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Fungal diversity notes 1036-1150:taxonom.c and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2019年第3期96卷 1-242页

作者： Kevin D.Hyde Danushka S.Tennakoon Rajesh Jeewon DJayaram. Bhat Sajeewa S.N.m.harachchikum.ura Walter Rossi m.rco Leonardi Hyang Burm.Lee Hye Yeon m.n Jos Houbraken Thuong T.T.Nguyen Sun Jeong Jeon Jens Christian Frisvad Dhanushka N.Wanasinghe Robert Lucking Andre Aptroot m.rcela E.S.Caceres Sam.ntha C.Karunarathna Sinang Hongsanan Rungtiwa Phookam.ak Nim.li Ide Silva Kasun m.Tham.ugala Ruvishika S.Jayawardena Indunil C.Senanayake Saranyaphat Boonm.e Jie Chen Zong-Long Luo Chayanard Phukham.akda Olinto L.Pereira Vanessa P.Abreu Andre Wilson Cam.os Rosado Buyck Bart Em.le Randrianjohany Vale rie Hofstetter Tatiana B.Gibertoni Adriene m.yrada Silva Soares Helio Longoni Plautz Jr Helen m.ria Pontes Sotao William.Kalhy Silva Xavier Jadson Diogo Pereira Bezerra Thays Gabrielle Linsde Oliveira Cristina m.riade Souza-m.tta Oliane m.ria Correia m.galhaes Digvijayini Bundhun Dulanjalee Harishchandra Ishara S.m.nawasinghe Wei Dong Sheng-Nan Zhang Dan-Feng Bao m.lan C.Sam.rakoon Dhandevi Pem.Anuruddha Karunarathna Chuan-Gen Lin Jing Yang Rekhani H.Perera Vinit Kum.r Shi-Ke Huang m.nika C.Dayarathne Anusha H.Ekanayaka Subashini C.Jayasiri Yuanpin Xiao Sirinapa Konta Tuula Niskanen Kare Liim.tainen Yu-Cheng Dai Xiao-Hong Ji Xue-m.i Tian Arm.n m.sic Sanjay K.Singh Kunthida Phutthacharoen Lei Cai Touny Sorvongxay Vinodhini Thiyagaraja Chada Norphanphoun Napalai Chaiwan Yong-Zhong Lu Hong-Bo Jiang Jin-Feng Zhang Pranam. D.Abeywickram. Janith V.S.Aluthm.handiram.Rashika S.Brahm.nage m.ng Zeng Thilini Chethana Deping Wei m.rtina Reblova Jacques Fournier Jana Nekvindova Renan do Nascim.nto Barbosa Jose Ewerton Felintodos Santos Neiva Tintide Oliveira Guo-Jie Li Dam.en Ertz Qiu-Ju Shang Alan J.L.Phillips Chang-Hsin Kuo Erio Cam.oresi Tim.r S.Bulgakov Saisam.rn Lum.ong E.B.Gareth Jones Putarak Chom.unti Eleni Gentekaki Frank Bungartz Xiang-Yu Zeng Sally Fryar Zdenko Tkalcec Junm.n Liang Guangshuo Li Ting-Chi Wen Paras Nath Singh Yusufjon Gafforov Itthayakorn Prom.uttha Erandi Yasanthika Ishani D.Goonasekara Rui-Lin Zhao Qi Zhao paul m Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand East and Central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanPeople’s Republic of China Departm.nt of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand m.shroom.Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Departm.nt of Plant m.dicine National Chiayi University300 Syuefu RoadChiayi City 60004TaiwanPeople’s Republic of China Departm.nt of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Form.rly Departm.nt of Botany Goa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaGoa Velha 403108India Departm.nt of Crop Sciences College of Agricultural and Marine SciencesSultan Qaboos UniversityPO Box 8123 Al KhoudOman Sect.Environm.ntal Sciences Dept.MeSVAUniversity of L’Aquila67100 CoppitoAQItaly Division of Food Technology Biotechnology&AgrochemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186Korea Fungal Resources Research Division NNIBRSangju-si 37242Korea Westerdijk Fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands Departm.nt of Biotechnology and Biom.dicine DTUBioengineeringTechnical University of Denmark2800 Kongens LyngbyDenmark Botanischer Garten und Botanisches m.seum.Berlin Freie Universitat BerlinKonigin-Luise-StraßBe 6-814195 BerlinGermany Laboratorio de Botanica/Liquenologia Instituto de BiocienciasUniversidade Federal de Mato Grosso do SulAvenida Costa e Silva s/nBairro UniversitarioCampo GrandeMatto Grosso do Sul CEP 79070-900Brazil Departam.nto de Biociencias Universidade Federal de SergipeItabaianaSergipe CEP:49500-000Brazil Shenzhen Key Laboratory of m.crobial

This article is the tenth series of the Fungal Diversity Notes,where 114 taxa distributed in three phyla,ten classes,30 orders and 53 fam.lies are described and *** described in the present study include one new fam.ly(*** in Dothideom.cetes),five new genera(Caatingom.ces,Cryptoschizotrem.,Neoacladium.Param.ssaria and Trochilispora)and 71 new species,(*** thailandica,Am.iculicola aquatica,***,Angustim.ssarina sylvatica,Blackwellom.ces lateris,Boubovia gelatinosa,Buellia viridula,Caatingom.ces brasiliensis,Calophom. hum.li,Cam.rosporidiella m.ri,Canalisporium.dehongense,Cantharellus brunneopallidus,***,Castanediella m.liponae,Coprinopsis psam.ophila,Cordyceps succavus,Cortinarius m.nusculus,***,Diaporthe italiana,***,Diatrypella delonicis,Dictyocheirospora aquadulcis,***,Digitodesm.um.chiangm.iense,Distoseptispora dehongensis,***,Dothiorella styphnolobii,Ellisem.ia aurea,Falciform.spora aquatic,Fom.tiporia carpinea,***,Gram.othele aurantiaca,***,Herm.tom.ces bauhiniae,Jahnula queenslandica,Kam.lom.ces m.ngrovei,Lecidella yunnanensis,m.carea squam.losa,m.riphaeosphaeria angustifoliae,Neoacladium.indicum.Neodidym.lliopsis sam.uci,Neosetophom. m.scanthi,***,Nodulosphaeria aquilegiae,***,Param.ssaria sam.neae,Penicillium.circulare,***,***-pum.lae,***,***,Phaeoisaria siam.nsis,Phaeopoacea asparagicola,Phaeosphaeria penniseti,Plectocarpon galapagoense,Porina sorediata,Pseudoberkleasm.um.chiangm.iense,Pyrenochaetopsis sinensis,Rhizophydium.koreanum.Russula prasina,Sporoschism. chiangraiense,Stigm.tom.ces cham.em.iae,***,***,***,***,Thysanorea uniseptata,Torula breviconidiophora,***,Trochilispora schefflerae and Vaginatispora palm.e).Further,twelve new com.inations(*** cryptotrem.,Prolixandrom.ces australi,***,***,***,P.

关键词： 71 new taxa Ascom.cota Basidiom.cota Dothideom.cetes Eurotiom.cetes Lecanorom.cetes Leotiom.cetes Pezizom.cetes Phylogeny Taxonom.

Subclinical proxim.l tubulopathy in hepatitis B:The roles of nucleot(s)ide analogue treatm.nt and the hepatitis B virus

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World Journal of Hepatology 2020年第12期12卷 1326-1340页

作者： Anais Brayette m.rie Essig paul Carrier m.rilyne Debette-Gratien Anais Labrunie Sophie Alain m.rianne m.ynard Nathalie Ganne-Carrie Eric Nguyen-Khac pauline Pinet Victor De Ledinghen Christophe Renou Philippe m.thurin Claire Vanlem.ens Vincent Di m.rtino Anne Gervais Juliette Foucher Fouchard-Hubert Isabelle Julien Vergniol Isabelle Hourm.nd-Ollivier Daniel Cohen Xavier Duval Thierry Poynard m.rc Bardou Arm.nd Abergel m.nh-Thong Dao Thierry Thevenot Jean-Baptiste Hiriart Valerie Canva Guillaum. Lassailly Christine Aurières Nathalie Boyer Dom.nique Thabut Pierre-Henri Bernard m.tthieu Schnee Dom.nique Larrey Bertrand Hanslik Severine Hom.el Jerem.e Jacques Veronique Loustaud-Ratti U1248 INSERm Department of Hepatology and GastroenterologyUniv.LimogesCHU LimogesLimoges F-87000France U1248 INSERm Department of Nephrology and TransplantationCHU LimogesLimoges F-87000France Departm.nt of Center of Epidem.ology Biostatistics and Research MethodologyCHU LimogesLimoges F-87000France U1092 INSERm Department of VirologyCHU LimogesLimoges F-87000France Departm.nt of Hepatology Croix-Rousse University Hospital of LyonLyon 69004France Departm.nt of Hepatology Jean Verdier University Hospital of BondyBondy 93140France Departm.nt of Hepato-Gastroenterology Amiens University HospitalAmiens 80054France Departm.nt of Infectious Diseases CHU LimogesLimoges F-87000France Departm.nt of Hepatology Haut Leveque HospitalBordeaux University HospitalPessac 33604France Departm.nt of Gastroenterology Hyeres HospitalHyeres 83407France Departm.nt of Hepato-Gastroenterology Claude Huriez University HospitalLille 59037France Departm.nt of Hepatology Jean Minjoz University HospitalBesançon 25030France Departm.nt of Infectious Diseases Bichat University HospitalParis 75018France Departm.nt of Hepatology University Hospital of AngersAngers 49933France Departm.nt of Hepato-Gastroenterology and Nutrition University Hospital of CaenCaen 14033France Departm.nt of General m.decine University Hospital of CaenCaen 14000France Departm.nt of Hepatology La Pitié-Salpêtrière University HospitalParis 75651France Departm.nt of Hepatology and Gastroenterology Dijon University HospitalDijon 21079France Departm.nt of Hepatology and Gastroenterology Estaing University HospitalClermont Ferrand 63003France Departm.nt of Hepatology Beaujon University HospitalClichy 92110France Departm.nt of Hepatology Saint-AndréUniversity HospitalBordeaux 33000France Departm.nt of Hepatology and Gastroenterology La Roche-Sur-Yon Hospital CenterLa Roche-Sur-Yon 85000France Departm.nt of Hepatology and Gastroenterology University Hospital of MontpellierMontpellier 34295France Departm.nt of Addictology Hospita

BACKGROUND The recom.ended m.nitoring tools for evaluating nucleot(s)ide analogue renal toxicity,such as estim.ted glom.rular filtration rate(eGFR)and phosphatem.a,are late m.rkers of proxim.l *** early m.rkers are available,but no consensus exists on their *** To determ.ne the 24 m. prevalence of subclinical proxim.l tubulopathy(SPT),as defined with early biom.rkers,in treated vs untreated hepatitis B virus(HBV)-m.noinfected *** A prospective,non-random.zed,m.lticenter study of HBV-m.noinfected patients with a low num.er of renal com.rbidities was *** patients were separated into three groups:Naïve,starting entecavir(ETV)treatm.nt,or starting tenofovir disoproxil(TDF)*** on the early m.rkers of SPT,the eGFR and phosphatem.a,were collected *** was defined as a m.xim.l tubular reabsorption of phosphate/eGFR below 0.8 m.oL/L and/or uric acid fractional excretion above 10%.The prevalence and cum.lative incidence of SPT at m.nth 24(m.4)were *** data were analyzed using analyses of variance or Kruskal-Wallis tests,whereas chi-squared or Fisher’s exact tests were used to analyze qualitative *** analyses were used to adjust for any potential confounding *** Of the 196 patients analyzed,138(84 naïve,28 starting ETV,and 26 starting TDF)had no SPT at *** m.4,the prevalence of SPT was not statistically different between naïve and either treated group(21.1%vs 30.7%,Pm./m.n/1.73 m.or phosphatem.a less than 0.48 m.oL/*** the m.ltivariate analysis,no explanatory variables were identified after *** cum.lative incidence of SPT over 24 m.(25.5%,13.3%,and 52.9%in the naïve,ETV,and TDF groups,respectively)tended to be higher in the TDF group vs the naïve group(hazard ratio:2.283,P=0.05).SPT-free survival at m.4 was 57.6%,68.8%,and 23.5%for the naïve,ETV,and TD

关键词： Hepatitis B virus Proxim.l tubulopathy Biom.rkers Renal insufficiency Nucleoside analogues

基于小波的时间分辨CT灌注脑血管成像数据分析

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国际医学放射学杂志 2015年第5期 504-505页

作者： L.Havla K.m.Thierfelder S.E.Beyer W.H.Som.er O.Dietrich 曲方园 Josef-Lissner-Laboratory for Biom.dical Im.ging Institute for Clinical RadiologyLudwig-Maximilians-University Hospital Munich

摘要目的评价在CT灌注数据中应用小波变换重建血管成像的新方法。方法连续15例可疑脑卒中病人进行多层CT检查,得到99层(总层厚99 m.)动态32期(Δt=1.5 s)影像,扫描参数为80 k V/200 m.As。注射35 m.L碘美普尔350,流率4.5 m.L/s。利用时... 详细信息

摘要目的评价在CT灌注数据中应用小波变换重建血管成像的新方法。方法连续15例可疑脑卒中病人进行多层CT检查,得到99层(总层厚99 m.)动态32期(Δt=1.5 s)影像,扫描参数为80 k V/200 m.As。注射35 m.L碘美普尔350,流率4.5 m.L/s。利用时间滤过最大密度投影(t m.P)和每个体素时程的小波变换(paul wavelet,order 1)对血管成像数据进行

关键词：脑血管小波变换血管成像 CT

非洲大城市直接督导治疗的分散化管理:吉布提市的经验评价

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国际结核病与肺部疾病杂志 2003年第3期 109-114页

作者： J-J.Bernatas I.m.Ali H.A.Ism.■l A.B.m.tan I.H.Aboubakar 邹级谦 National Tuberculosis Program.e Ministry of Health Djibouti Djibouti

背景:2000年4月起,吉布提市3个公共卫生中心结核病人直接督导治疗(DOT)的分散化管理。目的:根据治疗地点、某些关键变量,以治疗成功率为指标对分散化管理进行评价。方法:对 2000年5月1日至 2001年3月31日期间,在所有治疗中心随访的涂阳... 详细信息

背景:2000年4月起,吉布提市3个公共卫生中心结核病人直接督导治疗(DOT)的分散化管理。目的:根据治疗地点、某些关键变量,以治疗成功率为指标对分散化管理进行评价。方法:对 2000年5月1日至 2001年3月31日期间,在所有治疗中心随访的涂阳病人治疗成功率进行比较评价。结果:主要治疗中心(paul Faure中心)的成功率为58％,其它所有地方中心的成功率为84％(P0.05)。在20岁以下年龄组,女性与治疗中心是成功率的相关因素。经分层分析,性别显示为混杂交量。多变量分析显示,非吉布提国籍与治疗成功相关(P=0.02)。在已建治疗中心与新建治疗中心,治疗成功率与工作负荷呈负线性相关,已建治疗中心的工作能力较强。结论:城区DOT的分散化管理提高了涂阳病人治疗成功的机会。需要在吉布提市的公共卫生中心再建立一所结核病督导治疗中心。

关键词： DOTS 分散化管理评价结核病吉布提

Association of m.neral and bone biom.rkers with adverse cardiovascular outcom.s and m.rtality in the Germ.n Chronic Kidney Disease(GCKD)cohort

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Bone Research 2023年第4期11卷 764-771页

作者： Katharina Charlotte Reim.r Jennifer Nadal Heike m.iselbach m.tthias Schm.d Ulla T.Schultheiss Fruzsina Kotsis Helena Stockm.nn Nele Friedrich m.tthias Nauck Vera Krane Kai-Uwe Eckardt m.rkus P.Schneider Rafael Kram.nn Jürgen Floege Turgay Saritas Departm.nt of Nephrology Rheumatologyand Clinical ImmunologyUniversity Hospital RWTH AachenAachenGermany Institute of Experim.ntal m.dicine and System. Biology RWTH Aachen UniversityAachenGermany Institute for Cell and Tum.r Biology RWTH Aachen UniversityAachenGermany Institute of m.dical Biom.try Informatics and EpidemiologyUniversity Hospital of BonnBonnGermany Departm.nt of Nephrology and Hypertension University of Erlangen-NürnbergErlangenGermany Institute of Genetic Epidem.ology Faculty of Medicine and Medical Center-University of FreiburgFreiburgGermany Departm.nt of m.dicine IV-Nephrology and Prim.ry Care Faculty of Medicine and Medical Center-University of FreiburgFreiburgGermany Departm.nt of Nephrology and m.dical Intensive Care Charité-Universitätsmedizin BerlinBerlinGermany Departm.nt of Nephrology University Medical Center RegensburgRegensburgGermany Institute of Clinical Chem.stry and Laboratory m.dicine University Medicine GreifswaldGreifswaldGermany DZHK(Germ.n Centre for Cardiovascular Research) Partner Site GreifswaldUniversity MedicineGreifswaldGermany Departm.nt of m.dicine I Division of NephrologyUniversity Hospital WürzburgWürzburgGermany

m.neral and bone disorder(m.D)in chronic kidney disease(CKD)is tightly linked to cardiovascular disease(CVD).In this study,we aim.d to com.are the prognostic value of nine m.D biom.rkers to determ.ne those associated best with adverse cardiovascular(CV)outcom.s and *** 5217 participants of the Germ.n CKD(GCKD)study enrolled with an estim.ted glom.rular filtration rate(eG FR)between 30–60 m.·m.n-1 per 1.73 m. or overt proteinuria,serum.osteoprotegerin(OPG),C-term.nal fibroblast growth factor-23(FGF23),intact parathyroid horm.ne(iP TH),bone alkaline phosphatase(BAP),cross-linked C-telopeptide of type 1 collagen(CTX1),procollagen 1intact N-term.nal propeptide(P1NP),phosphate,calcium.and 25-OH vitam.n D were m.asured at *** with m.ssing values am.ng these param.ters(n=971)were excluded,leaving a total of 4246 participants for *** a m.dian follow-up of6.5 years,387 non-CV deaths,173 CV deaths,645 nonfatal m.jor adverse CV events(m.CEs)and 368 hospitalizations for congestive heart failure(CHF)were *** and FGF23 were associated with all outcom.s,with the highest hazard ratios(HRs)for *** the final Cox regression m.del,adjusted for CV risk factors,including kidney function and all other investigated biom.rkers,each standard deviation increase in OPG was associated with non-CV death(HR 1.76,95%CI:1.35–2.30),CV death(HR 2.18,95%CI:1.50–3.16),m.CE(HR 1.38,95%CI:1.12–1.71)and hospitalization for CHF(HR 2.05,95%CI:1.56–2.69).Out of the nine biom.rkers exam.ned,stratification based on serum.OPG best identified the CKD patients who were at the highest risk for any adverse CV outcom. and m.rtality.

关键词： Kidney cardiovascular vitam.n

病房的新风置换系统:对于医院可持续方案设计的综合论述

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世界建筑 2010年第8期 110-117页

作者：保罗.马米恩雷.普拉迪纳克马克.特鲁多鲍勃.古利克阿尔希.吉蒂刘鹏飞加拿大斯坦泰克公司 m.NLB(m.zzetti Nash Lipsey Burch) m.NLB

1.摘要医院中病房内侧墙低位新风置换系统作为一种能减少运营成本以及初期投资的手段,在保障环境舒适性的同时提高通风能效,并有效地控制了感染的几率，因此在医疗卫生建筑中具有良好的推广前景。这项研究的目的在于考察新风置换系统（D... 详细信息

1.摘要医院中病房内侧墙低位新风置换系统作为一种能减少运营成本以及初期投资的手段,在保障环境舒适性的同时提高通风能效,并有效地控制了感染的几率，因此在医疗卫生建筑中具有良好的推广前景。这项研究的目的在于考察新风置换系统（DV）在一间医院病房中的工作模式。对于新风置换系统（DV）与顶部通风系统（OHV），在环境舒适性、空气粉尘（空气中病原体的附着载体）的散布控制两方面进行了测试和比较。在各种试验和观测结果的基础上建立数字模型．下一阶段则用于评估在不同动力学条件下新风置换系统的工作性能。

关键词：通风系统医院病房置换新风环境舒适性设计空气粉尘动力学条件

慢性阻塞性肺病:成像测量法能否解释肺气肿和呼吸道疾病的症状和运动能力?

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国际医学放射学杂志 2016年第1期 80-81页

作者： m.Kirby D.Pike D.D.Sin H.O.Coxson D.G.m. Corm.ck G.Parraga 顾康康 Jam.s Hogg Research Centre The University of British Columbia and the Institute of Heart and Lung HealthSt Paul ’s Hospital

摘要目的确定成像测量法在轻度或中度肺气肿和呼吸道疾病中决定慢性阻塞性肺病（COPD）的症状和运动受限程度的作用。材料与方法受试者（n=116）为全球招募的COPD病人（GOLD）U级（未分类）或ⅠⅣ级,签署经伦理委员会批准的知情同意书... 详细信息

摘要目的确定成像测量法在轻度或中度肺气肿和呼吸道疾病中决定慢性阻塞性肺病（COPD）的症状和运动受限程度的作用。材料与方法受试者（n=116）为全球招募的COPD病人（GOLD）U级（未分类）或ⅠⅣ级,签署经伦理委员会批准的知情同意书并符合HIPAA协议。所有受试者接受肺容量测定和体积描记,完成St George呼吸问卷（SGRQ）,完成6 m.n步行试验,记录6 m.n步行距离（6m.D）,进行超极化3He-m.I和CT检查。采用m.I表观扩散系数（ADC）和CT衰减直方图[衰减值取-950 HU或更小值(RA950)]上的相

关键词：肺气肿中度肺疾病慢性阻塞性成像测量 COPD 呼吸道疾病

可疑患有冠状动脉疾病且无可干预危险因素的稳定人群的心血管疾病风险:一项包括5262例病人的国际多中心研究结果

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国际医学放射学杂志 2013年第4期 377-378页

作者： J. Leipsic C.m. Taylor G. Grunau B.G. Heilbron G.B.J. m.ncini S. Achenbach 毛子婧 Departm.nt of m.dical Im.ging and Division of Cardiology St. Paul's Hospital University of British Columbia1081 Burrard St Vancouver BC Canada V6S 1Y6

目的评估可疑患有冠状动脉疾病（CAD）且无可医学干预危险因素的病人罹患CAD的发病率、范围、严重程度及其风险。材料与方法本研究获各医学中心的机构审查委员会批准,免除知情同意,并且符合HIPAA标准。自一项包括12个中心27125名受试者... 详细信息

目的评估可疑患有冠状动脉疾病（CAD）且无可医学干预危险因素的病人罹患CAD的发病率、范围、严重程度及其风险。材料与方法本研究获各医学中心的机构审查委员会批准,免除知情同意,并且符合HIPAA标准。自一项包括12个中心27125名受试者的国际多中心队列研究中筛选出5262例病人,要求病人无CAD病史且无可干预的危险因素,均行冠状动脉CT血管成像。分别基于每例病人,基于每条血管,基于血管的各个节段,将CAD的严重程度划分为无（0%）、轻度（1%49%）和闭塞（≥50%）3个级别。应用Cox比例风险模型将CAD及其范围、严重程度与较大的心血管不良事件（m.CE）进行关联性分析。结果在平均（2.3±1.2）年随访期间,106例病人发生m.CE。CAD常见于两种类型,非闭塞性CAD（n=1452,27%）和闭塞性CAD（n=629,12%）。在风险校正后的分析中,病人的闭塞性CAD与m.CE相关[风险比（HR）,6.64;95%CI:3.68～12.00;P≤0.001]。m.CE与发生闭塞性CAD的血管数量呈量效反应关系,单支血管闭塞的CAD风险增加（HR,6.11;95%CI:3.22～11.6;P≤0.001）,2支血管闭塞的CAD（HR,5.86;95%CI:2.75～12.5;P≤0.0001）,3支血管或左主干闭塞的CAD（HR,11.69;95%CI:5.38～25.4;P≤0.001）。m.CE风险增加既见于有症状（HR,11.9;95%CI:4.81～29.6;P≤0.001）也见于无症状（HR,6.3;95%CI:2.4～16.7;P≤0.001）的病人。冠状动脉CT血管成像无CAD病人的m.CE年发生率低于有闭塞性CAD病人,分别为0.31%和2.06%。结论可疑患有CAD但无可干预危险因素个体常常罹患CAD,发生m.CE的风险和死亡率显著增加。原文载于Radiology,2013,267（3）:718-726.

关键词：冠状动脉疾病闭塞性病人 m.CE CAD

食物蛋白诱导性小肠结肠炎综合征诊断和治疗国际共识指南

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中华临床免疫和变态反应杂志 2018年第1期12卷 109-123页

作者： Anna Nowak-We.grzyn m.rnaChehade m.rion E.Groetch Jonathan m.Spergel Robert A.Wood Katrina Allen Dan Atkins Sam. Bahna Ashis V.Barad Cecilia Berin Terri Brown Whitehorn A.Wesley Burks Jean-Christoph Caubet Antonella Cianferoni m.risa Conte Carla Davis Alessandro Fiocchi Kate Grim.haw RNutr Ruchi Gupta Brittany Hofm.ister J.B.Hwang Yitzhak Katz George N.Konstantinou Stephanie A.Leonard Jennifer Lightdale Sean m.Ghee Sam. m.hr Stefano m.celiSopo Giovanno m.nti Antonella m.raro Stacey Katherine Noel Ichiro Nom.ra Sally Noone Hugh A.Sam.son Fallon Schultz Scott H.Sicherer Cecilia C.Thom.son paul J.Turner Carina Venter A.Am.ty Westcott-Chavez m.tthew Greenhawt 李丽莎钱家鸣杨红不详中国医学科学院北京协和医学院北京协和医院变态(过敏)反应科中国医学科学院北京协和医学院北京协和医院消化内科

食物蛋白诱导性小肠结肠炎综合征（food protein-induced enterocolitis, FPIES）是一种非IgE,细胞介导的食物过敏反应,其表现可以很严重,甚至导致休克。虽然该类过敏反应有潜在的严重性,但FPIES 的知晓率却较低；而且有关FPIES 病理生... 详细信息

食物蛋白诱导性小肠结肠炎综合征（food protein-induced enterocolitis, FPIES）是一种非IgE,细胞介导的食物过敏反应,其表现可以很严重,甚至导致休克。虽然该类过敏反应有潜在的严重性,但FPIES 的知晓率却较低；而且有关FPIES 病理生理学,诊断和治疗的高质量研究数据缺乏；其临床预后尚不明确。这篇国际共识由美国变态反应、哮喘和免疫学会（AAAAI）食物不良反应委员会和国际FPIES 协会宣传组召集组织国际工作组总结撰写。这是第一部基于临床证据的FPIES 国际指南,有助于提高FPIES 的临床诊治水平。当然未来还需要更多有关FPIES 患病率,病理生理学,诊断标志物和未来治疗方法的研究,以便为FPIES 患者提供更好的医疗服务。这些指南内容将会在获得更多证据后定期更新。

关键词：食物蛋白诱导性小肠结肠炎综合征指南非IgE 介导的食物过敏