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Genes & Diseases 2024年第2期11卷 874-889页

作者： Yancheng Lai Xiaole Lu Yankai Liao pei ouyang Hai Wang Xian Zhang Guanglong Huang Songtao Qi Yaomin Li Department of Neurosurgery Institute of Brain DiseaseNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China Laboratory for Precision Neurosurgery Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China

Glioblastoma(GBM)is the most common intrinsic and aggressive primary brain tumor in adults,with a median survival of approximately 15 *** heterogeneity is considered responsible for the treatment resistance and unfavorable ***-mesenchymal transition(PMT)represents GBM malignant progression and recurrence,which might be a breakthrough to understand GBM heterogeneity and overcome treatment *** is a complicated process influenced by crosstalk between GBM and tumor microenvironment,depending on intricate ligand-receptor *** this review,we summarize the autocrine and paracrine pathways in the GBM microenvironment and related ligand-receptor interactions inducing *** also discuss the current therapies targeting the PMT-related autocrine and paracrine ***,this review offers a comprehensive understanding of the failure of GBM-targeted therapy and ideas for future tendencies of GBM treatment.

关键词： Autocrine Glioblastoma Ligand-receptor interaction Microenvironment Paracrine Proneural-mesenchymal transition

口腔放射影像数字化技术在口腔科临床检验工作中的应用效果研究

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影像技术 2024年第2期36卷 20-24页

作者：欧阳佩佩河南护理职业学院河南455000

目的:通过对比实验研究口腔放射影像数字化技术在口腔科临床检验工作中的应用效果。方法:以本职业学院2022年1月-2023年12月治疗的120例患有口腔疾病的学生为研究对象,分别对其实施传统摄片技术检查与口腔放射影像数字化技术检查。在这... 详细信息

目的:通过对比实验研究口腔放射影像数字化技术在口腔科临床检验工作中的应用效果。方法:以本职业学院2022年1月-2023年12月治疗的120例患有口腔疾病的学生为研究对象,分别对其实施传统摄片技术检查与口腔放射影像数字化技术检查。在这一前提下,对比两种检查方法诊断各类口腔科疾病的准确率。结果:与传统摄片技术检查相比,口腔放射影像数字化技术检查诊断牙体病、牙周病、颌骨疾病的准确率均处于较高水平(P<0.05)。结论:针对口腔科疾病患者进行口腔放射影像数字化技术检查,可准确诊断牙体病、牙周病、颌骨疾病等各类口腔科疾病。

关键词：口腔疾病口腔放射影像数字化技术临床检验

Effect of Nano-TiO_2 Addition on the Hydration and Hardening Process of Sulphoaluminate Cement

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Journal of Wuhan University of Technology(Materials Science) 2015年第4期30卷 768-773页

作者：马保国李海南 MEI Junpeng ouyang pei State Key Laboratory of Silicate Materials for Architectures Wuhan University of Technology

The influences of nano-TiO2 on the setting time, hydration process, hydration products and morphology of sulphoaluminate cement were studied by Vicar apparatus, isothermal calorimetry, X-ray diffraction （XRD）, thermal analysis and scanning electron microscopy （SEM）. The experimental results show that the incorporation of nano-TiO2 can obviously promote the setting and hardening process of sulphoaluminate cement, and shorten the interval between the initial and final setting time, the hydration induction period of sulphoaluminate cement is significantly shortened and the acceleration period begins immediately, but the hydration exothermic rate at hydration stationary phase is not obviously impacted. The nano-TiO2 additives have influence on the formation rate and degree of crystallinity, but do not affect the type of hydration process. The structure of hydration products is compact at middle age, but their content and microstructure do not change

关键词： sulphoaluminate cement nano-TiO2 hydration process hydration products

Analytical modelling of the mechanical damage of soil induced by lightning strikes capturing electro-thermal,thermo-osmotic,and electro-osmotic effects

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Journal of Mountain Science 2022年第7期19卷 2027-2043页

作者： RAO Ping-ping ouyang pei-hao NIMBALKAR Sanjay CHEN Qing-sheng WU Zhi-lin CUI Ji-fei Department of Civil Engineering University of Shanghai for Science and TechnologyShanghai200093China School of Civil and Environmental Engineering University of Technology Sydney15 BroadwayUltimoNSW2007Australia Technology Research Center of Ecological Road Engineering Hubei University of TechnologyWuhan430068China

This article presents a mathematical model for simulating the mechanical behaviour of lightning strikes and analysing the resulting damage to the *** article focuses on the electro-thermal effect and seepage caused by lightning strikes in ***,a numerical model based on the conservation laws of momentum,mass and energy is developed for soil subjected to lightning *** to field observations and theoretical calculations are used to demonstrate the efficacy and accuracy of numerical *** findings demonstrate that lightning strikes can cause soils to experience both seepage force and heat *** the calculative condition of this article:by increasing the intrinsic permeability of the soil,k_(p)(≥10^(-10)m^(2)),the seepage force can be effectively reduced,hence reducing the risk of lightning strikes;improving the electrical conductivity of the soil β(≥10^(-1) S/m^(2))and lowering its thermal expansion coefficient(≤10^(-6)K^(-1))can greatly reduce the damage caused by lightning strikes to the *** preceding investigations demonstrate that the suggested model is capable of evaluating mechanical damage caused by lightning in the soil,and the findings contribute to a better understanding of soil mechanical response to lightning strikes.

关键词： Lightning strikes Analytical modelling Soil damage Electro-thermo-osmotic effect Conservation laws

A harmonic-wave bio-thermal method for continuous monitoring skin thermal conductivity and capillary perfusion rate

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Nano Research 2024年第5期17卷 4420-4427页

作者： Yuxin ouyang Jie Lin Jiajing pei Rui Sui Di Liu Yanhui Feng Lin Qiu School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China Beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Department of Chemistry Tsinghua UniversityBeijing 100084China Institute of Analysis and Testing Beijing Academy of Science and TechnologyBeijing 100089China

The revelation of thermal energy exchange mechanism of human body is challenging yet worthwhile,because it can clearly explain the changes in human symptoms and health ***,the heat transfer of the skin is significant because the skin is the foremost organ for the energy exchange between the human body and the *** order to diagnose the physiological conditions of human skin without causing any damage,it is necessary to use a non-invasive measurement technique by means of a conformal flexible *** harmonic method can minimize the thermal-induced injury to the skin due to its low heat generating properties.A novel type of computational theory assessing skin thermal conductivity,blood perfusion rate of capillaries in the dermis,and superficial subcutaneous tissues was formed by combining the multi-medium thermal diffusion model and the bio-thermal model(Pennes equation).The skins of the hand back of six healthy subjects were *** was found that the results revealed no consistent changes in thermal conductivity were observed across genders and *** measured blood perfusion rates were within the range of human capillary *** was found that female subjects had a higher perfusion rate range(0.0058-0.0061 s^(-1))than male subjects(0.0032-0.0049 s^(-1)),which is consistent with invasive medical studies about the gender difference in blood flow rates and stimulated effects in relaxation situations.

关键词： thermal conductivity blood perfusion rate harmonic method Pennes equation

Geological Context of the SLIM Landing Site

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Journal of Earth Science 2024年第2期35卷 708-711页

作者： Yichen Wang Zhiyong Xiao pei Ma Hanxing ouyang Wei Cao Planetary Environmental and Astrobiological Research Laboratory School of Atmospheric SciencesSun Yat-sen UniversityZhuhai 519000China Chinese Academy of Sciences Center for Excellence in Comparative Planetology Hefei 230026China Planetary Science Institute School of Earth SciencesChina University of GeoscienceWuhan 430074China

INTRODUCTION Japan’s first successful lunar landing mission,Smart Lander for Investigating Moon(SLIM),was landed on the Moon on January 19th,*** made a precise landing within 100 m of the targeted landing zone(central coordinates 13.316°S,25.251°E),which is located around the Shioli crater(D=270 m,central coordinates as 13.33°S,25.23°E)in the southwestern ejecta of the Theophilus crater(D=98.6 km,central coordinates as 11.45°S,26.28°E).

关键词： southwestern coordinates SLIM

CO_2 processes in an alpine grassland ecosystem on the Tibetan Plateau

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Journal of Geographical Sciences 2003年第4期13卷 429-437页

作者： pei Zhiyong, ouyang Hua, ZHOU Caiping, XU Xingliang(Inst. of Geographic Sciences and Natural Resources Research, CAS, Beijing 100101, China) Inst. of Geographic Sciences and Natural Resources Research CAS Beijing China

In this paper, the CO2 concentrations profile from 1.5 m depth in soil to 32 m height in atmosphere were measured from July 2000 to July 2001 in an alpine grassland ecosystem located in the permafrost area on the Tibetan Plateau, which revealed that CO2 concentrations varied greatly during this study period. Mean concentrations during the whole experiment in the atmosphere were absolutely lower than the CO2 concentrations in soil, which resulted in CO2 emissions from the alpine steppe soil to the atmosphere. The highest CO2 concentration was found at a depth of 1.5 m in soil while the lowest CO2 concentration occurred in the atmosphere. Mean CO2 concentrations in soil generally increased with depth. This was the compositive influence of the increasing soil moistures and decreasing soil pH, which induced the increasing biological activities with depth. Temporally, the CO2 concentrations at different layers in air remained a more steady state because of the atmospheric turbulent milking. During the seasonal variations, CO2 concentrations at surface soil interface showed symmetrical patterns, with the lowest accumulation of CO2 occurring in the late winter and the highest CO2 concentration in the growing seasons.

关键词： CO2 soil atmosphere alpine grassland Tibetan Plateau

Fluxes of CO_2,CH_4 and N_2O from alpine grassland in the Tibetan Plateau

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Journal of Geographical Sciences 2003年第1期13卷 27-34页

作者： pei Zhiyong,ouyang Hua,ZHOU Caiping,XU Xingliang(Inst. of Geographic Science s and Natural Resources Research, CAS, Beijing 100101, China) Inst. of Geographic Sciences and Natural Resources Research CAS Beijing China

Using stat ic chamber technique, fluxes of CO 2 , CH 4 and N 2 O were measured in the alpine grassland area from July 2000 to July 2001, d eterminations of mean fluxes showed that CO 2 and N 2 O were gene rally released from the soil, while the alpine grassland accounted for a weak CH 4 sink. Fluxes of CO 2 , CH 4 and N 2 O ranged widely. The highest CO 2 emission occurred in August, whereas a lmost 90% of the whole year emission occurred in the growing season. But the variations of CH 4 and N 2 O fluxes did not show any clear patterns over the one-year-experim ent. During a daily variation, the maximum CO 2 emission occurred at 16:00, and then decreased to the minimum emi ssion in the early morning. Daily pattern analyses indicated that the variation in CO 2 fluxes was positively related to air temperatures (R 2 =0.73) and soil temperatures at a depth of 5 cm (R 2 =0.86), whereas daily variations in CH 4 and N 2 O fluxes were poorly explained by soil temperatures and climatic va riables. CO 2 emissions in this area were much lower than other grasslands in plain areas .

关键词： CO 2 , CH 4 and N 2 O flux alpine grassland Tibetan Plateau

颅咽管瘤相关下丘脑性肥胖患儿饮食运动管理方案的构建

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护理学杂志 2024年第17期39卷 45-49页

作者：王为杰史蕾邓瑛瑛陈美佳梁清钊欧阳配黄佳颖张静南方医科大学护理学院南方医科大学南方医院神经外科南方医科大学南方医院呼吸内科

目的构建颅咽管瘤相关下丘脑性肥胖患儿饮食运动管理方案，为临床实践提供参考。方法以健康行为改变整合理论为指导，通过文献循证、半结构式访谈，形成颅咽管瘤相关下丘脑性肥胖患儿饮食运动管理方案初稿；运用德尔菲法，遴选19名专... 详细信息

目的构建颅咽管瘤相关下丘脑性肥胖患儿饮食运动管理方案，为临床实践提供参考。方法以健康行为改变整合理论为指导，通过文献循证、半结构式访谈，形成颅咽管瘤相关下丘脑性肥胖患儿饮食运动管理方案初稿；运用德尔菲法，遴选19名专家对方案进行2轮函询，完善并确定最终方案。结果 2轮专家函询问卷回收率分别为90.48%、100%,专家权威系数分别为0.89、0.90;第2轮函询中，各指标重要性变异系数0.06～0.19,肯德尔和谐系数0.101(P<0.05),各指标可行性变异系数0.10～0.23,肯德尔和谐系数0.122(P<0.05);最终形成包含4个一级指标、18个二级指标、44个三级指标的颅咽管瘤相关下丘脑性肥胖患儿饮食运动管理方案。结论颅咽管瘤相关下丘脑性肥胖患儿饮食运动管理方案具有较好的专家认可度和可行性，可进一步开展临床验证研究。

关键词：儿童颅咽管瘤下丘脑性肥胖健康行为改变整合理论营养运动证据总结德尔菲法

Phonon transport properties of Janus Pb_(2)XAs(X=P,Sb,and Bi)monolayers:A DFT study

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Chinese Physics B 2024年第4期33卷 71-76页

作者：耿嘉鑫张培汤准韵欧阳滔 School of Physics and Optoelectronics and Hunan Key Laboratory for Micro-Nano Energy Materials and Device Xiangtan UniversityXiangtan 411105China Hunan Provincial Key Laboratory of Intelligent Sensors and Advanced Sensor Materials School of Physics and ElectronicsHunan University of Science and TechnologyXiangtan 411201China

Grasping the underlying mechanisms behind the low lattice thermal conductivity of materials is essential for the efficient design and development of high-performance thermoelectric materials and thermal barrier coating *** this paper,we present a first-principles calculations of the phonon transport properties of Janus Pb_(2)PAs and Pb_(2)SbAs *** materials possess low lattice thermal conductivity,at least two orders of magnitude lower than graphene and *** room temperature thermal conductivity of Pb_(2)SbAs(0.91 W/m K)is only a quarter of that of Pb_(2)PAs(3.88 W/m K).We analyze in depth the bonding,lattice dynamics,and phonon mode level information of these ***,it is determined that the synergistic effect of low group velocity due to weak bonding and strong phonon anharmonicity is the fundamental cause of the intrinsic low thermal conductivity in these Janus *** regular residual analysis further indicates that the four-phonon processes are limited in Pb_(2)PAs and Pb_(2)SbAs,and the three-phonon scattering is sufficient to describe their *** this study,the thermal transport properties of Janus Pb_(2)PAs and Pb_(2)SbAs monolayers are illuminated based on fundamental physical mechanisms,and the low lattice thermal conductivity endows them with the potential applications in the field of thermal barriers and thermoelectrics.

关键词： lattice thermal conductivity weak bonding phonon anharmonicity first principles calculations