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ZYX promotes invasion and metastasis of gastric cancer cells via WNK1/SNAI1axis

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Genes & Diseases 2024年第2期11卷 564-567页

作者： Yi Jiang Dongfang Xiang Xianmei wen Mingmin He Yan Qin Xiaoxue Yao Zexuan Yan Xiuli Geng Yong ren Xiongwei Cai Youhong Cui Yan Wang Institute of Pathology and Southwest Cancer Center Southwest HospitalArmy Medical University (Third Military Medical University)Chongqing 400038China Department of Pathology General Hospital of Central Theater Command of PLAWuhanHubei 430070China Department of Obstetrics and Gynecology Southwest HospitalArmy Medical University (Third Military Medical University)Chongqing 400038China Department of Pharmacy The Hospital of 83rd Group of PLAXinxiangHenan 453000China Department of Gynecology Chongqing Health Center for Women and ChildrenWomen and Children's Hospital of Chongqing Medical UniversityChongqing 400013China

Gastric cancer(GC)is the third most common cause of cancer death globally and a large portion of patients are diagnosed at advanced stages with cancer invasion and metastasis1,***,the mechanisms underlying the invasion and metastasis of GC remain to be *** plays critical roles in cell mobility via cytoskeleton regulation in various cell types.3 In this study,we further reported that ZYX promoted migration,invasion,and metastasis of GC ***,ZYX promoted WNK1 activation and SNAl1 up-regulation,inducing epithelial-mesenchymal transition(EMT)to enhance the mobility of GC *** of WNK1 impaired the mobility of GC ***,ZYX/WNK1 could be potential therapeutic targets for GC treatment.

关键词： WNK1 invasion metastasis

Envisioning Water-Resilient Cities Through the Lens of Blue-Green-Grey Solutions

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Engineering 2024年第5期36卷 1-2页

作者： Nan-Qi ren Glen Daigger School of Civil and Environmental Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Urban Water Resource and Environment Harbin Institute of TechnologyHarbin 150090China Department of Civil and Environmental Engineering University of MichiganAnn ArborMI 48109USA

Cities are dynamic systems,and the urban water systems within them can be evolved to provide water services to both humans and the environment while also enhancing the broader urban *** is done by embracing innovation and technological advancement while focusing on increased service to the human population and the local and broader *** the contemporary era,characterized by the rise of low-carbon and intelligent technologies,the swift pace of socioeconomic expansion highlights the critical need to address issues of urban water security and environmental *** escalating resource and environmental constraints,adopting holistic blue-green-grey strategies becomes imperative for the sustainable governance of urban water *** integrated approach is needed to navigate the intricate challenges of urban water dynamics while fostering enhanced ecological performance and resilience.

关键词： services urban advancement

跨学科翻译教育的模式创新:背景、理念与实施

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中国外语 2024年第5期21卷 75-83页

作者：任文北京外国语大学

随着社会需求的多元化和现实问题的复杂化,单一学科教育的局限性日渐凸显,跨学科教育成为高等教育发展的新趋势,跨学科翻译教育也逐渐得到学界的重视,但尚缺乏实证研究的结果呈现。本文通过探讨我国跨学科翻译教育的产生背景和设计理念... 详细信息

随着社会需求的多元化和现实问题的复杂化,单一学科教育的局限性日渐凸显,跨学科教育成为高等教育发展的新趋势,跨学科翻译教育也逐渐得到学界的重视,但尚缺乏实证研究的结果呈现。本文通过探讨我国跨学科翻译教育的产生背景和设计理念,描述北京外国语大学高级翻译学院和国际新闻与传播学院联合开展的“翻译与国际传播”跨学科方向“四合”模式的内涵,举隅融合式教学方法,并进行部分实证数据分析,论证跨学科翻译教育的必要性与可行性,以期为未来更多的跨学科人才培养提供理论参考和实践借鉴。

关键词：跨学科翻译教育背景理念实施 “翻译与国际传播” “四合”模式

Improved Simulation of Summer Heavy Rainfall over Beijing and Henan by the YHGSM with Updated Subgrid Orographic Parameters

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Journal of Meteorological Research 2024年第3期38卷 504-529页

作者： Yingjie WANG Jianping WU Kaijun ren College of Computer Science and Technology National University of Defense TechnologyChangsha410600China College of Meteorology and Oceanography National University of Defense TechnologyChangsha410600China

In numerical weather prediction(NWP),the parameterization of orographic drag plays an important role in representing subgrid orographic *** subgrid orographic parameters are the key input to the parameterization of orographic ***,the subgrid orographic parameters in most NWP models were produced based on elevation datasets generated many years ago,with a coarse resolution and low *** this paper,using the latest high-quality elevation data and considering the applicable scale range of the subgrid orographic parameters,we construct the orographic parameters,including the subgrid orographic standard deviation,anisotropy,orientation,and slope,that are required as input to the orographic gravity wave drag(OGWD)***,we introduce the newly constructed orographic parameters into the Yin-He Global Spectral Model(YHGSM),optimize the description of the orographic effect in the model,and improve the simulation of two typical heavy rainfall events in Beijing and Henan.

关键词： subgrid orographic parameters orographic drag heavy rainfall Yin-He Global Spectral Model(YHGSM) parameterization

On entire solutions of some Fermat type differential-difference equations

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 69-88页

作者： LONG Jian-ren QIN Da-zhuan School of Mathematical Sciences Guizhou Normal UniversityGuiyang 550025China

On one hand,we study the existence of transcendental entire solutions with finite order of the Fermat type difference *** the other hand,we also investigate the existence and growth of solutions of nonlinear different... 详细信息

关键词： entire solutions differential-difference equations existence finite order

Normalized Solution for p-Kirchhoff Equation with a L2-supercritical Growth

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 414-429页

作者： Zhi-min ren Yong-yi LAN School of Sciences Jimei UniversityXiamen 361005China

In this paper,we investigate the following p-Kirchhoff equation{∫R^(N)|u|^(2)dx=ρ,(a+b)∫RN(|Δu}^(p)+|u|^(p))dx)(-Δpu+|u|^(p-2u)=|u|^(s-2)u+μu,x∈R^(N),where a>0,b≥0,p>0 are constants,constants,p*=N-P/Np is the ... 详细信息

关键词： p-Kirchhoff equation normalized solution mountain-pass lemma

Is the spatial impact of digital financial inclusion on CO_(2) emissions real?A spatial fluctuation spillover perspective

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Geoscience Frontiers 2024年第4期15卷 494-504页

作者： Jianda Wang Kangyin Dong Xiaohang ren School of International Trade and Economics University of International Business and EconomicsBeijing 100029China School of Business Central South UniversityChangsha 410083China

Digital financial inclusion(DFI)has the advantage of promoting information sharing,reducing transaction costs,and providing microloan platforms for small and medium-sized *** has also made outstanding contributions to decreasing CO_(2) ***,the volatility correlation between DFI and CO_(2) emissions is still relatively *** research uses the spatial autoregressive process with conditional heteroscedastic errors(SARspARCH)model to evaluate the spatial fluctuation spillover impacts of DFI on CO_(2) emissions in 284 Chinese cities covering the period 2011-2016 following the IPAT *** results indicate that CO_(2) emissions have significant spatial spillover and volatility *** fitted value of SARspARCH estimation results is more realistic than the SAR and spARCH *** alleviates average CO_(2) emissions in Chinese ***,spatial volatility weakens the negative influence of DFI on average carbon *** study provides insights from which governments can strengthen inter-regional communication and synergistic emission-reduction capabilities,and promote the digitization of the financial sector to achieve carbon neutrality goals.

关键词： SARspARCH model Spatial fluctuation spillover effect CO_(2)emissions Digital financial inclusion(DFI) China

Vertical two-dimensional WS_(2)flakes grown on flexible CNT film for excellent electrochemical performance

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Rare Metals 2024年第1期43卷 164-174页

作者： Qian Gong Jing-Yun Zou Ming ren Si-Qi Zhu Yu-Rong Zhou Li-Ming Zhao Jian Chen Yu-Long Wu Jiang-Tao Di Li-Xing Kang Qing-wen Li School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefei 230026China Key Laboratory of Multifunctional Nanomaterials and Smart Systems Division of Advanced MaterialsSuzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China Jiangsu Key Laboratory of Micro and Nano Heat Fluid Flow Technology and Energy Application School of Physical Science and TechnologySuzhou University of Science and TechnologySuzhou 215009China

Soft electrochemical actuators that can generate mechanical motions in response to electrical stimuli can be used as artificial muscles in microscale *** electrode materials are the key component of the electrochemical actuator because they limit the ion diffusion and accumulation processes and thus affect the deformation in fast response-time and potential engineering ***-dimensional materials,such as one-dimensional(1D)CNT and two-dimensional(2D)vertically stood WS_(2),are great electrode due to their good electrochemical stability and high surface-to-volume ratios,but show limited performances when being used on their own in the actuators because of low reconstruction or low conductivity.A combination of 1D CNT and 2D WS_(2)could form a heterojunction with both high electrochemical activity and great mechanical ***,by depositing highly disordered graphene nanosheets(HDGNs)on CNT films and then WS_(2)on the formed low-dimensional nanocarbon film,a hybrid WS_(2)/HDGN/CNT film was synthesized through a multistep CVD *** grown WS_(2)nanosheets were achieved by taking advantage of HDGNs which limits CNTs ***,the volume expansion caused by the transition from WO_(3)to WS-2can force the vertical growth of WS_(2).This hybrid film shows excellent electrochemical properties,such as high specific capacitance and high rate *** actuators based on the WS_(2)/HDGN/CNT films show good actuating performance,including stability and reconfigurability.

关键词： CNT Graphene Vertically growth WS_(2) Electrochemical actuators

Insight into structural degradation of NCMs under extreme fast charging process

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Rare Metals 2024年第1期43卷 41-50页

作者： Yu Tang Xing-Yu Wang Jin-Can ren Bo-wen Chen Zhi-Yong Huang Wei Wang Ya-Lan Huang Bing-Hao Zhang Si Lan Zhang-Long He Qi Liu Hao He Department of Physics City University of Hong KongHong Kong 999077China Shenzhen Research Institute City University of Hong KongShenzhen 518057China College of Materials Science and Engineering Changsha University of Science&TechnologyChangsha 410114China

Lithium-ion batteries(LIBs)with extreme fast charging(XFC)capability are considered an effective way to alleviate range anxiety for electric vehicle(EV)*** to the high ionic and electronic conductivity of LiNi_(x)Co_(y)Mn_zO_(2)(x+y+z=1,NCM)cathodes,the inevitable Li plating of graphite in NCM|graphite cell is usually identified as a key bottleneck for XFC ***,the capacity decay mechanism of cathode materials under XFC has not been fully *** this work,three typical NCM cathode materials with different Ni fractions were chosen and their electrochemical performances under XFC associated with structural evolution were investigated.A faster capacity decay of NCMs under XFC conditions is observed,especially for Ni-rich ***-situ X-ray diffraction(XRD)reveals that the multiple caxis parameters appear at the high-voltage regions in Nirich NCMs,which is probably triggered by the larger obstruction of Li(de)***,NCMs with moderate Ni fraction also present a similar trend under XFC *** phenomenon is more detrimental to the structural and morphological stability,resulting in a faster capacity decay than that under low current *** work provides new insight into the degradation mechanism of NCMs under XFC conditions,which can promote the development of NCM cathode materials with XFC capability.

关键词： Lithium-ion batteries Ni fraction Extreme fast charging Structural evolution