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Simulating geometrically complex blast scenarios

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Defence technology（防务技术） 2016年第2期12卷 134-146页

作者： Ian G.CULLIS Nikos NIKIFORAKIS Peter FRANKL Philip BLAKELY paul BENNEtt paul GREENWOOD QinetiQ Fort Halstead Sevenoaks Kent T N14 7BP UK Cavendish Laboratory Cambridge University Cambridge CB30LH UK Cambridge Numerical Solutions Ltd Ely Cambridge CB7 5NE UK

the effects of blast waves generated by energetic and non-energetic sources are of continuing interest to the ballistics research *** conflicts are increasingly characterised by asymmetric urban warfare, with improvised explosive devices(IEDs) often playing a dominant role on the one hand and an armed forces requirement for minimal collateral effects from their weapons on the other. these problems are characterised by disparate length- and time-scales and may also be governed by complex physics. there is thus an increasing need to be able to rapidly assess and accurately predict the effects of energetic blast in topologically complex scenarios. to this end, this paper presents a new Qineti Q-developed advanced computational package called EAGLE-Blast, which is capable of accurately resolving the generation, propagation and interaction of blast waves around geometrically complex shapes such as vehicles and buildings. After a brief description of the numerical methodology, various blast scenario simulations are described and the results compared with experimental data to demonstrate the validation of the scheme and its ability to describe these complex scenarios accurately and efficiently. the paper concludes with a brief discussion on the use of the code in supporting the development of algorithms for fast running engineering models.

关键词：爆炸装置复杂场景场景模拟能量来源武装部队时间尺度相互作用形状复杂

tHE RANDOM BAtCH MEtHOD FOR N-BODY QUANtUM DYNAMICS

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Journal of Computational Mathematics 2021年第6期39卷 897-922页

作者： Francois Golse Shi Jin thierry paul Ecole polytechnique CMLS91128 Palaiseau CedexFrance School of Mathematical Sciences Institute of Natural SciencesMOE-LSCShanghai Jiao Tong UniversityShanghai 200240China Sorbonne Universite CNRSUniversite de ParisINRIALaboratoire Jacques-Louis Lions75005 ParisFrance

this paper discusses a numerical method for computing the evolution of large interacting system of quantum *** idea of the random batch method is to replace the total interaction of each particle with the N−1 other particles by the interaction with p≪N particles chosen at random at each time step,multiplied by(N−1)/*** reduces the computational cost of computing the interaction potential per time step from O(N^(2))to O(N).For simplicity,we consider only in this work the case p=1—in other words,we assume that N is even,and that at each time step,the N particles are organized in N/2 pairs,with a random reshuffling of the pairs at the beginning of each time *** obtain a convergence estimate for the Wigner transform of the single-particle reduced density matrix of the particle system at time t that is both uniform in N>1 and independent of the Planck constant h̵.the key idea is to use a new type of distance on the set of quantum states that is reminiscent of the Wasserstein distance of exponent 1(or Monge-Kantorovich-Rubinstein distance)on the set of Borel probability measures on Rd used in the context of optimal transport.

关键词： time-dependent Schrodinger equations Random batch method Mean-field limit Wasserstein distance

DEVELOPMENt OF NEEDLE-BASED MICROENDOSCOPY FOR FLUORESCENCE MOLECULAR IMAGING OF BREASt tUMOR MODELS

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Journal of Innovative Optical Health Sciences 2009年第4期2卷 343-352页

作者： CHAO-WEI CHEN tIFFANY R.BLACKWELL RENEE NAPHAS paul t.WINNARD JR VENU RAMAN KRIStINE GLUNDE YU CHEN Fischell Department of Bioengineering and Electrical and Computer Engineering University of Maryland College ParkMD 20742USA In Vivo Cellular and Molecular Imaging Center(ICMIC)Department of Radiology Johns Hopkins University School of Medicine BaltimoreMD 21205USA§yuchen@umd.edu¶kglunde@mri.jhu.edu

Fluorescence molecular imaging enables the visualization of basic molecular processes such as gene expression,enzyme activity,and disease-specific molecular interactions in vivo using targeted contrast agents,and therefore,is being developed for early detection and in situ characterization of breast *** advances in developing near-infrared fluorescent imaging contrast agents have enabled the specific labeling of human breast cancer cells in mouse model *** synergy with contrast agent development,this paper describes a needle-based fluorescence molecular imaging device that has the strong potential to be translated into clinical breast biopsy *** microendoscopy probe is based on a gradient-index(GRIN)lens interfaced with a laser scanning *** of the imaging performance,including the field-of-view,transverse resolution,and focus tracking characteristics were *** MDA-MB-231 breast cancer xenografts stably expressing the tdtomato red fluorescent protein(RFP)were used to detect the tumor cells in this tumor model as a proof of principle *** further development,this technology,in conjunction with the development of clinically applicable,injectable fluorescent molecular imaging agents,promises to perform fluorescence molecular imaging of breast cancers in vivo for breast biopsy guidance.

关键词： Breast cancer fluorescence molecular imaging microendoscopy optical imaging tdtomato fluorescent protein.

techniques and strategies for regional anesthesia in acute burn care—a narrative review

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Burns & trauma 2021年第1期9卷 383-392页

作者： Clifford C.Sheckter Barclay t.Stewart Christopher Barnes Andrew Walters paul I.Bhalla tam N.Pham Department of Surgery UWMedicine Regional Burn Center at Harborview Medical CenterUniversity ofWashington3259th Ave.SeattleWA 98104USA Harborview Injury Prevention and Research Center University ofWashington401 Broadway.SeattleWA 98122USA Department of Anesthesia and Pain Medicine Harborview Medical Center.University ofWashington3259th Ave.SeattleWA 98104USA

Burn injuries and their treatments result in severe *** traumatic injuries that are characterized by a discrete episode of pain followed by recovery,burn-injured patients endure pain for a prolonged period that lasts through wound closure(*** pain,procedural pain,breakthrough pain,neuropathic pain and itch).Regional anesthesia,including peripheral nerve blocks and neuraxial/epidural anesthesia,offers significant benefits to a multimodal approach in pain treatment.A‘regional-first’approach to pain management can be incorporated into the workflow of burn centers through engaging regional anesthesiologists and pain medicine practitioners in the care of burn patients.A detailed understanding of peripheral nerve anatomy frames the burn clinician’s perspective when considering a peripheral nerve block/*** infra/supraclavicular nerve block provides excellent coverage for the upper extremity,while the trunk can be covered with a variety of blocks including erector spinae plane and quadratus lumborum plane *** lower extremity is targeted with fascia iliaca plane and sciatic nerve blocks for both donor and recipient *** centers that adopt regional anesthesia should be aware of potential complications and contraindications to prevent adverse events,including management of local anesthetic toxicity and epidural *** of anticoagulation around regional anesthesia placement is crucial to prevent hematoma and nerve ***,regional anesthesia can facilitate a better patient experience and allow for early therapy and mobility goals that are hallmarks of burn care and rehabilitation.

关键词： Burn Regional anesthesia Nerve block Epidural Nerve catheter Pain

Survival outcomes and predictors of mortality,re-bleeding and complications for acute severe variceal bleeding requiring balloon tamponade

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World Journal of Hepatology 2022年第8期14卷 1584-1597页

作者： Charlotte Y Keung Aparna Morgan Suong t Le Marcus Robertson paul Urquhart Michael P Swan Department of Gastroenterology Monash HealthMelbourne 3168VictoriaAustralia Department of Gastroenterology Eastern HealthMelbourne 3128VictoriaAustralia Department of Medicine Monash UniversityMelbourne 3168VictoriaAustralia Monash Digital therapeutics and Innovation Laboratory Monash UniversityMelbourne 3168VictoriaAustralia

BACKGROUND Acute severe variceal bleeding(AVB)refractory to medical and endoscopic therapy is infrequent but associated with high *** cohort studies from 1970-1980s no longer represent the current population as balloon tamponade is no longer first-line therapy for variceal bleeding;treatments including vasoactive therapies,intravenous antibiotics,endoscopic variceal band ligation are routinely used,and there is improved access to definitive treatments including transjugular intrahepatic portosystemic ***,only a few studies from the current era exist to describe the practice of balloon tamponade,its outcomes,and predictors with a requirement for further updated *** to describe current management of AVB requiring balloon tamponade and identify the outcomes and predictors of mortality,re-bleeding and *** A retrospective multi-centre cohort study of 80 adult patients across two large tertiary health networks from 2008 to 2019 in Australia who underwent balloon tamponade using a Sengstaken-Blakemore tube(SBt)were included for *** were identified using coding for balloon *** primary outcome of this study was all-cause mortality at 6 wk after the index *** outcomes included re-bleeding during hospitalisation and complications of balloon *** of these outcomes were determined using univariate and multivariate binomial *** the all-cause mortality rates during admission and at 6-,26-and 52 wk were 48.8%,51.2%and 53.8%,*** haemostasis was achieved in 91.3%and re-bleeding during hospitalisation occurred in 34.2%.Independent predictors of 6 wk mortality on multivariate analysis included the Model for Endstage Liver disease(MELD)score(OR 1.21,95%CI 1.06-1.41,P=0.006),advanced hepatocellular carcinoma(OR 11.51,95%CI 1.61-82.20,P=0.015)and re-bleeding(OR 13.06,95%CI 3.06-55.71,Pthere were no relevant predictors of re-bleeding but a larg

关键词： Balloon tamponade Acute variceal bleeding Sengstaken-Blakemore tube Mortality Complications Haemostasis

How Depth is the tibetan Chromite: Experimental Study

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Acta Geologica Sinica(English Edition) 2015年第A2期89卷 35-35页

作者： JIN Zhenmin WU Yao XU Mengjing FEI Yingwei paul t. robinson State Key Lab of Geological Processes and Mineral Resources China University ofGeosciences Wuhan 430074China Geophysical Laboratory Carnegie Institution of Washington Washington DC 20015 USA Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 China

Podiform chromitites are generally lenticular bodies of massive to disseminated chromite typically hosted in mantle peridotites in ophiolites. Most such chromitites are surrounded by envelopes of dunite, a few centimeters to a few meters wide. Based on their textures and compositions, podiform chromitites have been interpreted as magmatic rocks formed as partial melting of mantle peridotite under low-pressure conditions in the upper mantle or by magma mingling and melt-rock reaction.

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等离子体浸没离子注入圆筒内表面的时空尺度

核技术 2002年第9期25卷 709-713页

作者：田修波 D t K Kwok 童洪辉 paul K Chu 香港城市大学

等离子体浸没离子注入与工件外表面的注入不同 ,存在空间和时间上的尺度。研究结果表明 ,由于内腔 ,如内筒的有限尺寸 ,使注入电压的利用率降低 ,同时使内部等离子体快速耗尽 ,对于特定的内筒 ,利用提高注入电压从而提高注入能量只能在... 详细信息

等离子体浸没离子注入与工件外表面的注入不同 ,存在空间和时间上的尺度。研究结果表明 ,由于内腔 ,如内筒的有限尺寸 ,使注入电压的利用率降低 ,同时使内部等离子体快速耗尽 ,对于特定的内筒 ,利用提高注入电压从而提高注入能量只能在一定的电压范围内实现。在典型的外表面注入工艺条件下 ,内表面离子的耗尽速度是惊人的。如在对于直径 2 0cm的圆筒在 30kV、2× 10 15ions/cm3的条件下 ,等离子体耗尽时间仅为 0 .5 5 μs ,这个时间甚至小于多数脉冲电源的上升沿时间。结果表明 ,内部等离子体源的硬件结构可能是一种有效的解决方法。

关键词：时空尺度等离子体浸没离子注入尺度效应圆筒内表面表面改性

New Characterizations of the Dual Spaces of Hardy-amalgam Spaces

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Acta Mathematica Sinica,English Series 2022年第3期38卷 519-546页

作者： Zobo Vincent de paul ABLE Justin FEUtO Laboratoire de Mathématiques Fondamentales UFR Mathématiques et InformatiqueUniversitéFélixHouphouët-Boigny Abidjan-Cocody22B.P.582Abidjan 22Côte d’Ivoire Laboratoire de Mathématiques Fondamentales UFR Mathématiques et InformatiqueUniversitéFélixHouphouët-Boigny Abidjan-Cocody22B.P.1194Abidjan 22Côte d’Ivoire

In this paper,carrying on with our study of the Hardy-amalgam spaces H^((q,p)) and H^((q,p))_(loc)(0terization of their dual spaces whenever 0these ch... 详细信息

In this paper,carrying on with our study of the Hardy-amalgam spaces H^((q,p)) and H^((q,p))_(loc)(0terization of their dual spaces whenever 0these characterizations coincide with those obtained in our earlier papers.

关键词： Amalgam spaces Hardy-amalgam spaces duality Pseudo-differential operators

Helping the First Lady Just Say“No.”

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中国翻译 1996年第5期 62-63页

作者： paul Kennedy

And you think you get a lot of junk mail. Just be glad you don’t have to dcal with what the postman brings First Lady Hillary Rodham Clinton every day.

关键词： Lady No Helping the First Lady Just Say