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Numerical insight into heat transfer enhancement by granules inner-migration in a moving bed:A performance comparison between slanted-stick and plow-shaped agitator

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Particuology 2024年第6期89卷 109-116页

作者： Binfan Jiang Hao pei Dehong Xia Haiyang Wang School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China Shunde Graduate School of University of Science and Technology Beijing Guangdong 528399China Jianlong Group&USTB Joint Laboratory Beijing 100083China

Waste heat recovery of high-temperature granules is one of the most promising sustainable energy supply and carbon reduction ways for industry.A moving bed indirect heat exchanger(MBIHE)with inner-migration was proposed for granular heat *** migration and the enhanced heat transfer induced by two types of agitators(i.e.,agitator with slanted stick A_(s)and with plow-shaped surface A_(p))in the MBIHE are analyzed based on DEM coupled with *** to the effective agitation,the average heat transfer coefficient in the granule side is enhanced to∼3 times compared to that without *** heat recovery efficiency in the moving bed reached more than 70%with the agitations of either A_(s)or A_(p).The heat efficiency of A_(s)is∼7%higher than that of A_(p),but with at least 60%greater rotational *** ensure reliable agitation,the A_(p)is suggested to be adopted in the MBIHE to induce granule migration.

关键词： Waste heat recovery High-temperature granule Granule migration Heat transfer enhancement Industry energy saving

Validation and performance of three scoring systems for predicting primary non-function and early allograft failure after liver transplantation

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Hepatobiliary & Pancreatic diseases International 2024年第5期23卷 463-471页

作者： Yu Nie jin-Bo Huang Shu-Jiao He Hua-di Chen Jun-Jun Jia jing-jing Li Xiao-Shun He Qiang Zhao General Surgery Center Department of Hepatobiliary Surgery IIResearch Center for Artificial Organ and Tissue EngineeringGuangzhou Clinical Research and Transformation Center for Artificial LiverInstitute of Regenerative MedicineZhujiang HospitalSouthern Medical UniversityGuangzhou 510515China Organ Transplant Center the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology Guangzhou 510080China Guangdong Provincial International Cooperation Base of Science and Technology Guangzhou 510080China division of Hepatobiliary Pancreatic Surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Background: Primary non-function(PNF) and early allograft failure(EAF) after liver transplantation(LT) seriously affect patient outcomes. In clinical practice, effective prognostic tools for early identifying recipients at high risk of PNF and EAF were urgently needed. Recently, the Model for Early Allograft Function(MEAF), PNF score by King's College(King-PNF) and Balance-and-Risk-Lactate(BAR-Lac) score were developed to assess the risks of PNF and EAF. This study aimed to externally validate and compare the prognostic performance of these three scores for predicting PNF and EAF. Methods: A retrospective study included 720 patients with primary LT between January 2015 and December 2020. MEAF, King-PNF and BAR-Lac scores were compared using receiver operating characteristic(ROC) and the net reclassification improvement(NRI) and integrated discrimination improvement(Idi) analyses. Results: Of all 720 patients, 28(3.9%) developed PNF and 67(9.3%) developed EAF in 3 months. The overall early allograft dysfunction(EAD) rate was 39.0%. The 3-month patient mortality was 8.6% while 1-year graft-failure-free survival was 89.2%. The median MEAF, King-PNF and BAR-Lac scores were 5.0(3.5–6.3),-2.1(-2.6 to-1.2), and 5.0(2.0–11.0), respectively. For predicting PNF, MEAF and King-PNF scores had excellent area under curves(AUCs) of 0.872 and 0.891, superior to BAR-Lac(AUC = 0.830). The NRI and Idi analyses confirmed that King-PNF score had the best performance in predicting PNF while MEAF served as a better predictor of EAD. The EAF risk curve and 1-year graft-failure-free survival curve showed that King-PNF was superior to MEAF and BAR-Lac scores for stratifying the risk of EAF. Conclusions: MEAF, King-PNF and BAR-Lac were validated as practical and effective risk assessment tools of PNF. King-PNF score outperformed MEAF and BAR-Lac in predicting PNF and EAF within 6 months. BAR-Lac score had a huge advantage in the prediction for PNF without post-transplant variables. Proper use

关键词： Primary non-function Early allograft failure Risk predicting model Liver transplantation

A Coordinate-Free Approach to the Design of Generalized Griffis-Duffy Platforms

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Chinese Journal of Mechanical Engineering 2024年第3期37卷 95-103页

作者： Chengwei Shen Xu pei Lubin Hang jingjun Yu College of Optical Mechanical and Electrical EngineeringZhejiang A&F UniversityHangzhou 311300China School of Mechanical Engineering and Automation Beihang UniversityBeijing 100191China School of Mechanical and Automotive Engineering Shanghai University of Engineering ScienceShanghai 201620China

Architectural singularity belongs to the Type II singularity,in which a parallel manipulator(PM)gains one or more degrees of freedom and becomes *** remaining permanently in a singularity are beneficial for linearto-rotary motion ***-Duffy(GD)platform is a mobile structure admitting a Bricard *** this paper,we present a coordinate-free approach to the design of generalized GD platforms,which consists in determining the shape and attachment of both the moving platform and the fixed *** generalized GD platform is treated as a combination of six coaxial single-loop mechanisms under the same *** to the inversion,hidden in the geometric structure of these single-loop mechanisms,the mapping from a line to a circle establishes the geometric transformation between the fixed base and the moving platform based on the center of inversion,and describes the shape and attachment of the generalized GD ***,the center of inversion not only identifies the location of rotation axis,but also affects the shape of the platform mechanism.A graphical construction of generalized GD platforms using inversion,proposed in the paper,provides geometrically feasible solutions of the manipulator design for the requirement of the location of rotation axis.

关键词： Generalized Griffis-Duffy platforms Self-motion Inversion Coordinate-free determination Manipulator design

Medical dilemma:Programmed death 1 blockade(sintilimab)therapy in patients suffering from tumours combined with psoriasis

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World Journal of Cardiology 2024年第9期16卷 546-549页

作者： di jin Yu-Wei Wang Zhi-Min Lin Chen Li Ming Li Department of Rheumatology Weifang People’s HospitalWeifang 261000Shandong ProvinceChina Department of Cardiology Yidu Central Hospital of WeifangWeifang 261000Shandong ProvinceChina Third Affiliated Hospital Beijing University of Chinese MedicineBeijing 100020China Department of Rheumatology Fangshan HospitalBeijing University of Chinese MedicineBeijing 102400China

Tumour immunotherapy represented by immune checkpoint inhibitors(ICIs)has greatly improved the overall prognosis of patients with malignant tumours,and is regarded as an important breakthrough in the field of medicine in recent *** have gradually become the core of tumour therapy and are increasingly used in the *** order to achieve early clinical prediction and management of immune-related adverse events(irAEs),it is still necessary to perform further research on the mechanisms,risk factors,and predictors of irAE occurrence in the *** et al describe the consultation of a patient with advanced gastric cancer combined with chronic plaque *** case provides an important reference for the use of programmed cell death protein-1(PD-1)inhibitors in patients of tumours combined with chronic plaque *** case also highlights that screening of high-risk groups for irAEs is critical before applying PD-1 inhibitors to patients with chronic psoriasis combined with ***-1 inhibitors are new and potent antineoplastic agents that can cause serious immunerelated adverse events such as toxic epidermal necrolysis release and *** are the first-line agents for *** incidence of rheumatic irAEs may be higher in reality,which will inevitably become a new challenge for rheumatologists and dermatologists.

关键词： Immune checkpoint inhibitors Tumor immunotherapy Immune-related adverse events Cytokine release syndrome Psoriasis

Long-term Evolution of Solar Activity and Prediction of the Following Solar Cycles

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Research in Astronomy and Astrophysics 2024年第3期24卷 194-204页

作者： pei-Xin Luo Bao-Lin Tan National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China

Solar activities have a great impact on modern high-tech systems,such as human aerospace activities,satellite communication and navigation,deep space exploration,and related scientific ***,studying the long-term evolution trend of solar activity and accurately predicting the future solar cycles are highly *** on the wavelet transform and empirical function fitting of the longest recorded data of the annual average relative sunspot number(ASN)series of 323 yr to date,this work decisively verifies the existence of the solar century cycles and confirms that its length is about 104.0 yr,and the magnitude has a slightly increasing trend on the timescale of several hundred *** on this long-term evolutionary trend,we predict solar cycles 25 and26 by using phase similar prediction *** for solar cycle 25,its maximum ASN will be about146.7±33.40,obviously stronger than solar cycle *** peak year will occur approximately in 2024,and the period will be about 11±1 *** for solar cycle 26,it will start around 2030,and reach its maximum between2035 and 2036,with maximum ASN of about 133.0±3.200,and period of about 10 yr.

关键词： Sun activity-Sun evolution-(Sun) sunspots-methods data analysis

Permanent lining castable with low bulk density and thermal conductivity:bauxite castable for tundish obtained by adding pearlescent sand

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Journal of Iron and Steel Research International 2024年第3期31卷 634-646页

作者： Yi Wang Jian Yang Bao Wang Hai-jun Zhang Juan Han pei-yan pei Wen-long Lv Jian-an Zhou The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081HubeiChina Wuhan Research Institute of Metallurgical Construction MCCWuhan 430081HubeiChina

The low thermal conductivity and light mass of castables for tundish permanent linings are crucial for minimizing the heat loss of molten *** consideration of the low bulk density and thermal conductivity of pearlescent sand,the thermal insulation performance of castables was attempted to be improved by adding pearlescent *** sand was modified to prevent the strength of its porous structure from *** modification mechanism of pearlescent sand and the effect of pearlescent sand on the performance of bauxite castables were *** results suggested that the addition of the modified pearlescent sand significantly raised the apparent porosity and decreased the bulk density of bauxite *** 1000℃,the bulk density of more than 60%of the modified pearlescent sand-bauxite castable was only 2.03 g/cm^(3).The mechanical properties and thermal shock resistance of the modified pearlescent sand-bauxite castable were inferior to those of conventional bauxite castable but were adequate to meet the use conditions of casta-bles for tundish permanent *** high temperatures of 200-800℃,the thermal conductivity of more than 60%of the modified pearlescent sand-bauxite castable was smaller than that of conventional bauxite *** addition of the modified pearlescent sand can greatly reduce the thermal conductivity and bulk density of bauxite castable.

关键词： Pearlescent sand-Hydrophobic modification Bauxite castable Thermal insulation performance Mechanical property

Exponential Synchronization of Delayed Stochastic Complex Dynamical Networks via Hybrid Impulsive Control

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IEEE/CAA Journal of Automatica Sinica 2024年第3期11卷 785-787页

作者： Yao Cui pei Cheng Xiaohua Ge the School of Mathematic Science Anhui UniversityHefei 230601China IEEE the School of Science Computing and Engineering TechnologiesSwinburne University of TechnologyMelbourne VIC 3122Australia

Dear Editor,This letter addresses the synchronization problem of a class of delayed stochastic complex dynamical networks consisting of multiple drive and response *** aim is to achieve mean square exponential synchronization for the drive-response nodes despite the simultaneous presence of time delays and stochastic noises in node dynamics.

关键词： dynamics stochastic letter

Spectrally resolved Franson interference

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Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 11-17页

作者： Rui-Bo jin Zi-Qi Zeng Dan Xu Chen-Zhi Yuan Bai-Hong Li You Wang Ryosuke Shimizu Masahiro Takeoka Mikio Fujiwara Masahide Sasaki pei-Xiang Lu Hubei Key Laboratory of Optical Information and Pattern Recognition Wuhan Institute of TechnologyWuhan 430205China School of Physics and Information Science Shaanxi University of Science and TechnologyXi'an 710021China Southwest Institute of Technical Physics Chengdu 610041China Graduate School of Informatics and Engineering University of Electro-CommunicationsTokyo 182-8585Japan Department of Electronics and Electrical Engineering Keio UniversityKanagawa 223-8522Japan National Institute of Information and Communications Technology Tokyo 184-8795Japan

Franson interference can be used to test the nonlocal features of energy-time entanglement and has become a standard in quantum ***,most of the previous Franson interference experiments were demonstrated in the time domain,and the spectral properties of Franson interference have not been fully ***,we theoretically and experimentally demonstrate spectrally resolved Franson interference using biphotons with different correlations,including positive correlation,negative correlation,and *** is found that the joint spectral intensities of the biphotons can be modulated along both the signal and idler directions,which has potential applications in generating high-dimensional frequency entanglement and time-frequency grid *** work may provide a new perspective for understanding the spectral-temporal properties of the Franson interferometer.

关键词： resolved correlation spectral

Tuning mechanical behaviors of highly entangled hydrogels with the random distribution of mobile entanglements

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Applied Mathematics and Mechanics(English Edition) 2024年第2期45卷 277-294页

作者： jinlong LIU di LU Bin CHEN Department of Engineering Mechanics Zhejiang UniversityHangzhou 310027China Beijing System Design Institute of Electro-Mechanic Engineering Beijing 100854China Intelligent Robotic Research Center Zhejiang LaboratoryHangzhou 310027China Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province Hangzhou 311100China

Highly entangled hydrogels exhibit excellent mechanical properties,including high toughness,high stretchability,and low *** considering the evolution of randomly distributed entanglements within the polymer network upon mechanical stretches,we develop a constitutive theory to describe the large stretch behaviors of these *** the theory,we utilize a representative volume element(RVE)in the shape of a cube,within which there exists an averaged chain segment along each edge and a mobile entanglement at each *** employing an explicit method,we decouple the elasticity of the hydrogels from the sliding motion of their entanglements,and derive the stress-stretch relations for these *** present theoretical analysis is in agreement with experiment,and highlights the significant influence of the entanglement distribution within the hydrogels on their *** also implement the present developed constitutive theory into a commercial finite element software,and the subsequent simulations demonstrate that the exact distribution of entanglements strongly affects the mechanical behaviors of the structures of these ***,the present theory provides valuable insights into the deformation mechanism of highly entangled hydrogels,and can aid in the design of these hydrogels with enhanced performance.

关键词： highly entangled hydrogel constitutive theory entanglement gamma distribution