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Outcomes of early hospital readmission after kidney transplantation: Perspectives from a Canadian transplant centre

World Journal of Transplantation 2023年第6期13卷 357-367页

作者： Olusegun Famure Esther DKim Yanhong Li Johnny WHuang Roman Zyla Magdalene Au pei xuanchen Heebah Sultan Monika Ashwin Michelle Minkovich S Joseph Kim Department of Nephrology Kidney TransplantToronto General HospitalToronto M5G 2N2OntarioCanada Department of Kidney Transplant Toronto General HospitalToronto M5G 2N2OntarioCanada

BACKGROUND Early hospital readmissions(EHRs)after kidney transplantation range in incidence from 18%-47%and are important and substantial healthcare quality *** can adversely impact clinical outcomes such as graft function and patient mortality as well as healthcare *** have been extensively studied in American healthcare systems,but these associations have not been explored within a Canadian *** to significant differences in the delivery of healthcare and patient outcomes,results from American studies cannot be readily applicable to Canadian populations.A better understanding of EHR can facilitate improved discharge planning and long-term outpatient management post kidney *** To explore the burden of EHR on kidney transplant recipients(KTRs)and the Canadian healthcare system in a large transplant *** This single centre cohort study included 1564 KTRs recruited from January 1,2009 to December 31,2017,with a 1-year *** defined EHR as hospitalizations within 30 d or 90 d of transplant discharge,excluding elective *** Cox and linear regression models were used to examine EHR,late hospital readmissions(defined as hospitalizations within 31-365 d for 30-d EHR and within 91-365 d for 90-d EHR),and outcomes including graft function and patient *** In this study,307(22.4%)and 394(29.6%)KTRs had 30-d and 90-d EHRs,*** such as having previous cases of rejection,being transplanted in more recent years,having a longer duration of dialysis pretransplant,and having an expanded criteria donor were associated with EHR *** cumulative probability of death censored graft failure,as well as total graft failure,was higher among the 90-d EHR group as compared to patients with no *** multivariable models found no significant association between EHR and patient mortality,patients with EHR were at an increased risk of late hospital readmissions,poorer kidney fun

关键词： Kidney Transplantation Early hospital readmissions Incidence and trends Post-transplant outcomes

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