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Accuracy of biometric formulae for intraocular lens power calculation in a teaching hospital

International Journal of Ophthalmology(English edition) 2020年第1期13卷 61-65页

作者： Kevin S Tang Elaine M Tran Allison J chen David R Rivera Jorge J Rivera paul B Greenberg Division of Ophthalmology Alpert Medical SchoolBrown UniversityProvidence 02903Rhode IslandUSA Section of Ophthalmology Providence VA Medical CenterProvidence 02908Rhode IslandUSA Shiley Eye Institute and Department of Ophthalmology University of California San DiegoLa Jolla 92093CaliforniaUSA

AIM: To evaluate the accuracy of three commonly used biometric formulae across different axial lengths(ALs) at one United States Veterans Affairs teaching ***: A retrospective chart review was conducted from November 2013 to May 2018. One eye of each patient who underwent cataract surgery with a monofocal intraocular lens(IOL) was included. The range of postoperative follow-up period was from 3 wk to 4 mo. The Holladay 2, Barrett Universal II, and Hill-Radial Basis Function(Hill-RBF) formulae were used to predict the postoperative refraction for all cataract surgeries. For each formula, we calculated the prediction errors [including mean absolute prediction error(MAE)] and the percentage of eyes within ±0.25 diopter(D) and ±0.5 D of predicted refraction. We performed subgroup analyses for short(AL25.0 mm).RESULTS: A total of 1131 patients were screened, and 909 met the inclusion criteria. Resident ophthalmologists were the primary surgeons in 710(78.1%) cases. We found no statistically significant difference in predictive accuracy among the three formulae over the entire AL range or in the short, medium, and long eye subgroups. Across the entire AL range, the Hill-RBF formula resulted in the lowest MAE(0.384 D) and the highest percentage of eyes with postoperative refraction within ±0.25 D(42.7%) and ±0.5 D(75.5%) of predicted. All three formulae had the highest MAEs(>0.5 D) and lowest percentage within ±0.5 D of predicted refraction(<55%) in short ***: In cataract surgery patients at our teaching hospital, three commonly used biometric formulae demonstrate similar refractive accuracy across all ALs. Short eyes pose the greatest challenge to predicting postoperative refractive error.

关键词： cataract surgery biometry intraocular lens power calculation

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Robust Tracking Control for Self-balancing Mobile Robots Using Disturbance Observer

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IEEE/CAA Journal of Automatica Sinica 2017年第3期4卷 458-465页

作者： Mou chen College of Automation Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China IEEE

In this paper,a robust tracking control scheme based on nonlinear disturbance observer is developed for the self-balancing mobile robot with external unknown disturbances.A desired velocity control law is firstly designed using the Lyapunov analysis method and the arctan *** improve the tracking control performance,a nonlinear disturbance observer is developed to estimate the unknown disturbance of the self-balancing mobile *** the output of the designed disturbance observer,the robust tracking control scheme is presented employing the sliding mode method for the selfbalancing mobile *** simulation results further demonstrate the effectiveness of the proposed robust tracking control scheme for the self-balancing mobile robot subject to external unknown disturbances.

关键词： Disturbance observer robust tracking control self-balancing mobile robot sliding mode control(SMC)

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Construction of an Unusual Two-Dimensional Layered Structure for Fused-Ring Energetic Materials with High Energy and Good Stability

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Engineering 2020年第9期6卷 1136-1143页

作者： Yongan Feng Mucong Deng Siwei Song Sitong chen Qinghua Zhang Jean’ne M.Shreeve Department of Chemistry University of IdahoMoscowID 83844-2343USA Institute of Chemical Materials China Academy of Engineering PhysicsMianyang 621900China

制造具有良好机械感度的高性能含能材料在过去几十年里一直是一项重大挑战,因为这类蕴含巨大能量的材料存在内在的不稳定性。本文研究了一种极具潜力的稠环含能材料:4-硝基-7-叠氮基-吡唑-[3,4-d]-1,2,3-三嗪-2-氧(NAPTO)。这种物质具... 详细信息

制造具有良好机械感度的高性能含能材料在过去几十年里一直是一项重大挑战,因为这类蕴含巨大能量的材料存在内在的不稳定性。本文研究了一种极具潜力的稠环含能材料:4-硝基-7-叠氮基-吡唑-[3,4-d]-1,2,3-三嗪-2-氧(NAPTO)。这种物质具有不同寻常的二维(2D)层状结构,其绝对结构已经单晶X射线衍射证实。研究显示,这一结构新颖的含能物质具有惊人的能量[如爆速(D)高达9.12 km·s^-1,爆压(P)为35.1 GPa]、优异的机械感度[撞击感度(IS)为18 J、摩擦感度(FS)为325 N、静电感度(EDS)为0.32 J]和良好的热分解温度(203.2℃),展示出高能量与低感度的双重优势。据我们所知,NAPTO是首个具有二维层状结构的稠环含能材料。与此同时,运用分子模拟分析了其在外界机械刺激下的稳定机制,结果表明,该含能材料超平的二维层状结构比其他结构更能有效地缓冲外界机械刺激,从而将作用在材料上的机械能转化为晶体的层间滑动与压缩。本研究从实验和理论两个方面揭示了稠环二维层状结构在制造先进含能材料方面的巨大潜力。

关键词：含能材料稠环杂环化合物二维层状结构高能量稳定性感度

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A proteome-wide screen identifies valosin-containing protein as an essential regulator of podocyte endoplasmic reticulum stress

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Chinese Science Bulletin 2012年第20期57卷 2493-2505页

作者： HUANG ZhiYong HONG Quan XUE Peng paul Goulding FENG Zhe WANG LiYuan MEI Yan WU LingLing chen XiangMei WU Di State Key Laboratory of Kidney Disease(2011DAV00088) Kidney Department&Institute of NephrologyDivision of Clinical Internal MedicineChinese People’s Liberation Army General HospitalBeijing 100853China Laboratory of Proteomics Institute of BiophysicsChinese Academy of SciencesBeijing 100101China Nonlinear Dynamics Ltd Keel HouseGarth HeadsNewcastle upon TyneNE12JEUK

To investigate proteins expressed in the renal tissue of the passive Heymann nephritis (pHN) rat model,we prepared pHN rat models with anti-FxA1 serum and analyzed the proteins differentially expressed in the kidney tissue with label-free liquid chromatography-tandem mass *** then analyzed in depth the endoplasmic reticulum stress (ERS)-related protein using an online bioinformatics ***-one differential proteins and their annotations were *** Ontology (GO) function analysis showed that 16 proteins were involved in cellular metabolism and 22 were proteins related to catalytic activity,including protein folding or ***-GO networks indicated that VCP could interact with the ERS marker HSPa5,with both involved in a single *** inhibition of podocyte VCP by RNAi under normal conditions,the HSPa5 expression level did not change,but when the cell was subjected to ERS by tunicamycin,HSPa5 expression significantly increased with RNAi of VCP when compared with the tunicamycin-treated *** results showed that ERS plays an important role in podocyte injury of membranous nephropathy and is mediated by an HSPa5-VCP signaling pathway,in which the most predominant proteins are those related to cellular metabolism and catalytic activity.

关键词：蛋白质折叠内质网应激细胞损伤 networks公司宽屏幕标识大鼠模型催化活性

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Initial movement of the Karakorum Fault in western Tibet:constraints from SHRIMP U-Pb dating of zircons

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Chinese Science Bulletin 2007年第8期52卷 1089-1100页

作者： LI HaiBing Franck VALLI LIU DunYi XU ZhiQin YANG JingSui Nicolas ARNAUD paul TAPPONNIER Robin LACASSIN chen SongYong QI xuexiang Laboratory of Continental Dynamics Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 China Department of Earth Science Hongkong University Hongkong China Institut de Physique du Globe de Paris 75252 Paris CX05 France Beijing SHRIMP Center Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 China ISTEEM-USTL Place Eugene Bataillon 34095 Montpellier CX5 France

The Karakorum Fault zone(KFZ)plays an important role in understanding the formation,evolvement and deformation of the Tibetan *** high-T dextral shearing metamorphic rocks,e.g.,mylonites or mylonitized gneisses-granites,locally crop out along the southeastern part of the KFZ in the Ayila Ri’gyüRange *** SHRIMP U-Pb dating of the syn-kinematic crystallized zircons indicates that the initial age of the KFZ is^27 Ma,~10 Ma older than previous *** extensive high-T dextral shearing along the KFZ started at least at 27-20 Ma,accompanied by the syn-kinematic emplacement of *** and concomitant fluid circulation during shearing most likely occurred as early as at 25-13 *** KFZ probably grew from southeast to northwest along the fault as a result of continuous convergence between the India plate and Eurasia plate.

关键词：西藏西部喀拉昆仑断裂带锆石 SHRIMP U-Pb 测年

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Catalytic microwave assisted pyrolysis of aspen

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International Journal of Agricultural and Biological Engineering 2009年第4期2卷 70-75页

作者： Johannes Moen Changyan Yang Bo Zhang Hanwu Lei Kevin Hennessy Yiqin Wan Zhiping Le Yuhuan Liu paul chen Roger Ruan Center for Biorefining Department of Biosystems and Agricultural EngineeringUniversity of Minnesota1390 Eckles Ave.St.PaulMN 55108USA Department of Mathematical Sciences and Technology Norwegian University of Life SciencesPostboks 50031432ÅsNorway School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyHubei 430074China Center for Bioproducts and Bioenergy Department of Biological Systems EngineeringWashington State UniversityRichlandWA 99354 USA Jiangxi Biomass Engineering Center Nanchang UniversityNanchang 330047China

The effect of catalysts on the microwave pyrolysis of aspen pellets was studied.A range of chlorides,nitrates and metal-oxides were added at 2%of the aspen mass(air dry aspen pellet weight basis).Chlorides in particular were found to favor liquid yield,especially the yield of water phase *** liquid yield with added chlorides was 41%mass of the total biomass input,compared to 35%mass without ***-oxides were found to favor pyrolysis heavy oil,and thus total oil yield,since the yield of light oils seemed to be fairly *** were found to favor pyrolysis gas *** light oils and light oils blended with diesel were found to be a potential diesel fuel substitute.

关键词： Renewable energy pyrolysis microwave pyrolysis pyrolysis liquids bio-oils pyrolysis catalysts

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A short-chain α-neurotoxin from Naja naja atra produces potent cholinergic-dependent analgesia

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neuroscience Bulletin 2006年第2期22卷 103-109页

作者： Hui-Ling ZHANG Rong HAN Zhen-Lun GU Zhi-Xing chen Bo-Wen chen paul F. Reid Laurence N. Raymond Zheng-Hong QIN Department of Pharmacology Soochow University School of Medicine Suzhou 215007 China ReceptoPharm Plantation Florida USA

Objective To investigate the analgesia induced by cobrotoxin （CT） from venom of Naja naja atra, and the effects of atropine and naloxone on the antinociceptive activity of CT in rodent pain models. Methods CT was administered intraperitoneally （33.3, 50, 75 μg/kg）, intra-cerebral venticularly （2.4 μg/kg） or microinjected into periaqueductal gray （PAG, 1.2 μg/kg）. The antinociceptive action was tested using the hot-plate test and the acetic acid writhing test in mice and rats. The involvement of cholinergic system and the opioid system in CT-induced analgesia was examined by pretreatment of animals with atropine （0.5 mg/kg, im or 10 mg/kg, ip） or naloxone （3 mg/kg, ip）. The effect of CT on motor activity was tested using the Animex test. Results CT （33.3, 50 and 75 μg/kg, ip） exhibited a dosedependent analgesic action in mice as determined with hot-plate test and acetic acid writhing test. In the mouse acetic acid writhing test, the intra-cerebral ventricle administration of CT 2.4 μg/kg （1/23th of a systemic dose） produced marked analgesic effects. Microinjection of CT 1.2 μg/kg （1/46th of systemic dose） into the PAG also elicited a robust analgesic action in the hot-plate test in rats. Atropine at 0.5 mg/kg （ira） or naloxone at 3 mg/kg （ip） failed to block the analgesic effects of CT, but atropine at 10 mg/kg （ip） did antagonize the analgesia mediated by CT in the mouse acetic acid writhing test. At the highest effective dose of antinociception （75 μg/kg）, CT did not change the spontaneous mobility of mice. Conclusion These results suggest that CT from Naja naja atra venom has analgesic effects. Central nervous system may be involved in CT＇ analgesic effects and the PAG may be the primary central site where CT exerts its effects. The central cholinergic system but not opioid system appears to be involved in the antinociceptive action of CT.

关键词： cobrotoxin analgesia periaqueductal gray matter atropine naloxone

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Identification of Concealed Faults in a Grassland Area in Inner Mongolia, China, Using the Temperature Vegetation Dryness Index

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Journal of Earth Science 2019年第4期30卷 853-860页

作者： chengbin Wang Jianguo chen Xi chen Jinhui chen State Key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesWuhan 430074China Faculty of Earth Resources、China University of Geosciences Wuhan 430074China Hubei Geological Survey Wuhan 430034China

Fault identification in vegetated area(e.g.,grassland) is a major challenge compared to that in outcrop areas. To identify concealed faults in a grassland covered area,a hybrid method combining the temperature vegetation dryness index(TVDI) and the singularity index was proposed in this paper to extract TVDI anomalies associated with concealed fractures in the Sonid Left Banner Grassland,Inner Mongolia,North China. In the triangle space of LST/NDVI(land surface temperature/normalized difference vegetation index),scattered points were concentrated in the areas of partial and full cover,while few data points were in the areas of bare soil with low values of NDVI and high values of LST;this result is consistent with the semiarid grassland landscape of the study area. Although TVDI imaging shows an obvious linear pattern with an ne-Nne trend,which indicates the existence of concealed faults,the surrounding background weakened and reduced the significance of the *** better delineate the concealed faults,the singularity index was employed to remove the influence of the background and enhance the TVDI anomalies associated with the concealed faults. The TVDI imaging and singularity index mapping showed Nne and ne orientations;this finding is consistent with the regional tectonic framework. Geological mapping footprints showed that the hybrid method is useful to identify concealed faults in covered areas of grassland.

关键词： concealed fracture TVDI grassland Inner Mongolia singularity index

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Exploiting oleic acid to prepare two-dimensional assembly of Si@graphitic carbon yolk-shell nanoparticles for lithium-ion battery anodes

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Nano Research 2019年第3期12卷 631-636页

作者： Xiao chen chen chen Yu Zhang Xianfeng Zhang Dong Yang Angang Dong State Key Laboratory of Molecular Engineering of Polymer and Department of Macromolecular Science Fudan University Shanghai 200433 China Chem Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and Department of Chemistry Fudan University Shanghai 200433 China

Carbon coati ng has bee n a routi ne strategy for improvi ng the performa nee of Si-based anode materials for lithium-ion batteries. The ability to tailor the thick ness, homoge neity and graph itizati on degree of carb on-coati ng layers is esse ntial for addressi ng issues that hamper the real applicatio ns of Si anodes. Herein, we report the con structio n of two-dime nsional (2D) assemblies of intercon nected Si @ graphitic carb on yolk-shell nano particles (2D-Si@gC) from commercial Si powders by exploiting oleic acid (OA). The OA molecules act as both the surface-coati ng liga nds for facilitating 2D nano particle assembly and the precursor for forming uniform and conformal graphitic shells as thin as 4 nm. The as-prepared 2D-Si@gC with rationally designed void space exhibits excellent rate capability and cycling stability when used as anode materials for lithium-ion batteries, delivering a capacity of 1,150 mAh·g^-1 at an ultrahigh current density of 10 A·g^-1 and maintaining a stabilized capacity of 1,275 mAh·g^-1 after 200 cycles at 4 A·g^-1 The formatio n of yolk-shell nano particles 8nfines the depositi on of solid electrolyte in terphase (SEI) onto the outer carb on shell, while simulta neously providing sufficie nt space for volumetric expa nsion of Si nano particles. These attributes effectively mitigate the thickness variations of the entire electrode during repeated lithiation and delithiation, which combined with the unique 2D architecture and interc onn ected graphitic carbon shells of 2D-Si@gC contributes to its superior rate capability and cycling performa nee.

关键词： oleic acid self-assembly graphitic carbon yolk-shell nanoparticles Sianodes

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A Systematic Approach for Making 3D-Printed Patient-Specific Implants for Craniomaxillofacial Reconstruction

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Engineering 2020年第11期6卷 1291-1301页

作者： Ruxu Du Yu-Xiong Su Yu Yan Wing Shan Choi Wei-Fa Yang Chunyu Zhang Xianshuai chen Justin paul Curtin Jianglin Ouyang Bitao Zhang Shien-Ming Wu School of Intelligent Engineering South China University of TechnologyGuangzhou 511442China Oral and Maxillofacial Surgery Faculty of DentistryThe University of Hong KongHong Kong 999077China Foshan Angels Biotechnology Co. Ltd.Foshan 528200China

Craniomaxillofacial reconstruction implants,which are extensively used in head and neck surgery,are conventionally made in standardized *** surgery,the implant must be bended manually to match the anatomy of the individual *** bending process is time-consuming,especially for inexperienced ***,repetitive bending may induce undesirable internal stress concentration,resulting in fatigue under masticatory loading in v iv o and causing various complications such as implant fracture,screw loosening,and bone *** have been reports on the use of patient-specific 3D-printed implants for craniomaxillofacial reconstruction,although few reports have considered implant *** this paper,we present a systematic approach for making 3D-printed patientspecific surgical implants for craniomaxillofacial *** approach consists of three parts:First,an easy-to-use design module is developed using Solidworks®software,which helps surgeons to design the implants and the axillary fixtures for *** engineers can then carry out the detailed design and use finite-element modeling(FEM)to optimize the ***,the fabrication process is carried out in three steps:0 testing the quality of the powder;(2)setting up the appropriate process parameters and running the 3D printing process;and (3)conducting post-processing treatments(i.e.,heat and surface treatments)to ensure the quality and performance of the ***,the operation begins after the final checking of the implant and *** the surgery,postoperative rehabilitation follow-up can be carried out using our patient tracking *** this systematic approach,we have successfully conducted a total of 41 surgical cases.3D-printed patient-specific implants have a number of advantages;in particular,their use reduces surgery time and shortens patient recovery ***,the presented approach helps to ensure implant quality.

关键词： Patient-specific implant Craniomaxillofacial reconstruction 3D printing Surgery

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