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Physico-chemical characterization of acid base disorders in patients with COVID-19:A cohort study

World Journal of Nephrology 2024年第2期13卷 16-23页

作者： Sergio Pinto de Souza Juliana R Caldas Marcelo Barreto Lopes Marcelo Augusto Duarte Silveira Fernanda Oliveira Coelho Igor Oliveira Queiroz pedro domingues cury Rogério da Hora Passos Department of Nephrology Hospital São RafaelSalvadorBA 41253190Brazil Department of Nephrology D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Faculty of Medicine Escola Bahiana de Medicina e Saúde Pública-EBMSPSalvadorBA 40290000Brazil Department of Intensive Care D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Hospital São Rafael D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Department of Intensive Care Unit Hospital Israelita Albert EinsteinSao PauloSP 05652900Brazil

BACKGROUND Acid-base imbalance has been poorly described in patients with coronavirus disease 2019(COVID-19).Study by the quantitative acid-base approach may be able to account for minor changes in ion distribution that may have been over-looked using traditional acid-base analysis *** a cohort of critically ill COVID-19 patients,we looked for an association between metabolic acidosis surrogates and worse clinical outcomes,such as mortality,renal dialysis,and length of hospital *** To describe the acid-base disorders of critically ill COVID-19 patients using Stewart’s approach,associating its variables with poor *** This study pertained to a retrospective cohort comprised of adult patients who experienced an intensive care unit stay exceeding 4 days and who were diagnosed with severe acute respiratory syndrome coronavirus 2 infection through a positive polymerase chain reaction analysis of a nasal swab and typical pulmonary involvement observed in chest computed tomography *** and clinical data were obtained from electronic *** variables were compared using Fisher’s exact *** data were presented as median and interquartile *** Mann-Whitney U test was used for *** In total,211 patients were *** mortality rate was 13.7%.Overall,149 patients(70.6%)presented with alkalosis,28 patients(13.3%)had acidosis,and the remaining 34 patients(16.2%)had a normal arterial pondus *** those presenting with acidosis,most had a low apparent strong ion difference(SID)(20 patients,9.5%).Within the group with alkalosis,128 patients(61.0%)had respiratory *** non-survivors were older,had more comorbidities,and had higher Charlson’s and simplified acute physiology score *** did not find severe acid-base imbalance in this *** analyzed Stewart’s variables(effective SID,apparent SID,and strong ion gap and the effect of albumin,lactate,phosphorus,and chloride)were not d

关键词： COVID-19 Physicochemical approach Acid-base status Critically ill patients Acute respiratory syndrome

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Pleistocene Birds of Gruta da Furninha （Peniche-Portugal）： A Paleontological and Paleoenvironmental Aproach

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Journal of Environmental Science and Engineering(A) 2017年第10期6卷 502-509页

作者： Silverio domingues Figueiredo pedro Proenga Cunha Femanda Sousa Telmo Pereira Americo Rosa Polytechnic Institute of Tomar Quinta do Contador Estrada da Serra 2300-313 Tomar Portugal Portuguese Center of Geo-History and Prehistory Largo de Sao Caetano Golega 2150-265 Portugal Geosciences Center--Univ. of Coimbra Rua Silvio Lima Univ. Coimbra Coimbra 3030-790 Portugal MARE--Marine and Environmental Sciences Centre Department of Earth Sciences Coimbra University Rua Silvio LimaCoimbra 3030- 790 Portugal ICArEHB--Interdisciplinary Center for Archaeology and Evolution of Human Behaviour Human and Social Sciencies Faculty University of Algarve Campus de Gambelas 8005-139 Faro Portugal

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Inheritance of AFLP markers and genetic linkage analysis in two full-sib families of the marine shrimp Litopenaeus vannamei(Crustacea,Decapoda)

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Advances in Bioscience and Biotechnology 2014年第3期5卷 273-281页

作者： Michele Mantovani Goncalves Luciana Correia de Almeida Regitano Cosme Damiao Cruz Caio Cesio Salgado Patricia domingues de Freitas Joao Luis Rocha Ana Karina Guerrelhas Teixeira pedro Manoel Galetti-Junior Departamento de Genetica e Evolucao Universidade Federal de Sao CarlosSao CarlosBrasil Embrapa Pecuaria Sudeste Sao CarlosSPBrasil Departamento de Biologia Geral Universidade Federal de VicosaVicosaBrasil Genearch Aquacultura Ltda Rua Pedro Zuca s/nPraia de PititingaRio do FogoRNBrasil

The cultivation of the marine species of shrimp Litopenaeus vannamei has emerged as one of the segments that best develop in the Brazilian aquaculture, representing the agribusiness that grew the most in recent years. Regarding the economic importance of the farming of this species in Brazil, further studies on genetic improvement were conducted. A F2 segregating population consisting of 192 samples for each G1 and G2 families, from crossing inbred lines was used for the studies performed in the present work. The genetic linkage analysis was based on polymorphic markers derived from nine AFLP (Amplified Fragment Length Polymorphism) primers. Fourteen genetic linkage groups including 103 segregating polymorphic markers were constructed covering350 cMfor G1 and four genetic linkage groups including 59 markers were constructed covering300 cMfor G2. Simple marker analyses were performed among individuals evaluated phenotypically, finding markers linked to genes that may be potentially important and useful to assess characteristics of economic importance for traits related to weight and the disease IMN (idiopathic muscle necrosis). The statistical model including markers explained major proportion of phenotypic characteristic weight in relation to disease incidence IMN.

关键词： Shrimp Litopenaeus vannamei AFLP Genetic Linkage Groups

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Development of Standard Reagents for Avian Influenza Virus Subtypes Diagnosis

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Journal of Agricultural Science and Technology(A) 2019年第1期9卷 26-37页

作者： Maria Angela Orsi Soraya Cecilia Albieri Camillo Eluana Carolina Fortunato Christian Steffe domingues Dilmara Reischak Margarida Maria Hoppner Zaroni Tania Rosária Pereira Freitas Terra A.Jenson Janice C.Pedersen Agriculture and Livestock National Laboratory-Sao Paulo LANAGRO-SPMinistry of AgricultureLivestock and SupplayMAPACampinasSao PauloBrazil Agriculture and Livestock National Laboratory-Minas Gerais LANAGRO-MGMinistry of AgricultureLivestock and SupplayMAPAPedro LeopoldoMinas GeraisBrazil U.S.Department of Agriculture Animal and Plant Health Inspection ServiceVeterinary ServicesNational Veterinary Services Laboratories(NVSL)AmesIAUSA

Avian influenza(AI)is one of the most relevant viruses in the poultry *** AI virus(AIV)transmission from birds to human causing severe cases and mortality enhanced the magnitude of AI for public ***,the AIV diagnosis laboratories should be able to detect and identify endemic,epidemic and seasonal influenza strains and other wildlife influenza subtypes that cross the country’s *** development in quality controls in according with international rules comes to improve the performance of *** this purpose,the Brazilian Reference Laboratory for Avian Influenza(LANAGRO-SP)established a cooperation with the World Organization for Animal Health(OIE)to produce AIV master seeds,inactivated antigens and antiserum to attend the necessities of Brazil and other South America countries under the high quality control for all *** of AIV master seed lots and seventeen of inactivated antigens lots produced reached hemagglutination(HA)titers of 1:512 and 1:256,*** addition,fifteen AIV antiserum lots with hemagglutination inhibition(HI)titers reaching 1:4,096 were *** AIV reference reagents produced and applied in laboratory routine successfully.

关键词： Avian influenza virus reference reagents subtypes quality control Brazil

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