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Expert consensus on the diagnosis and treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children

World Journal of pediatrics 2024年第9期20卷 901-914页

作者： ying-shuo Wang Yun-Lian Zhou Guan-Nan Bai shu-Xian Li Dan Xu Li-Na chen Xing chen xiao-Yan Dong Hong-Min Fu Zhou Fu Chuang-Li Hao jian-guo Hong En-Mei liu Han-Min liu xiao-Xia Lu Zheng-Xiu Luo Lan-fang Tang man Tian Yong Yin xiao-Bo zhang jian-Hua zhang Hai-lin zhang De-Yu Zhao shun-ying Zhao guo-Hong Zhu ying-Xue Zou Quan Lu Yuan-Yuan zhang Zhi-Min chen department of Pulmonology Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China department of Child Health Care Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China department of pediatric Pulmonology and Immunology West China Second University HospitalSichuan UniversityChengdu 610041China department of pediatrics Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021China department of Pulmonology Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200062China department of Pulmonary and Critical Care Medicine Kunming Children’s HospitalKunming 650034China department of Respiratory Medicine Children’s Hospital of Chongqing Medical UniversityChongqing 400014China department of Pulmonology Children’s Hospital of Soochow UniversitySuzhou 215003China department of pediatrics Shanghai General Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai 200080China department of Respiratory Medicine Wuhan Children’s HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430015China department of Respiratory Medicine Children’s Hospital of Nanjing Medical UniversityNanjing 210008China department of Respiratory Medicine Shanghai Children’s Medical CenterShanghai Jiao Tong University School of MedicineShanghai 200127China department of Respiratory Medicine Children’s Hospital of Fudan UniversityShanghai 201102China department of pediatric Pulmonology Xinhua HospitalShanghai Jiaotong University School of MedicineShanghai 201102China department of pediatric Respiratory Medicine The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325027China National Clinical Research center for Respiratory Diseases Beijing Children’s HospitalCapital Medical UniversityBeijing 100045China Departmen

Background Mycoplasma pneumoniae(***)is a significant contributor to community-acquired pneumonia among *** 1968,when a strain of *** resistant to macrolide antibiotics was initially reported in Japan,macrolide-resistant ***(MRMP)has been documented in many countries worldwide,with varying incidence *** infections lead to a poor response to macrolide antibiotics,frequently resulting in prolonged fever,extended antibiotic treatment,increased hospitalization,intensive care unit admissions,and a significantly higher proportion of patients receiving glucocorticoids or second-line *** 2000,the global incidence of MRMP has gradually increased,especially in East Asia,which has posed a serious challenge to the treatment of *** infections in children and attracted widespread attention from ***,there is still no global consensus on the diagnosis and treatment of MRMP in *** We organized 29 Chinese experts majoring in pediatric pulmonology and epidemiology to write the world’s first consensus on the diagnosis and treatment of pediatric MRMP pneumonia,based on evidence *** evidence searches and reviews were conducted using electronic databases,including PubMed,Embase,Web of science,CNKI,Medline,and the Cochrane *** used variations in terms for“macrolide-resistant”,“Mycoplasma pneumoniae”,“MP”,“***”,“pneumonia”,“MRMP”,“lower respiratory tract infection”,“Mycoplasma pneumoniae infection”,“children”,and“pediatric”.Results Epidemiology,pathogenesis,clinical manifestations,early identification,laboratory examination,principles of antibiotic use,application of glucocorticoids and intravenous immunoglobulin,and precautions for bronchoscopy are *** and rapid identification of gene mutations associated with MRMP is now available by polymerase chain reaction and fluorescent probe techniques in respiratory *** the resistance rate to mac

关键词： Child macrolide-resistant Mycoplasma pneumoniae Recommendation Diagnosis Treatment

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Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children

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World Journal of pediatrics 2024年第1期20卷 11-25页

作者： Xian-Li zhang Xi zhang Wang Hua Zheng-De Xie Han-Min liu Hai-lin zhang Bi-Quan chen Yuan chen Xin sun Yi Xu sai-Nan shu shun-ying Zhao Yun-xiao shang ling Cao Yan-Hui jia Luo-Na lin Jiong Li Chuang-Li Hao xiao-Yan Dong Dao-Jiong lin Hong-Mei Xu De-Yu Zhao Mei Zeng Zhi-Min chen Li-su huang department of Infectious Disease Children's HospitalZhejiang University School of Medicine3333 Binsheng RoadBinjiang DistrictHangzhou 310052China Clinical Research Unit Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Beijing pediatric Research Institute Beijing Children's HospitalCapital Medical UniversityBeijingChina department of pediatric Pulmonology West China Second University HospitalSichuan UniversityChengduChina department of pediatric Pulmonology the Second Affiliated Hospital&Yuying Children's HospitalWenzhou Medical UniversityWenzhouChina department of Infectious Disease Anhui Provincial Children's HospitalHefeiChina department of pediatrics the Second Hospital of Hebei Medical UniversityShijiazhuangChina department of pediatrics Xijing Hospitalthe Fourth Military Medical UniversityXi'anChina department of Infectious Disease Guangzhou Women and Children's Medicine CenterGuangzhou Medicine UniversityGuangzhouChina department of pediatrics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina department of Respiratory Disease Beijing Children's HospitalCapital Medical UniversityBeijingChina department of pediatric Respiratory Shengjing Hospital of China Medical UniversityShenyangChina Respiratory department Children's Hospital Affiliated to Capital Institute of PediatricsBeijingChina department of Clinical Epidemiology Aarhus UniversityAarhusDenmark department of Respirology Children's Hospital of Soochow UniversitySuzhouChina department of Respiratory Children's Hospital of ShanghaiChildren's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina department of Infectious Disease Hainan Women and Children's Medical CenterHaikouChina department of Infectious Disease Children's Hospital of Chongqing Medical UniversityChongqingChina department of Respiratory Children's Hospital of Nanjing Medical UniversityNanjingChina department of Infectious Di

Background Respiratory syncytial virus(RsV)is the leading global cause of respiratory infections and is responsible for about 3 million hospitalizations and more than 100,000 deaths annually in children younger than 5 years,representing a major global healthcare *** is a great unmet need for new agents and universal strategies to prevent RsV infections in early life.A multidisciplinary consensus development group comprising experts in epidemiology,infectious diseases,respiratory medicine,and methodology aims to develop the current consensus to address clinical issues of RsV infections in *** sources The evidence searches and reviews were conducted using electronic databases,including PubMed,Embase,Web of science,and the Cochrane Library,using variations in terms for"respiratory syncytial virus","RsV","lower respiratory tract infection","bronchiolitis","acute","viral pneumonia","neonatal","infant""children",and"pediatric".Results Evidence-based recommendations regarding diagnosis,treatment,and prevention were proposed with a high degree of *** supportive care remains the cornerstone for the management of RsV infections,new monoclonal antibodies,vaccines,drug therapies,and viral surveillance techniques are being rolled *** This consensus,based on international and national scientific evidence,reinforces the current recommendations and integrates the recent advances for optimal care and prevention of RsV *** improvements in the management of RsV infections will require generating the highest quality of evidence through rigorously designed studies that possess little bias and sufficient capacity to identify clinically meaningful end points.

关键词： Consensus prevention Respiratory syncytial virus Treatment

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Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis:a nationwide retrospective study in china

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World Journal of pediatrics 2024年第5期20卷 506-516页

作者： Li-Wen Tan Jun-Li Wan Chun-Hua Zhu Hong Xu Zheng-Kun Xia Li-Zhi chen xiao-Chuan wu fang Wang xiao-Rong liu cheng-Guang Zhao xiao-Zhong Li jian-Hua mao xiao-Wen Wang Wen-Yan huang Yu-Hong Li jian-jiang zhang shi-Pin Feng Jun Yang jiao-jiao liu Chun-lin Gao Li-Ping Rong Lan-Jun shuai Ke Xu He-jia zhang Qiu Li Ai-Hua zhang Mo Wang department of Nephrology Children’s Hospital of Chongqing Medical UniversityZhongshan 2nd Rd.136Chongqing400014China Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChildren’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of pediatrics Children’s Hospital of Chongqing Medical UniversityChongqingChina department of Nephrology Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing210008China department of Nephrology Children’s Hospital of Fudan UniversityNational Paediatric Medical Center of ChinaShanghaiChina department of pediatrics Jinling HospitalNanjing Medical UniversityNanjingChina department of pediatrics Jinling HospitalThe First School of Clinical MedicineSouthern Medical UniversityNanjingChina department of pediatrics Jinling HospitalMedical School of Nanjing UniversityNanjingChina department of pediatric Nephrology and Rheumatology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouChina department of pediatrics The Second Xiangya Hospital of Central South UniversityChangshaChina department of pediatrics Peking University First HospitalBeijingChina department of Nephrology Beijing Children’s HospitalCapital Medical UniversityBeijing100045China National center for children’s Health BeijingChina department of pediatrics Shengjing Hospital of China Medical UniversityShenyangChina department of Nephrology and Immunology Children’s Hospital of Soochow UniversitySuzhouChina department of Nephrology Children HospitalZhejiang University School of MedicineHangzhouChina department of Nephrology Wuhan Children’s Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science&TechnologyWuhanChina department of Nephrology and Rheumatology Shanghai Children’s HospitalSchool

Background pediatric antineutrophil cytoplasmic antibody-associated vasculitis(AAV)is a life-threatening systemic vasculitis featured by liability to renal ***,there are few studies on the risk factors and predictive models for renal outcomes of AAV in *** Data from 179 AAV children in multiple centers between January 2012 and march 2020 were collected *** risk factors and predictive model of end-stage renal disease(EsRD)in AAV were *** Renal involvement was the most typical manifestation(95.5%),and the crescent was the predominant pathological lesion(84.9%).The estimated glomerular filtration rate(eGFR)was evaluated in 114 patients,of whom 59.6%developed EsRD,and the median time to EsRD was 3.20 *** eGFR[P=0.006,odds ratio(OR)=0.955,95%confidence interval(CI)=0.924–0.987]and the percentages of global glomerulosclerosis(pGGs;P=0.018,OR=1.060,95%CI=1.010–1.112)were independent risk factors for EsRD of renal *** on the pGGs and eGFR at renal biopsy,we developed three risk grades of EsRD and one predictive *** Kaplan‒Meier curve indicated that renal outcomes were significantly different in different risk grades(Pserum creatinine at baseline,the predictive model had higher accuracy(0.86 versus 0.58,Psus 0.92)in external *** Renal involvement is the most common manifestation of pediatric AAV in china,of which more than half deteriorates into *** predictive model based on eGFR at renal biopsy and the pGGs may be stable and accurate in speculating the risk of EsRD in AAV children.

关键词： Antineutrophil cytoplasmic antibody End-stage renal disease Glomerulonephritis pediatric nephrology Vasculitis

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Current Mycoplasma pneumoniae epidemic among children in shanghai:unusual pneumonia caused by usual pathogen

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World Journal of pediatrics 2024年第1期20卷 5-10页

作者： xiao-Bo zhang Wen He Yong-Hao Gui Quan Lu Yong Yin jian-Hua zhang xiao-Yan Dong ying-Wen Wang ying-Zi Ye Hong Xu jia-Yu Wang bing shen Dan-Ping Gu Li-Bo Wang Yi Wang department of Respiratory Medicine Children's Hospital of Fudan University399 Wanyuan RoadShanghai 201102China state Key Laboratory of genetic Engineering at school of Life sciences Institute of Reproduction&DevelopmentChildren's Hospital of Fudan UniversityShanghaiChina department of Respiratory Medicine Children's Hospital of Shanghai Jiao Tong UniversityShanghaiChina department of Respiratory Medicine Shanghai Children's Medical CenterAffiliated to Shanghai Jiaotong University School of MedicineShanghaiChina department of pediatric Respiratory Xinhua HospitalAffiliated to Shanghai Jiaotong University School of MedicineShanghaiChina department of Nursing Children's Hospital of Fudan UniversityShanghaiChina department of Infectious Diseases Children's Hospital of Fudan UniversityShanghaiChina department of Nephrology Children's Hospital of Fudan UniversityShanghaiChina NHC Key Laboratory of Neonatal Diseases Children's Hospital of Fudan UniversityShanghaiChina shanghai shenkang hospital Development center ShanghaiChina center for medical Quality Control management of shanghai ShanghaiChina department of Neurology Children's Hospital of Fudan University399Wanyuan RoadShanghai 201102China

Mycoplasma pneumoniae(***),primarily transmitted through respiratory droplets when infected individuals cough or sneeze,is a common cause of communityacquired pneumonia,especially among school-age children and *** infection occurs endemically with an epidemic peak every few *** worldwide incidence confirmed by direct test methods was reported to be 8.61%between 2017 and 2020 across all age groups[1].

关键词： pneumonia epidemic respiratory

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A multicenter prospective study on the management of hepatoblastoma in children:a report from the Chinese children's Cancer Group

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World Journal of pediatrics 2024年第6期20卷 590-601页

作者： Meng-Jie Tang xiao-Li ma Xiang-ling He Wei-Hua Pan xiao-Hong zhang sha-Yi jiang Ju Gao Fu Li Wei Yao song Gu Wei-ling zhang Qiang Zhao shi-Hao huang Yong-Jun fang Wei liu Hui-Zhong Niu Chun-Mei Wang Li-Rong sun Hui Gao Yun-Peng Dai shun-gen huang Zhi-Yong Zhong Xi-Ge Wang Zhong-Rong Li Liang-Chun Yang Ye-Ming wu Huan-Min Wang Xin sun xiao-Jun Yuan department of pediatric Hematology/Oncology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNo.1665Kongjiang RoadYangpu DistrictShanghai 200092China medical Oncology department Pediatric Oncology CenterBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China department of Hematology/Oncology Children's Medical CenterHunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 41005China department of pediatric surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China department of Hematology/Oncology Guangzhou Women and Children's Medical CenterNational Children's Medical Center for South Central RegionGuangzhou 510623China department of Hematology Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200062China department of pediatrics West China Second University HospitalSichuan UniversityChengdu 610041China department of Hematology/Oncology Qilu Children's Hospital of Shandong UniversityJinan 250022China department of pediatric surgery Children's Hospital of Fudan UniversityShanghai 201102China department of general surgery Shanghai Children's Medical Center(National Children's Medical Center-Shanghai)Shanghai Jiao Tong University School of MedicineShanghai 200127China department of pediatrics Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China department of pediatric Oncology Tianjin Medical University Cancer Institute and HospitalTianjin 300060China department of Hematology/Oncology Children's Hospital of Nanjing Medical UniversityNanjing 210008China department of Hematology/Oncology Henan Children's HospitalZhengzhou 450018China department of pediatric general surgery Hebei Children's Hospital of Hebei Medical UniversityShijiazhuang City 050031China children's hospital the First Affliated Hospital of Zhengzhou UniversityZhengzhou 450052China department of Paediatric

Background This study aimed to identify survival risk factors in Chinese children with hepatoblastoma(HB)and assess the effectiveness of the new treatment protocol proposed by the Chinese children's Cancer Group(CCCG)in *** A multicenter,prospective study that included 399 patients with HB from January 2015 to June 2020 was *** demographics,treatment protocols,and other related information were *** regression models and Kaplan-Meier curve methods were *** The 4-year event-free survival(EFs)and overall survival(Os)were 76.9 and 93.5%,*** 4-year EFs rates for the very-low-risk,low-risk,intermediate-risk,and high-risk groups were 100%,91.6%,81.7%,and 51.0%,*** 4-year 0s was 100%,97.3%,94.4%,and 86.8%,*** regression analysis found that age,tumor rupture(R+),and extrahepatic tumor extension(E+)were independent prognostic factors.A total of 299 patients had complete remission,and 19 *** with declining alpha-fetoprotein(AFP)>75%after the first two cycles of neoadjuvant chemotherapy had a better EFs and Os than those≤75%.Conclusions The survival outcome of HB children has dramatically improved since the implementation of CCCG-HB-2016 ***≥8 years,R+,and E+were independent risk factors for *** with a declining AFP>75%after the first two cycles of neoadjuvant chemotherapy had better EFs and Os.

关键词： Alpha-fetoprotein Hepatoblastoma Multicenter Prospective study survival

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Assessment of pulmonary blood supply in children with tetralogy of fallot by atrial volume measured with three-dimensional echocardiography

Assessment of pulmonary blood supply in children with tetral...

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第二届长三角超声医学论坛暨2009年浙江省超声医学学术年会

作者： pediatric heart center,children’s hospital of fudan university,department of pediatrics medical school fudan university,shanghai 2.0032.china xiao-jing ma guo-ying huang fang liu lin wu bing jia zhang-gen chen

Objective To evaluate the feasibility of using atrial volume with three-dimensional echocardiography (3DE) in assessing pulmonary blood in children with tetralogy of Fallot(TOF). Methods Twenty cases of TOF aged(3.2±...

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Methodological study on real-time three-dimensional echo-cardiography and its application in the diagnosis of complex congenital heart disease

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Chinese medical Journal 2006年第14期119卷 1190-1194页

作者： chen guo-zhen, huang guo-ying, LIANG Xue-cun, ma xiao-jing, chen Wei-da, TAO Zi-yu and lin Qi-shan pediatric heart center, children’s hospital of fudan university department of pediatrics, shanghai medical College, shanghai 2.0032, china china） 200032

Background Real-time three-dimensional echocardiography （RT-3DE） has made revolutionized improvements of cardiac imaging during the past few years. However, there is no standard examination method for RT-3DE so far. This study aimed to establish the diagnostic method of RT-3DE and evaluate its application in the diagnosis of complex congenital heart diseases （CHD）. Methods Fifty patients with complex CHD were examined by RT-3DE with modes of Live 3DE and Full Volume. A series of novel volumetric views combined with Van Praagh sequential segmental approach were introduced to reveal the pathological morphology of the hearts, which were compared with the findings of two-dimensional echocardiography （2DE）, angiography and cardiac surgery. Results In 50 patients, 190 image acquisitions of Full Volume were performed at several acoustic windows including subcostal, apical and parasternal regions. Among them, 94.2% （179/190） of image acquisitions were successful. Most sectional volumetric views could be clearly displayed in 92.6% of the successful image acquisitions. However, sectional volumetric views could not be clearly displayed in 7.4%, which was mainly due to poor perspective conditions of examination location, improper instrument multi-parameter setting and insufficient information of whole heart captured in Full Volume acquisitions. As compared with surgical findings and angiography, RT-3DE made correction to the diagnoses in 2 cases including 1 with corrected transposition of the great arteries and the other with single atrium and mitral cleft. The diagnoses initially made by 2DE for these 2 patients were double outlet right ventricle with transposition of the great arteries and complete atrio-ventricular septal defect. Conclusions RT-3DE can clearly display the pathological morphology of complex CHD by a series of novel volumetric views combined with sequential segmental approach through providing more spatial informative cardiovascular structures, which pro

关键词： congenital heart disease three-dimensional echocardiography real-time imaging

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Diagnosis,treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children:experts'consensus statement updatedforthe Omicron variant

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World Journal of pediatrics 2024年第3期20卷 272-286页

作者： Rong-Meng jiang Zheng-De Xie Yi jiang xiao-Xia Lu Run-Ming Jin Yue-Jie Zheng Yun-xiao shang Bao-Ping Xu Zhi-sheng liu gen Lu Ji-Kui Deng Guang-Hua liu xiao-Chuan Wang jian-she Wang Lu-Zhao Feng Wei liu Yi Zheng sai-Nan shu Min Lu Wan-Jun Luo Miao liu Yu-Xia Cui Le-Ping Ye A-Dong shen Gang liu Li-Wei Gao Li-Juan Xiong Yan Bai Li-Kai lin Zhuang Wei Feng-Xia Xue Tian-You Wang Dong-Chi Zhao jian-Bo shao Daniel Kwok-keung Ng Gary Wing-kin Wong Zheng-Yan Zhao Xing-Wang Li Yong-Hong Yang Kun-ling shen Diagnosis and Treatment center of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Beijing Key Laboratory of pediatric Respiratory Infection Diseases Key Laboratory of Major Diseases in ChildrenMinistry of EducationNational Clinical Research Center for Respiratory DiseasesResearch Unit of Critical Infection in ChildrenChinese Academy of Medical Sciences2019RU016Laboratory of Infection and VirologyBeijing Pediatric Research InstituteBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China department of pediatrics Renmin Hospital of Wuhan UniversityWuhan 430060China department of Respiratory Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China department of pediatrics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China department of Respiratory Shenzhen Children's HospitalShenzhen 518038China department of pediatric Respiratory Shengjing Hospital Affiliated to China Medical UniversityShenyang 110004China department of Respiratory Beijing Children's HospitalCapital Medical UniversityNational Clinical Research Center for Respiratory DiseasesNational Center for Children's HealthBeijing 100045China department of Neurology Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China department of Respiratory Guangzhou Women and Children's Medical CenterGuangzhou 510623China department of Infectious Diseases Shenzhen Children's HospitalShenzhen 518038China department of pediatrics Fujian Branch of Shanghai Children's Medical CenterFujian Children's HospitalFuzhou350005China department of Clinical Immunology and Allergy Children's Hospital of Fudan UniversityNational Center for Children's HealthShanghai 201102China department of Infectious Diseases Children's Hospital of Fudan UniversityNational Center for Children's Health.Shanghai

It has been more than 3 years since the novel coronavirus(sARs-CoV-2)pandemic raged *** coronavirus disease 2019(COVID-19)has greatly influenced human *** to data from the World Health Organization(WHO),there were ove... 详细信息

关键词： prevention infection statement

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Best practice for infection prevention in pediatric respiratory clinics during the COVID‑19 epidemic

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World Journal of pediatrics 2020年第4期16卷 326-332页

作者： jing zhang Lei zhang Yong Yin Quan Lu jian‑guo Hong xiao‑Bo zhang xiao‑jian Zhou Li‑Bo Wang jian‑Hua zhang Min Lu xiao‑Yan Dong Jie shao Yan‑Ming Lu Jun Yu Li Gu Respiratory Disease Group,pediatric Committee of shanghai medical Association,shanghai,china department of Respiratory Medicine Shanghai Children’s Medical CenterShanghai Jiao Tong University School of MedicineNo.1678 Dongfang RoadShanghaiChina department of Respiratory Medicine Children’s Hospital of Shanghai Jiao Tong UniversityShanghaiChina department of pediatrics Shanghai General HospitalShanghai Jiao Tong UniversityShanghaiChina department of Respiratory Medicine Children’s Hospital of Fudan UniversityShanghaiChina department of Respiratory Medicine XinHua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina department of pediatrics Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina department of pediatrics Renji HospitalShanghai Jiao Tong University School of MedicineShanghaiChina department of pediatrics Shanghai FengXian District Central HospitalShanghaiChina department of pediatrics Shanghai Tenth People’s HospitalTong Ji UniversityShanghaiChina 不详

During the COVID-19 epidemic,it is important for ensuring infection prevention and control in the pediatric respiratory ***,we introduced the practice of infection prevention and control in pediatric respiratory clinics in *** measures for patients who visit respiratory clinics,quality control for pediatric respiratory clinics and other preventive measures for related examinations and treatment have been introduced in this review article.

关键词： prevention pediatric respiratory

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Current status of screening, diagnosis, and treatment of neonatal congenital heart disease in china

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World Journal of pediatrics 2018年第4期14卷 313-314页

作者： xiao-jing ma guo-ying huang heart center Children’s Hospital of Fudan University399 Wanyuan RoadShanghai 201102China National children’s medical center 399 Wanyuan RoadShanghai 201102China shanghai Key Lab of Bir th Defects 399 Wanyuan RoadShanghai 201102China

Congenital heart disease (CHD) has become the most com-mon birth defect in china. According to the 'Report on the Prevention and Control of Birth Defects in china (2012)' [ 1 ], in 2011, the prevalence of CHD was 4.095 of every 1000 live births, which accounted for the first place in all birth defects in recent years. Because of the large population base in china, the number of new cases of CHD per year is huge. It is estimated that more than 130 thousand patients with CHD will be added per year in china. According to another study reported in 2014, CHD was present in 8.94 of every 1000 live births in china, among which, the incidence of critical CHD (CCHD), causing death or requiring invasive intervention during the first month of life, was 2.91‰ [ 2 ].

关键词： Current status screening diagnosis treatment of neonatal congenital heart disease

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