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Journal of Ocean Engineering and science 2024年第5期9卷 489-507页

作者： shailendra singh s.saha ray National Institute of Technology Department of MathematicsRourkela 769008India

In this paper,a new eighth-order(1+1)-dimensional time-dependent extended KdV equation has been *** considered equation is being found completely integrable by using the Painlevéanalysis ***,three auto-Bäcklund transformations have been generated by truncating the Painlevéseries at a constant *** auto-Bäcklund transformations have been used to derive various analytic solution families for the newly developed *** solutions include the kink-antikink soliton,kink-soliton,antikink-soliton,periodic-soliton,complex kink-soliton and complex periodic-soliton ***-soliton solutions including N-soliton solution,have been obtained by using the simplified Hirota’s method for the considered *** the results are being expressed graphically to signify the physical importance of the considered equation.

关键词： Higher-order KdV equation Painlevéanalysis Auto-Bäcklund transformation simplified Hirota method

Numerical simulation of square shaped particle sedimentation

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Particuology 2024年第1期84卷 107-116页

作者： Govind sharma Bahni ray Department of Mechanical Engineering Indian Institute of Technology DelhiHauz KhasNew Delhi110016India

Direct numerical simulations of square particle sedimentation in a viscous incompressible fluid are presented to examine the effects of sharp edges for various particle-to-fluid density ratios and different initial inclination *** settling process exhibits four different motion regimes;non-oscillatory,non-uniform centered oscillatory,uniform off-centered oscillatory,and non-uniform off-centered(irregular)*** moderate density ratios,we observe that the rotational motion of settling square particle varies with the initial inclination *** employ Dynamic Time Warping and Fast Fourier Transform to analyze translational and angular *** systems are described using phase-space plots,and a chaotic phenomenon is observed at a higher density ratio.

关键词： sedimentation Distributed Lagrangian multiplier Phase synchronization Oscillations

Novel wild edible mushroom Astraeus hygrometricus(Pers.)Morgan induces robust apoptosis on human acute lymphoblastic leukemia cells through a RONs-subsisted mitochondria-dependent pathway

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Journal of Traditional Chinese Medical sciences 2024年第1期11卷 67-77页

作者： Amrita Pal Ribhu ray Anirban Chouni subhadip Hajra santanu paul Department of Botany University of CalcuttaKolkata 700019India Department of Cancer Chemoprevention Chittaranjan National Cancer InstituteKolkata 700026India

Objective:To explore the therapeutic effects of the novel wild edible mushroom Astraeus hygrometricus(Pers.)Morgan(***)on human acute lymphoblastic leukemia ***:Extensive screening of the antiproliferative and chemopreventive potential of different extracts from 5 wild mushrooms,***,Phallus sp.,Lentinus sp.,Tricholoma sp.,and serpula *** performed against a panel of 6 cancer cell lines and normal cells using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)*** determination,cell cycle profiling,intracellular reactive oxygen species(ROs)and reactive nitrogen species(RNs),and mitochondrial membrane potential were analyzed by flow *** activity of caspases was measured colorimetrically,and the expression pattern of mitochondrial proteins was ***:The methanol extract of *** and MOLT-4 cells were identified as the most potent extract exhibiting antiproliferative activity and most sensitive cell line,*** mushroom extract induced robust selective apoptosis in MOLT-4 cells and arrested cell cycle progression at the G0/G1 *** extract disrupted the mitochondrial membrane potential and enhanced ROs production in MOLT-4 *** methanol extract induced apoptosis by downregulating the expression of Bcl-2,increasing the expression of Bax,and activating the caspase ***:The novel wild edible mushroom is a potential repository of biomolecules for the development of antileukemic drugs.

关键词： Mushroom Astraeus hygrometricus(Pers.)Morgan Apoptosis Antileukemic

TALYs calculation and a short review of the experimental status of proton capture studies on p-nuclei:A guide to future investigation

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Chinese Physics C 2024年第6期48卷 102-111页

作者： Indrani ray Argha Deb Physics Department Jadavpur UniversityKolkata-700032India

TALYs calculations were performed to obtain the theoretical proton capture cross-sections on the p-nuclei.A short review on the status of related experimental studies was also *** basic properties such as Q-values,Coulomb barrier,Gamow peak,Gamow Window,and decay properties of the parent and daughter nuclei were *** experimental parameters,e.g.,beam energy,beam current,targets,and detectors,used in experimental investigations reported in the literature,were *** results of the TALYs calculations in the Gamow region were compared with the corresponding experimental values wherever *** study is expected to facilitate the planning of future experiments.

关键词： p-nuclei proton capture cross-section gamma ray Gamow energy TALYs TENDL KADoNis

Prediction of Bandwidth of Metamaterial Antenna Using Pearson Kernel-Based Techniques

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Computers, Materials & Continua 2024年第3期78卷 3449-3467页

作者： sherly Alphonse s.Abinaya sourabh paul school of Computer science and Engineering Vellore Institute of TechnologyChennai600127India school of Electronics Engineering Vellore Institute of TechnologyChennai600127India

The use of metamaterial enhances the performance of a specific class of antennas known as metamaterial *** radiation cost and quality factor of the antenna are influenced by the size of the *** antennas allow for the circumvention of the bandwidth restriction for small *** parameters have recently been predicted using machine learning algorithms in existing *** learning can take the place of the manual process of experimenting to find the ideal simulated antenna *** accuracy of the prediction will be primarily dependent on the model that is *** this paper,a novel method for forecasting the bandwidth of the metamaterial antenna is proposed,based on using the Pearson Kernel as a standard *** with these new approaches,this paper suggests a unique hypersphere-based normalization to normalize the values of the dataset attributes and a dimensionality reduction method based on the Pearson kernel to reduce the dimension.A novel algorithm for optimizing the parameters of Convolutional Neural Network(CNN)based on improved Bat Algorithm-based Optimization with Pearson Mutation(BAO-PM)is also presented in this *** prediction results of the proposed work are better when compared to the existing models in the literature.

关键词： Antenna pearson optimization bandwidth metamaterial

Functional cure of chronic hepatitis B-hope or hype?

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World Journal of Hepatology 2024年第9期16卷 1199-1205页

作者： Gautam ray Gastroenterology Unit Department of MedicineB.R.Singh HospitalKolkata 700014West BengalIndia

Chronic hepatitis B constitutes a substantial disease burden *** steps advocated by the World Health Organization in 2016 to eradicate hepatitis B by 2030 has failed to achieve significant progress,especially with respect to immu-nization coverage and linkage to *** lack of governmental and public awar-eness regarding the long-term implications of hepatitis B burden cause under-funding of developmental *** presently approved treatment modalities have limited efficacy in complete viral eradication,hence the need for newer molecules to achieve functional cure(sustained undetectable hepatitis B surface antigen(HBsAg)and hepatitis B virus DNA in peripheral blood after a finite period of therapy).However,preliminary results from trials of novel therapies show their inadequacy to achieve this end by themselves but better performance with a low baseline serum HBsAg with nucleos(t)ide analogues(NA)treatment which need to be combined with/without pegylated interferon as an *** therapy is limited by cost and adverse events and need to show incremental benefit over the standard of care(long-term NA therapy)with respect to efficacy and drug toxicities,making the development process ***,while such therapies continue to be tested,strategies should still focus on prevention of transmission by non-pharmaceutical measures,vaccination and increasing linkage to care.

关键词： Hepatitis B Drugs Clinical trial Therapy Novel therapies Functional cure

A new method for deriving broad-band polar motion geodetic excitations

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Geodesy and Geodynamics 2024年第5期15卷 453-464页

作者： Wei Chen Jiesi Luo Jim ray Jiancheng Li Hubei Luojia Laboratory School of Geodesy and GeomaticsWuhan UniversityWuhan 430079China National Oceanic and Atmospheric Administration Silver SpringMDUSA Central south University Changsha 410083China

While the geodetic excitationχ(t)of polar motion p(t)is essential to improve our understanding of global mass redistributions and relative motions with respect to the terrestrial frame,the widely adopted method to deriveχ(t)from p(t)has biases in both amplitude and phase *** study has developed a new simple but more accurate method based on the combination of the frequency-and time-domain Liouville's equation(FTLE).The FTLE method has been validated not only with 6-h sampled synthetic excitation series but also with daily and 6-h sampled polar motion measurements as well asχ(t)produced by the interactive webpage tool of the International Earth Rotation and Reference systems service(IERs).Numerical comparisons demonstrate thatχ(t)derived from the FTLE method has superior performances in both the time and frequency domains with respect to that obtained from the widely adopted method or the IERs webpage tool,provided that the input p(t)series has a length around or more than 25 years,which presents no practical limitations since the necessary polar motion data are readily *** FTLE code is provided in the form of Mat Lab function.

关键词： Earth rotation Polar motion Geodetic excitation Liouville's equation Mat Lab

Application of a simplified ADM1 for full-scale anaerobic co-digestion of cattle slurry and grass silage:assessment of input variability

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Frontiers of Environmental science & Engineering 2024年第4期18卷 125-139页

作者： sofia Tisocco sören Weinrich Gary Lyons Michael Wills Xinmin Zhan paul Crosson Civil Engineering College of Science and EngineeringUniversity of GalwayGalwayH91 TK33Ireland Teagasc Animal and Bioscience Research Department Animal and Grassland Research and Innovation CentreDunsanyC15 PW93Ireland Biochemical Conversion Department Deutsches Biomasseforschungszentrum gemeinnützige GmbHLeipzig 04347Germany Faculty of Energy·Building services·Environmental Engineering Münster University of Applied SciencesSteinfurt 48565Germany Agri-Food and Biosciences Institute HillsboroughBT266DRUK Ryan Institute University of GalwayGalwayH91 TK33Ireland MaREI Research Centre for Energy Climate and MarineRyan InstituteUniversity of GalwayGalwayH91 TK33Ireland

Mathematical modeling of anaerobic digestion is a powerful tool to predict gas yields and optimize the *** Anaerobic Digestion Model No.1(ADM1)is a widely implemented model for this ***,modeling full-scale biogas plants is challenging due to the extensive substrate and parameter characterization *** study describes the modification of the ADM1 through a simplification of individual process phases,characteristic components and required ***,the ability of the simplified model to simulate the co-digestion of grass silage and cattle slurry was evaluated using data from a full-scale biogas *** impacts of substrate composition(crude carbohydrate,protein and lipid concentration)and variability of carbohydrate degradability on simulation results were assessed to identify the most influential *** indicated that the simplified version was able to depict biogas and biomethane production with average model efficiencies,according to the Nash-sutcliffe efficiency(NsE)coefficient,of 0.70 and 0.67,respectively,and was comparable to the original ADM1(average model efficiencies of 0.71 and 0.63,respectively).The variability of crude carbohydrate,protein and lipid concentration did not significantly impact biogas and biomethane output for the data sets *** contrast,carbohydrate degradability seemed to explain much more of the variability in the biogas and methane ***,the application of simplified models provides a reliable basis for the process simulation and optimization of full-scale agricultural biogas plants.

关键词： ADM1 Agricultural feedstocks Biogas technology Input variability Parameter estimation

Population Dynamics in an Advective Environment

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Communications on Applied Mathematics and Computation 2024年第1期6卷 399-430页

作者： King-Yeung Lam ray Lee Yuan Lou Department of Mathematics The Ohio State UniversityColumbusOH43210USA school of Mathematical sciences CMA-Shanghai and MOE-LSCShanghai Jiao Tong UniversityShanghai200240China

We consider a one-dimensional reaction-diffusion equation describing single-and two-species population dynamics in an advective environment,based on the modeling frameworks proposed by Lutscher et *** *** analyze the effect of rate of loss of individuals at both the upstream and downstream *** the single-species case,we prove the existence of the critical domain size and provide explicit formulas in terms of model *** further derive qualitative properties of the critical domain size and show that,in some cases,the critical domain size is either strictly decreasing over all diffusion rates,or monotonically increasing after first decreasing to a *** also consider competition between species differing only in their diffusion *** two species having large diffusion rates,we give a sufficient condition to determine whether the faster or slower diffuser wins the *** also briefly discuss applications of these results to competition in species whose spatial niche is affected by shifting isotherms caused by climate change.

关键词： Reaction-diffusion-advection Critical domain size Competition Climate change

Hypoxic and temporal variation in the endocrine disrupting toxicity of perfluorobutanesulfonate in marine medaka(Oryzias melastigma)

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Journal of Environmental sciences 2024年第2期136卷 279-291页

作者： Baili sun Jing Li Yachen Bai Xiangzhen Zhou paul K.s.Lam Lianguo Chen state Key Laboratory of Freshwater Ecology and Biotechnology Institute of HydrobiologyChinese Academy of SciencesWuhan 430072China University of Chinese Academy of sciences Beijing 100049China Office of the President Hong Kong Metropolitan University30 Good Shepherd StreetKowloonHong Kong SARChina

Perfluorobutanesulfonate(PFBs)is an emerging pollutant capable of potently disrupting the sex and thyroid endocrine systems of ***,the hypoxic and temporal variation in PFBs endocrine disrupting toxicity remain largely *** the present study,adult marine medaka were exposed to environmentally realistic concentrations of PFBs(0 and 10μg/L)under normoxia or hypoxia conditions for 7 days,aiming to explore the interactive behavior between PFBs and *** addition,PFBs singular exposure was extended till 21days under normoxia to elucidate the time-course progression in PFBs *** results showed that hypoxia inhibited the growth and caused the suspension of egg spawn regardless of PFBs *** regard to the sex endocrine system,7-day PFBs exposure led to an acute stimulation of transcriptional profiles in females,which,subsequently,recovered after the 21-day *** potency of hypoxia to disturb the sex hormones was much stronger than PFBs.A remarkable increase in estradiol concentration was noted in medaka blood after hypoxia *** in sex endocrinology of coexposed fish were largely determined by hypoxia,which drove the formation of an estrogenic *** further enhanced the endocrine disrupting effects of ***,the hepatic synthesis of vitellogenin and choriogenin,two commonly used sensitive biomarkers of estrogenic activity,failed to initiate in response to the estrogen *** to sex endocrine system,disturbances in thyroidal axis by PFBs or hypoxia were relatively ***,the present findings will advance our toxicological understanding about PFBs pollutant under the interference of hypoxia.

关键词： Perfluorobutanesulfonate(PFBs) Aquatic hypoxia Temporal toxicity Combined exposure Endocrine disruption Marine medaka