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Extracting a seizure intensity index from one-channel EEG signal using bispectral and detrended fluctuation analysis

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Journal of Biomedical Science and Engineering 2010年第3期3卷 253-261页

作者： pegah tayaranian hosseini Reza Shalbaf Ali Motie Nasrabadi 不详

Epilepsy is a medical condition that produces seizures affecting a variety of mental and physical functions. Seizures can last from a few seconds to a few minutes. They can have many symptoms, from convulsions and loss of consciousness to blank staring, lip smacking, or jerking movements of arms and legs. If early warning signals of an upcoming seizure (diagnosis of preictal period) are detected, proper treatment can be applied to the patient to help prevent the seizure. In this research, an epileptic disorder has been divided into three subsets: Normal, Preictal (just before the seizure), and Ictal (during seizure). By using Detrended Fluctuation Analysis (DFA), Bispectral Analysis (BIS), and Standard Deviation (SD) three features from single-channel EEG signals have been derived in the foresaid groups. A fuzzy classifier is used to separate the three groups which can successfully separate them with a separation degree of 100% and further a fuzzy inference engine is used to extract a Seizure Intensity Index (SII) from the Electroencephalogram (EEG) signals of the three different states. One can apparently see the distinction of SII amounts between the three states. It is more important when one remembers that these results are just from single-channel EEG signal.

关键词： Epilepsy Fuzzy Inference Engine Bispectrum Detrended Fluctuation Analysis

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Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2015年第4期6卷 156-171页

作者： pegah hosseini-Carroll Monica Mutyala Abhishek Seth Shaheen Nageeb Demiana Soliman Moheb Boktor Ankur Sheth Jonathon Chapman James Morris Paul Jordan Kenneth Manas Felix Becker Jonathan Steven Alexander Department of Medicine Section of Gastroenterology and Hepatology Louisiana State University Health Sciences Center Department of Molecular and Cellular Physiology Louisiana State University Health Sciences Center Digestive Health Center of Louisiana Department of General and Visceral Surgery

Inflammatory bowel diseases(IBD) are chronic idiopathic inflammatory conditions characterized by relapsing and remitting episodes of inflammation which can affect several different regions of the gastrointestinal tract, but also shows extra-intestinal manifestations. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While IBD therapy has improved dramatically with enhanced surveillance and more abundant and powerful treatment options, IBD disease can have important effects on pregnancy and presents several challenges for maintaining optimal outcomes for mothers with IBD and the developing fetus/neonate. Women with IBD, the medical team treating them(both gastroenterologists and obstetricians/gynecologists) must often make highly complicated choices regarding conception, pregnancy, and post-natal care(particularly breastfeeding) related to their choice of treatment options at different phases of pregnancy as well as post-partum. This current review discusses current concerns and recommendations for pregnancy duringIBD and is intended for gastroenterologists, general practitioners and IBD patients intending to become,(or already) pregnant, and their families. We have addressed patterns of IBD inheritance, effects of IBD on fertility and conception(in both men and women), the effects of IBD disease activity on maintenance of pregnancy and outcomes, risks of diagnostic procedures during pregnancy and potential risks and complications associated with different classes of IBD therapeutics. We also have evaluated the clinical experience using "top-down" care with biologics, which is currently the standard care at our institution. Post-partum care and breastfeeding recommendations are also addressed.

关键词： Inflammatory bowel diseases Pregnancy Biologics Br

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