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Explaining Hong Kong Students’International Achievement in Civic Learning

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Frontiers of Education in China 2016年第3期11卷 299-321页

作者： Kerry j.kennedy LI Lijuan Centre for Governance and Citizenship The Education University of Hong KongHong KongChina Faculty of Education The University of JohannesburgJohannesburgSouth Africa

This study identifies predictors of Hong Kong students’civic *** has adopted a cross-sectional quantitative design using secondary data from the 2009 International Civics and Citizenship Education Study(ICCS 2009;Schulz et al.,2010).Multi-level analysis reveals that most of the variance in student achievement can be accounted for by school level rather than individual level *** background variables are largely insignificant suggesting the resilience of many Hong Kong *** Hong Kong students’achievements in civic learning,a possible explanation is made and implications are developed for both theory and practice.

关键词： political socialization civic learning agents school context multi-level analysis

Assessing the migratory histories, trophic positions, and conditions of lake sturgeon in the St. Croix and Mississippi Rivers using fn ray microchemistry, stable isotopes, and fatty acid profles

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Ecological Processes 2021年第1期10卷 1021-1042页

作者： jefrey R.Ziegeweid Michelle R.Bartsch Lynn A.Bartsch Steven j.Zigler Robert j.kennedy Seth A.Love U.S.Geological Survey California Water Science Center6000 J StPlacer HallSacramentoCA 95819USA. U.S.Geological Survey Upper Midwest Water Science Center2280 Woodale DrMounds ViewMN 55112USA. U.S.Geological Survey Upper Midwest Environmental Sciences Center2630 Fanta Reed RoadLa CrosseWI 54603USA. Division of Fisheries Illinois Department of Natural Resources13608 Fox RoadYorkvilleIL 60560USA.

Background:Reproducing populations of invasive carps(Hypophthalmichthys spp.)could alter aquatic food webs and negatively afect native fshes in the Mississippi National River and Recreation Area(MISS)and the *** National Scenic Riverway(SACN).However,proposed invasive carp barriers may also threaten populations of native migratory fshes by preventing movements of fsh between rivers that are necessary for life history *** this study,nonlethal chemical techniques were used to provide baseline data related to the condition,trophic position,and migratory histories of lake sturgeon(Acipenser fulvescens)captured in the Mississippi and *** ***:Fish length and weight measurements and age estimates determined from pectoral fn rays demonstrated that lake sturgeon from the Mississippi River had greater lengths-at-age compared to sturgeon from the *** ***,length–weight relations were similar for sturgeon from the Mississippi and *** *** sturgeon captured from diferent locations had distinguishable fatty acid signatures,and stable isotope analyses demonstrated that lake sturgeon from the Mississippi River generally feed at a higher trophic level than those in the *** ***-to-calcium ratios(Sr:Ca)from fn ray cross sections indicated that sturgeon captured from the Mississippi River had higher Sr:Ca values than sturgeon captured from the *** River,and natal origins and capture locations were not signifcantly diferent among sturgeon captured within individual *** sturgeon were captured in water with a similar Sr:Ca signature as their natal waters,indicating that there is some separation between populations of lake sturgeon in the *** and Mississippi ***,Sr:Ca data indicated substantial variation in movement patterns among individual lake sturgeon,indicating that populations interact through migrations of individual fsh between ***:Study results provide baseline c

关键词： Fin ray microchemistry Stable isotopes Fatty acids Lake sturgeon St.Croix River Mississippi River National park Strontium Calcium

Helping the First Lady just Say“No.”

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中国翻译 1996年第5期 62-63页

作者： paul kennedy

And you think you get a lot of junk mail. just be glad you don’t have to dcal with what the postman brings First Lady Hillary Rodham Clinton every day.

关键词： Lady No Helping the First Lady just Say

Irritable bowel syndrome: A microbiome-gut-brain axis disorder?

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World journal of Gastroenterology 2014年第39期20卷 14105-14125页

作者： paul j.kennedy john F Cryan Timothy G Dinan Gerard Clarke 1.15 Biosciences Institute Department of Psychiatry Alimentary Pharmabiotic Centre University College Cork Cork Ireland Department of Anatomy and Neuroscience Alimentary Pharmabiotic CentreUniversity College CorkCork Ireland

Irritable bowel syndrome(IBS) is an extremely prevalent but poorly understood gastrointestinal disorder. Consequently, there are no clear diagnostic markers to help diagnose the disorder and treatment options are limited to management of the symptoms. The concept of a dysregulated gut-brain axis has been adopted as a suitable model for the disorder. The gut microbiome may play an important role in the onset and exacerbation of symptoms in the disorder and has been extensively studied in this context. Although a causal role cannot yet be inferred from the clinical studies which have attempted to characterise the gut microbiota in IBS, they do confirm alterations in both community stability and diversity. Moreover, it has been reliably demonstrated that manipulation of the microbiota can influence the key symptoms, including abdominal pain and bowel habit, and other prominent features of IBS. A variety of strategies have been taken to study these interactions, including probiotics, antibiotics, faecal transplantations and the use of germ-free animals. There are clear mechanisms through which the microbiota can produce these effects, both humoral and neural. Taken together, these findings firmly establish the microbiota as a critical node in the gut-brain axis and one which is amenable to therapeutic interventions.

关键词： Irritable bowel syndrome Microbiome Anxiety Tryptophan Abdominal pain Gastrointestinal motility Cognition

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny Cheung jennifer Zhang Kaveh Mirmoeini jpaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

Nanofibers enabled advanced gas sensors:A review

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Advanced Sensor and Energy Materials

Advanced Sensor and Energy Materials 2024年第2期3卷 24-40页

作者： Kening Lang Tianyi Liu Daniel j.Padilla Marriana Nelson Christopher W.Landorf Rishi j.Patel Mark L.Ballentine Alan j.kennedy Wu-Sheng Shih Adam Scotch jiadeng Zhu Smart Devices Brewer Science Inc.SpringfieldMO 65806United States jordan Valley Innovation Center Missouri State UniversitySpringfieldMO 65806United States U.S.Army Corps of Engineers Engineer Research and Development Center3909 Halls Ferry RoadVicksburgMS 39180United States

The advancement of gas sensor technology over the past decades has led to remarkable progress and achievements in pollution control and environmental *** with other sensing materials,electrospun nanofibers have attracted significant attention,which is mainly due to their unique characteristics,including but not limited to high surface area,easy structure design,facile facility setup,multifunctional properties,etc.,making them outstanding candidates for potential applications in this *** review provides an overview of the applications of electrospun nanofibers in gas sensors,concentrating on carbon monoxide,hydrogen,carbon dioxide,hydrogen sulfide,ammonia,nitrogen oxides,oxygen,and volatile organic *** begins with a brief introduction to sensing materials and the advantages of electrospun nanofibers along with their ongoing *** principles and progress of electrospinning are then ***,the corresponding properties of electrospun nanofibers in diverse gas sensors are thoroughly ***,a future vision regarding challenges and perspectives in this area is *** review provides an extensive and comprehensive reference to utilize advanced electrospun nanofibers to generate novel sensors,facilitating their performance in high-demand areas.

关键词： Nanofibers Gas sensors Electrospinning Structure design Environmental protection

对背面电子照射ICCD成象器氧化硅层X射线总剂量的测量

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光电子技术 1981年第2期 69-77+35页

作者： Andrew j.kennedy 刘民孝

现已计算了增强电荷耦合器件（ICCC）中与氧化硅层吸收X射线总剂量有关的电压和电子流量,该器件是以背面电子照射形式工作。计算是依据光谱强度分布和实际器件Si-SiO2界面的纯剂量测量进行的。它表明:微量的入射电子能被转换成产生并透... 详细信息

现已计算了增强电荷耦合器件（ICCC）中与氧化硅层吸收X射线总剂量有关的电压和电子流量,该器件是以背面电子照射形式工作。计算是依据光谱强度分布和实际器件Si-SiO2界面的纯剂量测量进行的。它表明:微量的入射电子能被转换成产生并透过约10μm硅片的X射线,在1万电子伏时约1×10-4,在2万电子伏时约3×10-4。在发射的X射线总能量中,差不多1.5％被100nm的SiO2所吸收。在1.732千电子伏时,X射线能的85—97％是在特性曲线Kα线中。从10μmSi片背面入射,淀积在SiO2内每一个电子的剂量是D=9.7×10-14E（keV）2·2rad（SiO2）/e-cm-2,从13μm硅片背面入射,淀积在SiO2里的每一个电子的剂量D=3.5×10-14E（keV）2·44rad（SiO2）/e-cm-2。在阴天星光亮度条件下(～10-4lux),以10,15,20kV电压工作的标准ICCD的氧化物里,剂量淀积的速率分别是2.3,6.3,12.7rad（SiO2）/小时。对应这些剂量的比率,特别是在工作电压降低的条件下工作时,希望兆拉德淬火的电荷耦合器件在微光ICCD电视摄象管里有长达10万小时的有效工作寿命。

关键词：电荷耦合器件厚度淀积电压电荷转移器件硅片成象剂量用药量吸收曲线 ICCD

Advances in newly developing therapy for chronic hepatitis C virus infection

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Frontiers of Medicine 2014年第2期8卷 166-174页

作者： paul j. Pockros Division of Gastro/Hepatology Scripps Clinic 10666 N Torrey Pines Road N203 La Jolla CA 92067 USA

Chronic hepatitis C virus （HCV） infection afflicts a reported 170 million people worldwide and is often complicated by cirrhosis and hepatocellular carcinoma. Morbidity and mortality are decreased with the successful treatment of chronic HCV infection. Increased understanding of the HCV has allowed further development of new direct-acting antiviral （DAA） agents against the HCV and has also allowed the development of IFN-free oral treatment regimens. In late 2013 the first nucleotide polymerase inhibitor regimen with RBV alone for genotypes 2/3 and in combination with a 12-week regimen of PEG-IFN ＋ RBV for genotypes 1, 4 was approved for use in the US. A number of promising new DAA regimens which are IFN-free are in phase 3 development and the first will likely be approved for use in the US in 2014. The currently approved regimens are discussed in detail and currently available data on future regimens are reviewed herein.

关键词： direct-acting antiviral (DAA) nucleotide polymerase inhibitors protease inhibitors

The Bemisia tabaci Species Complex:Questions to Guide Future Research

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journal of Integrative Agriculture 2012年第2期11卷 187-196页

作者： paul j De Barro CSIRO Ecosystem Sciences Brisbane QLD 4001Australia

Since 2007 we have began to consider the relationships between the different members of the Bemisia tabaci species complex in a more structured and systematic *** of these relationships has been infered from considerations of a portion of the mitochondrial cytochrome oxidase one（mtCOI）*** this is a quite limited approach which would benefit from the consideration of a much greater diversity of genetic material,it is the only publically available data that spans the diversity of the species *** the limitations,the phylogenetic reconstruction that can be derived from this data is useful and can be used as a basis to frame questions and construct testable hypotheses that will form the basis for future *** study uses the largest available mtCOI dataset,consisting of 383 unique mtCOI haplotypes that spans the full diversity of the *** species complex as we currently know it,to make a range of observations which are then used to develop questions as guide for future research.

关键词： mitochondrial cytochrome oxidase one phylogenetic analysis