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Effect of Cardiac Rehabilitation on Physical Capacity of Heart Failure Patients in Senegal

World Journal of Cardiovascular Diseases 2024年第8期14卷 447-458页

作者： Ngoné Diaba Gaye Aliou Alassane Ngaidé Joseph Mingou Fatou Aw Mame Madjiguène Ka Aimé Mbaye Sy Zakaria Naji Lamrani Abdoul Kane Department of Cardiac Rehabilitation Ibra Mamadou Wane Medical Center Dakar Senegal Department of Cardiology Dalal Jam Hospital Guediawaye Senegal Department of Cardiology Idrissa Pouye General Hospital Dakar Senegal School of Medicine Cheikh Anta Diop University Dakar Senegal Department of Cardiology Principal Hospital of Dakar (HPD) Dakar Senegal.

Background: Heart failure is a chronic and severe condition that often results from various heart diseases. Cardiac rehabilitation (CR) is currently a crucial component in managing this condition. The aim was to assess the effects of cardiac rehabilitation on physical capacity of heart failure patients. Methods: This was a cross-sectional study conducted from February 1, 2021, to June 30, 2023. We included all patients with heart failure who underwent cardiac rehabilitation. Data analysis was performed using SPSS software version 24.0, with a significance level set at p Results: The study included 87 heart failure patients, with a male-to-female ratio of 1.8. Mean age was 57.10 years (±11.75). Coronary artery disease was the primary cause of heart failure, accounting for 75.9% of cases. Atrial fibrillation was present in 4.7% of cases. Following cardiac rehabilitation, Left Ventricular Ejection Fraction increased from 40.15% to 49.48% (p = 0.001). Resting heart rate decreased significantly from 81.4 bpm to 68.3 bpm (p = 0.000), and the number of METS increased from 4.3 to 6.57 (+56.8%;p = 0.000). The mean distance covered in the 6-minute walk test significantly increased from 337.8 meters to 522.7 meters (p = 0.000), reflecting a gain of 183.5 meters. Moreover, the increase in the number of METS was more pronounced in females (p = 0.001), non-obese individuals (p = 0.000), non-diabetics (p = 0.001), non-sedentary individuals (p = 0.000), and non-smokers (p = 0.000). The study reported a low readmissions rate of 2.2% and a mortality rate of 1.1%. Conclusion: Our study demonstrates that cardiac rehabilitation is beneficial for black African heart failure patients, resulting in significant improvements in symptoms, physical and capacity.

关键词： Cardiac Rehabilitation Chronic Heart Failure Physical Capacity Senegal

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Subsequent total joint arthroplasty: Are we learning from the first stage?

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World Journal of Orthopedics 2024年第3期15卷 230-237页

作者： Christine Jiang Wu Colin Penrose Sean Patrick Ryan Michael paul Bolognesi Thorsten Markus Seyler Samuel Secord Wellman Department of Orthopaedic Surgery Duke University HospitalDurhamNC 27710United States Department of Orthopaedic Surgery Midwest Center for Joint ReplacementIndianapolisIN 46241United States

BACKGROUND With the increasing incidence of total joint arthroplasty(TJA),there is a desire to reduce peri-operative complications and resource *** degenerative conditions progress in multiple joints,many patients undergo multiple *** To determine if both physicians and patients learn from the patient’s initial arth-roplasty,resulting in improved outcomes following the second *** The institutional database was retrospectively queried for primary total hip arth-roplasty(THA)and total knee arthroplasty(TKA).Patients with only unilateral THA or TKA,and patients undergoing same-day bilateral TJA,were *** demographics,comorbidities,and implant sizes were collected at the time of each procedure and patients were stratified by first vs second *** metrics evaluated included operative time,length of stay(LOS),disposition,90-d readmissions and emergency department(ED)*** A total of 642 patients,including 364 undergoing staged bilateral TKA and 278 undergoing bilateral THA,were *** was no significant difference in demographics or comorbidities between the first and second procedure,which were separated by a mean of 285 *** THA and TKA,LOS was significantly less for the second surgery,with 66%of patients having a shorter hospitalization(P<0.001).THA patients had significantly decreased operative time only when the same sized implant was utilized(P=0.025).The vast majority(93.3%)of patients were discharged to the same type of location following their second ***,when a change in disposition was present from the first surgery,patients were significantly more likely to be discharged to home after the second procedure(P=0.033).There was no difference between procedures for post-operative readmissions(P=0.438)or ED visits(P=0.915).CONCLUSION After gaining valuable experience recovering from the initial surgery,a patient’s perioperative outcomes are improved for their second *** may

关键词： Staged total joint arthroplasty Asynchronous total joint arthroplasty Subsequent total joint arthroplasty Contralateral total joint arthroplasty Perioperative outcomes

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Predictive Study of Trace Metal Pollution of Gold Panning Sites in Birimian Formations: Case of the Yaouré Furrow (Côte d’Ivoire)

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Open Journal of Applied Sciences 2024年第7期14卷 1691-1714页

作者： Tonga paul Tiemoko Gbele Ouattara Kouassi Ernest Ahoussi Laboratoire des Sciences Gographiques du Gnie Civil et des Gosciences Institut National Polytechnique Flix Houphout-Boigny (INP-HB) Yamoussoukro Cte dIvoire Laboratoiredes Sciences du Sol delEauetdes Gomatriaux Universit Flix Houphout-Boigny (UFHB) Abidjan-Cocody Cte dIvoire

The present study was carried out on small-scale gold mining sites in the Yaouré region of Côte d’Ivoire. This region is geologically representative of the Birimian formations (2.1 Ga) of West Africa. The aim is to determine the potentially toxic trace metals (TMEs) generated by these sites, with a view to preventing possible contamination and/or metal pollution of the waters that provide fish products for local populations. To this end, a sampling campaign was carried out, resulting in the collection of 20 mining waste samples analyzed by X-ray fluorescence spectrometry (XRF) and 10 by X-ray diffractometer (XRD). The XRF analysis detected 06 predominant TMEs: arsenic, chromium, copper, nickel, zinc and vanadium. Statistical analysis was carried out to determine the distributions and correlations between these ETMs. To assess contamination and/or pollution levels, the following indices were calculated on the basis of reference concentrations of upper continental crust MTEs: Enrichment Factor, Geo-accumulation Index, Concentration Factor, Degree of contamination and those related to ecological risks. The results of statistical analyses and indices have shown that arsenic and chromium are the most predominant and can be, depending on the chemical form, potentially more toxic. The results of the DRX analysis show the occurrence of several minerals carrying these two MTEs, especially that of a rare mineral, Stenhuggarite, an arsenic oxide linked to hydrothermal veins. The majority of gold mining operations in West Africa are located in the birimian zone, hence the need for environmental monitoring by the relevant authorities, to prevent potential ecological risks to water and possibly health risks via the food chain.

关键词： Small-Scale Mining Metallic Trace Elements Mining Discharges Contamination Pollution Contamination Pollution Index

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Impacts of Human Activities and Season on Species Diversity and Abundance of Butterflies in Mpanga Kipengere Game Reserve and Surrounding Farmlands, Tanzania

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Open Journal of Ecology 2024年第4期14卷 274-291页

作者： Privatus M. Kasisi Nsajigwa Mbije paul Lyimo Departiment of Ecosystem Science and Management College of Forest Wildlife and Tourism Sokoine University of Agriculture Morogoro Tanzania Departiment of Wildlife Management College of Forest Wildlife and Tourism Sokoine University of Agriculture Morogoro Tanzania

Maintaining natural habitats is crucial for the preservation of insects and other species that indicate environmental changes. However, the Mpanga/Kipengere Game Reserve and its surrounding farmlands are facing disturbance due to human activities, which is putting many wildlife species, particularly larger mammals, at risk. To determine the impact of human activities on butterfly species diversity and abundance in the reserve and its surrounding areas, we conducted a study from November 2021 to October 2023. We collected butterfly data using transect walks and baited traps in two habitat types. Our study yielded 2799 butterfly Individuals ranging in 124 species divided into five families habitat, season, and anthropogenic factors are significant environmental variables influencing species diversity and abundance of butterflies. Therefore, it’s important to protect habitat and dry-season water for the conservation of invertebrates such as butterflies. Our study findings provide essential information for ecological monitoring and future assessment of the Mpanga/Kipengere Game Reserve ecosystem health.

关键词： Mpanga Kipengere Game Reserve Species Diversity Habitat Butterflies Season Human Activities

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Potential of Applying Artificial Intelligence to Hot Metal Logistics Management

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China's Refractories 2024年第3期33卷 37-41页

作者： Maria Gabriela Garcia CAMPOS paul van BEURDEN Tata Steel IJmuiden 1970 CAThe Netherlands

The steel industry,known for its complexity and the need to reduce CO_(2)emissions,is adopting advanced digitalization tools to move towards a more sustainable,integrated,and agile operating *** twins with artificial intelligence-based optimization and scheduling models can improve decision-making in logistics,refractory maintenance,and energy *** incorporating advanced AI algorithms into this decision support system,the hot metal route scenarios can be evaluated,resulting in minimized hot metal temperature losses and increased scrap *** paper integrated digital twins with reinforcement learning algorithms to investigate the logistics of torpedoes and hot metal *** considered important input parameters such as the ladles and torpedoes'thermal state and location,refractory thickness,hot metal volume and temperature,and crane *** incorporating advanced AI algorithms into this decision support system,energy-efficient scenarios can be evaluated,increasing scrap utilization and resulting in a possible reduction of 15°C in hot metal temperature losses.

关键词： hot metal logistics energy efficiency artificial intelligence

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上海戏剧学院2020级音乐剧表演专业/舞美系毕业公演百老汇音乐剧《致埃文·汉森》剧照

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戏剧艺术 2024年第2期 I0005-I0006页

作者： Benj Pasek Justin paul Steven Levenson 不详

剧情梗概该剧讲述的是埃文·汉森,一位高中生,因为家庭的变故,常感到孤独,并患上了社交焦虑症。遵照心理医师的要求,他每天都要写一封致自己的信,以此来激励自己。可是他的一封信却被同班同学康纳·墨菲发现,让康纳误以为此信是埃文写... 详细信息

剧情梗概该剧讲述的是埃文·汉森,一位高中生,因为家庭的变故,常感到孤独,并患上了社交焦虑症。遵照心理医师的要求,他每天都要写一封致自己的信,以此来激励自己。可是他的一封信却被同班同学康纳·墨菲发现,让康纳误以为此信是埃文写给他的。不久传来康纳自杀身亡的消息,令所有人极度悲伤……此时康纳的父母也发现了埃文写的那封信,他们误以为自己的儿子和埃文是最亲密的好友,试图通过埃文去查清儿子的死因,为了安慰康納的家人,埃文决定将错就错。

关键词：上海戏剧学院自杀身亡心理医师同班同学康纳汉森一封信将错就错

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A simple and efficient CRISPR/Cas9 system permits ultra-multiplex genome editing in plants

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The Crop Journal 2024年第2期12卷 569-582页

作者： Suting Wu Htin Kyaw Zhijun Tong Yirong Yang Zhiwei Wang Liying Zhang Lihua Deng Zhiguo Zhang Bingguang Xiao William paul Quick Tiegang Lu Guoying Xiao Guannan Qin Xue'an Cui Biotechnology Research Institute Chinese Academy of Agricultural SciencesBeijing 100081China Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of EducationCollege of AgricultureFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Biological Breeding for Fujian and Taiwan Crops Ministry of Agriculture and Rural AffairsCollege of AgricultureFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125HunanChina School of Biosciences The University of SheffieldFirth CourtWestern BankSheffield S102TNUK Key Laboratory of Tobacco Biotechnological Breeding National Tobacco Genetic Engineering Research CenterYunnan Academy of Tobacco Agricultural SciencesKunming 650021YunnanChina

The development and maturation of the CRISPR/Cas genome editing system provides a valuable tool for plant functional genomics and genetic *** available genome-editing tools have a limited number of targets,restricting their application in genetic *** this study,we developed a novel CRISPR/Cas9 plant ultra-multiplex genome editing system consisting of two template vectors,eight donor vectors,four destination vectors,and one primer-design software *** combining the advantages of Golden Gate cloning to assemble multiple repetitive fragments and Gateway recombination to assemble large fragments and by changing the structure of the amplicons used to assemble sg RNA expression cassettes,the plant ultra-multiplex genome editing system can assemble a single binary vector targeting more than 40 genomic loci.A rice knockout vector containing 49 sg RNA expression cassettes was assembled and a high co-editing efficiency was *** plant ultra-multiplex genome editing system advances synthetic biology and plant genetic engineering.

关键词： CRISPR/Cas9 Multiplex genome editing Assembly system Plant

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Assessment of Selenium Contamination in Sediments of the Aby and Tendo Lagoons in Côte d’Ivoire

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International Journal of Geosciences 2024年第4期15卷 334-349页

作者： Stéphane Jean Claon Kouakou Serge Kouassi Kossonou Roland N’Guettia M’bassidjé Arsène Seka Guei Jokebed Dakouo Allico Joseph Djaman Kouakou Luc Kouadio Analytical Sciences and Public Health Department University of F&#233lix Houphou&#235t-Boigny Abidjan C&#244te d&#8217Ivoire Water Quality Control and Analysis Laboratory (LACQUE) Office National de l&#8217Eau Potable (ONEP) Abidjan C&#244te d&#8217Ivoire Biology and Health Laboratory University of F&#233lix Houphou&#235t-Boigny Abidjan C&#244te d&#8217Ivoire Laboratory of Environmental Sciences (LSE) University of Nangui Abrogoua Abidjan C&#244te d&#8217Ivoire Department of Medical and Fundamental Biochemistry Institut Pasteur of C&#244te d&#8217Ivoire Abidjan C&#244te d&#8217Ivoire

Selenium is a trace element that can have both beneficial and harmful effects on aquatic life. The Aby Lagoon is a coastal environment in Côte d’Ivoire that receives selenium inputs from various natural and anthropogenic sources. The aim of this study was to assess the levels of selenium in the sediments of the Aby Lagoon and its tributaries, the Tanoe River and the Tendo Lagoon, and to examine the spatial and seasonal variations of selenium concentrations. Sediment samples were collected from different sites and seasons, and selenium concentrations were measured by atomic fluorescence spectrometry. The results showed that the average concentration of selenium in the sediments of the Aby Lagoon was 0.82 mg/kg, indicating moderate contamination. The concentration of selenium varied between sites and seasons, with higher values in the channel of the Tendo Lagoon and during the dry season. The study highlighted the complexity of selenium dynamics in aquatic ecosystems, and the need to take into account seasonal and spatial variability as well as interactions between environmental factors. The study also suggested potential ecotoxicological risks for some sensitive organisms in certain areas of the lagoon. This study contributes to the knowledge of the dynamics of selenium in lagoon ecosystems and to the assessment of the environmental risks associated with its presence.

关键词： Tropical Estuarine Selenium Sediments Aby Lagoon Seasonal Distribution

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Norian(Late Triassic) conodonts from the Raohe area， Heilongjiang， Northeastern China

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Journal of Earth Science 2024年

作者： Xianlang Wu paul B.Wignall Xulong Lai Yan Chen Jinling Yuan Guiyue Luo Haishui Jiang State Key Laboratory of Biogeology and Environmental Geology， School of Earth Sciences， China University of Geosciences School of Earth and Environment， University of Leeds Hubei Institute of Geosciences

The Raohe area of Heilongjiang Province， Northeast China belongs to the Nadanhada Terrane， which was in low latitudes of Panthalassa during the Triassic. The composition of the Late Triassic conodont fauna， derived from limestone lenses interpreted to be formed on seamounts， provides important new information on the pelagic biota in this ocean. new conodont samples collected from sections at Minzhu， Minnan and Chigangbei belong to three Norian conodont zones. In ascending order， they are: Mockina postera Zone， Mockina bidentata Zone and Parvigondolella andrusovi Zone. The Norian conodont fauna in the Raohe area has distinct attributes: there are a lot of cosmopolitan species (e.g. Mockina postera， Mockina bidentata， Parvigondolella andrusovi) which enable good global correlation; endemic conodont species are also present， (e.g. Mockina sakurae， Mockina shamiseni， Norigondolella nadanhadaensis) indicating that Panthalassa Ocean conodont populations also contains unique taxa; and some conodonts belong to taxa with much shorter ranges in surrounding epeiric seas (e.g. Carnepigondolella pseudoechinata， neocavitella cavitata and Epigondolella vialovi). The presence of the latter “relicts” indicates that the seamounts were persistently suitable habitats for many millions of years in the Late Triassic.

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Spatio-Temporal Change of Dispersal Areas of Greater Kudu (Tragelaphus strepsiceros) in Lake Bogoria Landscape, Kenya

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Open Journal of Ecology 2024年第3期14卷 183-198页

作者： Beatrice Chepkoech Cheserek George Morara Ogendi paul Mutua Makenzi Department of Environmental Science Egerton University Njoro Kenya

Decline in wildlife populations is manifest globally, regionally and locally. A wildlife decline of 68% has been reported in Kenya’s rangelands with Baringo County experiencing more than 85% wildlife loss in the last four decades. Greater Kudu (Tragelaphus strepsiceros) is endemic to Lake Bogoria landscape in Baringo County and constitutes a major tourist attraction for the region necessitating use of its photo on the County’s logo and thus a flagship species. Tourism plays a central role in Baringo County’s economy and is a major source of potential growth and employment creation. The study was carried out to assess spatio-temporal change of dispersal areas of Greater Kudu (GK) in Lake Bogoria landscape in the last four years for enhanced adaptive management and improved livelihoods. GK population distribution primary data collected in December 2022 and secondary data acquired from Lake Bogoria National Game Reserve (LBNGR) for 2019 and 2020 were digitized using in a Geographic Information System (GIS). Measures of dispersion and point pattern analysis (PPA) were used to analyze dispersal of GK population using GIS. Spatio-temporal change of GK dispersal in LBNR was evident thus the null hypothesis was rejected. It is recommended that anthropogenic activities contributing to GK’s habitat degradation be curbed by providing alternative livelihood sources and promoting community adoption of sustainable technologies for improved livelihoods.

关键词： Spatio-Temporal Change Dispersal Greater Kudu (Tragelaphus Strepsiceros) Point Pattern Analysis (PPA) GIS

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