OPG水平与UA、LDL、TG、TC、Scr呈正相关(均P<0.05);OPG/RANKL与Scr呈负相关(P<0.05)。结论GA患者UA高表达,伴随骨代谢标志物异常、脂代谢紊乱和肾功能减退,其中痛风石组更为显著。骨代谢标志物水平与UA、LDL、HDL、TG、TC及Scr水平显著相关。

关键词：痛风性关节炎骨代谢痛风石骨质破坏脂代谢

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First total synthesis,antitumor evaluation and target identification of mornaphthoate E:A new tubulin inhibitor template acting on PI3K/Akt signaling pathway

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2177-2193页

作者： peipei Shan Tao Ye Ying-De Tang Hui Song Chao Wang Kongkai Zhu Feifei Yang Shi-Lei Zhang Pei-Wen su Shuanhu Gao Hua Zhang Institute of Translational Medicine the Affiliated Hospital of Qingdao UniversityCollege of MedicineQingdao UniversityQingdao 266021China School of Biological Science and Technology University of JinanJinan 250022China Advanced Medical Research Institute Cheeloo College of MedicineShandong UniversityJinan 250012China College of Pharmaceutical Sciences Soochow UniversitySuzhou 215127China School of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200062China

Mornaphthoate E(MPE)is a prenylated naphthoic acid methyl ester isolated from the roots of a famous Chinese medicinal plant Morinda officinalis and shows remarkable cytotoxicity against several human tumor cell *** the current project,the first total synthesis of(±)-MPE was achieved in seven steps and 5.6%overall *** the in vitro anti-tumor activity of MPE was first assessed for both enantiomers in two breast cancer cells,with the levoisomer exerting slightly better *** in vivo anti-tumor effect was further verified by applying the racemate in an orthotopic autograft mouse ***,MPE exerted promising anti-metastasis activity both in vitro and in vivo and showed no obvious toxicity on mice at the therapeutic *** investigations demonstrated that MPE acted as a tubulin polymerization stabilizer and disturbed the dynamic equilibrium of microtubules via regulating PI3K/Akt *** conclusion,our work has provided a new chemical template for the future design and development of next-generation tubulin-targeting chemotherapies.

关键词： Mornaphthoate E Tubulin inhibitor Antitumor Anti-metastasis Breast cancer PI3K/Akt

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An Organic Solvent-Assisted Intercalation and Collection (OAIC) for Ti_(3)C_(2)T_(x) MXene with Controllable Sizes and Improved Yield

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Nano-Micro Letters 2021年第11期13卷 428-440页

作者： Danyao Qu Yingying Jian Lihao Guo Chen su Ning Tang Xingmao Zhang Wenwen Hu Zheng Wang Zhenhuan Zhao Peng Zhong peipei Li Tao Du Hossam Haick Weiwei Wu School of Advanced Materials and Nanotechnology Xidian UniversityXi’anShaanxi 710126People’s Republic of China School of Aerospace Science and Technology Xidian UniversityXi’anShaanxi 710126People’s Republic of China Department of Chemical Engineering and Russell Berrie Nanotechnology Institute Technion-Israel Institute of Technology3200003 HaifaIsrael

A good method of synthesizing Ti_(3)C_(2)T_(x)(MXene)is critical for ensuring its success in practical applications,e.g.,electromagnetic interference shielding,electrochemical energy storage,catalysis,sensors,and *** main concerns focus on the moderation of the approach,yield,and product ***,a modified approach,organic solvent-assisted intercalation and collection,was developed to prepare Ti_(3)C_(2)T_(x) *** new approach simultaneously solves all the concerns,featuring a low requirement for facility(centrifugation speedsuperb example for the synthesis of other MXene materials in laboratory,but sheds new light for the future mass production of Ti_(3)C_(2)T_(x) MXene.

关键词： Two-dimensional materials MXenes Controllable sizes High yield

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Collagen-binding basic fibroblast growth factor improves functional remodeling of scarred endometrium in uterine infertile women: a pilot study

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Science China(Life Sciences) 2019年第12期62卷 1617-1629页

作者： peipei Jiang Xiaoqiu Tang Huiyan Wang Chenyan Dai Jing su Hui Zhu Minmin Song Jingyu Liu Ziqing Nan Tong Ru Yaling Li Jingmei Wang Jun Yang Bing Chen Jianwu Dai Yali Hu Department of Obstetrics and Gynecology The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Center for Reproductive Medicine Department of Obstetrics and GynecologyThe Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Nanjing Drum Tower Hospital Chinese Academy of Medical Science&Peking Union Medical CollageNanjing 210008China Department of Pathology The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008China Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100190China

Intrauterine adhesion(IUA) is a common cause of uterine infertility and one of the most severe clinical features is endometrial fibrosis namely endometrial scarring for which there are few cures currently. Blocked angiogenesis is the main pathological change in the scarred endometrium. The fibroblast growth factor 2(b FGF), a member of FGF family, is usually applied to promote healing of refractory ulcer and contributes to angiogenesis of tissues. In this study, the sustained-release system of b FGF100 μg was administrated around scarred endometrium guiding by ultrasound every 4 weeks in 18 patients(2–4 times). Results showed that after treatment, the menstrual blood volume, endometrial thickness and the scarred endometrial area were *** study showed blood vessel density increased obviously. Three patients(3/18) achieved pregnancy over 20 gestational weeks. Therefore, administrating the b FGF surrounding scarred endometrium may provide a new therapeutic approach for the patients with endometrial fibrosis.

关键词： intrauterine adhesion CBD-bFGF endometrial scarring uterine infertility thin endometrium endometrial reconstruction

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Information Transfer Index-A Promising Measure of the Corticomusclar Interaction

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Engineering（科研） 2013年第10期5卷 57-61页

作者： Ping Xie peipei Ma Xiaoling Chen Xiaoli Li Yuping su Department of Rehabilitation Qinhuangdao People’s Hospital Qinhuangdao China Institute of Electrical Engineering Yanshan University Qinhuangdao China

It is generally believed that a major cause of motor dysfunction is the impairment in neural network that controls movement. But little is known about the underlying mechanisms of the impairment in cortical control or in the neural connections between cortex and muscle that lead to the loss of motor ability. So understanding the functional connection between motor cortex and effector muscle is of utmost importance. Previous study mostly relied on cross-correlation, coherence functions or model based approaches such as Granger causality or dynamic causal modeling. In this work the information transfer index (ITI) was introduced to describe the information flows between motor cortex and muscle. Based on the information entropy the ITI can detect both linear and nonlinear interaction between two signals and thus represent a very comprehensive way to define the causality strength. The applicability of ITI is investigated based on simulations and electroencephalogram (EEG), surface electromyography (sEMG) recordings in a simple motor task.

关键词： Information Theory Information Transfer Index Corticomuscular Interaction

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Expression analysis of renal genes identified from spotted scat（Scatophagus argus） in response to abrupt hypoosmotic shock

Expression analysis of renal genes identified from spotted s...

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2014年中国水产学会学术年会

作者： Xingjiang Mu Maoliang su Lang Gui Xuemei Liang peipei Zhang Junbin Zhang Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources Ministry of Education College of Fisheries and Life Science Shanghai Ocean University

Scatophagus argus, a euryhaline fish, is notable for its ability to tolerate a wide range of environmental salinities and especially for its endurance to a rapid, marked reduction in salinity. Therefore, S. argus is a suitable model for studying the molecular mechanisms mediating abrupt hyperosmoregulation. After transferred from salt water（SW） to freshwater（FW）, S. argus showed a sharply decrease in the serum osmotic pressure within one hour and then the pressure maintained at a new balance during a week. To explain this phenomenon and understand the molecular responses to an abrupt hypoosmotic shock, hypoosmotic stress responsive genes were identified based on two suppression subtractive hybridization（SSH） c DNA libraries from the kidneys of S. argus that had been transferred from SW to FW. After trimming and blasting, 52 ESTs were screened out from the subtractive library. Among them, 11 genes were significantly up-regulated（p＜0.05）. Using quantitative real-time PCR, the kinetics studies of gene expression levels were developed for 1 week after the transfer. A significant variation in the expression of these genes occurred within 12 hours after the hypoosmotic shock, except for growth hormone（GH） and polyadenylate binding protein 1（PBP1）, which were significantly up-regulated 2 days post-transfer. Our results suggest different functional roles for these genes in response to hypoosmotic stress during the stress response phase（1hpt-12hpt） and stable phase（12hpt-7dpt）. Furthermore, the plasma growth hormone level was detected to be remarkably elevated at 1 hpt and 24 hpt following abrupt hypoosmotic shock. Meanwhile, several haematological parameters, hemoglobin（HGB）, red blood cell（RBC） and mean cellular hemoglobin concentration（MCHC） were observed to be considerably increased at 12 hpt and 2 dpt compared with that of control group. Our results provide a solid basis to conduct future studies on the osmoregulatory mechanisms in the euryhaline fish.

关键词： SSH gene expression hypoosmotic shock Scatophagus argus

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高强钢组合Y形偏心支撑钢框架抗震性能试验研究

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建筑结构学报 2014年第7期35卷 89-96页

作者：段留省苏明周焦培培郝麒麟西安建筑科技大学结构与抗震教育部重点实验室陕西西安710055

高强钢组合Y形偏心支撑钢框架是耗能梁段采用较低屈服点钢材、其他构件采用高强钢的双重抗侧力结构体系。为研究其抗震性能,对4个1∶2缩尺的单层单跨高强钢组合Y形偏心支撑钢框架平面试件进行了单调和循环加载试验。根据耗能梁段长度将... 详细信息

高强钢组合Y形偏心支撑钢框架是耗能梁段采用较低屈服点钢材、其他构件采用高强钢的双重抗侧力结构体系。为研究其抗震性能,对4个1∶2缩尺的单层单跨高强钢组合Y形偏心支撑钢框架平面试件进行了单调和循环加载试验。根据耗能梁段长度将试件分为剪切屈服型和弯曲屈服型两类,分别研究了每类试件的破坏模式和主要抗震性能指标。研究结果表明,该结构耗能能力强、延性好,剪切屈服型试件的承载力比弯曲屈服型试件的高,延性也好于后者,相同位移下耗散的能量也较后者大。循环加载时,剪切屈服型试件的破坏集中于耗能梁段,此时钢框架基本处于弹性工作状态,残余变形较小,是一种有利于震后修复的双重抗侧力体系。

关键词：高强钢框架 Y形偏心支撑耗能梁段单调加载循环加载抗震性能

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高温高压烧结制备PCBN陶瓷的微观结构与性能

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机械工程材料 2022年第9期46卷 29-33,69页

作者：苏君冯佩佩河南工业职业技术学院南阳473000

以ZrO、AlO和铝粉作为结合剂,通过六面顶压机在高温(1 300~1 600℃)高压(5.5 GPa)条件下烧结制备聚晶立方氮化硼(PCBN)陶瓷,研究了烧结温度对陶瓷物相组成、力学性能以及加工离心铸铁时切削性能的影响。结果表明:不同温度烧结PCBN陶瓷... 详细信息

以ZrO、AlO和铝粉作为结合剂,通过六面顶压机在高温(1 300~1 600℃)高压(5.5 GPa)条件下烧结制备聚晶立方氮化硼(PCBN)陶瓷,研究了烧结温度对陶瓷物相组成、力学性能以及加工离心铸铁时切削性能的影响。结果表明:不同温度烧结PCBN陶瓷的主晶相均为cBN、m-ZrO、t-ZrO、AlO、AlN和ZrN,结合相颗粒均匀地分散在cBN基体上;随着烧结温度的升高,cBN与结合相的结合更加紧密,陶瓷的相对密度、硬度、抗弯强度和断裂韧度增大;当烧结温度为1 600℃时,陶瓷的综合力学性能最好,硬度、抗弯强度和断裂韧度分别达到32.87 GPa,850.3 MPa,5.1 MPa·m;当烧结温度为1 400℃和1 500℃时,PCBN陶瓷刀具在切削离心铸铁棒总长度为10 km时,其后刀面磨损量仅分别为171,166μm,切削性能较好。

关键词：聚晶立方氮化硼(PCBN) 结合剂力学性能切削性能

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