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采油工艺情报 1990年第2期 43-57页

作者： peak.,wt 王嘉淮

Catalytic Enantioselective Methanolysis of 4 -substituted-2-phenyl-5(4H)-oxazolones by Cinchonine

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Chinese Chemical Letters 1998年第7期9卷 605-606页

作者： Xie, LJ Hua, wt Beijing Univ Coll Chem & Mol Engn Beijing 100871 Peoples R China

Cinchonine alkaloid catalyzed enantioselective methanolysis of six 4-substituted 2-phenyl-5(4H)-oxazolones to (S)-methyl N-benzoyl-alpha-amino acid esters with 10-33% e.e and 72-81% yield.

关键词： cinchonine 5(4H)-oxazolone cataytic asymmetric reaction dynamic-kinetic resolution enantioselective

One-Pot Synthesis of Substituted Cyclohexanes from Condensation of Aldehyde and Methylketone

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Chinese Chemical Letters 1998年第4期9卷 329-332页

作者： Yin, YG Cheung, KK Wong, wt Jingzhou Teachers Coll Dept Chem Jingzhou 434100 Hubei Peoples R China Univ Hong Kong Dept Chem Hong Kong Hong Kong

Three asymmetrically substituted cyclohexanes were prepared from one-pot reactions of aldehydes and methylketones, and the products were characterized by single crystal structure analysis, NMR spectroscopy and microan... 详细信息

关键词： Michael reaction intermolecular condensation substituted cyclohexane

Supramolecular Metal Complex with Ferrocene-conjugated Macrocyclic Triaza Crown Ether as Ligand and Its Electrochemical Property

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Chinese Chemical Letters 1998年第3期9卷 269-272页

作者： Yin, YG Cheung, KK Wong, wt Jingzhou Teachers Coll Dept Chem Jingsha 434100 Hubei Peoples R China Univ Hong Kong Dept Chem Hong Kong Peoples R China

A tetranuclear complex [Co(III)(2)(L)(2)(AcO)(2)(OH)](AcO)(2I). 4H(2)O (L = N-ferrocenylmethyl-1,4,7-triaza-cyclononane) was prepared from ligand L . HI and its crystal structure was determined. The crystal exists in P2(1)(/)a space group and its cell parameters are a = 14.285(3)Angstrom, b = 19.888(3)Angstrom, c = 19.133(3)Angstrom; beta = 109.12(2)degrees; V = 5135.8 Angstrom(3); Z = 4. Electrochemical investigation reveals that the oxidation potential of ferrocenyl group in 1 has a 0.11V-positive-shift from that of the ferrocenyl group in ***.

关键词： supermolecule ferrocene host-guest electronic interaction

Influence of Experimental Parameters on Reactive Magnetron Sputtering CN_x Thin Films

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Journal of Materials Science & Technology 1997年第2期13卷 154-156页

作者： Zheng, wt Ding, T Ivanov, I Sundgren, JE JILIN UNIV DEPT MAT SCICHANGCHUN 130023PEOPLES R CHINA LINKOPING UNIV DEPT PHYSS-58183 LINKOPINGSWEDEN

Carbon nitride thin films were deposited on Si(001) using unbalanced magnetron sputtering at different experimental parameters. The effects of nitrogen partial pressure, substrate temperature and substrate bias on the... 详细信息

关键词： Carbon

Implications of Withaferin A in neurological disorders

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Neural Regeneration Research 2021年第2期16卷 304-305页

作者： Natasha Ram Stephanie L.peak.Andres R.Perez Umesh K.Jinwal Department of Pharmaceutical Sciences Taneja College of PharmacyUniversity of South FloridaTampaFLUSA

Extract from the medicinal herb Withania somnifera(WS),commonly known as Ashwagandha,has therapeutic implications in various conditions such as infection,inflammation,cancer,stress,neurodegenerative diseases,heart dis... 详细信息

关键词： inflammation diseases infection

Comments on“Hepatic radioembolization with yttrium-90 glass microspheres for treatment of primary liver cancer”by Cao et al,Chin Med J 1999;112:430-432

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Chinese Medical Journal 2001年第4期114卷 97-98页

作者： SHo WY Lau wt Leung Chinese Univ Hong Kong Prince Wales Hosp Dept Surg Shatin Hong Kong Peoples R China Chinese Univ Hong Kong Prince Wales Hosp Dept Clin Oncol Shatin Hong Kong Peoples R China

Editors,　　We would like to congratulate Cao and his colleagues on the extremely good mean survival rate of 19.5 months achieved in 17 patients with non-resectable liver cancer (16 primary and 1 metastatic).1　Because the results of their study sounds so promising, centres having access to glass yttrium-90 (90Y) microspheres may want to try their methods. It is therefore necessary to clarify some of the points mentioned in their report.

关键词： yttrium Comments on

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当前中国家庭的六大趋势

Synthesis, Structure of a Symmetrically Substituted Stilbene with Strong Two-photon Absorption and Up-converted Blue Fluorescence

视野 2025年第2期 23页

作者： wt

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Chinese Chemical Letters 2001年第11期12卷 1001-1004页

作者： Wang, XM Zhou, GY Yu, wt Jiang, MH Shandong Univ State Key Lab Crystal Mat Jinan 250100 Peoples R China

Efficient Ti-catalyzed reductive coupling methodology was first employed to synthesize the symmetrical bis-donor stilbene, trans-4, 4'-bis[diphenyl amino] stilbene (BDPAS). X-ray diffraction analyses reveal that this new crystal belongs to the triclinic crystal system of centro-symmetric P-1 space group. The DBPAS solution, with the linear transmission at wavelength of greater than or equal to 450 nm, possesses large two-photon absorption cross section as high as 39.4x10(-48) cm(4).s/photon resulting in strong two-photon induced blue fluorescence of 460 nm, pumped by 740 nm laser irradiation.

关键词： symmetrical bis-donor stilbene synthesis crystal structure two-photon absorption two-photon-induced fluorescence

Stem cell therapy for the treatment of Leydig cell dysfunction in primary hypogonadism

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World Journal of Stem Cells 2016年第10期8卷 306-315页

作者： Taylor C peak.Nora M Haney William Wang Kenneth J DeLay Wayne J Hellstrom Department of Urology School of MedicineTulane University

The production of testosterone occurs within the Leydig cells of the testes. When production fails at this level from either congenital, acquired, or systemic disorders,the result is primary hypogonadism. While numerous testosterone formulations have been developed, none are yet fully capable of replicating the physiological patterns of testosterone secretion. Multiple stem cell therapies to restore androgenic function of the testes are under investigation. Leydig cells derived from bone marrow, adipose tissue, umbilical cord, and the testes have shown promise for future therapy for primary hypogonadism. In particular, the discovery and utilization of a group of progenitor stem cells within the testes, known as stem Leydig cells(SLCs), has led not only to a better understanding of testicular development, but of treatment as well. When combining this with an understanding of the mechanisms that lead to Leydig cell dysfunction, researchers and physicians will be able to develop stem cell therapies that target the specific step in the steroidogenic process that is deficient. The current preclinical studies highlight the complex nature of regenerating this steroidogenic process and the problems remain unresolved. In summary, there appears to be two current directions for stem cell therapy in male primary hypogonadism. The first method involves differentiating adult Leydig cells from stem cells of various origins from bone marrow, adipose, or embryonic sources. The second method involves isolating, identifying, and transplanting stem Leydig cells into testicular tissue. Theoretically, in-vivo re-activation of SLCs in men with primary hypogonadism due to age would be another alternative method to treat hypogonadism while eliminating the need for transplantation.

关键词： Stem cell therapy Leydig cells Primary hypogonadism Stem Leydig cells Testosterone Bone marrow-derived stem cells Adipose-derived mesenchymal stem cells