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A novel mortality risk score for emphysematous pyelonephritis:A multicenter study of the Global Research in the Emphysematous Pyelonephritis group

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Current Urology 2024年第1期18卷 55-60页

作者： Hegel Trujillo-Santamaría José Iván Robles-Torres Jeremy Yuen-Chun Teoh Yiloren Tanidir José Gadú Campos-Salcedo Edgar Iván Bravo-Castro Marcelo Langer Wroclawski W.S.Yeoh Santosh kumar Juan Eduardo Sanchez-Nuñez José Enrique Espinoza-Aznar Deepak Ragoori Saeed Bin Hamri Ong Teng Aik Cecil Paul Tarot-Chocooj Anil Shrestha Mohamed Amine Lakmichi Mateus Cosentino-Bellote Luis Gabriel Vázquez-Lavista Boukary Kabre Ho Yee Tiong José Gustavo Arrambide-Herrera Lauro Salvador Gómez-Guerra Umut Kutukoglu Joao Arthur Brunhara Alves-Barbosa Jorge Jaspersen Christian Acevedo Francisco Virgen-Gutiérrez Sumit agrawal Hugo Octaviano Duarte-Santos Chai Chu Ann Daniele Castellani Vineet Gahuar Department of Urology Hospital CovadongaCórdobaMéxico Department of Urology Hospital Universitario"Dr.José Eleuterio Gonzalez"MonterreyMéxico Department of Surgery S.H.Ho Urology CentrePrince of Wales HospitalThe Chinese University of Hong KongHong KongChina Department of Urology Marmara University School of MedicineIstanbulTurkey Department of Urology Hospital Central MilitarMéxico CityMéxico Department of Urology Hospital Israelita Albert EinsteinBP-a Beneficência Portuguesa de Sao PauloSao PauloBrazil Faculdade de Medicina do ABC Santo AndréBrazil Department of Urology University Surgical ClusterNational University HospitalSingaporeSingapore Department Urology Christian Medical CollegeVelloreTamilnadIndia Department Urology Hospital General de México"Dr.Eduardo Liceaga"México CityMéxico Department of Urology Hospital Regional de Alta Especialidad de la Peninsula de YucatánMéridaMéxico Department Urology Asian Institute of Nephrology and UrologyHyderabadIndia Department Urology King Abdulaziz National Guard HospitalRiyadhSaudi Arabia Division of Urology Department of SurgeryUniversity of MalayaKuala LumpurMalaysia Department of Urology Central Military HospitalMexico CityMexico National Academy of Medical Sciences Bir Hospital and B&B HospitalGwarko LalitpurNepal Department of Urology University Hospital Mohammed theⅥ^(th)of MarrakeshMarrakeshMorocco Department of Urology Federal University of ParanáSchool of MedicineHospital das ClínicasCuritibaBrazil Department of Urology Hospital Médica SurMexico CityMexico Department of Urology Hospital Yalgado Ouedraogo OuagadougaKadiogoBurkina Faso Department of Urology Hospital Das Clínicas da Universidade de Sao PauloSao PauloBrazil Department of Urology AIIMSBhubaneshwarIndia Department of Urology Hospital Municipal Dr.Moysés Deutsch(M'Boi Mirim)Sao PauloBrazil Department of Urology Azienda Ospedaliero-Universitaria Ospedali Riuniti di AnconaPolytechnic University of Le Marche RegionAnconaItaly Department of Minim

Background:Emphysematous pyelonephritis(EPN)is a necrotizing infection of the kidney and the surrounding tissues associated with considerable *** aimed to formulate a score that classifies the risk of mortality in patients with EPN at hospital *** and methods:Patients diagnosed with EPN between 2013 and 2020 were retrospectively *** from 15 centers(70%)were used to develop the scoring system,and data from 7 centers(30%)were used to validate *** and mułtivariable logistic regression analyses were performed to identify independent factors related to *** operating characteristic curve analysis was performed to construct the sconng system and calculate the risk of mortality.A standardized regression coefficient was used to quantify the discriminating power of each factor to convert the individual coefficients into *** area under the curve was used to quantify the scoring system *** 8-point scoring system for the mortality risk was created(range,0-7).Results:In total,570 patients were included(400 in the test group and 170 in the validation group).Independent predictors of mortality in the multivariable logistic regression were included in the scoring system:quick Sepsis-related Organ Failure Assessment score≥2(2 points),anemia,paranephric gas extension,leukocyte count>22,000/pL,thrombocytopenia,and hyperglycemia(1 point each).The mortality rate was<5%for scores≤3,83.3%for scores 6,and 100%for scores *** area under the Curve was 0.90(95%confidence interval,0.84-0.95)for test and 0.91(95%confidence interval,0.84-0.97)for the validation ***:Our score predicts the risk of mortality in patients with EPN at presentation and may help clinicians identify patients at a higher risk of death.

关键词： Emphysematous pyelonephritis Mortality Prognosis

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