检索结果-南通市图书馆

Intestinal microbiota links to allograft stability after lung transplantation: a prospective cohort study

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2023年第10期8卷 4816-4824页

作者： Junqi Wu Chongwu Li peigen gao Chenhong Zhang Pei Zhang Lei Zhang Chenyang Dai unpeng Zhang Bowen Shi Mengyang Liu Junmeng Zheng Bo Pan Zhan Chen Chao Zhang Wanqing Liao Weihua Pan Wenjie Fang Chang Chen Department of Thoracic Surgery Shanghai Pulmonary HospitalSchool of MedicineTongji UniversityShanghaiChina Shanghai Engineering Research Center of Lung Transplantation ShanghaiChina State Key Laboratory of Microbial Metabolism School of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghaiChina Department of Thoracic Surgery Changhai HospitalNaval Medical UniversityShanghaiChina Department of Thoracic Surgery The First Affliated Hospital of Guangzhou Medical UniversityGuangzhouChina Department of Cardiovascular Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouChina Department of Dermatology Shanghai Key Laboratory of Molecular Medical MycologyShanghai Changzheng HospitalNaval Medical UniversityShanghaiChina Adfontes(Shanghai)Bio technology Co. LtdShanghaiChina

Whether the alternated microbiota in the gut contribute to the risk of allograft rejection(AR)and pulmonary infection(Pl)in the setting of lung transplant recipients(LTRs)remains unexplored.A prospective multicenter cohort of LTRs was identified in the four lung transplant *** fecal and serum specimens were collected and divided into AR,Pl,and event-free(EF)groups according to the diagnosis at *** samples were determined by metagenomic sequencing.

关键词： prospective lung allograft

W-band CMOS beamforming ICs and integrated phased-array antennas with 20+ Gb/s data rates

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第11期67卷 300-316页

作者： Dixian ZHAO peigen YU Shan JIANG Weihan gao Pingyang HE Huiqi LIU School of Information Science and Engineering Southeast University Purple Mountain Laboratories Chengdu Xphased Technology Co. Ltd.

This article presents the design and implementation of W-band transmitter(TX) and receiver(RX) phased-array antennas, which leverage CMOS and printed circuit board(PCB) technologies to integrate the phased-array antennas with eight-channel beamforming ICs. The beamforming IC applies the variable gain amplifier(VGA) with fractional bits and the vector-modulated variable gain phase shifter(VGPS) for wide range and high precision of gain and phase shifting, providing moderate power gain. The phased-array board consists of 384 TX and 384 RX antenna elements, along with 48 TX and 48 RX beamforming *** also incorporates Wilkinson power dividers/combiners, a power management system, and a beamforming control module, all integrated into a cost-effective multi-layer PCB. Fabricated in 65-nm bulk CMOS, the IC achieves 3° RMS phase error for phase shifting and 0.5 d B RMS gain error for gain shifting, ensuring high precision of antenna pointing. The over-the-air(OTA) measurement of the proposed W-band phased-array antennas achieves a 64-QAM constellation with a symbol rate of 3.5 GS/s, resulting in raw data rates of21 Gb/s.

关键词： W-band phased array CMOS Gigabit wireless link antenna on PCB

同方期刊数据库

Integrating single Ni site and PtNi alloy on two-dimensional porous carbon nanosheet for efficient catalysis in fuel cell

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第8期17卷 6916-6921页

作者： Fangyao Zhou Yaner Ruan Feng Li Lin Tian Mengzhao Zhu Wenan Tie Xiaoyan Tian Bo Wang peigen Liu Jie Xu Xiaoping gao Peng Li Huang Zhou Yuen Wu Key Laboratory of Precision and Intelligent Chemistry University of Science and Technology of ChinaHefei 230026China Shanxi Yanchang Petroleum(Group)Co.Ltd. Xian 710065China College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou 325035China

The performance of catalyst depends on the intrinsic activity of active sites and the structural characteristics of the ***,we simultaneously integrate single nickel(Ni)sites and platinum-nickel(PtNi)alloy nanoparticles(NPs)on a two-dimensional(2D)porous carbon nanosheet,demonstrating remarkable catalytic performance in the oxygen reduction reaction(ORR).The single Ni sites can activate the oxygen molecules into key oxygen-containing intermediate that is further efficiently transferred to the adjacent PtNi alloy NPs and rapidly reduced to H_(2)O,which establishes a relay catalysis between active *** porous structure on the carbon nanosheet support promotes the transfer of active intermediates between these active sites,which assists the relay catalysis by improving mass ***,the obtained catalyst demonstrates a half-wave potential of up to 0.942 V,a high mass activity of 0.54 A·mgPt^(−1),and negligible decay of activity after 30,000 cycles,which are all superior to the commercial Pt/C catalysts with comparable loading of *** theoretical calculation results reveal that the obtained catalyst with defect structure of carbon support presents enhanced relay catalytic effect of PtNi alloy NPs and single Ni sites,ultimately realizing improved catalytic *** work provides valuable inspiration for developing low platinum loading catalyst,integrating single atoms and alloy with outstanding performance in fuel cell.

关键词： two-dimensional porous carbon nanosheet Pt-based alloy single atom catalysts relay effect proton-exchange membrane fuel cells

Improved gray wolf optimizer for distributed flexible job shop scheduling problem

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2022年第9期65卷 2105-2115页

作者： LI XinYu XIE Jin MA QingJi gao Liang LI peigen State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan 430074China

The distributed flexible job shop scheduling problem(DFJSP),which is an extension of the flexible job shop scheduling problem,is a famous NP-complete combinatorial optimization *** problem is widespread in the manufacturing industries and comprises the following three subproblems:the assignment of jobs to factories,the scheduling of operations to machines,and the sequence of operations on ***,studies on DFJSP are seldom because of its *** paper proposes an effective improved gray wolf optimizer(IGWO)to solve the aforementioned *** this algorithm,new encoding and decoding schemes are designed to represent the three subproblems and transform the encoding into a feasible schedule,*** crossover operators are developed to expand the search space.A local search strategy with the concept of a critical factory is also proposed to improve the exploitability of *** schedules can be obtained by changing factory assignments and operation sequences in the critical *** proposed IGWO algorithm is evaluated on 69 famous benchmark instances and compared with six state-of-the-art algorithms to demonstrate its efficacy considering solution quality and computational *** results show that the proposed algorithm has achieved good ***,the proposed IGWO updates the new upper bounds of 13 difficult benchmark instances.

关键词： distributed and flexible job shop scheduling gray wolf optimizer critical factory

Editorial for the Special Issue on Intelligent Manufacturing

在线全文

学校读者我要写书评

暂无评论

Engineering 2021年第6期7卷 704-705页

作者： peigen Li Andrew Kusiak Liang gao Weiming Shen The State Key Laboratory of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China Department of Industrial and Systems Engineering The University of IowaIowa CityIA 52242-1527USA

Intelligent manufacturing is the development trend of manufac-turing *** comprises the deep integration of new-genera-tion information and communication technologies(i.e.,fifth generation mobile networks(5G),artificial intelligence,the Indus-trial Internet,etc.)with advanced manufacturing technologies,covering the whole life cycle of a product,including design,pro-duction,logistics,services,and so *** it is largely based on automation and machine intelligence,humans play essential roles in intelligent manufacturing.

关键词： services Intelligent artificial

Editorial for the Special Issue on Intelligent Manufacturing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2019年第4期5卷 595-596页

作者： peigen Li Vladimir Marik Liang gao Weiming Shen The State Key Laboratory of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China Czech Institute of Informatics Robotics and CyberneticsCzech Technical University in PraguePrague 16000Czech Republic National Research Council OttawaON K1A 0R6Canada

Intelligent manufacturing is represented by a deep integration of advanced information and communication technologies and advanced manufacturing *** runs through the whole life-cycle of product design,manufacturing,services,and *** intelligent product is the center of intelligent manufacturing,while the intelligent production is the main activity and an intelligent service-centered industrial mode is the *** intelligent manufacturing,manufacturing systems become increasingly agile,with higher quality and efficiency,personalized customization,and environmental *** manufacturing technology is becoming a major trend in the development of the manufacturing industry around the world.

关键词： becoming intelligent agile

Study on the morphology, crystalline structure and thermal properties of yam starch acetates with different degrees of substitution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2008年第9期51卷 859-865页

作者： WANG Xu gao WenYuan ZHANG LiMing XIAO peigen YAO LiPing LIU Yi LI KeFeng XIE WeiGuang School of Pharmaceutical Science and Technology Tianjin UniversityTianjin 300072China College of Bioengineering Tianjin University of Science and TechnologyTianjin 300457China Institute of Medicine Plant Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100094China College of Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 300193China

This study was carried out to understand and establish the changes in physicochemical properties of starch extracted from Chinese yam (Dioscorea opposita Thunb.) after acetylation. Yam starch acetates with different degrees of substitution (DS) were prepared by the reaction of yam starch with glacial acetic acid/acetic anhydride using sulfuric acid as the catalyst. Their formation was confirmed by the presence of the carbonyl signal around 1750 cm?1 in the Fourier transform infrared (FT-IR) spectra. The thermal behavior of the native starch and starch acetate were investigated using thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). The results reveal that the starch acetates are more thermally stable than the native starch. The starch esters showed 50% weight loss at temperatures from 328°C to 372°C, while the native starch underwent 50% weight loss at 325°C. The glass transition temperature (T g) of the starch decreased from 273°C to 226°c. The X-ray diffraction (XRD) patterns could be classified as typical of the C-type for yam starch. X-ray diffraction also showed the loss of the ordered C-type starch crystalline structure and the degree of crystallinity of starch decreased from 36.10% to 10.96% with the increasing DS. The scanning electron microscopy (SEM) suggested that the most of the starch granules disintegrated with many visible fragments with the increasing DS.

关键词： yam starch acetate physicochemical characterization

直接抗病毒药物治疗六例丙型肝炎病毒相关性皮肤损害患者的回顾性研究

在线全文

学校读者我要写书评

暂无评论

中华实验和临床感染病杂志（电子版） 2020年第6期14卷 507-512页

作者：赵蕴玉贺彩妮高培根刘莹姚雷清高蓉刘佳姝魏伏李慎朱龙飞李政霄纪泛扑西安交通大学第二附属医院感染科西安市710004 西安交通大学第二附属医院皮肤科西安市710004 西安市第四医院重症医学科西安市710004 陕西省疾控中心病毒所西安市710004 西安交通大学第二附属医院生物诊断与治疗国家地方联合工程中心西安市710004 陕西省肝脾疾病临床医学研究中心西安市710004

目的探讨基于索磷布韦方案治疗丙型肝炎病毒(HCV)相关性皮肤损害的疗效和安全性。方法回顾性分析2016年2月至2019年9月西安交通大学第二附属医院收治的6例HCV相关性皮肤损害患者接受基于索磷布韦方案治疗的效果和安全性。评估其持续病... 详细信息

目的探讨基于索磷布韦方案治疗丙型肝炎病毒(HCV)相关性皮肤损害的疗效和安全性。方法回顾性分析2016年2月至2019年9月西安交通大学第二附属医院收治的6例HCV相关性皮肤损害患者接受基于索磷布韦方案治疗的效果和安全性。评估其持续病毒学应答(SVR12)率,治疗过程和治疗结束后肝功能和皮损症状的变化以及安全性。结果6例患者年龄25~56岁;其中5例女性;2例肝硬化;3例基因型为HCV 1b,3例基因型为HCV 2a。皮损分别表现为阴囊湿疹、结节性痒疹、结节性红斑、扁平苔藓、干燥综合征和混和冷球蛋白血症相关皮损。2例患者病理确诊为HCV相关性皮损,4例患者临床诊断为HCV相关性皮损。患者接受索磷布韦/维帕他韦(3例)、索磷布韦/雷迪帕韦(2例)12周或索磷布韦/利巴韦林(1例)24周治疗。与基线水平相比,治疗结束或随访12周的丙氨酸氨基转移酶(ALT)显著降低、白蛋白(ALB)不变或升高,6例患者均获得SVR12且皮损均明显缓解。3例患者(阴囊湿疹、结节性痒疹、干燥综合征)皮损完全治愈,其他皮损包括结节性红斑、扁平苔藓、混和冷球蛋白血症相关皮损明显缓解,但需要接受免疫抑制剂和(或)细胞毒药物维持治疗。治疗期间未出现明显不良反应,随访期间皮损无复发。结论HCV可引起不同的肝外皮肤表现,基于索磷布韦的无干扰素方案治疗HCV相关皮肤损害有效且安全性良好。对于皮肤疾病经对症治疗后效果欠佳者,需要尽早行HCV筛查,确诊HCV感染后建议尽快给予抗病毒治疗。

关键词：肝炎病毒丙型肝外临床表现皮肤抗病毒药索磷布韦

肺移植围手术期预后风险因素分析及术后气管插管延迟拔管风险预测

在线全文

学校读者我要写书评

暂无评论

中华器官移植杂志 2023年第11期44卷 645-652页

作者：高培根张磊沈下贤张培戴晨阳李玉萍何文新陈乾坤姜格宁陈昶同济大学附属上海市肺科医院胸外科、上海肺移植工程技术研究中心上海200433

目的探究影响肺移植围手术期预后的风险因素,构建肺移植手术后延迟拔管的风险预测模型。方法回顾性分析2020年1月1日至2022年12月31日在同济大学附属上海市肺科医院接受肺移植的104例受者资料。根据受者肺移植术后气管插管拔除时间,划... 详细信息

目的探究影响肺移植围手术期预后的风险因素,构建肺移植手术后延迟拔管的风险预测模型。方法回顾性分析2020年1月1日至2022年12月31日在同济大学附属上海市肺科医院接受肺移植的104例受者资料。根据受者肺移植术后气管插管拔除时间,划分为正常拔管组(拔管时间≤术后72 h,77例)和延迟拔管组(拔管时间>72 h或再次插管,27例),比较两组受者的基线特征、术前原发病诊断、冷缺血时间、移植手术方式等情况,根据受者院内的病情转归分为院内死亡组(10例)和正常出院组(94例),比较两组的临床资料,找到肺移植死亡的可能风险因素,综合6个肺移植围手术期相关变量进行单因素及多因素logistic回归分析,根据多因素logistic回归模型构建延迟拔管预测Nomogram评分表。绘制受试者工作特征曲线(receiver operator characteristic curve,ROC curve)及决策曲线分析(decision curve analysis,DCA),评价模型预测延迟拔管效能及临床应用价值。结果本研究104例肺移植受者术后院内死亡率为9.6%,术后延迟气管插管拔管率为26.0%,术后延迟气管插管拔除是影响肺移植受者围手术期预后的关键风险因素(OR=2.007,95%CI:1.117~3.444,P=0.008)。针对延迟拔管预测分析,冷缺血时间具有最佳预测效能,其与所构建的风险预测模型的ROC曲线下面积(area under the curve,AUC)分别为0.75(95%CI:0.69~0.81)和0.87(95%CI:0.82~0.91)。结论手术后气管插管延迟拔除是肺移植术后早期预后不良的重要标志。本研究所构建风险预测模型,能够有效预测肺移植手术后气管插管延迟拔除,从而实现对高危受者预防性干预,提高肺移植术后早期存活率。

关键词：肺移植围手术期气管插管预后