检索结果-南通市图书馆

世界核心医学期刊文摘（眼科学分册） 2005年第7期1卷 59-60页

作者： Apushkin M.A. Fishman G.A. janowicz M.j. 王海燕 UIC Eye Center University of Illinois at Chicago 1855West Taylor Street Chicago IL 60612 United States

Purpose: To evaluate and correlate findings obtained by optical coherence tomography (OCT) imaging with visual acuity (VA) andmacular lesions in patientswith X- linked retinoschisis (XLRS). Design: Prospective comparative case series. Participants: Thirty- one patients with confirmed XLRS. Methods: Best- corrected VA was determined using Early Treatment Diabetic Retinopathy Study charts, and a dilated funduscopic examination was performed on all patients. For all patients, the macula in each eye was OCT imaged. A correlation between VA, macular presentation, and OCT images was determined. Main Outcome Measures: Analysis of findings on OCT images, including foveal thickness and the area of macular cystic- appearing lesions, and their correlation with VA. Results: Twenty- five patientswith funduscopically evident cysticappearing macular lesions demonstrated cysticlike spaces on OCT images. No statistically significant correlation was observed between the macular area of the cysticlike spaces, foveal thickness, and VA. Three patients with no funduscopic or OCT evidence of foveal cysts demonstrated thinning of the fovea on OCT images and more extensive reduction of their VA. Retinal papillomacular bundle nerve fiber layer thickness on OCT images showed no significant difference between control and patient groups. Conclusions: In XLRS patients with cystic- appearing macular lesions, there was a lack of correlation between VA, foveal thickness, and cystic area. The anatomical appearance of smaller perifoveal cysts on OCT imaging was most consistent with their location being primarily within the inner nuclear layer of the retina. In older patients, macular cysts were no longer apparent clinically or by OCT imaging, and foveal thicknesswas reduced. The findings on OCT images are consistent with the hypothesis of a primary Mü ller cell defect in patients with XLRS.

关键词： OCT结果 X连锁囊样眼底检查中心凹内核层神经纤维层眼底镜比较性解剖形态

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

背阔肌皮瓣乳房再造术设计算法（摘要）

引用

中国美容整形外科杂志 2011年第3期22卷 I0020-I0020页

作者： Alan j. Durkin Yvonne N. Pierpont Shitel Patel M. Lance Tavana M. Georgina Uberti wyatt G. Payne David j. Smith paul D. Smith 魏峰(译) 高景恒(译) 张晨(译) 美国佛罗里达州南佛罗里达大学外科部整形外科中心松树湾退伍军人医疗事务部组织再生与整复中心佛罗里达大学尚兹医院整形外科《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科

目的肿瘤外科医师对手术技术的改进，使乳腺癌切除术后残留的乳房形态得到改善。以背阔肌皮瓣行乳房再造术效果肯定。本研究将评估不同类型的用于乳房再造术的背阔肌皮瓣的皮岛设计，寻找一种广泛用于修复各种乳腺癌切除术后缺损的背阔... 详细信息

目的肿瘤外科医师对手术技术的改进，使乳腺癌切除术后残留的乳房形态得到改善。以背阔肌皮瓣行乳房再造术效果肯定。本研究将评估不同类型的用于乳房再造术的背阔肌皮瓣的皮岛设计，寻找一种广泛用于修复各种乳腺癌切除术后缺损的背阔肌皮瓣设计算法设计原则。方法本研究回顾性分析自2001年2月至2005年4月收治的单侧或双侧乳腺癌切除术后背阔肌皮瓣乳房再造患者的临床资料。在掌握如下情况的前提下进行再造手术：①术前组织是否经放疗处理；②体质量指数是否〉30；③当前有无吸烟习惯；④之前是否做过腹腔骨盆手术；⑤患者的要求。并对患者依据缺损形式进行分组：①乳房下皱襞完整但皮肤量不足；②乳房下皱襞完整且皮肤量足够；③乳房下皱襞缺损伴或不伴皮肤量不足。根据缺损的不同。设计不同的皮岛来优化手术效果，并减少供区瘢痕形成。结果本组患者54例，共应用64块背阔肌皮瓣行乳房再造术。各组间术后外观美学效果及供区瘢痕形成情况不同。结论本研究制定了一种背阔肌皮瓣乳房再造术的相关算法设计模式。通过对乳腺癌切除术后缺损的准确评价，在利用背阔肌皮瓣进行乳房再造术时，可定向切取皮岛，减少供区瘢痕形成，提高美学效果，获得疗效持久、外观自然、美观的乳房。

关键词：乳房再造术背阔肌皮瓣皮岛设计算法双侧乳腺癌乳房下皱襞术后缺损摘要

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The use of shared haplotype length information for pedigree reconstruction in asexually propagated outbreeding crops, demonstrated for apple and sweet cherry

引用

Horticulture Research 2021年第1期8卷 2785-2797页

作者： Nicholas P.Howard Cameron Peace Kevin A.T.Silverstein Ana Poets james j.Luby Stijn Vanderzande Charles-Eric Durel Helene Muranty Caroline Denance Eric van de weg Institut fur Biologie und Umweltwissenschaften Carl von Ossietzky UniversityOldenburgGermany Department of Horticultural Science University of MinnesotaSt.PaulMNUSA Department of Horticulture and Landscape Architecture Washington State UniversityPullmanWashingtonWAUSA Minnesota Supercomputing Institute University of MinnesotaMinneapolisMNUSA Universited’Angers Institut AgroINRAEIRHSSFR 4207 QuaSaVBeaucouzeFrance Plant Breeding Wageningen University and ResearchWageningenThe Netherlands

Pedigree information is of fundamental importance in breeding programs and related genetics ***,many individuals have unknown *** methods to identify and confirm direct parent–offspring relationships are routine,those for other types of close relationships have yet to be effectively and widely implemented with plants,due to complications such as asexual propagation and extensive *** objective of this study was to develop and demonstrate methods that support complex pedigree reconstruction via the total length of identical by state haplotypes(referred to in this study as“summed potential lengths of shared haplotypes”,SPLoSH).A custom Python script,HapShared,was developed to generate SPLoSH data in apple and sweet *** was used to establish empirical distributions of SPLoSH data for known relationships in these *** distributions were then used to estimate previously unknown *** studies in each crop demonstrated various pedigree reconstruction scenarios using SPLoSH *** cherry,a full-sib relationship was deduced for‘Emperor Francis,and‘Schmidt’,a half-sib relationship for‘Van’and‘windsor’,and the paternal grandparents of‘Stella’were *** apple,29 cultivars were found to share an unknown parent,the pedigree of the unknown parent of‘Cox’s Pomona’was reconstructed,and‘Fameuse’was deduced to be a likely grandparent of‘McIntosh’.Key genetic resources that enabled this empirical study were large genome-wide SNP array datasets,integrated genetic maps,and previously identified pedigree *** with similar resources are also expected to benefit from using HapShared for empowering pedigree reconstruction.

关键词： Python breeding crops

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

单臂和taylor外固定治疗老年GustiloⅡ型胫腓骨骨折患者临床疗效及有限元分析

引用

中华老年医学杂志 2018年第9期37卷 1004-1008页

作者：汪松孙倩冯硕查国春史进耿猛徐州医科大学附属医院骨科徐州221006 徐州市第一人民医院老年二科徐州221006

目的比较单臂外固定支架（UF）和taylor外固定支架（TF）治疗老年GustiloⅡ型胫腓骨骨折患者临床疗效和生物力学性能。方法回顾性分析2012年1月至2015年8月采用uF和TF固定治疗的86例开放性胫腓骨骨折患者资料。根据骨外固定不同方式分为... 详细信息

目的比较单臂外固定支架（UF）和taylor外固定支架（TF）治疗老年GustiloⅡ型胫腓骨骨折患者临床疗效和生物力学性能。方法回顾性分析2012年1月至2015年8月采用uF和TF固定治疗的86例开放性胫腓骨骨折患者资料。根据骨外固定不同方式分为2组：UF组49例，TF组37例，比较两组患者的临床效果。在充分验证有限元模型有效性的前提下，对UF和TF分别进行轴向、扭转和弯曲试验，其中弯曲实验为环绕有限元模型每隔10。进行评估。结果uF组患者手术时间为（43．2±11．7）min，术中出血量为（32．1±13．8）ml，低于TF组患者[（63．6±9．8）min，（57．6±23．1）m1]。所有患者术后获8-31个月（平均13．8个月）随访。UF组患者愈合时间为（4．6±1.7）个月，术后并发症发生率为4．5％（9／201），均优于TF组患者[（5．7±2．1）个月，12．0％（14／117）]（P〈0．05）。uF轴向刚度341．47N／m，扭转刚度80.00 Nm／deg，均高于TF（226．83N／m，72．00 Nm／deg）；uF组弯曲刚度为210．00-430．00N／m，变化幅度高于TF组（242．00-287．00N／m）。结论uF外固定支架治疗开放性胫腓骨骨折操作简单，更符合胫腓骨的生物力学特性，具有较好的抗压、抗弯和防旋能力。相对于taylor外固定支架，单臂支架更有利于骨折愈合，具有明显优势。

关键词：骨折固定术胫骨骨折腓骨骨折有限元分析

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Turbulent hydrodynamics experiments in high energy density plasmas： scientific case and preliminary results of the TurboHEDP project

引用

High Power Laser Science and Engineering 2018年第3期6卷 50-64页

作者： A. Casner G. Rigon B. Albertazzi Th. Michel T. Pikuz A. Faenov P. Mabey N. Ozaki Y. Sakawa T. Sano j. Ballet P. Tzeferacos D. Lamb E. Falize G. Gregori M. Koenig Universite de Bordeaux-CNRS-CEA CELIA (CEntre Lasers Intenses et Applications) UMR 5107 F-33405 Talence France LULI- CNRS Ecole Polytechnique CEA Universite Paris-Saclay UPMC Univ Paris 06 : Sorbonne Universites -F-91128 Palaiseau cedex France ENS Lyon Universite de Lyon CHELS 69342 Lyon France Open and Transdisciplinary Research Initiatives Osaka University Suita Osaka 565-0871 Japan joint Institute for High Temperature RAS Moscow 125412 Russia Graduate School of Engineering Osaka University Suita Osaka 565-0871 Japan Institute of Laser Engineering Osaka University Suita Osaka 565-0871 Japan Laboratoire AIM CEA-IRFU/CNRS/Universite Paris Diderot Departement d'Astrophysique CEA Saclay F-91191 Gif sur Yvette France Flash Center for Computational Science University of Chicago USA CEA DAM DIF F-91297 Arpajon France Clarendon Laboratory University of Oxford Parks Road Oxford OX1 3PU UK

The physics of compressible turbulence in high energy density(HED) plasmas is an unchartered experimental *** of compressible and radiative flows relevant for astrophysics rely mainly on subscale parameters. Therefore,we plan to perform turbulent hydrodynamics experiments in HED plasmas(TurboHEDP) in order to improve our understanding of such important phenomena for interest in both communities: laser plasma physics and astrophysics. we will focus on the physics of supernovae remnants which are complex structures subject to fluid instabilities such as the Rayleigh–taylor and Kelvin–Helmholtz instabilities. The advent of megajoule laser facilities, like the National Ignition Facility and the Laser Megajoule, creates novel opportunities in laboratory astrophysics, as it provides unique platforms to study turbulent mixing flows in HED plasmas. Indeed, the physics requires accelerating targets over larger distances and longer time periods than previously achieved. In a preparatory phase, scaling from experiments at lower laser energies is used to guarantee the performance of future Mj experiments. This subscale experiments allow us to develop experimental skills and numerical tools in this new field of research, and are stepping stones to achieve our objectives on larger laser facilities. we review first in this paper recent advances in high energy density experiments devoted to laboratory astrophysics. Then we describe the necessary steps forward to commission an experimental platform devoted to turbulent hydrodynamics on a megajoule laser facility. Recent novel experimental results acquired on LULI2000, as well as supporting radiative hydrodynamics simulations, are presented. Together with the development of LiF detectors as transformative X-ray diagnostics, these preliminary results are promising on the way to achieve micrometric spatial resolution in turbulent HED physics experiments in the near future.

关键词： high energy density physics inertial confinement fusion laboratory astrophysics plasmas astrophysics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

未经治疗的血管瘤：生长模式及残余病灶

引用

中国美容整形外科杂志 2012年第3期23卷 I0011-I0015页

作者： Constantijn G. Bauland Thomas H. Luning jeroen M. Smit Clark j. Zeebregts paul H. M. Spauwen 魏峰高景恒袁继龙石杰张晨荷兰奈梅亨拉德博的大学奈梅亨医学中心Canisius-Wilhelmina医院整形再造外科埃因霍温Catharina医院整形再造外科格罗宁根大学格罗宁根医学中心外科部血管外科《中国美容整形外科杂志》编辑部辽宁省人民医院整形外科大连大学附属新华医院整形外科

背景与目的婴幼儿血管瘤具有快速增长及可能损毁容貌的特性，因此，应给予重视。本研究旨在探讨血管瘤的生长模式和残余病灶的危险因素。方法对1985—2000年间临床监护、未经任何治疗的血管瘤患儿进行随访调查研究。从病案资料中提取相... 详细信息

背景与目的婴幼儿血管瘤具有快速增长及可能损毁容貌的特性，因此，应给予重视。本研究旨在探讨血管瘤的生长模式和残余病灶的危险因素。方法对1985—2000年间临床监护、未经任何治疗的血管瘤患儿进行随访调查研究。从病案资料中提取相关信息。访问患儿（或其家长）完成问卷调查表，请患儿到我们的门诊，对问卷调查表的相关内容进行讨论，并对患儿行体格检查。对血管瘤的各生长阶段情况进行记录，创建各生长阶段时问轴，如果有残余病灶，对其进行评估。结果共对97例患儿的137处血管瘤病灶进行评估。48％患儿有前期病变。8个月时瘤体尺寸达到最大。消退期平均在患儿2岁时开始，并于平均4岁时结束。69％患儿有残余病灶。表浅结节状血管瘤的残余病灶（74％）明显比深层血管瘤（25％）多（P〈0．001；优势率8．4；95％可信区间2．4～29．1）。97％患儿出现因感染、溃疡、出血未经治疗而产生的瘢痕。结论血管瘤残余病灶会引起表皮损伤。血管瘤的生长模式与形成残余病灶的危险因素问无关联。这一结论将有助于更详细地预知血管瘤的预后情况，并将有助于判别哪些患儿需要治疗，哪些不需要。

关键词：婴幼儿血管瘤生长模式病灶残余治疗问卷调查表生长阶段危险因素

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高超声速飞行器表面热流测试方法

高超声速飞行器表面热流测试方法

引用

第八届全国实验流体力学学术会议

作者：赵学军杨乐天金鑫 j.I.Frankel 中国航天空气动力技术研究院田纳西大学

本文提出了可用于高超声速飞行试验热流测量的新方法。采用内埋式热电偶,从时间域的观点出发,估算一维几何体的表面温度和表面热流。本方法的关键点在于正确理解内埋热电偶处的温度和热流关系,并建立其积分关系式,同时采用低通、高斯数... 详细信息

本文提出了可用于高超声速飞行试验热流测量的新方法。采用内埋式热电偶,从时间域的观点出发,估算一维几何体的表面温度和表面热流。本方法的关键点在于正确理解内埋热电偶处的温度和热流关系,并建立其积分关系式,同时采用低通、高斯数字滤波的方法获得高精度的热流。采用简单的有限微分方法得到滤波后的温度和热流对时间的导数,然后使用taylor展开估算表面热流。

关键词：高超声速热流内埋式热电偶滤波温度热积分关系式

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

使用Symmetry近端吻合器行冠状动脉搭桥术的术中及中期血管造影结果

引用

世界核心医学期刊文摘（心脏病学分册） 2005年第4期1卷 58-59页

作者： Bergsland j. Hol P. K. Lings P. S. 刘少伟

The objective of this study was to investigate the patency in saphenous vein c oronary bypass grafts in which the proximal anastomoseswere performedwith automa tic connector devices or with a traditional suture technique. Forty-six patient s underwent coronary artery bypass grafting without cardiopulmonary bypass by us ing one thoracic graft and one or more saphenous vein grafts. Grafts were attach ed to the aorta with a Symmetry connector(St jude Medical, Inc, St paul, Minn) i n 23 patients, and partial occlusion of the aorta and sutured anastomoses were u sed in 23 other patients. Grafts were studied intraoperatively with transit time flowmetry and angiography and revised if necessary. Angiography was repeated af ter 3 to 5 months. Intraoperative graft patency did not differ between the 2 gro ups. Follow-up angiography demonstrated excellent thoracic graft patency. Vein graft patency decreased to 50%in the Symmetry group, whereas it was 90%in the suture group (P=. 01). Twenty-five percent of the Symmetry grafts had significa nt stenosis in the connector. Saphenous vein grafts anastomosed to aorta with th e Symmetry proximal connector have low intermediate patency compared with those with traditionally sutured anastomoses. we do not recommend the routine use of t his device in coronary artery bypass operations.

关键词：冠状动脉搭桥术 Symmetry 吻合器近端血管造影移植血管旁路移植升主动脉移植静脉动脉吻合

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

On-chip beam rotators,adiabatic mode converters,and waveplates through low-loss waveguides with variable cross-sections

引用

Light(Science & Applications) 2022年第8期11卷 1876-1890页

作者： Bangshan Sun Fyodor Morozko Patrick S.Salter Simon Moser Zhikai Pong Raj B.Patel Ian A.walmsley Mohan wang Adir Hazan Nicolas Barré Alexander jesacher julian Fells Chao He Aviad Katiyi Zhen-Nan Tian Alina Karabchevsky Martin j.Booth Department of Engineering Science University of OxfordOxfordOX13PJUK School of Electrical and Computer Engineering Ben-Gurion University of the NegevP.O.B.653Beer-Sheva8410501Israel Institute of Biomedical Physics Medical University of InnsbruckMüllerstraße 446020InnsbruckAustria Ultrafast Quantum Optics group Department of PhysicsImperial College LondonLondonUK Department of Physics University of OxfordOxfordUK Erlangen Graduate School in Advanced Optical Technologies(SAOT) Friedrich-Alexander-University Erlangen-NürnbergPaul-Gordan-Straße 691052ErlangenGermany State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun130012China

Photonics integrated circuitry would benefit considerably from the ability to arbitrarily control waveguide cross-sections with high precision and low loss,in order to provide more degrees of freedom in manipulating propagating ***,we report a new method for femtosecond laser writing of optical-fiber-compatible glass waveguides,namely spherical phase-induced multicore waveguide(SPIM-wG),which addresses this challenging task with three-dimensional on-chip light *** in the heating regime with high scanning speed,precise deformation of cross-sections is still achievable along the waveguide,with shapes and sizes finely controllable of high resolution in both horizontal and vertical transversal *** observed that these waveguides have high refractive index contrast of 0.017,low propagation loss of 0.14 dB/cm,and very low coupling loss of 0.19 dB coupled from a single-mode ***-wG devices were easily fabricated that were able to perform on-chip beam rotation through varying angles,or manipulate the polarization state of propagating light for target *** also demonstrated SPIM-wG mode converters that provide arbitrary adiabatic mode conversion with high efficiency between symmetric and asymmetric nonuniform modes;examples include circular,elliptical modes,and asymmetric modes from ppKTP(periodically poled potassium titanyl phosphate)waveguides which are generally applied in frequency conversion and quantum light *** inside optical glass,these waveguides and devices have the capability to operate across ultra-broad bands from visible to infrared *** compatibility with optical fiber also paves the way toward packaged photonic integrated circuitry,which usually needs input and output fiber connections.

关键词： waveguide waveguides polarization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

5%咪喹莫特乳膏治疗浅表性基底细胞癌:欧洲Ⅲ期随机、赋形剂对照研究结果

引用

世界核心医学期刊文摘（皮肤病学分册） 2005年第8期1卷 19-20页

作者： Schulze H.- j. Cribier B. Requena L. 李政霄 Fachklinik Hornheide Dorbaumstr. 300 48157 M¨ unster Germany

Background: Imiquimod is an immune response modifier that acts through toll- like receptor 7 to induce cytokine production and a subsequent innate and adaptive cell- mediated immune response. Clinical studies have demonstrated clinical and histological clearance of superficial basal cell carcinoma (sBCC) after treatment with imiquimod 5% cream. Objectives: To evaluate the safety and clinical efficacy of imiquimod (Aldara.; 3M Pharmaceuticals, St paul, MN, U.S.A.) 5% cream for the treatment of sBCC in a multicentre, randomized, parallel, vehicle- controlled, double- blind, phase III clinical study conducted at 26 centres in Europe. Methods: Subjects who had at least one histologically confirmed sBCC tumour were randomized to apply imiquimod or vehicle cream to the target tumour once daily, seven times, per week (7 x/week)for 6 weeks. The target tumour location was identified with an indelible ink mark before treatment initiation. The treated tumour site was clinically assessed for treatment response at 12 weeks post- treatment and was then excised for histological evaluation. Efficacy assessments included the composite response rates (proportion of subjects with clinical and histological clearance) and response rates solely based on histology (proportion of subjects with histological clearance). Safety assessments, which included adverse events and scoring of local skin reactions (LSRs), were carried out throughout the study. Results: In total, 166 subjects were enrolled in this study. For the intent- to- treat dataset, there was a statistically significant difference between imiquimod and vehicle groups for both composite clearance rates (clinical and histological assessments) and histological clearance rates. Composite clearance was demonstrated in 77% and 6% of subjects treated with imiquimod and vehicle cream, respectively. Histological clearance was demonstrated in 80% and 6% of subjects treated with imiquimod and vehicle cream, respectively. The most frequently

关键词：咪喹莫特组织学检查赋形免疫应答局部活检清除率用药反应细胞调节细胞因子皮肤反应

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：