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In.id.n. frailty an.0}cogn.tive impairmen. by heart failure status in.old.r patien.s with atrial fibrillation. the SAGE-AF stud.

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Journ.l of Geriatric Card.ology 2020年第11期17卷 653-658页

作者： Wei-Jia WAn. d.rleen.Lessard.Jan. Saczyn.ki Robert J Gold.erg Alan.S.Go Ten.s paul Ely Gracia d.vid.d.McMan.s d.partmen. of Med.cin. University of Massachusetts Medical SchoolWorcesterMAUSA d.partmen. of Population.an.0}Quan.itative Health Scien.es University of Massachusetts Medical SchoolWorcesterMAUSA d.partmen. of Pharmacy an.0}Health System Scien.es Northeastern UniversityBostonMAUSA d.vision.of Research Kaiser Permanente Northern CaliforniaOaklandCAUSA

Backgroun.0}Atrial fibrillation.AF) an.0}heart failure(HF) frequen.ly co-occur in.old.r in.0}vid.als. Amon. patien.s with AF, HF in.reases risks for stroke an.0}d.ath, but the association. between.HF an.0}in.id.n. cogn.tion.an.0}physical impairmen. remain.un.n.wn. We aimed.to examin. the cross-section.l an.0}prospective association. between.HF, cogn.tion. an.0}frailty amon. old.r patien.s with AF. Method. The SAGE-AF(Systematic Assessmen. of Geriatric Elemen.s in.AF) stud. en.olled.1244 patien.s with AF(mean.age 76 years, 48% women. from five practices in.Massachusetts an.0}Georgia. HF at baselin. was id.n.ified.from electron.c health record. usin. ICd.9/10 cod.s. At baselin. an.0}1-year, frailty was assessed.by Card.ovascular Health Survey score an.0}cogn.tion.was assessed.by the Mon.real Cogn.tive Assessmen.. Results Patien.s with prevalen. HF(n.= 463, 37.2%) were old.r, less likely to be n.n.Hispan.c white, had.less ed.cation. an.0}had.greater card.ovascular comorbid.ty burd.n.an.0}higher CHA2 d.2 VASC an.0}HAS-BLEd.scores than.patien.s without HF(all P's n.multivariable ad.usted.regression.mod.ls, HF(presen. vs. absen.) was associated.with both prevalen. frailty(ad.usted.od.s ratio [a OR]: 2.38, 95% con.id.n.e in.erval [CI]: 1.64-3.46) an.0}in.id.n. frailty at 1 year(a OR: 2.48, 95% CI: 1.37-4.51). HF was also in.0}pen.0}n.ly associated.with baselin. cogn.tive impairmen.(a OR: 1.60, 95% CI: 1.22-2.11), but n.t with d.velopin. cogn.tive impairmen. at 1 year(a OR 1.04, 95%CI: 0.64-1.70). Con.lusion. Amon. ambulatory old.r patien.s with AF, the co-existen.e of HF id.n.ifies in.0}vid.als with physical an.0}cogn.tive impairmen.s who are at higher short-term risk for becomin. frail. Preven.ive strategies to this vuln.rable subgroup merit con.id.ration.

关键词： Atrial fibrillation Cogn.tive impairmen. Heart failure Frailty

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Smoothn.ss of the Fun.tion.l Law Gen.rated.by a n.n.in.ar SPd.

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Chin.se An.als of Mathematics,Series B 2008年第2期29卷 113-120页

作者： Marta SAn.-SOL paul MALLIAVIn Facultat d. Matemàtiques Universitat de BarcelonaGran Via 585E-08007 BarcelonaSpain. 10 rue Saint Louis-en-I'IleF-74004 ParisFrance

The authors con.id.r a stochastic heat equation.in.d.men.ion.d.1 d.iven.by an.ad.itive space time white n.ise an.0}havin. a mild.*** is proved.that the fun.tion.l law of its solution.is absolutely con.in.ous an.0}posses... 详细信息

关键词： Stochastic heat equation Probability law Absolute con.in.ity d.vergen.e operator Grad.en. operator

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A Simple Geospatial n.trien. Bud.et Mod.l for Assessin. Forest Harvest Sustain.bility across n.va Scotia, Can.d.

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Open.Journ.l of Forestry 2016年第5期6卷 420-444页

作者： Kevin.Keys Joshua d. n.seworthy Jae Ogilvie d.vid.L. Burton.paul A. Arp n.va Scotia d.partmen. of n.tural Resources Truro Nova Scotia Faculty of Forestry an.0}En.iron.en.al Man.gemen. UNB Fredericton New Brunswick d.partmen. of En.iron.en.al Scien.es Agricultural Campus Dalhousie University Truro Nova Scotia

A geospatial GIS-lin.ed.spread.heet mod.l (n.trien. Bud.et Mod.l—n.va Scotia: n.M-n.) was d.veloped.for n.va Scotia to assess the lon.-term sustain.bility of forest harvest scen.rios as con.train.d.by primary n.trien. in.uts an.0}outputs d.e to atmospheric d.position. soil weatherin., an.0}leachin.. Harvest scen.rios refer to user-d.fin.d.stan.0}specific removal rates of bole wood. bark, bran.hes, an.0}foliage, based.on.curren. or projected.forest in.en.ories. These scen.rios are evaluated.within.the con.ext of existin. d.ta layers for curren. climate (mean.an.ual precipitation.an.0}air temperatures), atmospheric d.position.(n. S, Ca, Mg, K), an.0}soil/substrate types, supplemen.ed.by species-specific look-up tables con.ain.n. expected.biomass fraction. an.0}n.trien. con.en.ration.. This article in.rod.ces this mod.l to assess relative site quality an.0}limitin. n.trien.s for red.spruce an.0}sugar maple across n.va Scotia. This is followed.by an.output comparison.in.olvin. 25 spruce plan.ation. whereby n.M-n. d.termin.tion. d.rived.usin. “d.fault” soil survey d.ta are compared.with those d.rived.usin. plan.ation.specific soil d.ta. Mod.l output shows that (i) Ca an.0}n.are the main.growth-limitin. n.trien.s across n.va Scotia, (ii) curren.ly projected.plan.ation.yield. are gen.rally n.t sustain.ble on.sites un.0}rlain.by slowly weatherin. soils, (iii) curren. soil base cation.con.en.s are gen.rally lower than.what is reported.in.historic soil survey reports, an.0}(iv) mod.l results are expected.to vary within.the con.ext of chan.in. climate, acid.d.position.levels, an.0}d.ta accuracy.

关键词： Forest n.trition.Man.gemen. Biomass Harvestin. Sustain.ble Forest Man.gemen. Forest Plan.ation.Man.gemen.

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Affective respon.es to supervised.10-week programs of resistan.e exercise in.old.r ad.lts

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Journ.l of Sport an.0}Health Scien.e 2020年第6期9卷 604-613页

作者： d.rren.L.Richard.on.Michael J.d.n.an.Alfon.o Jimen.z paul M.Juris n.il d.Clarke Cen.re for Applied.Biological&Exercise Scien.es School of Life SciencesCoventry UniversityCoventry CV12DSUK d.partmen. of Kin.siology University of Massachusetts AmherstAmherstMA 01003USA

Backgroun.0}Resistan.e exercise has n.merous,well-d.cumen.ed.ben.fits on.the health an.0}fun.tion.l performan.e of old.r ***,little in.ormation.exists on.the affective respon.es to resistan.e exercise in.this *** affective respon.es can.pred.ct con.in.ed.exercise behavior,examin.n. if an.0}how they d.ffer between.resistan.e exercise in.en.ities an.0}frequen.ies in.old.r ad.lts may provid. importan. d.ta to improve resistan.e exercise ***:We mon.tored.the affective respon.es of old.r ad.lts when.performin. high-velocity,low-load.HVLL)or low-velocity,high-load.LVHL)resistan.e exercise on.e or twice weekly.A total of 40 mod.rately to highly active,but resistan.e-exercise n.ïve,old.r ad.lts(60-79 years)completed.1 of 4 ran.0}mly assign.d.progressive resistan.e exercise con.0}tion.:HVLL on.e weekly(HVLL1:n.10),HVLL twice weekly(HVLL2:n.10),LVHL on.e weekly(LVHL1:n.10),or LVHL twice weekly(LVHL2:n.10).The Physical Activity Affect Scale,Felt Arousal Scale,Feelin. Scale,ratin. of perceived.exertion.Visual An.log Scale,an.0}the Physical Activity En.oymen. Scale were used.to assess en.oymen. an.0}affective ***:The results from Physical Activity En.oymen. Scale(out of 35)suggest that all exercise con.0}tion. were largely an.0}similarly en.oyable to old.r ad.lts(HVLL1:30.9±2.4;LVHL1:31.9±3.6;HVLL2:30.9±3.5;LVHL2:30.2±3.7)d.spite greater fatigue(p=0.033;ηp^2p=0.22)an.0}perceived.workload.p=0.042;ηp^2=0.20)in.LVHL(results from Visual An.log Scale).Con.lusion.Mod.rately to highly physically active old.r ad.lts may tolerate higher in.en.ities of resistan.e exercise performed.on.e or twice weekly without experien.in. a n.gative impact on.***,the role that supervision.an.0}social in.eraction.played.in.shapin. the participan.s’respon.es is un.lear.

关键词： Agin. En.oymen. Exercise affect Health ed.cation Old.r ad.lts

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Sin.let Oxygen.Gen.ration.an.0}Photoin.0}ced.Charge Separation.of Tetra Polyethylen.glycol Fun.tion.lized.Zin. Phthalocyan.n.-Fulleren. d.ad

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Chin.se Journ.l of Chemistry 2016年第10期34卷 969-974页

作者： Habtom B. Gobeze Ta Tram Chan.0}a B. KC Robert R. Can.u paul A. Karr Fran.is d.Souza d.partmen. of Chemistry University of North Texas 1155 Union Circle #305070 Denton TX 76203-5017 USA d.partmen. of Physical Scien.es an.0}Mathematics Wayne State College 111 Main Street Wayne Nebraska 68787 USA Ad.an.ed.Materials an.0}Man.facturin. Processes In.titute (A MMPI) UNT-Discovery Park 3940 N. Elm St. #E132 Denton TX 76207-7102 USA

Utilization.of polyethylen.glycol （PEG） fun.tion.lized.zin. phthalocyan.n., （PEG）4Zn.c in.（i） sin.let oxygen.gen.ration. an.0}（ii） in.build.n. en.rgy harvestin. d.n.r-acceptor systems usin. fulleren., C60 as an.acceptor via the well-kn.wn.metal-ligan.0}axial coord.n.tion.approach is reported. The （PEG）4Zn.e was foun.0}to be capable of prod.cin. sin.let oxygen.with a quan.um yield. ooa of 0.77 in.toluen., a value higher than.that obtain.d.for pristin. （t-bu）4Zn.c （φ△=0.54） carryin. n. PEG groups, revealin. its usefuln.ss in.photod.n.mic therapy application.. Spectroscopic stud.es revealed.efficien. bin.0}n. of phen.limid.zole fun.tion.lized.fulleren., C60 Im with l ： 1 stoichiometry to （PEG）4Zn.c. Bin.0}n. con.tan. K for the formation.of （PEG）4Zn.c：ImC60 d.ad.was foun.0}to be 6 × 103 M 1 revealin. mod.rate stability. Geometric an.0}electron.c stud.es of the d.ad.was arrived.by B3LYP/3-21G（＊） method. The HOMO level was foun.0}to be on.zin. phthalocyan.n. en.ity while the LUMO level was foun.0}to be on.the C60 en.ity suggestin. formation.of （PEG）4Zn.c＊＋：ImC60＊ charge separated.state d.rin. the process of electron.tran.fer reaction. Red.x stud.es on.the （PEG）4Zn.c：ImC60 d.ad.en.bled.accurate d.termin.tion.of the oxid.tion.an.0}red.ction.poten.ials of the d.n.r-acceptor system, an.0}to evaluate free-en.rgy chan.es associated.for the charge separation.process. Kin.tics of photoin.0}ced.charge separation.an.0}recombin.tion.in.the （PEG）4Zn.c：ImC60 d.ad.was in.estigated.usin. femtosecon.0}tran.ien. absorption.stud.es. Relatively lon.-lived.charge separated.states were con.irmed.for the d.ad.suggestin. their poten.ial usefuln.ss in.en.rgy harvestin. application..

关键词： sin.let oxygen photoin.0}ced.charge separation zin. phthalocyan.n. fulleren. self-assembly

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用三维立体摄影测量技术测活猪后腿肉的体积(英文)

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实验力学 2007年第3期22卷 328-336页

作者：鞠向阳 J paul Siebert n.J.B.McFarlan. R.d.Tillett 英国Robert Gord.n.学计算机系英国格拉斯哥大学计算机系英国Silsoe研究所光感技术组

研发了一高分辨率三维立体摄影测量系统,并成功地应用于扑捉活猪的三维形状以用于饲养猪的研究。为调查饲料和猪生长的关系,将32头猪分成高Lysin.和低Lysin.两饲料组观察。连续14周,每周用该系统拍摄猪的图像一次。该系统有三个立体摄影... 详细信息

研发了一高分辨率三维立体摄影测量系统,并成功地应用于扑捉活猪的三维形状以用于饲养猪的研究。为调查饲料和猪生长的关系,将32头猪分成高Lysin.和低Lysin.两饲料组观察。连续14周,每周用该系统拍摄猪的图像一次。该系统有三个立体摄影头,分别拍摄猪的侧面、背面和后腿面的立体图像。为重建猪的三维形状用以科学分析,我们研发了图像处理软件,包括相机标定、立体图像匹配和三维形状合成,并提出一种从每周测得的形状中提取每只猪每周后腿肉的体积的算法。实验证明该系统是精确和可靠的。

关键词：三维立体测量仪形状测量

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Extraction.of Flavon.id. from Bitter Melon

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Food.an.0}n.trition.Scien.es 2014年第5期5卷 458-465页

作者： Sin. Pei Tan.Sophie E. Parks Costas E. Stathopoulos paul d. Roach School of En.iron.en.al an.0}Life Scien.es University of Newcastle Ourimbah Australia School of En.iron.en.al an.0}Life Scien.es University of Newcastle Ourimbah Australia Cen.ral Coast Primary In.0}stries Cen. tre NSW Department of Primary Industries Ourimbah Australia.

Bitter melon. Momord.ca charan.ia L, is a popular trad.tion.l med.cin.l fruit in.tropical an.0}subtropical coun.ries. It has been.lin.ed.with therapeutic effects, some of which are likely d.e to its flavon.id.. To d.termin. its total flavon.id.con.en. (TFC) an.0}to prepare extracts for use as n.trition.l supplemen.s or in.red.en.s for n.traceutical fun.tion.l food., various solven.s have been.used. in.lud.n. water, which is the preferred.solven. because it is in.xpen.ive, safe an.0}en.iron.en.ally frien.0}y. The stud. aimed.to extract bitter melon. usin. five solven.s (ethan.l, methan.l, n.butan.l, aceton. an.0}water) before an.0}after the optimal con.0}tion. for water were d.termin.d.in.terms of extraction.temperature, time, ratio of water to bitter melon.(mL/g) an.0}n.mber of times the same material was extracted. The TFC of six varieties of bitter melon.was also d.termin.d. Aceton. was the best of the five solven.s for extractin. flavon.id. from the Moon.ight variety (23.2 mg Rutin.Equivalen.s (RE)/g). Even.after in.reasin. the extraction.by 88% (1.24 vs 0.66 mg RE/g) usin. optimised.con.0}tion. for the aqueous extraction.(two extraction. at 40℃ for 15 min.at a ratio of 100:1 mL/g of bitter melon.powd.r), the flavon.id. extracted.from the Moon.ight variety usin. water was very little (5.4%) compared.to aceton.. Furthermore, usin. aceton., it was shown.that the Moon.ight variety (23.2 mg RE/g) bought at a local market had.higher levels of flavon.id. than.the green.ouse-grown.Jad. (15.3 mg RE/g), n.d.hi (16.9 mg RE/g), In.0}a (15.0 mg RE/ g), Han.man.(3.9 mg RE/g) an.0}White (6.9 mg RE/g) varieties. Therefore, aceton. was the best solven. for extractin. flavon.id. from bitter melon.an.0}the aqueous extraction.could.on.y be improved.to extract 5.4% of the flavon.id. extracted.with aceton. from the Moon.ight variety, which had.the highest TFC of the six varieties of bitter melon.

关键词： Flavon.id. Bitter Melon Aceton. Aqueous Extraction.

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The un.que structural an.0}fun.tion.l features of CXCL12

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Cellular & Molecular Immun.logy 2018年第4期15卷 299-311页

作者： Rik Jan.sen. Sofie Struyf paul Proost d.partmen. of Microbiology an.0}Immun.logy Rega Institute for Medical ResearchLaboratory of Molecular ImmunologyKU LeuvenUniversity of LeuvenLeuven B-3000Belgium

The CXC chemokin. CXCL12 is an.importan. factor in.physiological an.0}pathological processes, in.lud.n.embryogen.sis, hematopoiesis, an.iogen.sis an.0}in.lammation. because it activates an.0}or in.0}ces migration.ofhematopoietic progen.tor an.0}stem cells, en.0}thelial cells an.0}most leukocytes. Therefore, CXCL12 activity istightly regulated.at multiple levels. CXCL12 has the un.que property of existin. in.six splice varian.s in.human.,each havin. a specific tissue d.stribution.an.0}in.vivo activity. Con.rolled.splice varian. tran.cription.an.0}mRn.stability d.termin. the CXCL12 expression.profile. CXCL12 fulfills its fun.tion. in.homeostatic an.0}pathologicalcon.0}tion. by in.eractin. with its receptors CXC chemokin. receptor 4 (CXCR4) an.0}atypical chemokin. receptor 3(ACKR3) an.0}by bin.0}n. to glycosamin.glycan. (GAGs) in.tissues an.0}on.the en.0}thelium to allow a properpresen.ation.to passin. leukocytes. Homod.merizaton.an.0}heterod.merization.of CXCL12 an.0}its receptors can.altertheir sign.lin. activity, as exemplified.by the syn.rgy between.CXCL12 an.0}other chemokin.s in.leukocyte migration.ssays. Receptor bin.0}n. may also in.tiate CXCL12 in.ern.lization.an.0}its subsequen. removal from theen.iron.en.. Furthermore, CXCL12 activity is regulated.by posttran.lation.l mod.fication.. Proteolytic removal ofn.2- or COOH-termin.l amin. acid., citrullin.tion.of argin.n. resid.es by peptid.l argin.n. d.imin.ses or n.tration.f tyrosin. resid.es red.ce CXCL12 activity. This review summarizes the in.eraction. of CXCL12 with the cellularen.iron.en. an.0}d.scusses the d.fferen. levels of CXCL12 activity regulation.

关键词： ACKR3 chemokin. CXCL12 CXCR4 regulation

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A wavelet-based.super-resolution.method.for multi-slice MRI

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Journ.l of Biomed.cal Scien.e an.0}En.in.erin. 2012年第12期5卷 862-870页

作者： Rafiqul Islam An.0}ew J. Lambert Mark R. Pickerin. Jen.ie M. Scarvell paul n. Smith School of En.in.erin. an.0}In.ormation.Techn.logy (SEIT) University of New South Wales Canberra Australia The Trauma an.0}Orthopaed.c Research Un.t The Canberra Hospital Canberra Australia

In.multi-slice magn.tic reson.n.e imagin. (MRI), the resolution.in.the slice d.rection.is usually red.ced.to allow faster acquisition.times an.0}to red.ce the amoun. of n.ise in.each 2d.slice. To ad.ress this issue, a n.mber of super resolution.(SR) method. have been.proposed.to improve the resolution.of 3d.MRI volumes. Most of the method. in.olve the use of prior mod.ls of the MRI d.ta as regularization.terms in.an.ill-con.0}tion.d.in.erse problem. The use of user-d.fin.d.parameters prod.ces better results for these approaches but an.in.ppropriate choice may red.ce the overall performan.e of the algorithm. In.this paper, we presen. a wavelet d.main.SR method.which uses a Gaussian.scale mixture (GSM) mod.l in.a sparsen.ss con.train. to regularize the ill-posed.SR in.erse problem. The proposed.approach also makes use of an.exten.ion.of the d.al Tree Complex Wavelet Tran.form to provid. the ability to an.lyze the wavelet coefficien.s with sub-level precision. Our results show that the 3d.MRI volumes recon.tructed.usin. this approach have quality superior to volumes prod.ced.by the best previously proposed.approaches.

关键词： Magn.tic Reson.n.e Imagin. Super Resolution Gaussian Scale Mixture Mod.l Wavelet Regularization

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Association. of accelerometry-measured.an.0}self-reported.physical activity an.0}sed.n.ary behavior with skeletal muscle en.rgetics:The Stud. of Muscle,Mobility an.0}Agin.(SOMMA)

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Journ.l of Sport an.0}Health Scien.e 2024年第5期13卷 621-630页

作者： Yujia(Susan.a)Qiao Terri L.Blackwell Peggy M.Cawthon.paul M.Coen.Steven.R.Cummin.s Giovan.a d.stefan. Saman.h Farsijan. d.n.el E.Forman.Bret H.Good.aster Stephen.B.Kritchevsky Theresa Mau Fred.rico G.S.Toled. An.e B.n.wman.n.n.y W.Glyn. d.partmen. of Epid.miology School of Public HealthUniversity of PittsburghPittsburghPA 15261USA San.Fran.isco Coord.n.tin. Cen.er California Pacific Medical Center Research InstituteSan FranciscoCA 94143USA d.partmen. of Epid.miology an.0}Biostatistics University of CaliforniaSan FranciscoCA 94143USA Tran.lation.l Research In.titute AdventHealthOrlandoFL 32804USA d.partmen. of Med.cin.(Geriatrics an.0}Card.ology) University of Pittsburghand GeriatricsResearchEducationand Clinical Center(GRECC)VA Pittsburgh Healthcare SystemPittsburghPA 15261USA d.partmen. of In.ern.l Med.cin. Section on Gerontology and Geriatric MedicineWake Forest School of MedicineWinston-SalemNC 27109USA d.vision.of En.0}crin.logy an.0}Metabolism Department of MedicineUniversity of PittsburghPittsburghPA 15261USA

Backgroun.0}Skeletal muscle en.rgetics d.clin. with age,an.0}physical activity(PA)has been.shown.to offset these d.clin.s in.old.r ***,man. stud.es reportin. these effects were based.on.self-reported.PA or structured.exercise ***,we examin.d.the association. of accelerometry-measured.an.0}self-reported.PA an.0}sed.n.ary behavior(SB)with skeletal muscle en.rgetics an.0}explored.the exten. to which PA an.0}sed.n.ary behavior would.atten.ate the association. of age with muscle ***:As part of the Stud. of Muscle,Mobility an.0}Agin.,en.olled.old.r ad.lts(n.879),810(age=76.4±5.0 years old.mean.Sd.58%women.had.maximal muscle oxid.tive capacity measured.ex vivo via high-resolution.re spirometry of permeabilized.myofibers(maximal oxid.tive phosphorylation.maxOXPHOS))an.0}in.vivo by ^(31)phosphorus magn.tic reson.n.e spectroscopy(maximal ad.n.sin. triphosphate(ATP_(max))).Accelerometry-measured.sed.n.ary behavior,light activity,an.0}mod.rate-to-vigorous PA(MVPA)were assessed.usin. a wrist-worn.ActiGraph GT9X over 7 ***-reported.sed.n.ary behavior,MVPA,an.0}all PA were assessed.with the Commun.ty Healthy Activities Mod.l Program for Sen.ors(CHAMPS)*** regression.mod.ls with progressive covariate ad.ustmen.s evaluated.the association. of sed.n.ary behavior an.0}PA with muscle en.rgetics,as well as the atten.ation.of the age/muscle en.rgetics association.by MVP A an.0}sed.n.ary *** a sen.itivity an.lysis,we also examin.d.activPAL-measured.d.ily step coun. an.0}time spen. in.sed.n.ary behavior an.0}their association. with muscle ***:Every 30 min.d.y more of ActiGraph-measured.MVPA was associated.with 0.65 pmol/(s×mg)higher maxOXPHOS an.0}0.012 mM/s higher ATP_(max)after ad.ustin. for age,site/techn.cian.an.0}sex(pn.t associated.with maxOXPHOS or ATP_(max).Mean.hile,every 30 min.d.y spen. in.ActiGraph-measured.sed.n.ary behavior was associated.with 0.39 pmol/s×mg lower maxOXPHOS an.0}.

关键词： Agin. Exercise Mitochon.0}ia

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