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Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2024年第2期13卷 145-159页

作者： paulo Ricardo Prado Nunes Pamela Castro-e-souza Anselmo Alves de Oliveira Bruno de Freitas Camilo Gislaine Cristina-souza Lucio Marques Vieira-souza marcelo Augusto da Silva Carneiro department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exercise and Nutrition Research Group(GPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical Exercise Study and Research Group(GEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in PubMed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(CG) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(Grading of Recommendations,Assessment,development,and Evaluation(GRAde)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;GRAde:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to CG,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein Fat mass Lipid profile Menopause Strength training

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Variation of Morpho-Agronomic and Biomass Quality Traits in Elephant Grass for Energy Purposes According to Nitrogen Levels

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American Journal of Plant Sciences 2015年第11期6卷 1685-1696页

作者： Erik da Silva Oliveira Rogério Figueiredo Daher Niraldo José Ponciano Geraldo de Amaral Gravina José Augusto de Almeida Sant’ana Romildo Domingos Gottardo Bruna Rafaela da Silva Menezes paulo marcelo de souza Cláudio Luiz Melo de souza Veronica Brito da Silva Avelino dos Santos Rocha Antonio Alonso Cecon Novo Universidade Estadual do Norte Fluminense Darcy Ribeiro Campos dos GoytacazesRJBrazil Instituto Federal do Espírito Santo Campus of AlegreAlegreESBrazil Universidade Federal Rural do Rio de Janeiro SeropédicaRJBrazil

Elephant grass is a tropical forage plant widely spread in Brazil, used mainly in the livestock sector and in cattle feeding. Because of its high productivity and photosynthetic capacity, this culture has also been considered an alternative source of renewable energy. Six clones of elephant grass (Pennisetum purpureum Schum.) were evaluated under five levels of nitrogen fertilization (100, 200, 400, 800, and 1600 kg·N·ha-1), in a randomized-block design with a split-plot arrangement with three replicates, from April 2010 to december 2012, in the city of Campos dos Goytacazes— RJ, Brazil. The objective was to obtain estimates of variation in morpho-agronomic traits and biomass quality. We observed that genotypes Cameroon-Piracicaba and Gua?u I/Z2 have great potential to be used, with maximum dry matter yields of 60.97 and 44.10 t·ha-1 per cut for energy purposes among the studied genotypes.

关键词： Nitrogen Fertilization Alternative Energy Energy Biomass Dry Matter Yield Pennisetum purpureum Schum

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Physico-chemical characterization of acid base disorders in patients with COVID-19:A cohort study

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World Journal of Nephrology 2024年第2期13卷 16-23页

作者： Sergio Pinto de souza Juliana R Caldas marcelo Barreto Lopes marcelo Augusto Duarte Silveira Fernanda Oliveira Coelho Igor Oliveira Queiroz Pedro Domingues Cury Rogério da Hora Passos department of Nephrology Hospital São RafaelSalvadorBA 41253190Brazil department of Nephrology D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Faculty of Medicine Escola Bahiana de Medicina e Saúde Pública-EBMSPSalvadorBA 40290000Brazil department of Intensive Care D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Hospital São Rafael D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil department of Intensive Care Unit Hospital Israelita Albert EinsteinSao PauloSP 05652900Brazil

BACKGROUND Acid-base imbalance has been poorly described in patients with coronavirus disease 2019(COVID-19).Study by the quantitative acid-base approach may be able to account for minor changes in ion distribution that may have been over-looked using traditional acid-base analysis *** a cohort of critically ill COVID-19 patients,we looked for an association between metabolic acidosis surrogates and worse clinical outcomes,such as mortality,renal dialysis,and length of hospital *** To describe the acid-base disorders of critically ill COVID-19 patients using Stewart’s approach,associating its variables with poor *** This study pertained to a retrospective cohort comprised of adult patients who experienced an intensive care unit stay exceeding 4 days and who were diagnosed with severe acute respiratory syndrome coronavirus 2 infection through a positive polymerase chain reaction analysis of a nasal swab and typical pulmonary involvement observed in chest computed tomography *** and clinical data were obtained from electronic *** variables were compared using Fisher’s exact *** data were presented as median and interquartile *** Mann-Whitney U test was used for *** In total,211 patients were *** mortality rate was 13.7%.Overall,149 patients(70.6%)presented with alkalosis,28 patients(13.3%)had acidosis,and the remaining 34 patients(16.2%)had a normal arterial pondus *** those presenting with acidosis,most had a low apparent strong ion difference(SID)(20 patients,9.5%).Within the group with alkalosis,128 patients(61.0%)had respiratory *** non-survivors were older,had more comorbidities,and had higher Charlson’s and simplified acute physiology score *** did not find severe acid-base imbalance in this *** analyzed Stewart’s variables(effective SID,apparent SID,and strong ion gap and the effect of albumin,lactate,phosphorus,and chloride)were not d

关键词： COVID-19 Physicochemical approach Acid-base status Critically ill patients Acute respiratory syndrome

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The effect of abiotic stresses on plant C:N:P homeostasis and their mitigation by silicon

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The Crop Journal 2024年第2期12卷 340-353页

作者： Milton Garcia Costa Renato de Mello Prado Luiz Fabiano Palaretti Jonas Pereira de souza Júnior department of Agricultural Production Science School of Agricultural and Veterinarian SciencesSão Paulo State UniversityJaboticabalBrazil

In crop plants, various environmental stresses affect the balance of carbon, nitrogen, and phosphorus(C:N:P), leading to biochemical and physiological alterations and reductions in yield. Silicon(Si) is a beneficial element that alleviates plant stress. Most studies involving silicon have focused on physiological responses, such as improvements in photosynthetic processes, water use efficiency, and antioxidant defense systems. But recent research suggests that stressed plants facing either limited or excessive resources(water, light, nutrients, and toxic elements), strategically employ Si to maintain C:N:P homeostasis, thereby minimizing biomass losses. Understanding the role of Si in mitigating the impact of abiotic stresses on plants by regulating C:N:P homeostasis holds great potential for advancing sustainable agricultural practices in crop production. This review presents recent advances in characterizing the influence of environmental stresses on C:N:P homeostasis, as well as the role of Si in preserving C:N:P equilibrium and attenuating biological damage associated with abiotic stress. It underscores the beneficial effects of Si in sustaining C:N:P homeostasis and increasing yield via improved nutritional efficiency and stress mitigation.

关键词： Nutritional stoichiometry Elemental stoichiometry Beneficial element Environmental stresses Nutritional efficiency Carbon use efficiency Agricultural sustainability

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A remote sensing approach to estimate the load bearing capacity of soil

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Information Processing in Agriculture 2024年第1期11卷 109-116页

作者： Italo Rômulo Mendes de souza Edson Eyji Sano Renato Paiva de Lima Anderson Rodrigo da Silva Statistics and Geoprocessing Laboratory Instituto Federal GoianoGeraldo Silva Nascimento RoadKm 2.575790-000 UrutaíGoiásBrazil Embrapa Cerrados BR-020 RoadKm 18Mailbox 0822373310-970 PlanaltinaDFBrazil department of Soil Science ‘Luiz de Queiroz’College of AgricultureUniversity of São PauloAv.Pádua Dias235-AgronomiaPiracicabaSP 13418-900Brazil

Preconsolidation pressure(σp)of soil can be considered as an indicator of the Load Bearing Capacity(LBC),which is the tolerated surface pressure before compaction,often caused by the traffic of agricultural *** this pioneering study,a remote sensing approach was introduced to estimate LBC throughσp from soils of the“Rio Preto”Hydrographic Basin,Bahia State,Brazil,in a monthly time lapse from 2016 to ***,σp is measured by a laborious and time demanding laboratory analysis,making it unfeasible to map large *** innovative methodology of this work consists of combining active–passive satellite data on soil moisture and pedotransfer functions of clay content and water matric potential to obtain geo-located estimates ofσ*** were analysed under different classes of soil use,land cover and slope;95%confidence intervals were built for the time series of mean values of LBC for each *** overall seasonal variation in LBC estimates is similar in areas with annual crops,grasslands and natural vegetation,and flat areas are less affected by soil moisture variations over the year(between seasons).LBC decreased,in general,at about 0.5%a year in flat ***,these areas demand attention,since they occupy 86%of the Basin and are mostly subjected to agricultural soil management and surface pressure by heavy machinery.

关键词： Soil compaction SMAP Preconsolidation stress Brazilian Cerrado

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Starch Orodispersible Film Loaded with Melatonin for Human Supplementation

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Journal of Renewable Materials 2024年第7期12卷 1343-1354页

作者： Fabio Tamanini Tatiane Zucchini de souza Creusa Sayuri Tahara Amaral Antônio JoséFelix Carvalho Eliane Trovatti department of Health and Biological Sciences University of Araraquara(UNIARA)São Paulo14801-340Brazil department of Materials Engineering São Carlos School of EngineeringUniversity of São PauloSão Paulo13563-120Brazil

An innovative pharmaceutical form for administering melatonin,based on starch orodispersibleﬁlm(ODF),was designed and *** composition of the ODF included starch as the polymer matrix,the active drug melatonin,and a ***,a natural hormone produced by the pineal gland in the brain,can be absorbed by passive diffusion across the mucous membrane,resulting in improved bioavailability when compared to conventional oral *** study shows a simple and efﬁcient method for preparing melatonin-loaded orodispersibleﬁlms with a physically stable and commercially viable matrix,suitable for use in the pharmaceutical ***ﬁlms were prepared by treating the starch with microwave irradiation,followed by plasticization with glycerol,melatonin loading and drying by solvent *** tests showed theﬁlms’robustness,with a modulus of approximately 97 MPa,indicating good handling *** uptake analysis showed fast water absorption,reaching about 150%within 2 min,indicating its fast oral disintegration *** tests in artiﬁcial saliva and dissolution studies indicated the release of the drug in min-utes,indicating the potential properties of theﬁlm for oral drug *** the best of our knowledge,there is no melatonin ODF based on starch described in the literature.

关键词： Starch orodispersibleﬁlm melatonin drug delivery

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MicroRNAs in inflammatory bowel disease:What do we know and what can we expect?

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World Journal of Gastroenterology 2024年第16期30卷 2184-2190页

作者： Ellen Cristina souza de Oliveira Ana Elisa Valencise Quaglio Thais Gagno Grillo Luiz Claudio Di Stasi Ligia Yukie Sassaki department of Internal Medicine Medical SchoolSão Paulo State University(Unesp)Botucatu 18618-686São PauloBrazil Verum Ingredients Botucatu Technology ParkBotucatu 18605-525São PauloBrazil department of Biophysics and Pharmacology Institute of BiosciencesSão Paulo State University(Unesp)Botucatu 18618-689São PauloBrazil

MicroRNAs(miRNAs),small non-coding RNAs composed of 18–24 nucleotides,are potent regulators of gene expression,contributing to the regulation of more than 30%of protein-coding *** that miRNAs are regulators of inflammatory pathways and the differentiation of intestinal epithelial cells,there is an interest in exploring their importance in inflammatory bowel disease(IBD).IBD is a chronic and multifactorial disease of the gastrointestinal tract;the main forms are Crohn's disease and ulcerative *** studies have investigated the dysregulated expression of miRNAs in IBD,demonstrating their important roles as regulators and potential biomarkers of this *** editorial presents what is known and what is expected regarding miRNAs in *** the important regulatory roles of miRNAs in IBD are clearly established,biomarkers for IBD that can be applied in clinical practice are lacking,emphasizing the importance of further *** regarding the influence of miRNAs on the inflammatory process and the exploration of their role in gene regulation are expected to provide a basis for the use of miRNAs not only as potent biomarkers in IBD but also as therapeutic targets for the control of inflammatory processes in personalized medicine.

关键词： MicroRNAs Inflammatory bowel disease Crohn’s disease Ulcerative colitis Biomarker Therapy

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Changes in calcium accumulation and utilization efficiency and their impact on recycling,immobilization,and export across the oil palm cycle

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Oil Crop Science 2024年第3期9卷 143-150页

作者： Ismael de Jesus Matos Viégas Luma Castro de souza Eric Victor de Oliveira Ferreira Milton Garcia Costa Glauco André dos Santos Nogueira Vitor Resende do Nascimento Candido Ferreira de Oliveira Neto Capanema Campus Federal Rural University of the Amazon(UFRA)Av.Barao de CapanemaCaixa D'agua5514-6434ParaBrazil Center of Agricultural and Environmental Sciences Federal University of Maranhao(UFMA)ChapadinhaBR-222km 04SNBoa Vista65500000MaranhaoBrazilc Capitao Poço Campus Federal Rural University of the Amazon(UFRA)Tv.Pau AmareloS/n-Vila Nova68650-000Capitao PoçoParaBrazil department of Soil Science Sao Paulo State University(Unesp)School of Agricultural and Veterinarian SciencesJaboticabalVia de Acesso Prof.Paulo Donato CastelaneCastellane-S/N-Vila Industrial14884-900Sao PauloBrazil Institute of Agricultural Sciences(ICA) Federal Rural University of the Amazon(UFRA)Estr.Principal da Ufra2150Curio-Utinga66077-580BelemParaBrazil

Effective calcium(Ca)management is crucial for optimizing oil palm cultivation and enhancing crop *** study aimed to gain insights into the dynamics of Ca concentration,accumulation,exportation,immobilization,and recycling in various oil palm organs relative to plant *** experiment was conducted at the Agropalma enterprise site in the northeastern region of Para State,Brazil,evaluating seven plant age treatments:2,3,4,5,6,7,and 8 years *** a completely randomized design with four *** results demonstrated an age-related increase in Ca concentration in petioles,rachis,arrows,male inflorescences,peduncles,and ***,Ca accumulation exhibited an upward trend in all organs with progressing plant ***,the study revealed an enhanced Ca use efficiency across all plant organs in correlation with the age of oil palm *** findings underscore the dynamic nutritional demands of oil palm,influencing Ca immobilization,cycling,and export throughout its developmental stages.

关键词： Elaeis guineensis Jacq Ca cycling Ca export Ca immobilization Ca use efficiency Plant nutrition Amazon

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Unsuccessful tuberculosis treatment outcomes across Brazil's geographical landscape before and during the COVID-19 pandemic:are we truly advancing toward the sustainable development/end TB goal?

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Infectious Diseases of Poverty 2024年第1期13卷 105-106页

作者： Reginaldo Bazon Vaz Tavares Thais Zamboni Berra Yan Mathias Alves Marcela Antunes Paschoal Popolin Antonio Carlos Vieira Ramos Ariela Fehr Tartaro Clara Ferreira de souza Ricardo Alexandre Arcencic department of Maternal-Infant and Public Health Nursing University of São Paulo at Ribeirão Preto College of Nursing (USP/RPCN) Ribeirão Preto São Paulo Brazil Federal University of Tocantins Palmas Campus (FUT) Palmas Brazil State University of Minas Gerais Passos Campus (SUMG) Passos Brazil

Background Tuberculosis is one of the most significant infectious diseases for global public *** reallocation of healthcare resources and the restrictions imposed by the COVID-19 pandemic have hindered access to TB diag-nosis and *** in unfavorable outcomes of the disease have been observed in *** objective of this study was to analyze the spatial distribution of unfavorable TB treatment outcomes in Brazil before and during the *** An ecological study with spatial analysis was conducted with all 5569 municipalities in *** reported cases of tuberculosis between January 2010 and december 2021,as well as reported cases of COVID-19 from Febru-ary 2020 to december 2021,were *** outcomes studied encompass loss to follow-up,drug-resistant tuber-culosis,and *** Getis Ord GI*technique was employed to assess spatial association,and the Kernel density estimator was used to identify areas with concentrated increases or decreases in *** Local Moran's/was used to examine the spatial association between outcomes and cOVID-19 *** study was approved by the Research Ethics Committee of Ribeirao Preto Nursing School,University of Sao *** There were 134,394 cases of loss to follow-up,10,270 cases of drug resistance,and 37,863 *** of high and low values were identified for all three outcomes,indicating significant changes in the spatial distribu-tion *** in concentrations were observed for lost to follow-up cases in the Southeast,while reductions occurred in the Northeast,South,and ***-resistant tuberculosis experienced an increase in the Southern and Southeastern regions and a decrease in the Northeast and ***-related deaths showed notable concentra-tions in the Midwest,Northeast,South,and *** was an increase in high occurrence clusters for deaths after 2020 and 2021 in the *** The pandemic has brought additional chal

关键词： Tuberculosis COVID-19 Spatial analysis Ecological studies

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Resilience-Oriented Approach to the Control of Ventricular Assist devices

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Journal of Biomedical Science and Engineering 2024年第8期17卷 137-156页

作者： Jônatas Cerqueira Dias Jeferson Cerqueira Dias Milena Victoria de Azevedo souza Diolino José dos Santos Filho department of Mechatronic Engineering and Mechanical Systems Universidade de So Paulo (USP) So Paulo Brazil department of Mechatronic Engineering and Mechanical Systems Universidade de So Paulo (USP) So Paulo Brazil department of Biomedical Technology Faculdade de Tecnologia Prefeito Hirant Sanazar (FATEC OSASCO) Osasco Brazil

Context: Advanced heart failure (AHF) poses a global challenge, where heart transplantation is a treatment option but limited by donor scarcity. Proposal: This study aims to enhance the performance of ventricular assist devices (VADs) in the face of adverse events (AEs) using a resilience-based approach. The objective is to develop a method for integrating resilience attributes into VAD control systems, employing dynamic risk analysis and control strategies. Results: The outcomes include a resilient control architecture enabling anticipatory, regenerative, and degenerative actions in response to AEs. A method of applied resilience (MAR) based on dynamic risk management and resilience attribute analysis was proposed. Conclusion: Dynamic integration between medical and technical teams allows continuous adaptation of control systems to meet patient needs over time, improving reliability, safety, and effectiveness of VADs, with potential positive impact on the health of heart failure patients.

关键词： Heart Failure Ventricular Assist devices Resilience Dynamic Control

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