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Journal of Life Sciences 2013年第8期7卷 820-826页

作者： Lucia Vieira Hoffmann paulo Augusto Vianna Barroso Jair Moises de sousa Flora Ismail Tibazarwa Embrapa Santo Anthonio de Goias 75375-000 Brazil Federal University of Campina Grande Patos Campus University Avenue Paraiba 58700-970 Brazil Department of Botany University of Dar es Salaam Dar Es Salaam 35060 Tanzania

Measuring fitness is essential for understanding the potential impacts of hybridisation between transgenic crops and their wild relatives. Transgenic CrylAc cotton Gossypium hirsutum and G. barbadense hybridise, the latter being valued as backyard cotton and an important genetic resource. G. barbadense was outcrossed to G. hirsutum containing the gene CrylAc and the isoline and the offspring evaluated for fitness as a measure of resistance to common pests and other growth parameters, Resistance to Pectinophora gossypiella and Alabama argillacea were greater in transgenic plants. Number of seeds per plant was higher in the F1 hybrids and G. hirsutum, F2 populations were intermediary; G. barbadense produced the least seeds per plant during the period of analysis. Anthesis of the first flower and opening of the first boll occurred earlier for G. hirsutum and Ft hybrids than F2; latest for G. barbadense. The observed-performance of resistance to the worms in the hybrids suggests that among FI and F2 populations transgenic hybrids may exhibit a competitive advantage over non-transgenic plants as a result of gene flow.

关键词： Biosafety pink bollworm cotton leaf worm gene flow.

Three-year follow-up in advanced pediatric keratoconus:thin corneas may not have pachymetry properly assessed after crosslinking

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International Journal of Ophthalmology(English edition) 2020年第10期13卷 1561-1566页

作者： Rosalia Antunes-Foschini Sidney Júlio Faria-e-sousa Hospital das Clínicas Medical School of Ribeirao PretoUniversity of Sao PauloRibeirao Preto 14049-900Brazil Department of Ophthalmology OtorhinolaryngologyHead and Neck SurgeryMedical School of Ribeirao PretoUniversity of Sao PauloRibeirao Preto 14049-900Brazil

AIM:To analyze the crosslinking(CXL)effects in pediatric keratoconus,and to identify the patients’corneal characteristics whose pachymetry could not be adequately evaluated by Scheimpflug method after ***:Consecutive pediatric patients with progressive keratoconus underwent CXL were ***-corrected visual acuity(BCVA)and spheric equivalent(SE)were measured before and after *** CXL,groups 1 and 2 were divided based on the posterior surface Pentacam quality specifications(QS):"OK"(Group 1)and"not OK"(Group 2).The mean(RmF and RmB)and minimum(RminF and RminB)radius of curvatures of the anterior and posterior corneal surfaces,and the thinnest pachymetry(Pmin)were measured preoperatively at 3,6,12,24,and 36 *** was ***:Twenty-six patients(14 men,mean age 14±1.8 y)and median Kmax of 59.9 D initially and 61.4 D preoperatively were *** was not different before and 24 mo after *** 2 statistically differed to group 1 in that SE was more myopic before and with no difference 24 mo after CXL;RmF and RmB were steeper and Pmin was thinner *** 2,in which pachymetric changes could not be adequately evaluated after surgery,presented with significant RmF flattening,a shift to hyperopia,and more haze after ***:Patients whose pachymetry could not be adequately evaluated after CXL had steeper and thinner corneas before *** predictive factors for impaired QS after CXL are RmF,RmB,and *** advanced keratoconus,alternative methods to analyze pachymetry and the posterior surface should be considered.

关键词： keratoconus cross-linking corneal pachymetry corneal topography corneal opacity

High-throughput phenotyping of two plant-size traits of Eucalyptus species using neural networks

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Journal of Forestry Research 2022年第2期33卷 591-599页

作者： Marcus Vinicius Vieira Borges Janielle de Oliveira Garcia Tays Silva Batista Alexsandra Nogueira Martins Silva Fabio Henrique Rojo Baio Carlos Antônio da Silva Junior Gileno Brito de Azevedo Glauce Taís de Oliveira sousa Azevedo Larissa Pereira Ribeiro Teodoro paulo Eduardo Teodoro Federal University of Mato Grosso Do Sul(UFMS) Chapadão Do SulMato Grosso Do Sul 79560000Brazil Department of Geography State University of Mato Grosso(UNEMAT)SinopMato Grosso 78555000Brazil

In forest modeling to estimate the volume of wood,artificial intelligence has been shown to be quite effi-cient,especially using artificial neural networks(ANNs).Here we tested whether diameter at breast height(DBH)and the total plant height(Ht)of eucalyptus can be pre-dicted at the stand level using spectral bands measured by an unmanned aerial vehicle(UAV)multispectral sensor and vegetation *** do so,using the data obtained by the UAV as input variables,we tested different configurations(number of hidden layers and number of neurons in each layer)of ANNs for predicting DBH and Ht at stand level for different Eucalyptus *** experimental design was randomized blocks with four replicates,with 20 trees in each experimental *** treatments comprised five Eucalyptus species(***,***,***,***-dis,and ***)and Corymbria *** and Ht for each plot at the stand level were measured seven times in separate overflights by the UAV,so that the multispectral sensor could obtain spectral bands to calculate vegetation indices(VIs).ANNs were then constructed using spectral bands and VIs as input layers,in addition to the categorical variable (species), to predict DBH and Ht at the stand level simultaneously. This report represents one of the first appli-cations of high-throughput phenotyping for plant size traits in Eucalyptus species. In general, ANNs containing three hidden layers gave better statistical performance (higher esti-mated r, lower estimated root mean squared error-RMSE) due to their greater capacity for self-learning. Among these ANNs, the best contained eight neurons in the first layer, seven in the second, and five in the third (8 − 7 − 5). The results reported here reveal the potential of using the gener-ated models to perform accurate forest inventories based on spectral bands and VIs obtained with a UAV multispectral sensor and ANNs, reducing labor and time.

关键词： Computational intelligence Diameter at breast height Forest inventory Remote sensing Vegetation indices

Higher Education For Sustainability:A Global Perspective

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Geography and Sustainability 2021年第2期2卷 99-106页

作者： IngaŽalėnienė paulo Pereira Mykolas Romeris University Ateities s.20VilniusLithuania Environmental Management Laboratory Mykolas Romeris UniversityAteities s.20VilniusLithuania

Higher education institutions have an essential role in *** are key agents in the education of future leaders that will contribute to the successful United Nations Sustainable Development Goals(SDGs)*** geography of SDGs this implementation is very heterogeneous,but it is clear that higher education institutions contribute decisively to creating a mindset that facilitates the dissemination of SDGs *** perspective paper analyses the impacts of higher education on sustainability and the challenges and barriers as-sociated with this *** education contributes decisively to the SDGs implementation,but especially to Goal 1(end poverty in all its forms everywhere),Goal 3(ensure healthy lives and promote well-being for all at all ages),Goal 5(gender equality),Goal 8(decent work and economic growth),Goal 12(responsible consumption and production),Goal 13(climate change)and Goal 16(peace,justice and strong institutions).As a transfor-mational agent,the higher education sector has a tremendous impact on students’habit and contribution to a prosperous ***,to establish the required change in education,sustainability principles need to be at the heart of higher institutions strategy(e.g.,curricula,modus operandi)and is key to be incorporated in the organisational *** by leading by example,the external influence in the society will be possible(e.g.,implementing SDGs key aspects such as gender quality,reduce waste reduction and energy consumption).For this to be a reality,different communication methods with students are needed(e.g.,different student academic levels).Nevertheless,critical challenges need to be tackled in the institutions inside and outside the institution environment,such as incorporating sustainability principles,political environment and stakeholders’interest.

关键词： Higher education institutions Sustainability Organisational culture Communication

Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis

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Hepatobiliary & Pancreatic Diseases International 2012年第5期11卷 549-552页

作者： paulo N Martins Patricia Sheiner Marcelo Facciuto Department of Surgery Transplant DivisionMassachusetts General HospitalHarvard Medical School Department of Surgery Division of Hepatobiliary Surgery and TransplantationNew York Medical College Division of Transplantation Mount Sinai Hospital

BACKGROUND: Xanthogranulomatous cholecystitis (XGC) is a destructive inflammatory disease of the gallbladder that can mimic gallbladder carcinoma. METHODS: We present the case of a 35-year-old Hispanic male complaining of right upper quadrant pain and jaundice for 2 months prior to admission. He denied a history of fever, nausea/ vomiting, and weight loss. The past medical history was relevant only for diabetes. He had no previous history of jaundice or previous operations. RESULTS: CA19-9 was slightly elevated (52 U/mL). Abdominal ultrasonography showed an irregular thickening of the gallbladder wall and no gallstones were detected. CT scan also revealed an irregular thickening of the wall of the gallbladder body suggestive of malignancy. At laparotomy, the mass was adherent to the duodenum and colon, and although the frozen section biopsy was negative, the intraoperative findings were suggestive of malignancy, and the patient underwent left liver trisegmentectomy, resection of the common bile duct and Roux-en-Y hepaticojejunostomy. Pathological examination unexpectedly revealed XGC without malignancy. CONCLUSIONS: Preoperative and intraoperative differential diagnosis of XGC from gallbladder carcinoma remains a challenge when it is associated with inflammatory involvement of surrounding tissues. Since gallbladder carcinoma and XGC may coexist, radical resection is justified when malignancy cannot be completely ruled out.

关键词： xanthogranulomatous cholecystitis gallbladder cancer obstructive cholestasis

Evolution of the 3.65-2.58 Ga Mairi Gneiss Complex,Brazil:Implications for growth of the continental crust in the São Francisco Craton

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Geoscience Frontiers 2022年第5期13卷 110-128页

作者： Igor de Camargo Moreira Elson Paiva Oliveira Daniel Francisco Martins de sousa Institute of Geosciences University of Campinas(UNICAMP)CampinasSPBrazil

The composition and formation of the Earth’s primitive continental crust and mantle differentiation are key issues to understand and reconstruct the geodynamic terrestrial evolution,especially during the ***,the scarcity of exposure to these rocks,the complexity of lithological relationships,and the high degree of superimposed deformation,especially with long-lived magmatism,make it difficult to study ancient *** this complexity,exposures of the Archean Mairi Gneiss Complex basement unit in the São Francisco Craton offer important information about the evolution of South America’s primitive ***,here we present field relationships,LA-ICP-SFMS zircon U-Pb ages,and LA-ICP-MCMS Lu-Hf isotope data for the recently identified Eoarchean to Neoarchean gneisses of the Mairi *** Complex is composed of massive and banded gneisses with mafic members ranging from dioritic to tonalitic,and felsic members ranging from TTG(Tonalite-Trondhjemite-Granodiorite)to granitic *** new data point to several magmatic episodes in the formation of the Mairi Gneiss Complex:Eoarchean(ca.3.65–3.60 Ga),early Paleoarchean(ca.3.55–3.52 Ga),middle-late Paleoarchean(ca.3.49–3.33 Ga)and Neoarchean(ca.2.74–2.58 Ga),with no records of Mesoarchean ***-Hf data unveiled a progressive evolution of mantle differentiation and crustal recycling over *** the Eoarchean,rocks are probably formed by the interaction between the pre-existing crust and juvenile contribution from chondritic to weakly depleted mantle sources,whereas mantle depletion played a role in the Paleoarchean,followed by greater differentiation of the crust with thickening and recycling in the middle–late Paleoarchean.A different stage of crustal growth and recycling dominated the Neoarchean,probably owing to the thickening of the continental crust by collision,continental arc growth,and mantle differentiation.

关键词： São Francisco Craton Mairi Gneiss Complex Primitive continental crust Zircon U-Pb dating Lu-Hf isotope geochemistry

The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates

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Cellular & Molecular Immunology 2018年第5期15卷 421-427页

作者： Eslam Mohamed Amir A.Al-Khami paulo C.Rodriguez lee moffitt cancer center and research institute 12902 magnolia dr.mrc-annex 2ndtampafl 33612usa stanley s.scott cancer center louisiana state university health sciences centernew orleansla 70112usa

Malignant cells upregulate distinct energy metabolism programs that support their proliferation,migration,and adaptation to the stressful tumor microenvironment(TME).Additionally,this exaggerated metabolic activity allows cancer cells to hijack essential nutrients and outcompete neighboring infiltrating immune cells,thereby impairing antitumor *** recent years,there has been great interest in the field to understand the tumor-induced energy metabolism signals that regulate the function of immune cells in individuals with ***,it is now well accepted that uncovering the mechanisms that instruct the metabolic behavior of cancer cells and tumor-associated immune cells is an indispensable strategy for the development of new approaches to overcome immune suppression in ***,in this minireview,we briefly discuss the interaction between particular metabolic signaling pathways and immunosuppressive activity in different subsets of myeloid cells within the ***,we illustrate potential central mechanisms controlling the metabolic reprogramming of myeloid cells in response to tumor-derived factors.

关键词： Tumor microenvironment metabolic reprogramming immune suppression myeloid cells

Temporal decay of the catalytic oxidation of methane over palladium supported on silica

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Science China Chemistry 2013年第11期56卷 1601-1607页

作者： CORTS Joaquín VALENCIA Eliana PINEDA Marcelo ARAYA paulo Departamento de Ingeniería Química y Biotecnología Universidad de Chile Departamento de Ciencia de Materiales Universidad de Chile

The temporal decay of the oxidation of methane(CH4-O2reaction)over palladium supported on silica is determined experimentally at different temperatures,comparing the results with those of various classical models which show the behavior of the adsorbed phase as the cause of the *** effect is visualized through Monte Carlo simulations of the CH4-O2reaction on a mixed lattice whose partial poisoning,due to the configuration of the OH groups on the surface of the adsorbate,is translated into a gradual decay of the reaction’s activity.

关键词： catalytic CH4-O2 reaction surface heterogeneity in superficial reaction Monte Carlo simulation superficial catalyticreaction CH4-O2 reaction over palladium

Structural metamaterials with negative mechanical/thermomechanical indices: A review

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Progress in Natural Science:Materials International 2021年第6期31卷 801-808页

作者： Jo?o O.Cardoso Jo?o paulo Borges Alexandre Velhinho CENIMAT/i3N Departamento de Ciência dos Materiais Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa

Structural metamaterials presenting negative values of one or more mechanical and thermomechanical indices–namely the Poisson's ratio, the linear compressibility, and the coefficient of thermal expansion – are the promising candidates to the applications in many fields, ranging from precision mechanics to biomedical devices or energy absorption. Although scattered mentions may be found in the literature since the late eighties of 20th century, the systematic research efforts concerning these materials became effective much later. The present work is to review the main scientific contributions to the topic in the last five years. This paper first deals with those metamaterials showing a single negative index, and then proceeds to analyze the much less frequent instances of coupled negative indices, with emphasis on the so-called anepectic case, which exhibits an unusual thermomechanical response.

关键词： Mechanical and thermomechanical metamaterials Auxetic Anepectic Negative Poisson's ratio Negative thermal expansion Negative linear compressibility

Applied and Environmental Chemistry of Animal Manure:A Review

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Pedosphere 2016年第6期26卷 779-816页

作者： Zhongqi HE paulo H.PAGLIARI Heidi M.WALDRIP USDA-ARS Southern Regional Research Center Department of Soil Waterand ClimateUniversity of MinnesotaSouthwest Research and Outreach Center USDA-ARS Conservation and Production Research Laboratory

Animal manure consists of predominantly urine and feces, but also may contain bedding materials, dropped feed, scurf, and other farming wastes. Manure is typically applied to soils as fertilizer for agricultural production. The estimated amount of manure produced in 12 major livestock-producing countries is 9 × 10^9 Mg of manure annually. Manure is rich in plant nutrients. However, manure is also considered as an environmental pollutant when it is over-applied to cropland or following runoff into surface water. Manure can also influence global climate change via emissions of methane （CH4） and nitrous oxide （N2O）. Thus, increased and updated knowledge of applied and environmental chemistry of animal manure is needed to shed light on the research and development of animal manure utilization and minimization of its adverse environmental concerns. The advances in basic and applied studies of manure major components, organic matter, phosphorus, and nitrogen, primarily related to US livestock production are summarized in this review. Detailed focus was placed on three notable challenges for future manure research： 1） soil application of animal manure, 2） manure phytate phosphorus, and 3） manure nitrogen availability. This review may contribute to the global effort in sustainable and environmentally sound agriculture by stimulating new ideas and directions in animal manure research, and promoting application of knowledge and insight derived from manure research into improved manure management strategies.

关键词： environmental pollutant fertilizer nitrogen availability organic matter phosphorus phytate plant nutrients