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Mountain invasions on the way:are there climatic constraints for the expansion of alien woody species along an elevation gradient in Argentina?

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Journal of Plant Ecology 2016年第4期9卷 380-392页

作者： paula a.tecco Ana I.Pais-Bosch Guillermo Funes paula I.Marcora Sebastián R.Zeballos Marcelo Cabido Carlos Urcelay Instituto Multidisciplinario de BiologíaVegetal(CONICET-UNC) Velez Sarsfield 1611.Córdoba 5000Argentina Facultad de Ciencias Exactas Físicas y Naturales Universidad Nacional de CórdobaVelez Sarsfield 299Córdoba 5000Argentina Facultad de Ciencias Agrarias Universidad Nacional de Catamarca.Maestro Quiroga 51Catamarca 4700Argentina

Aims Increasing evidence worldwide indicates that high mountain regions are not immune to invasion by alien ***,we aimed to address whether three major woody invaders of low-mountain areas are constrained to lower altitudes due to climatic restrictions or just by low propagule *** hypothesize that the increasing climatic harshness towards higher altitudes restricts seedling establishment and survival of these woody invaders and thus their potential for altitudinal *** The study was carried out in the Sierras Grandes Mountains,Córdoba,central Argentina(32°50′S,64°90′W).We addressed the hypothesis with an experimental approach,dissociating the effect of the environmental gradient from that of propagule pressure,by discarding the influence of seed *** translocated seeds of Gleditsia triacanthos L.,Ligustrum lucidum *** Pyracantha angustifolia(Franch.)*** the altitudinal gradient(from 900 to 2700 m asl).Seven sites were selected along the altitudinal gradient,spaced every 200-400 *** plots(4×4 m)were selected within each altitudinal site and excluded from livestock;100 seeds of each species were sown within each plot(6300 seeds in total).Seedling emergence and survival was monitored during two growing seasons and soil temperature and moisture was recorded as *** field experiment was complemented with lab *** Findings Climate along this altitudinal gradient might be least restrictive at mid elevations,as a result of the intersection between opposite soil temperature and moisture *** seeds germinated along the whole altitudinal gradient and seedlings successfully established and over-wintered well above their current altitudinal distribution(up to 2200 m for Ligustrum and 2400 m for Gleditsia and Pyracantha).Additional lab assays confirmed field patterns and gave some insights into contrasting regeneration strategies between these invaders that might help to overcome stochastic e

关键词： altitudinal gradient exotic species Gleditsia triacanthos Ligustrum lucidum Pyracantha angustifolia seedling establishment

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E2F transcription factors and their complementary roles during DNA damage responses

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Molecular Plant 2023年第9期16卷 1373-1375页

作者： paula Casati Centro de Estudios Fotosinteticos y Bioquimicos(CEFOBl) Universidad Nacional de RosarioSuipacha 5312000 RosarioArgentina

E2F transcription factors(TF)comprise a family of proteins that regulate the expression of genes required for S-phase progression,among *** genome encodes six E2F TFs(E2FA–F),which are classified as typical(E2FA–C)and atypical(E2FD–F)depending on their ability to interact with two DP interaction proteins(DPa and DPb)(Sablowski and Gutierrez,2022).While E2FA–C need to heterodimerize with either DPa or DPb to function,E2FD–F act independently of DP ***,the retinoblastoma-related1(RBR1)protein also binds and inhibits the typical E2F/DP TF complexes when bound to the promoter of genes,repressing their expression in the absence of a signal to enter a new cell *** general,E2FA and E2FB are considered transcriptional activators,while E2FC is generally considered a repressor of cell proliferation(Sablowski and Gutierrez,2022).In addition,it is well documented that E2FB at least,and probably E2FA,can also stimulate the G2/M transition.

关键词： damage E2F complementary

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3D City Models as a Visual Support Tool for the Analysis of Buildings Seismic Vulnerability: The Case of Lisbon

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International Journal of Disaster Risk Science 2017年第3期8卷 308-325页

作者： paula Redweik paula Teves-Costa Inês Vilas-Boas Teresa Santos Instituto Dom Luiz Faculdade de CiênciasUniversidade de Lisboa ESRI Portugal CICS.NOVA–Centro Interdisciplinar de Ciências Sociais Faculdade de Ciências Sociais e HumanasUniversidade Nova de Lisboa

3D city models associate a database of a city to a rigorous geospatial representation that is close to the visible reality by combining appearance, geometry, and semantics. As such, these models may include tools that convey attribute analysis, not only at the statistical level but also in terms of visual appearance of the objects, thus allowing the generation of new knowledge about a phenomenon or its effects. Lisbon is a city with a moderate level of seismic risk, and has been hit in the past by strong earthquakes. Several seismic vulnerability studies of buildings have been carried out in Lisbon. These studies generate different scenarios that consider the magnitude and source location of potential earthquakes. The results of these studies were presented as maps obtained from crossing information contained in 2D layers and presented in a GIS environment. In the present study a seismic vulnerability assessment of Lisbon's buildings held in 2D is extended to the third dimension, which refines the resolution and the set of parameters and explores the gains of spatial analysis in 3D representations. The numerous parameters that contribute to assess seismic vulnerability of buildings may be analyzed individually or simultaneously as well as in multiple seismic scenarios. Although covering all residential buildings in Lisbon, the application of the 3Dcity model is demonstrated with more detail in three pilot areas.

关键词： 3D-GIS 3D models Building vulnerability Lisbon Seismic scenarios

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Striatum-specific mechanisms regulate neuronal cell cycle re-entry:the choice between life and death

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Neural Regeneration Research 2023年第3期18卷 523-524页

作者： paula Dietrich Ioannis Dragatsis Department of Physiology The University of TennesseeHealth Science CenterMemphisTNUSA

Mitochondria dysfunction occurs in the aging brain as well as in several neurodegenerative disorders and predisposes neuronal cells to enhanced sensitivity to *** particular,defects in any of the mitochondria respiratory chain complexes lead to impaired adenosine triphosphate production resulting in diseases that often affect the central nervous *** instance,innate deficits in succinate dehydrogenase(SDH)mitochondria respiratory chain complex II activity caused by genetic mutations in SDH subunits lead to early-onset neurodegeneration(Jain-Ghai et al.,2013),while several adult-onset genetic neurodegenerative disorders are associated with variable levels of complex II deficiency in the central nervous system(Túnez et al.,2010).Also,chemically induced complex II deficiency leads to neurodegeneration.

关键词： SDH impaired cycle

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Forecasting patient demand at urgent care clinics using explainable machine learning

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CAAI Transactions on Intelligence Technology 2023年第3期8卷 712-733页

作者： Teo Susnjak paula Maddigan School of Mathematical and Computational Sciences Massey UniversityAucklandNew Zealand

Urgent care clinics and emergency departments around the world periodically suffer from extended wait times beyond patient expectations due to surges in patient *** delays arising from inadequate staffing levels during these periods have been linked with adverse clinical *** research into forecasting patient flows has mostly used statistical *** studies have also predominately focussed on short‐term forecasts,which have limited practicality for the resourcing of medical *** study joins an emerging body of work which seeks to explore the potential of machine learning algorithms to generate accurate forecasts of patient *** research uses datasets covering 10 years from two large urgent care clinics to develop long‐term patient flow forecasts up to one quarter ahead using a range of state‐of‐the‐art algo-rithms.A distinctive feature of this study is the use of eXplainable Artificial Intelligence(XAI)tools like Shapely and LIME that enable an in‐depth analysis of the behaviour of the models,which would otherwise be *** analysis tools enabled us to explore the ability of the models to adapt to the volatility in patient demand during the COVID‐19 pandemic lockdowns and to identify the most impactful variables,resulting in valuable insights into their *** results showed that a novel combination of advanced univariate models like Prophet as well as gradient boosting,into an ensemble,delivered the most accurate and consistent solutions on *** approach generated improvements in the range of 16%-30%over the existing in‐house methods for esti-mating the daily patient flows 90 days ahead.

关键词： data mining explainable AI forecasting machine learning patient flow urgent care clinics

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Impact of weather conditions and building design on contaminant infiltration from crawl spaces in Swedish schools-Numerical modeling using Monte Carlo method

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Building Simulation 2022年第5期15卷 845-858页

作者： Fredrik Domhagen paula Wahlgren Carl-Eric Hagentoft Department for Architecture and Civil Engineering Division of Building TechnologyChalmers University of TechnologySE-41296GothenburgSweden

Some Swedish school buildings built in the 1960s and 1970s experience indoor air quality problems,where the contaminants are suspected to come from the crawl space underneath the *** poor indoor air quality causes discomfort among pupils and *** an exhaust fan to maintain a negative pressure difference in the crawl space relative to indoors or increasing the ventilation in the classroom are two examples of common measures taken to improve the indoor air ***,these measures are not always effective,and sometimes the school building has to be *** relation between pressure distribution,contaminant concentration in the classroom,outdoor temperature,wind,mechanical ventilation,and air leakage distribution is complex.A better understanding of these relations is crucial for making decisions on the most efficient measure to improve the indoor air *** this paper,a model for contaminant infiltration from the crawl space is used together with the Monte Carlo method to study these *** are performed for several cases where different building shapes,building orientations,shielding conditions,and geographical locations are *** show,for example,that for a building with an imbalanced ventilation system,air is leaking from the crawl space to the classroom for the majority of cases and that concentration levels in the classroom are usually the highest during mild and calm days.

关键词： airtightness air permeability Monte Carlo method infiltration model crawl space indoor air quality

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Numerical Approach of a Coupled Pressure-Saturation Model Describing Oil-Water Flow in Porous Media

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Communications on Applied Mathematics and Computation 2023年第2期5卷 946-964页

作者： paula Luna Arturo Hidalgo ISIS Neutron and Muon Source Rutherford Appleton LaboratoryDidcot OX110QXUK Departamento de Ingeniería Geológica y Minera Escuela Técnica Superior de Ingenieros de Minas y EnergíaCenter for Computational SimulationUniversidad Politécnica de MadridRíos Rosas2128003 MadridSpain

Two-phase flow in porous media is a very active field of research,due to its important applications in groundwater pollution,CO_(2)sequestration,or oil and gas production from petroleum reservoirs,just to name a few of *** flow equations,which make use of Darcy's law,for describing the movement of two immiscible fluids in a porous medium,are among the most relevant mathematical models in reservoir *** work aims to solve a fractional flow model formed by an elliptic equation,representing the spatial distribution of the pressure,and a hyperbolic equation describing the space-time evolution of water *** numerical solution of the elliptic part is obtained using a finite-element(FE)scheme,while the hyperbolic equation is solved by means of two dif-ferent numerical approaches,both in the finite-volume(FV)*** is based on a monotonic upstream-centered scheme for conservation laws(MUSCL)-Hancock scheme,whereas the other makes use of a weighted essentially non-oscillatory(ENO)*** both cases,a first-order centered(FORCE)-αnumerical scheme is applied for inter-cell flux reconstruction,which constitutes a new contribution in the field of fractional flow models describing oil-water movement.A relevant feature of this work is the study of the effect of the parameterαon the numerical solution of the models *** also show that,in the FORCE-αmethod,when the parameterαincreases,the errors diminish and the order of accuracy is more properly attained,as verified using a manufactured solution technique.

关键词： Two-phase flow Reservoir simulation Porous media FORCE-α Finite volume

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Identification of Pu and U isotopic composition and its applications in environmental and CBRN research

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Defence Technology（防务技术） 2021年第3期17卷 728-740页

作者： Susanna Salminen-Paatero paula Vanninen Jussi Paatero Department of Chemistry RadiochemistryP.O.Box 55FI-00014University of HelsinkiFinland VERIFIN-Finnish Institute for the Verification of the Chemical Weapons Convention Department of ChemistryP.O.Box 55FI-00014University of HelsinkiFinland Finnish Meteorological Institute Observation ServicesP.O.Box 503FI-00101HelsinkiFinland

This paper describes the most common presently used methods for detecting uranium and plutonium isotopes after their introduction to environment. Known isotope ratios of U and Pu in different nuclear events are important tool for characterizing the sources of nuclear material. Detection techniques both in field and in laboratory are presented, as well as different models that can be used for identifying the origin and age of the nuclear material. Identification of the source of nuclear material in environmental samples is needed for estimating the quality and quantity of the nuclear hazard. This information is essential in risk assessment and crisis management, in chemical, biological, radiological and nuclear(CBRN) research after e.g. a terrorist attack, in radioecology and environmental radioactivity research.

关键词： CBRN Nuclear contamination Plutonium isotope ratios Uranium isotope ratios Nuclear fingerprinting Nuclear particle

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Myelin positron emission tomography(PET) imaging in multiple sclerosis

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Neural Regeneration Research 2020年第10期15卷 1842-1843页

作者： Daniele de paula Faria Laboratory of Nuclear Medicine (LIM-43) Departamento de Radiologia e Oncologia Faculdade de Medicina Universidade de Sao Paulo

Multiple sclerosis(MS)is a neurodegenerative disease characterized by inflammation and *** are focused on encountering remyelination therapies that can be applied to delaying,or even decreasing,the motor and cognitive disabilities caused by the *** cellular/molecular changes in MS are dynamic,with inflammation,demyelination and remyelination inducing progressive neurodegenerative changes in the central nervous system,as a ***,the imaging methods for accompanying the process are,as yet,shortcoming.

关键词： inflammation sclerosis myelin

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Proximity to corridors benefits bird communities in vegetated interrow vineyards in Mendoza, Argentina

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Avian Research 2024年第2期15卷 147-155页

作者： Andrea paula Goijman Agustín Zarco EEA La Consulta Instituto Nacional de Tecnología Agropecuaria(INTA)San CarlosMendozaArgentina Instituto Argentino de Investigacion en las Zonas Aridas(IADIZA)CONICET 5500MendozaArgentina

Management under ecological schemes and increasing habitat heterogeneity,are essential for enhancing biodiversity in *** provide several contributions to agriculture,for example pest control,recreation and enhancing human mental health,and have intrinsic *** are also ideal model organisms because they are easy to survey,and species respond differently to agricultural land use at different *** borders of crops are key for many species of birds,and distance to the border have been found to be an important factor in vineyard-dominated *** evaluate if there are differences in the bird assemblage,between the interior compared to borders within vineyards,using a hierarchical community occupancy *** hypoth-esized that occupancy of birds is greater in environments with greater heterogeneity,which in this study was considered to be contributed by the proximity to vegetated *** expected that vineyard borders close to corridors will have higher bird occupancy than the center of the *** research was conducted in three vineyards with biodiversity-friendly management practices,in Gualtallary,Mendoza,*** surveys were conducted over three breeding seasons from 2018 to *** and richness of the bird community was more closely associated with the borders adjacent to the corridors than with the interior of the vineyards,as we initially predicted,although the assemblage of birds did not differ *** than 75%of the registered species consume exclusively or partially ***-friendly management and ecological schemes,together with vegetated corridors provide multiple benefits for biodiversity *** ap-proaches not only minimize the use of agrochemicals but also prioritize soil cover with spontaneous vegetation,which supports a diverse community of insectivorous bird species,potentially contributing to pest control.

关键词： Avian Bayesian analysis Field scale agroecosystem Management Multi-species occupancy model Nature’s contributions to people

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