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Journal of Pharmaceutical Analysis 2021年第5期11卷 661-666页

作者： Ruxandra Chira Jens Fangmeyer Ioan o.Neaga Valentin Zaharia Uwe Karst Ede Bodoki Radu oprean Analytical Chemistry Department “Iuliu Hat¸ieganu”University of Medicine and Pharmacy400349Cluj-NapocaRomania University of Münster Institute of Inorganic and Analytical Chemistry48149MünsterGermany organic Chemistry Department “Iuliu Hat¸ieganu”University of Medicine and Pharmacy400012Cluj-NapocaRomania

Considering the frequent use of netupitant in polytherapy,the elucidation of its oxidative metabolization pattern is of major ***,there is a lack of published research on the redox behavior of this novel neurokinin-1 receptor ***,this study was performed to simulate the intensive hepatic biotransformation of netupitant using an electrochemically driven *** of the known enzyme-mediated reactions occurring in the liver(i.e.,N-dealkylation,hydroxylation,and Noxidation)were successfully mimicked by the electrolytic cell using a boron-doped diamond working *** products were separated by reversed-phase high-performance liquid chromatography and identified by high-resolution mass *** from its ability to pinpoint formerly unknown metabolites that could be responsible for the known side effects of netupitant or connected with any new perspective concerning future therapeutic indications,this electrochemical process also represents a facile alternative for the synthesis of oxidation products for further in vitro and in vivo studies.

关键词： Netupitant oxidative metabolism Neurokinin-1 antagonist EC/LC/MS

中、美高等学校体育竞赛组织与管理的比较研究

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山东体育学院学报 1997年第2期13卷 70-75页

作者：王永盛姜明青岛大学体育教学部副教授266071 山东体育学院田径教研室副教授济南250063

列举并分析了中、美两国高等学校体育竞赛的现状与特点,从两国国家、省(州)、市的不同层次的高校校际体育竞赛的组织和管理机构,到竞赛体制以及对运动员的学籍管理等方面进行了比较、分析研究,为我国高校体育竞赛制度的改革和完善提供... 详细信息

列举并分析了中、美两国高等学校体育竞赛的现状与特点,从两国国家、省(州)、市的不同层次的高校校际体育竞赛的组织和管理机构,到竞赛体制以及对运动员的学籍管理等方面进行了比较、分析研究,为我国高校体育竞赛制度的改革和完善提供借鉴。

关键词：中国美国高等学校体育协会体育竞赛组织机构

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滑坡地段隧道变形整治中抗滑桩的设计方法

山地学报 2003年第5期21卷 620-623页

作者：陶志平周德培西南交通大学土木工程学院西南交通大学土木工程学院四川成都610031

针对滑坡地段隧道变形整治中抗滑桩的设计问题,提出了典型的抗滑桩类型及各类抗滑桩的适用条件,指出了确定抗滑桩合理位置的方法,讨论了抗滑桩设计中应注意的问题,并对具体的设计过程进行了举例说明。

关键词：隧道变形抗滑桩设计方法

尼日利亚Gongola盆地地层放射性热产量与生烃潜力

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石油勘探与开发 2016年第3期43卷 411-416页

作者： oYEBANJo o M AJAYI T R TCHoKoSSA P Natural History Museum Obafemi Awolowo University Department of Geology Obafemi Awolowo University Department of Physics Obafemi Awolowo University

以取自尼日利亚上贝努埃地槽Gongola盆地Kolmani-1井的样品为基础,对其放射性热产量进行了估算,并对放射性热产量对沉积物生油气潜力的影响进行了分析。研究采用精确标定的碘化钠伽马射线检测系统,对不同层组的38块样品（取样间隔73.2 m... 详细信息

以取自尼日利亚上贝努埃地槽Gongola盆地Kolmani-1井的样品为基础,对其放射性热产量进行了估算,并对放射性热产量对沉积物生油气潜力的影响进行了分析。研究采用精确标定的碘化钠伽马射线检测系统,对不同层组的38块样品（取样间隔73.2 m,包括砂岩、页岩、含煤页岩、砂质页岩、泥质砂岩）进行了40K、238U及232Th的放射性分析。研究结果表明,沉积物中放射性元素的放射性浓度存在显著变化,40K浓度最高;沉积物放射性热产量为228.44～1 412.82 p W/kg;Kolmani-1井砂岩和砂质页岩属于低热产量沉积物,含煤页岩、页岩及泥质砂岩属于中热产量沉积物,潜在烃源岩（页岩和含煤页岩层段）的放射性热产量值主要位于中热产量范围（750～1500 p W/kg）,同时具有生成液态烃和气态烃的能力。此外,沉积物的放射性热量约占盆地总地表热通量的10.9%～20.9%,沉积物的放射性热量是总地表热通量的重要组成部分,应将其纳入盆地的热模拟。

关键词：地层放射性放射性热产量生烃潜力 Gongola盆地

Ecology of Upland Rice Plants and Seeds Subjected to Growth Regulator

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American Journal of Plant Sciences 2018年第1期9卷 60-73页

作者： Felipe Koch Manoela Andrade Monteiro Joao Roberto Pimentel Cristian Troyjack Itala Thaisa Padilha Dubal Eduardo Goncalves Borges Vinícius Jardel Szareski Gustavo Henrique Demari Lanes Beatriz Acosta Jaques Ivan Ricardo Carvalho Francisco Amaral Villela Tiago pedó Tiago Zanatta Aumonde Federal University of Pelotas Capao do LeaoBrazil

The objective of this work is to verify the influence of the plant regulator trinexapac-ethyl on plant growth and physiological quality of upland rice seeds. We used an upland rice genotype, and the growth regulator was the trinexapac-ethyl. The experiment was completely randomized in a 4 × 8 factorial design related to four concentrations of the plant regulator trinexapac-ethyl [0 (without growth regulator), 0.25, 0.50, and 0.75 L c.p. ha-1] and 7 plant collection times [14, 28, 42, 56, 70, 84, 98 days after emergence (DAE)], with four replicates. To determine growth attributes, we evaluated total dry matter, dry matter production rate, relative growth rate, leaf area ratio, leaf matter, leaf area index, solar energy conversion efficiency and partition of assimilates. The physiological quality of the seeds was evaluated based on germination, first germination count, field emergence, emergence speed index and seedling dry matter. Plant growth was affected by the growth regulator. Total dry matter, dry matter production rate and solar energy conversion efficiency decreased, while leaf area index, leaf area ratio and leaf matter increased due to the effects of the growth regulator. The dry matter partition of plants changed in plants subjected to the growth regulator, with a delay in the targeting of assimilates to reproductive organs and a greater allocation to roots at the end of the cycle in plants subjected to the doses 0.50 and 0.75 L·ha-1 of growth regulator. Seed vigor was adversely affected by the growth regulator.

关键词： oryza sativa L. Trinexapac-Ethyl Leaf Area Dry Matter Seed Vigor

Nitrogen Fertilization on Maize Sowing:Plant Growth and Seed Vigor

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American Journal of Plant Sciences 2018年第1期9卷 83-97页

作者： Cristian Troyjack Joao Roberto Pimentel Itala Thaísa Dubal Padilha Ruddy Alvaro Veliz Escalera Lanes Beatriz Acosta Jaques Felipe Koch Manoela Andrade Monteiro Gustavo Henrique Demari Vinicius Jardel Szareski Ivan Ricardo Carvalho Luis osmar Braga Schuch Tiago Zanatta Aumonde Tiago pedó Federal University of Pelotas Capao do LeaoBrazil

The management of fertilization in maize plants is a preponderant factor in the search for higher yields and obtaining quality seeds. In this sense, the study of nitrogen (N) management is predominant in improving the efficiency of its application. The objective of this study was to evaluate the growth, partition assimilation and vigor expression of maize seeds submitted at different doses of nitrogen applied at sowing. The treatments were constituted by different doses of nitrogen fertilization at sowing, being: 25%, 50%, 75% and 100% of the recommended dose for the crop, according to the recommendation of nitrogen fertilization. The plants were collected at regular intervals of 21 days after sowing until the end of the growth cycle. For the analysis of growth and partition of dry matter between the organs, the accumulation of dry matter and leaf area was measured. The experimental design was randomized blocks in a 4 × 7 factorial scheme (four N rates at sowing and seven collection times with three replications). The maize plants under the influence of nitrogen fertilization at sowing presented differential growth and distinct responses in the assimilated partition between their structures, with the intensity dependent on the dose used. Plants grown using 75% of the recommended dose of N at sowing had a higher relative growth rate, with more pronounced effects compared to the other doses. The expression of maize seed vigor increases to an increase of 82.5% N at sowing.

关键词： Emergence Speed Net Assimilation Rates Relative Growth Rates Zea mays L. Vigor

<i>oryza</i>Wild Species: An Alternative for Rice Breeding under Abiotic Stress Conditions

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American Journal of Plant Sciences 2018年第6期9卷 1093-1104页

作者： Viní cius Jardel Szareski Ivan Ricardo Carvalho Tiago Corazza da Rosa Simone Morgan Dellagostin Alan Junior de Pelegrin Mauricio Horbach Barbosa osmarino Pires dos Santos Dionei Schmidt Muraro Velci Queir&oacute z de Souza Tiago ped.oacute Tiago Zanatta Aumonde Camila Pegoraro Federal University of Pelotas Pelotas Brazil Federal University of Santa Maria Santa Maria Brazil Federal University of Pampa Bag&eacute Brazil

Rice (oryza sativa L.) presents a strategic role in social and economic levels. The aim of this study was to elucidate the presence of genetic variability for the genus oryza, and the possibility of using genotypes with wild characteristics in rice breeding programs. The oryza genus shows great genetic variability through wild genotypes available in the most varied environments around the world. The negative effects imposed by abiotic stresses such as flood, salinity, low temperatures, water deficiency and high temperatures may be minimized by the efficient identification of a genetic variability source from the oryza genus. Among the main wild species presented by the oryza genus, oryza glumaepatula stands out being an active source of germplasm. The occurrence and preservation of genetic variability of oryza genus is indispensable to obtain new rice genotypes, to guarantee food security for the human population, as well as to develop genotypes that adapt to climatic changes and natural adversities.

关键词： oryza sativa Beeding Germplasm Source Genetic Variability

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先天性膈疝的临床特点及外科治疗经验

新生儿科杂志 2002年第6期17卷 250-251页

作者：王淑芹王平刘宝富北京大学第一医院小儿外科 100034

为提高新生儿先天性膈疝(CDH)的早期诊断、治疗及预后水平,对28例先天性膈疝病例进行临床特征、手术过程回顾性分析。全部进行正位及侧位胸部X-线检查,5例做上消化道造影,13例做血气分析。X-线证实胸腔内有含水的肠管,腹腔没有气体,部... 详细信息

为提高新生儿先天性膈疝(CDH)的早期诊断、治疗及预后水平,对28例先天性膈疝病例进行临床特征、手术过程回顾性分析。全部进行正位及侧位胸部X-线检查,5例做上消化道造影,13例做血气分析。X-线证实胸腔内有含水的肠管,腹腔没有气体,部分患儿有胃食管返流(GER)、存在吸入性肺炎或脑发育不全;血气分析显示部分婴儿严重的缺氧、呼吸性酸中毒;消化道造影显示结肠或小肠在胸腔内。结果:2例新生儿放弃治疗,26例患儿手术治疗,3例死亡,23例病人恢复良好。结论:对患有先天性膈疝的新生儿必须早期诊断和手术治疗。

关键词：先天性膈疝外科手术治疗临床经验预后临床特点

尼日利亚Ariki油田地层层序、构造格架与油气运聚

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石油勘探与开发 2016年第1期43卷 77-83页

作者： AHANEKU C V oKoRo A U oDoH B I ANoMNEZE D o CHIMA K I EJEKE C F oKoLI I N Department of Geological Sciences Nnamdi Azikiwe University Department of Subsurface and Engineering Nubian Group Department of Physics/Geology/Geophysics Federal University

综合应用测井和三维地震数据,对尼日尔三角洲盆地西部浅海沉积带Ariki油田的构造格架和地层层序进行了解释,并开展了断裂控藏分析。该油田主力储集层Agbada组内识别出5个最大洪泛面和5个层序界面,构造格架受控于伸展构造活动所形成的主... 详细信息

综合应用测井和三维地震数据,对尼日尔三角洲盆地西部浅海沉积带Ariki油田的构造格架和地层层序进行了解释,并开展了断裂控藏分析。该油田主力储集层Agbada组内识别出5个最大洪泛面和5个层序界面,构造格架受控于伸展构造活动所形成的主断层、次级断层以及滚动背斜。研究区共发育7条断层,可划分为3个主断层和4个次级断层;在油田西翼,次级断层活动形成类似地堑和地垒的构造。通过断距分析,认为在1 800 ms以下,主断层断距加大,主断层作为油气运移通道;在1 800 ms以上,主断层断距变小,可以作为油气圈闭遮挡。研究区存在四面下倾的滚动背斜和次级断层控制的三面下倾闭合圈闭等多种远景构造圈闭,有利于提升石油区带的规模勘探潜力。

关键词：尼日尔三角洲 Ariki油田地层层序构造格架油气运聚滚动背斜断层封堵性

Family integrated care:Supporting parents as primary caregivers in the neonatal intensive care unit

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pediatric Investigation 2021年第2期5卷 148-154页

作者： Chandra Waddington Nicole Rvan Veenendaal Karel o’Brien Neil Patel for the International Steering Committee for Family Integrated Care Faculty of Nursing University of TorontoCanada oLVG Amsterdamthe Netherlands Emma Children’s HospitalAmsterdam UMC University of AmsterdamVrije UniversiteitAmsterdamthe Netherlands Mount Sinai Hospital TorontoCanada Royal Hospital for Children GlasgowUK The members of the International Steering Committee for Family Integrated Care are listed in the supporting information

Family integrated care (FICare) is a collaborative model of neonatal care which aims to address the negative impacts of the neonatal intensive care unit (NICU) environment by involving parents as equal partners, minimizing separation, and supporting parent-infant closeness. FICare incorporates psychological, educational, communication, and environmental strategies to support parents to cope with the NICU environment and to prepare them to be able to emotionally, cognitively, and physically care for their infant. FICare has been associated with improved infant feeding, growth, and parent wellbeing and self-efficacy;important mediators for long-term improved infant neurodevelopmental and behavioural outcomes. FICare implementation requires multi-disciplinary commitment, staff motivation, and sufficient time for preparation and readiness for change as professionals relinquish power and control to instead develop collaborative partnerships with parents. Successful FICare implementation and culture change have been applied by neonatal teams internationally, using practical approaches suited to their local environments. Strategies such as parent and staff meetings and relational communication help to break down barriers to change by providing space for the co-creation of knowledge, the negotiation of caregiving roles and the development of trusting relationships. The CoVID-19 pandemic highlighted the vulnerability within programs supporting parental presence in neonatal units and the profound impacts of parent-infant separation. New technologies and digital innovations can help to mitigate these challenges, and support renewed efforts to embed FICare philosophy and practice in neonatal care during the CoVID-19 recovery and beyond.

关键词： Family integrated care Neonatal intensive care Parent-child Caregivers